Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Tumor necrosis factor1477 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A19890 | 26281602 | Zhongguo Zhong Yao Za Zhi | [Intervention effect and mechanism of compound Ginkgo biloba preparations on nonalcoholic fatty liver]. | 2015 | Details |
| A19939 | 26253086 | Clin Sci (Lond) | CX3CR1-expressing inflammatory dendritic cells contribute to the progression of steatohepatitis. | 2015 | Details |
| A19949 | 26246326 | J Nutr | Oral Glutamine Supplementation Protects Female Mice from Nonalcoholic Steatohepatitis. | 2015 | Details |
| A19982 | 26226139 | PLoS One | Fish Oil Supplements Lower Serum Lipids and Glucose in Correlation with a Reduction in Plasma Fibroblast Growth Factor 21 and Prostaglandin E2 in Nonalcoholic Fatty Liver Disease Associated with Hyperlipidemia: A Randomized Clinical Trial. | 2015 | Details |
| A20006 | 26212089 | J Gastroenterol Hepatol | Small intestinal bacterial overgrowth and toll-like receptor signaling in patients with non-alcoholic fatty liver disease. | 2016 | Details |
| A20025 | 26201023 | Clin Sci (Lond) | Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis. | 2015 | Details |
| A20041 | 26194065 | Cytokine | PPARα/γ agonists and antagonists differently affect hepatic lipid metabolism, oxidative stress and inflammatory cytokine production in steatohepatitic rats. | 2015 | Details |
| A20060 | 26186426 | J Med Food | Short- and Long-Term Soy Diet Versus Casein Protects Liver Steatosis Independent of the Arginine Content. | 2015 | Details |
| A20098 | 26156412 | J Am Coll Nutr | Functions of Coenzyme Q10 Supplementation on Liver Enzymes, Markers of Systemic Inflammation, and Adipokines in Patients Affected by Nonalcoholic Fatty Liver Disease: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial. | 2015 | Details |
| A20100 | 26155043 | J Clin Exp Hepatol | The Riddle of Nonalcoholic Fatty Liver Disease: Progression From Nonalcoholic Fatty Liver to Nonalcoholic Steatohepatitis. | 2015 | Details |
| A20110 | 26148245 | Eur J Gastroenterol Hepatol | Nonalcoholic fatty liver disease: a potential consequence of tumor necrosis factor-inhibitor therapy. | 2015 | Details |
| A20116 | 26146507 | Evid Based Complement Alternat Med | Hugan Qingzhi Exerts Anti-Inflammatory Effects in a Rat Model of Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20118 | 26143342 | Dig Dis Sci | Lactobacillus paracasei Induces M2-Dominant Kupffer Cell Polarization in a Mouse Model of Nonalcoholic Steatohepatitis. | 2015 | Details |
| A20124 | 26139990 | World J Gastroenterol | Altered distribution of regulatory lymphocytes by oral administration of soy-extracts exerts a hepatoprotective effect alleviating immune mediated liver injury, non-alcoholic steatohepatitis and insulin resistance. | 2015 | Details |
| A20131 | 26137185 | Oxid Med Cell Longev | Choline and Cystine Deficient Diets in Animal Models with Hepatocellular Injury: Evaluation of Oxidative Stress and Expression of RAGE, TNF-α, and IL-1β. | 2015 | Details |
| A20134 | 26134756 | Pharm Biol | Protective effect of ursodeoxycholic acid, resveratrol, and N-acetylcysteine on nonalcoholic fatty liver disease in rats. | 2015 | Details |
| A20139 | 26133108 | Clin Transl Gastroenterol | Increased Serum Levels of LIGHT/TNFSF14 in Nonalcoholic Fatty Liver Disease: Possible Role in Hepatic Inflammation. | 2015 | Details |
| A20173 | 26112094 | Exp Mol Pathol | Fat-laden macrophages modulate lobular inflammation in nonalcoholic steatohepatitis (NASH). | 2015 | Details |
| A20188 | 26097546 | Int J Clin Exp Pathol | Intestinal mucosal barrier dysfunction participates in the progress of nonalcoholic fatty liver disease. | 2015 | Details |
| A20213 | 26080824 | Zhonghua Nei Ke Za Zhi | [Myosin light chain kinase involved in change of intestinal mucosal barrier function in nonalcoholic steatohepatitis mice model]. | 2015 | Details |
| A20266 | 26055348 | Nutr Res | Resveratrol prevents hepatic steatosis and endoplasmic reticulum stress and regulates the expression of genes involved in lipid metabolism, insulin resistance, and inflammation in rats. | 2015 | Details |
| A20284 | 26045709 | Hepat Mon | Saturated Fatty Acid inhibits viral replication in chronic hepatitis B virus infection with nonalcoholic Fatty liver disease by toll-like receptor 4-mediated innate immune response. | 2015 | Details |
| A20291 | 26043290 | Eur J Gastroenterol Hepatol | Efficacy of rifaximin on circulating endotoxins and cytokines in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A20314 | 26033364 | Exp Cell Res | MicroRNA-101 overexpression by IL-6 and TNF-α inhibits cholesterol efflux by suppressing ATP-binding cassette transporter A1 expression. | 2015 | Details |
| A20316 | 26032587 | Pharmacol Res | Dihydromyricetin improves glucose and lipid metabolism and exerts anti-inflammatory effects in nonalcoholic fatty liver disease: A randomized controlled trial. | 2015 | Details |
| A20321 | 28210688 | Cell Mol Gastroenterol Hepatol | Alcoholic, Nonalcoholic, and Toxicant-Associated Steatohepatitis: Mechanistic Similarities and Differences. | 2015 | Details |
| A20322 | 26028579 | Gastroenterology | Association of Adipose Tissue Inflammation With Histologic Severity of Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20340 | 26021772 | Saudi J Gastroenterol | The relationship of circulating fetuin-a with liver histology and biomarkers of systemic inflammation in nondiabetic subjects with nonalcoholic fatty liver disease. | 2016 | Details |
| A20355 | 26018806 | Mol Med | Galectin-3 Ablation Enhances Liver Steatosis, but Attenuates Inflammation and IL-33-Dependent Fibrosis in Obesogenic Mouse Model of Nonalcoholic Steatohepatitis. | 2015 | Details |
| A20356 | 26018346 | Mol Med Rep | Intrahepatic transplantation of adipose-derived stem cells attenuates the progression of non-alcoholic fatty liver disease in rats. | 2015 | Details |
| A20367 | 26011302 | Metab Syndr Relat Disord | Insulin Resistance but Not Visceral Adiposity Index Is Associated with Liver Fibrosis in Nondiabetic Subjects with Nonalcoholic Fatty Liver Disease. | 2015 | Details |
| A20379 | 26003186 | Eur J Nutr | Moderate alcohol consumption diminishes the development of non-alcoholic fatty liver disease (NAFLD) in ob/ob mice. | 2015 | Details |
| A20412 | 25984739 | Nutrients | MiRNA-194 Regulates Palmitic Acid-Induced Toll-Like Receptor 4 Inflammatory Responses in THP-1 Cells. | 2015 | Details |
| A20437 | 25966055 | Genet Mol Res | Role of APN and TNF-α in type 2 diabetes mellitus complicated by nonalcoholic fatty liver disease. | 2015 | Details |
| A20447 | 25957914 | Int J Biochem Cell Biol | Downregulation of microRNA-451 in non-alcoholic steatohepatitis inhibits fatty acid-induced proinflammatory cytokine production through the AMPK/AKT pathway. | 2015 | Details |
| A20450 | 25956613 | Hepatol Int | Comparative clinical study between the effect of fenofibrate alone and its combination with pentoxifylline on biochemical parameters and liver stiffness in patients with non-alcoholic fatty liver disease. | 2015 | Details |
| A20457 | 25948763 | Acta Med Indones | Combination of Aspartate Aminotranferase and Tumor Necrosis Factor-α as Non Invasive Diagnostic Tools for Non Alcoholic Steatohepatitis (NASH). | 2015 | Details |
| A20460 | 25947915 | Biol Pharm Bull | The Glucagon-Like Peptide-1 Analogue Liraglutide Inhibits Oxidative Stress and Inflammatory Response in the Liver of Rats with Diet-Induced Non-alcoholic Fatty Liver Disease. | 2015 | Details |
| A20472 | 25940288 | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi | [Emodin worsens methionine-choline-deficient diet-induced non-alcoholic fatty liver disease in mice]. | 2015 | Details |
| A20494 | 25922835 | Biomed Res Int | Antiresistin RNA Oligonucleotide Ameliorates Diet-Induced Nonalcoholic Fatty Liver Disease in Mice through Attenuating Proinflammatory Cytokines. | 2015 | Details |
| A20508 | 25916635 | Biochim Biophys Acta | Carbon monoxide protects against hepatic ischemia/reperfusion injury by modulating the miR-34a/SIRT1 pathway. | 2015 | Details |
| A20527 | 25910299 | Turk J Gastroenterol | A comparison of the effects of infliximab, adalimumab, and pentoxifylline on rats with non-alcoholic steatohepatitis. | 2014 | Details |
| A20529 | 25909884 | Cell Death Differ | Hepatocyte-specific Bid depletion reduces tumor development by suppressing inflammation-related compensatory proliferation. | 2015 | Details |
| A20531 | 25906757 | J Endocrinol Invest | 1,25(OH)2D3 downregulates the Toll-like receptor 4-mediated inflammatory pathway and ameliorates liver injury in diabetic rats. | 2015 | Details |
| A20545 | 25896720 | Pharmacology | Fenofibrate treatment attenuated chronic endoplasmic reticulum stress in the liver of nonalcoholic fatty liver disease mice. | 2015 | Details |
| A20548 | 25894568 | Clin Exp Med | Severity of non-alcoholic fatty liver disease is associated with high systemic levels of tumor necrosis factor alpha and low serum interleukin 10 in morbidly obese patients. | 2015 | Details |
| A20560 | 25886887 | BMC Gastroenterol | Fluvastatin attenuates hepatic steatosis-induced fibrogenesis in rats through inhibiting paracrine effect of hepatocyte on hepatic stellate cells. | 2015 | Details |
| A20581 | 25873773 | Mediators Inflamm | OSAS-related inflammatory mechanisms of liver injury in nonalcoholic fatty liver disease. | 2015 | Details |
| A20596 | 25865685 | Hepatobiliary Pancreat Dis Int | Beneficial mechanisms of aerobic exercise on hepatic lipid metabolism in non-alcoholic fatty liver disease. | 2015 | Details |
| A20657 | 25825591 | Hepat Mon | Association of Tumor Necrosis Factor-alpha Polymorphisms and Risk of Coronary Artery Disease in Patients With Non-alcoholic Fatty Liver Disease. | 2015 | Details |
| A20669 | 25817233 | Life Sci | AMP-kinase pathway is involved in tumor necrosis factor alpha-induced lipid accumulation in human hepatoma cells. | 2015 | Details |
| A20734 | 25771129 | Toxicol Appl Pharmacol | Antenatal exposure to the selective serotonin reuptake inhibitor fluoxetine leads to postnatal metabolic and endocrine changes associated with type 2 diabetes in Wistar rats. | 2015 | Details |
| A20737 | 25767392 | Ther Clin Risk Manag | Therapeutic effect of hybrid training of voluntary and electrical muscle contractions in middle-aged obese women with nonalcoholic fatty liver disease: a pilot trial. | 2015 | Details |
| A20739 | 25766252 | Sci Rep | Lipidomic-based investigation into the regulatory effect of Schisandrin B on palmitic acid level in non-alcoholic steatotic livers. | 2015 | Details |
| A20754 | 25755546 | J Clin Exp Hepatol | Metadoxine Versus Placebo for the Treatment of Non-alcoholic Steatohepatitis: A Randomized Controlled Trial. | 2014 | Details |
| A20759 | 25751957 | Zhongguo Zhong Yao Za Zhi | [Effects of soothing liver and invigorating spleen recipes on LPS-induced hepatocytes injury of rats and TLR4/p38MAPK signal pathway]. | 2014 | Details |
| A20787 | 25736031 | Clin Nutr | Effect of specific amino acids on hepatic lipid metabolism in fructose-induced non-alcoholic fatty liver disease. | 2015 | Details |
| A20810 | 25717238 | World J Gastroenterol | Mechanism of action of gypenosides on type 2 diabetes and non-alcoholic fatty liver disease in rats. | 2015 | Details |
| A20827 | 25708949 | Naunyn Schmiedebergs Arch Pharmacol | Protective effect of boswellic acids versus pioglitazone in a rat model of diet-induced non-alcoholic fatty liver disease: influence on insulin resistance and energy expenditure. | 2015 | Details |
| A20859 | 25681756 | Exp Mol Pathol | Resolvin E1 and chemerin C15 peptide do not improve rodent non-alcoholic steatohepatitis. | 2015 | Details |
| A20885 | 25664838 | Nutr Diabetes | Determining the association between adipokine expression in multiple tissues and phenotypic features of non-alcoholic fatty liver disease in obesity. | 2015 | Details |
| A20894 | 25658238 | Nutrients | 6-gingerol protects against nutritional steatohepatitis by regulating key genes related to inflammation and lipid metabolism. | 2015 | Details |
| A20902 | 25654291 | Zhonghua Gan Zang Bing Za Zhi | [Impact of JNK inhibitor XG-102 in a diet-induced rat model of non-alcoholic steatohepatitis]. | 2014 | Details |
| A20903 | 25654290 | Zhonghua Gan Zang Bing Za Zhi | [Association of intestinal epithelial tight junctions, E.coli, intestinal mucosa Toll-like receptor-4 and tumor necrosis factor-alpha in rabbit with non-alcoholic fatty liver disease]. | 2014 | Details |
| A20921 | 25644696 | Sci Rep | Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans with non-alcoholic fatty liver disease. | 2015 | Details |
| A20929 | 25634387 | Indian Heart J | Prevalence of nonalcoholic fatty liver disease (NAFLD) in patients of cardiovascular diseases and its association with hs-CRP and TNF-α. | 2014 | Details |
| A21041 | 25561778 | World J Gastroenterol | Adipokines and proinflammatory cytokines, the key mediators in the pathogenesis of nonalcoholic fatty liver disease. | 2014 | Details |
| A21044 | 25559563 | J Gastroenterol Hepatol | MiR-146b attenuates high-fat diet-induced non-alcoholic steatohepatitis in mice. | 2015 | Details |
| A21064 | 27453880 | J Diabetes Metab Disord | The effects of onion consumption on treatment of metabolic, histologic, and inflammatory features of nonalcoholic fatty liver disease. | 2016 | Details |
| A21089 | 25542756 | Eur J Pharmacol | Ameliorative effect of nicorandil on high fat diet induced non-alcoholic fatty liver disease in rats. | 2014 | Details |
| A21091 | 25541279 | Prostaglandins Leukot Essent Fatty Acids | Ameliorative potential of omega 3 fatty acids and HMG-CoA reductase inhibitors on experimentally-induced non-alcoholic steatohepatitis. | 2014 | Details |
| A21122 | 25528857 | Lik Sprava | [Hyperhomocysteinemia--a predictor of inflammatory changes in the liver]. | 2014 | Details |
| A21135 | 25523099 | Exp Mol Med | Omega-3 polyunsaturated fatty acid and ursodeoxycholic acid have an additive effect in attenuating diet-induced nonalcoholic steatohepatitis in mice. | 2014 | Details |
| A21140 | 25520925 | Biomedicine (Taipei) | Auricularia polytricha aqueous extract supplementation decreases hepatic lipid accumulation and improves antioxidative status in animal model of nonalcoholic fatty liver. | 2014 | Details |
| A21221 | 25470242 | PLoS One | Neurotropin suppresses inflammatory cytokine expression and cell death through suppression of NF-κB and JNK in hepatocytes. | 2014 | Details |
| A21231 | 25468788 | Med Hypotheses | Pentoxifylline in the management of metabolic syndrome and chronic hepatitis C. | 2014 | Details |
| A21267 | 25446569 | Eur J Pharmacol | Naringenin reduces cholesterol-induced hepatic inflammation in rats by modulating matrix metalloproteinases-2, 9 via inhibition of nuclear factor κB pathway. | 2014 | Details |
| A21312 | 25413450 | Metab Brain Dis | Low-grade chronic inflammation induces behavioral stereotypy in rats. | 2014 | Details |
| A21318 | 25410681 | BMC Gastroenterol | High-saturate-fat diet delays initiation of diethylnitrosamine-induced hepatocellular carcinoma. | 2014 | Details |
| A21322 | 25406833 | J Transl Med | Hepatoprotective and antioxidant activities of extracts from Salvia-Nelumbinis naturalis against nonalcoholic steatohepatitis induced by methionine- and choline-deficient diet in mice. | 2014 | Details |
| A21325 | 25404857 | Ther Clin Risk Manag | Acceleration training for managing nonalcoholic fatty liver disease: a pilot study. | 2014 | Details |
| A21373 | 25367327 | Food Funct | Effects of Callistephus chinensis flower polyphones on improving metabolic disorders in high-fat diet-induced mice. | 2014 | Details |
| A21389 | 25353663 | Nutrients | Effects of dietary fat and saturated fat content on liver fat and markers of oxidative stress in overweight/obese men and women under weight-stable conditions. | 2014 | Details |
| A21391 | 25352871 | Afr Health Sci | Markers of liver function and inflammatory cytokines modulation by aerobic versus resisted exercise training for nonalcoholic steatohepatitis patients. | 2014 | Details |
| A21410 | 25341597 | Turk J Pediatr | Leptin-to-adiponectin ratio in obese adolescents with nonalcoholic fatty liver disease. | 2016 | Details |
| A21434 | 25319795 | Int J Mol Med | Obesity increases histone H3 lysine 9 and 18 acetylation at Tnfa and Ccl2 genes in mouse liver. | 2014 | Details |
| A21439 | 25317812 | Eur Rev Med Pharmacol Sci | The impact of small doses of LPS on NASH in high sucrose and high fat diet induced rats. | 2014 | Details |
| A21511 | 25266069 | J Diabetes | Alanine transferase: An independent indicator of adiposity related comorbidity risk in youth. | 2014 | Details |
| A21556 | 25232450 | World J Hepatol | Role of adipokines and peroxisome proliferator-activated receptors in nonalcoholic fatty liver disease. | 2014 | Details |
| A21572 | 25219124 | Zhen Ci Yan Jiu | [Effect of electroacupuncture stimulation of back-shu points on expression of TNF-alpha and lipid peroxidation reaction in the liver tissue in non-alcoholic fatty liver disease rats]. | 2014 | Details |
| A21617 | 25183508 | Acta Physiol Hung | Naltrexone attenuates endoplasmic reticulum stress induced hepatic injury in mice. | 2014 | Details |
| A21622 | 25180626 | Mol Med | Binge alcohol consumption aggravates oxidative stress and promotes pathogenesis of NASH from obesity-induced simple steatosis. | 2014 | Details |
| A21668 | 25136608 | Biomed Res Int | Ruscogenin ameliorates experimental nonalcoholic steatohepatitis via suppressing lipogenesis and inflammatory pathway. | 2014 | Details |
| A21772 | 25057104 | Nutrients | Pinus densiflora Sieb. et Zucc. alleviates lipogenesis and oxidative stress during oleic acid-induced steatosis in HepG2 cells. | 2014 | Details |
| A21777 | 25051240 | Metab Syndr Relat Disord | Evaluation of clinical and inflammatory markers of nonalcoholic fatty liver disease in postmenopausal women with metabolic syndrome. | 2014 | Details |
| A21782 | 25048611 | PLoS One | Inflammatory stress increases hepatic CD36 translational efficiency via activation of the mTOR signalling pathway. | 2014 | Details |
| A21817 | 25024607 | World J Gastroenterol | High fat diet feeding results in gender specific steatohepatitis and inflammasome activation. | 2014 | Details |
| A21860 | 24993341 | Int Immunopharmacol | Involvement of hepatic peroxisome proliferator-activated receptor α/γ in the therapeutic effect of osthole on high-fat and high-sucrose-induced steatohepatitis in rats. | 2014 | Details |
| A21871 | 24988316 | PLoS One | Non-invasive separation of alcoholic and non-alcoholic liver disease with predictive modeling. | 2014 | Details |
| A21877 | 24985011 | Nutrition | Resveratrol attenuates hepatic steatosis in high-fat fed mice by decreasing lipogenesis and inflammation. | 2013 | Details |