Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A04025 | 33785339 | Life Sci | A rapid juvenile murine model of nonalcoholic steatohepatitis (NASH): Chronic intermittent hypoxia exacerbates Western diet-induced NASH. | 2021 | Details |
| A04029 | 33784797 | Phytother Res | Isotschimgine alleviates nonalcoholic steatohepatitis and fibrosis via FXR agonism in mice. | 2021 | Details |
| A04044 | 33777700 | Toxicol Rep | Polychlorinated biphenyls altered gut microbiome in CAR and PXR knockout mice exhibiting toxicant-associated steatohepatitis. | 2021 | Details |
| A04048 | 33776901 | Front Endocrinol (Lausanne) | Dietary Oxysterol, 7-Ketocholesterol Accelerates Hepatic Lipid Accumulation and Macrophage Infiltration in Obese Mice. | 2021 | Details |
| A04054 | 33775752 | Virus Res | The identify role and molecular mechanism of the MALAT1/hsa-mir-20b-5p/TXNIP axis in liver inflammation caused by CHB in patients with chronic HBV infection complicated with NAFLD. | 2021 | Details |
| A04058 | 33773656 | Food Res Int | Dietary anthocyanins as potential natural modulators for the prevention and treatment of non-alcoholic fatty liver disease: A comprehensive review. | 2021 | Details |
| A04059 | 33773468 | Biomed Pharmacother | 4-Acetylantroquinonol B ameliorates nonalcoholic steatohepatitis by suppression of ER stress and NLRP3 inflammasome activation. | 2021 | Details |
| A04060 | 33773192 | Phytomedicine | Si Miao Formula attenuates non-alcoholic fatty liver disease by modulating hepatic lipid metabolism and gut microbiota. | 2021 | Details |
| A04063 | 33772456 | Indian J Gastroenterol | Efficacy of combining pentoxiphylline and vitamin E versus vitamin E alone in non-alcoholic steatohepatitis- A randomized pilot study. | 2021 | Details |
| A04072 | 33769703 | Physiol Rep | ω-Imidazolyl-alkyl derivatives as new preclinical drug candidates for treating non-alcoholic steatohepatitis. | 2021 | Details |
| A04076 | 33768700 | J Dtsch Dermatol Ges | Non-alcoholic fatty liver disease and psoriasis - is there a shared proinflammatory network? | 2021 | Details |
| A04087 | 33765728 | Clin Endosc | Fecal Microbiota Transplantation beyond Clostridioides Difficile Infection. | 2021 | Details |
| A04091 | 33763027 | Front Endocrinol (Lausanne) | Association and Interaction Between Serum Interleukin-6 Levels and Metabolic Dysfunction-Associated Fatty Liver Disease in Patients With Severe Coronavirus Disease 2019. | 2021 | Details |
| A04095 | 33762390 | Clin Med (Lond) | Hydrogen treatment: a novel option in liver diseases. | 2021 | Details |
| A04098 | 33761609 | Biomed Pharmacother | Ethyl pyruvate supplemented in drinking water ameliorates experimental nonalcoholic steatohepatitis. | 2021 | Details |
| A04110 | 33753727 | Cell Death Dis | S-adenosylmethionine upregulates the angiotensin receptor-binding protein ATRAP via the methylation of HuR in NAFLD. | 2021 | Details |
| A04115 | 33751907 | J Med Food | A Comparison of Short- and Long-Term Soy Protein Isolate Intake and Its Ability to Reduce Liver Steatosis in Obese Zucker Rats Through Modifications of Genes Involved in Inflammation and Lipid Transport. | 2021 | Details |
| A04117 | 33751456 | Curr Obes Rep | Endoplasmic Reticulum Stress and Autophagy in the Pathogenesis of Non-alcoholic Fatty Liver Disease (NAFLD): Current Evidence and Perspectives. | 2021 | Details |
| A04120 | 33750416 | J Transl Med | LncRNA-Gm9795 promotes inflammation in non-alcoholic steatohepatitis via NF-[Formula: see text]B/JNK pathway by endoplasmic reticulum stress. | 2021 | Details |
| A04169 | 33730435 | Hepatology | In Utero Exposure to Mercury Is Associated With Increased Susceptibility to Liver Injury and Inflammation in Childhood. | 2021 | Details |
| A04176 | 33727658 | Commun Biol | Adiponectin-expressing Treg facilitate T lymphocyte development in thymic nurse cell complexes. | 2021 | Details |
| A04192 | 33721354 | Clin Exp Pharmacol Physiol | Sodium butyrate ameliorates non-alcoholic fatty liver disease by upregulating miR-150 to suppress CXCR4 expression. | 2021 | Details |
| A04193 | 33720620 | Ter Arkh | [Hepatocellular damage and inflammation in various forms of alcoholic liver disease]. | 2021 | Details |
| A04198 | 33720049 | J Clin Invest | VCAM-1: closing the gap between lipotoxicity and endothelial dysfunction in nonalcoholic steatohepatitis. | 2021 | Details |
| A04200 | 33718398 | Front Med (Lausanne) | Oxidative Stress in Non-alcoholic Fatty Liver Disease. An Updated Mini Review. | 2021 | Details |
| A04206 | 33714861 | Complement Ther Clin Pract | Effect of green coffee bean extract supplementation on liver function and inflammatory biomarkers: A meta-analysis of randomized clinical trials. | 2021 | Details |
| A04226 | 33708118 | Front Pharmacol | Astragaloside IV Improves High-Fat Diet-Induced Hepatic Steatosis in Nonalcoholic Fatty Liver Disease Rats by Regulating Inflammatory Factors Level via TLR4/NF-κB Signaling Pathway. | 2021 | Details |
| A04234 | 33703947 | J Appl Physiol (1985) | High fat high sucrose diet-induced dyslipidemia in guinea pigs. | 2021 | Details |
| A04236 | 33694066 | Hepatol Int | Does the risk of cardiovascular events differ between biopsy-proven NAFLD and MAFLD? | 2021 | Details |
| A04237 | 33693900 | J Nutr | Consumption of High-Fructose Corn Syrup Compared with Sucrose Promotes Adiposity and Increased Triglyceridemia but Comparable NAFLD Severity in Juvenile Iberian Pigs. | 2021 | Details |
| A04238 | 33693866 | J Nutr | Hepatoprotective Effects of Indole, a Gut Microbial Metabolite, in Leptin-Deficient Obese Mice. | 2021 | Details |
| A04243 | 33692776 | Front Immunol | TGR5 Regulates Macrophage Inflammation in Nonalcoholic Steatohepatitis by Modulating NLRP3 Inflammasome Activation. | 2021 | Details |
| A04244 | 33692700 | Front Physiol | Characterization of the CDAA Diet-Induced Non-alcoholic Steatohepatitis Model: Sex-Specific Differences in Inflammation, Fibrosis, and Cholesterol Metabolism in Middle-Aged Mice. | 2021 | Details |
| A04249 | 33690979 | Small | Bioengineered Multicellular Liver Microtissues for Modeling Advanced Hepatic Fibrosis Driven Through Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A04251 | 33689215 | J Cell Mol Med | Inhibition of miR-188-5p alleviates hepatic fibrosis by significantly reducing the activation and proliferation of HSCs through PTEN/PI3K/AKT pathway. | 2021 | Details |
| A04278 | 33679403 | Front Pharmacol | Ginsenosides Improve Nonalcoholic Fatty Liver Disease via Integrated Regulation of Gut Microbiota, Inflammation and Energy Homeostasis. | 2021 | Details |
| A04285 | 33678036 | Hum Exp Toxicol | Early intervention with probiotics and metformin alleviates liver injury in NAFLD rats via targeting gut microbiota dysbiosis and p-AKT/mTOR/LC-3II pathways. | 2021 | Details |
| A04290 | 33675573 | J Dig Dis | Liver and serum adiponectin levels in non-alcoholic fatty liver disease. | 2021 | Details |
| A04293 | 33674694 | Sci Rep | DSS-induced colitis is associated with adipose tissue dysfunction and disrupted hepatic lipid metabolism leading to hepatosteatosis and dyslipidemia in mice. | 2021 | Details |
| A04300 | 33672787 | Int J Mol Sci | Absence of Adiponutrin (PNPLA3) and Monoacylglycerol Lipase Synergistically Increases Weight Gain and Aggravates Steatohepatitis in Mice. | 2021 | Details |
| A04302 | 33671926 | Int J Mol Sci | Sarcopenic Obesity in Liver Cirrhosis: Possible Mechanism and Clinical Impact. | 2021 | Details |
| A04303 | 33671880 | Biomedicines | Immunomodulatory Role of Urolithin A on Metabolic Diseases. | 2021 | Details |
| A04307 | 33671547 | Int J Mol Sci | Association of Adipose Tissue and Adipokines with Development of Obesity-Induced Liver Cancer. | 2021 | Details |
| A04315 | 33668153 | Cancers (Basel) | MicroRNA-21 Plays Multiple Oncometabolic Roles in the Process of NAFLD-Related Hepatocellular Carcinoma via PI3K/AKT, TGF-β, and STAT3 Signaling. | 2021 | Details |
| A04320 | 33665859 | J Food Biochem | Protective effects of Dendrobium candidum Wall ex Lindl. on high-fat diet-induced liver damage in mice. | 2021 | Details |
| A04330 | 33664289 | Sci Rep | Clodronate, an inhibitor of the vesicular nucleotide transporter, ameliorates steatohepatitis and acute liver injury. | 2021 | Details |
| A04333 | 33662773 | Clin Res Hepatol Gastroenterol | Low levels of Lysosomal Acid Lipase (LAL) activity increases necroinflammation in adult patients with biopsy-proven metabolic associated fatty liver disease. | 2021 | Details |
| A04345 | 33656663 | Hepatol Int | Gut-liver axis modulation of Panax notoginseng saponins in nonalcoholic fatty liver disease. | 2021 | Details |
| A04356 | 33648923 | Eur Cytokine Netw | Absence of increased liver-related inflammatory markers in type 1 diabetes with metabolic syndrome: a nested case-control study from Brazil. | 2020 | Details |
| A04361 | 33647884 | Aging (Albany NY) | Exercise in mice ameliorates high-fat diet-induced nonalcoholic fatty liver disease by lowering HMGCS2. | 2021 | Details |
| A04362 | 33647823 | Int Immunopharmacol | The SGLT2 inhibitor empagliflozin negatively regulates IL-17/IL-23 axis-mediated inflammatory responses in T2DM with NAFLD via the AMPK/mTOR/autophagy pathway. | 2021 | Details |
| A04364 | 33647584 | Cytokine | Lipid-injured hepatocytes release sOPN to improve macrophage migration via CD44 engagement and pFak-NFκB signaling. | 2021 | Details |
| A04366 | 33647280 | Gastroenterology | Squalene Epoxidase Induces Nonalcoholic Steatohepatitis Via Binding to Carbonic Anhydrase III and is a Therapeutic Target. | 2021 | Details |
| A04370 | 33643422 | Evid Based Complement Alternat Med | Gegen Qinlian Decoction Ameliorates Nonalcoholic Fatty Liver Disease in Rats via Oxidative Stress, Inflammation, and the NLRP3 Signal Axis. | 2021 | Details |
| A04371 | 33643221 | Front Endocrinol (Lausanne) | Sodium-Glucose Co-Transporter 2 Inhibitors for Non-Alcoholic Fatty Liver Disease in Asian Patients With Type 2 Diabetes: A Meta-Analysis. | 2021 | Details |
| A04373 | 33642832 | World J Gastroenterol | Quantitative multiparametric magnetic resonance imaging can aid non-alcoholic steatohepatitis diagnosis in a Japanese cohort. | 2021 | Details |
| A04375 | 33642741 | J Indian Soc Periodontol | Association between nonalcoholic fatty liver disease and inflammatory periodontal disease: A case‑control study. | 2020 | Details |
| A04383 | 33640303 | Dig Liver Dis | Association between the soluble receptor for advanced glycation end products (sRAGE) and NAFLD in participants in the Atherosclerosis Risk in Communities Study. | 2021 | Details |
| A04385 | 33640247 | Phytomedicine | A network pharmacology approach: Inhibition of the NF-κB signaling pathway contributes to the NASH preventative effect of an Oroxylum indicum seed extract in oleic acid-stimulated HepG2 cells and high-fat diet-fed rats. | 2021 | Details |
| A04387 | 33639080 | Int J Med Mushrooms | In Vitro Antioxidation, Antihepatic Steatosis, and Anti-Inflammatory Effects of Ethyl Acetate Fraction from Auricularia nigricans (Agaricomycetes). | 2021 | Details |
| A04395 | 33636024 | Hepatology | Sirtuin 2 Prevents Liver Steatosis and Metabolic Disorders by Deacetylation of Hepatocyte Nuclear Factor 4α. | 2021 | Details |
| A04398 | 33633748 | Front Immunol | Controversies and Opportunities in the Use of Inflammatory Markers for Diagnosis or Risk Prediction in Fatty Liver Disease. | 2021 | Details |
| A04402 | 33632113 | Endocr Metab Immune Disord Drug Targets | Effects of Metformin-Single Therapy on the Level of Inflammatory Markers in Serum of Non-Obese T2DM Patients with NAFLD. | 2022 | Details |
| A04406 | 33630750 | Eur J Endocrinol | MECHANISMS IN ENDOCRINOLOGY: FXR signalling: a novel target in metabolic diseases. | 2021 | Details |
| A04410 | 33629536 | Mol Nutr Food Res | Effect of Mastiha supplementation on NAFLD: The MAST4HEALTH Randomised, Controlled Trial. | 2021 | Details |
| A04412 | 33628758 | Can J Gastroenterol Hepatol | Metabolic and Hepatic Effects of Energy-Reduced Anti-Inflammatory Diet in Younger Adults with Obesity. | 2021 | Details |
| A04413 | 33628620 | Oncoimmunology | Increase of α-dicarbonyls in liver and receptor for advanced glycation end products on immune cells are linked to nonalcoholic fatty liver disease and liver cancer. | 2021 | Details |
| A04419 | 33626003 | Turk J Gastroenterol | Berberine inhibits liver damage in rats with non-alcoholic fatty liver disease by regulating TLR4/MyD88/NF-κB pathway. | 2020 | Details |
| A04424 | 33622003 | Ultraschall Med | Diagnostic Value of Ultrasound in Fatty Liver Disease. | 2021 | Details |
| A04427 | 33619773 | Hepatology | Gene Deconvolution Reveals Aberrant Liver Regeneration and Immune Cell Infiltration in Alcohol-Associated Hepatitis. | 2021 | Details |
| A04428 | 33619282 | Nat Commun | Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation. | 2021 | Details |
| A04444 | 33615164 | ACS Pharmacol Transl Sci | Cytotoxicity, Retention, and Anti-inflammatory Effects of a CeO2 Nanoparticle-Based Supramolecular Complex in a 3D Liver Cell Culture Model. | 2020 | Details |
| A04451 | 33611063 | Int Immunopharmacol | Hyperoside attenuates non-alcoholic fatty liver disease through targeting Nr4A1 in macrophages. | 2021 | Details |
| A04456 | 33609303 | Hepatology | Microbiota-Driven Activation of Intrahepatic B Cells Aggravates NASH Through Innate and Adaptive Signaling. | 2021 | Details |
| A04463 | 33605666 | J Pediatr Gastroenterol Nutr | Severe Acute Respiratory Syndrome Coronavirus-2 Infection in Children With Liver Transplant and Native Liver Disease: An International Observational Registry Study. | 2021 | Details |
| A04464 | 33604259 | J Clin Transl Hepatol | Role of ALDH2 in Hepatic Disorders: Gene Polymorphism and Disease Pathogenesis. | 2021 | Details |
| A04469 | 33603948 | Oxid Med Cell Longev | Bixin Attenuates High-Fat Diet-Caused Liver Steatosis and Inflammatory Injury through Nrf2/PPARα Signals. | 2021 | Details |
| A04472 | 33603757 | Front Immunol | Extracellular Vesicles as Inflammatory Drivers in NAFLD. | 2021 | Details |
| A04474 | 33603666 | Front Pharmacol | The Role of Bone Morphogenetic Protein 9 in Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
| A04482 | 33600604 | J Gastroenterol Hepatol | Visfatin exacerbates hepatic inflammation and fibrosis in a methionine-choline-deficient diet mouse model. | 2021 | Details |
| A04494 | 33596964 | J Med Case Rep | Hemochromatosis, alcoholism and unhealthy dietary fat: a case report. | 2021 | Details |
| A04495 | 33596938 | J Transl Med | Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD. | 2021 | Details |
| A04498 | 33596128 | Arch Physiol Biochem | Folic acid ameliorates palmitate-induced inflammation through decreasing homocysteine and inhibiting NF-κB pathway in HepG2 cells. | 2021 | Details |
| A04502 | 33595214 | Isr Med Assoc J | The Impact of Ramadan Fasting on Fatty Liver Disease Severity: A Retrospective Case Control Study from Israel. | 2021 | Details |
| A04507 | 33594319 | Am J Transl Res | miR-122-5p/KIF5B/AMPK/AKT regulatory network regulates the progression of NAFLD. | 2021 | Details |
| A04537 | 33584555 | Front Microbiol | The Therapeutic Efficacy of Curcumin vs. Metformin in Modulating the Gut Microbiota in NAFLD Rats: A Comparative Study. | 2021 | Details |
| A04538 | 33584545 | Front Endocrinol (Lausanne) | TLR9 in MAFLD and NASH: At the Intersection of Inflammation and Metabolism. | 2021 | Details |
| A04542 | 33584134 | J Med Biochem | The role of oxidative stress in the development of obesity and obesity-related metabolic disorders. | 2021 | Details |
| A04563 | 33579000 | Int J Mol Sci | IL-6 Reduces Mitochondrial Replication, and IL-6 Receptors Reduce Chronic Inflammation in NAFLD and Type 2 Diabetes. | 2021 | Details |
| A04564 | 33578800 | Cancers (Basel) | Inflammatory Mechanisms Underlying Nonalcoholic Steatohepatitis and the Transition to Hepatocellular Carcinoma. | 2021 | Details |
| A04573 | 33576035 | Hepatology | Cordycepin Ameliorates Nonalcoholic Steatohepatitis by Activation of the AMP-Activated Protein Kinase Signaling Pathway. | 2021 | Details |
| A04608 | 33564868 | Am J Clin Nutr | Soft drink consumption and risk of nonalcoholic fatty liver disease: results from the Tianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIH) cohort study. | 2021 | Details |
| A04615 | 33562284 | J Clin Med | Metabolic Imaging in Non-Alcoholic Fatty Liver Disease: Applications of Magnetic Resonance Spectroscopy. | 2021 | Details |
| A04618 | 33561256 | J Nutr | Dietary Fruit and Vegetable Supplementation Suppresses Diet-Induced Atherosclerosis in LDL Receptor Knockout Mice. | 2021 | Details |
| A04628 | 33557653 | Expert Rev Gastroenterol Hepatol | Hepatocyte and immune cell crosstalk in non-alcoholic fatty liver disease. | 2021 | Details |
| A04632 | 33557031 | Life (Basel) | Adiposity in Depression or Depression in Adiposity? The Role of Immune-Inflammatory-Microbial Overlap. | 2021 | Details |
| A04640 | 33554350 | Hepatology | The Clinical Significance of Hepatic CD69+ CD103+ CD8+ Resident-Memory T Cells in Autoimmune Hepatitis. | 2021 | Details |
| A04642 | 33554072 | iScience | Impact of liver-specific GLUT8 silencing on fructose-induced inflammation and omega oxidation. | 2021 | Details |
| A04643 | 33553970 | Hepatol Commun | Human Nonalcoholic Steatohepatitis on a Chip. | 2020 | Details |
| A04650 | 33551355 | Dig Liver Dis | Liver fibrosis in patients with metabolic associated fatty liver disease is a risk factor for adverse outcomes in COVID-19. | 2021 | Details |