Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A31415 | 30621352 | Molecules | Effects of Hydrogen Sulfide on Carbohydrate Metabolism in Obese Type 2 Diabetic Rats. | 2019 | Details |
| A31417 | 30615497 | FASEB J | A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling. | 2019 | Details |
| A31455 | 30523261 | Nat Commun | An inflammatory-CCRK circuitry drives mTORC1-dependent metabolic and immunosuppressive reprogramming in obesity-associated hepatocellular carcinoma. | 2018 | Details |
| A31536 | 30348753 | Pediatrics | Motivational Interviewing to Treat Adolescents With Obesity: A Meta-analysis. | 2018 | Details |
| A31565 | 30283282 | Case Rep Gastroenterol | A Young Adult Patient with Nonalcoholic Steatohepatitis Developed Severe Gastroesophageal Varices Associated with Severe Obesity and Diabetes Mellitus. | 2018 | Details |
| A31583 | 30248539 | Biomed Pharmacother | Effect of silibinin on CFLAR-JNK pathway in oleic acid-treated HepG2 cells. | 2018 | Details |
| A31600 | 30218427 | Dig Dis Sci | PNPLA3 Gene Polymorphisms in HCV/HIV-Coinfected Individuals. | 2018 | Details |
| A31673 | 30057822 | Int J Hepatol | Development of NASH in Obese Mice is Confounded by Adipose Tissue Increase in Inflammatory NOV and Oxidative Stress. | 2018 | Details |
| A31806 | 29780857 | Technology (Singap World Sci) | Multi-omic network-based interrogation of rat liver metabolism following gastric bypass surgery featuring SWATH proteomics. | 2017 | Details |
| A31823 | 29750655 | J Pediatr Endocrinol Metab | Metabolic risk factors in adolescent girls with type 1 diabetes. | 2018 | Details |
| A31886 | 29619418 | Hepatol Commun | The Role of Intestinal C-type Regenerating Islet Derived-3 Lectins for Nonalcoholic Steatohepatitis. | 2018 | Details |
| A31979 | 29404484 | Hepatol Commun | The selective peroxisome proliferator-activated receptor-delta agonist seladelpar reverses nonalcoholic steatohepatitis pathology by abrogating lipotoxicity in diabetic obese mice. | 2017 | Details |
| A31981 | 29404476 | Hepatol Commun | The new-generation pan-peroxisome proliferator-activated receptor agonist IVA337 protects the liver from metabolic disorders and fibrosis. | 2017 | Details |
| A31996 | 29369831 | Curr Opin Lipidol | Novel metabolic phenotypes in lecithin cholesterol acyltyransferase-deficient mice. | 2018 | Details |
| A32019 | 30906835 | Genes Dis | Neonatal overfeeding in mice aggravates the development of methionine and choline-deficient diet-induced steatohepatitis in adulthood. | 2018 | Details |
| A32137 | 29124251 | Hepatol Commun | TRAIL Deletion Prevents Liver, but Not Adipose Tissue, Inflammation during Murine Diet-Induced Obesity. | 2017 | Details |
| A32142 | 29118935 | Gastroenterol Hepatol Bed Bench | A systems biology analysis protein-protein interaction of NASH and IBD based on comprehensive gene information. | 2017 | Details |
| A32173 | 29057935 | Sci Rep | Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice. | 2017 | Details |
| A32178 | 29046730 | Diabetol Metab Syndr | Aliskiren effect on non-alcoholic steatohepatitis in metabolic syndrome. | 2017 | Details |
| A32197 | 28981243 | Rev Med Brux | [Treatments of non-alcoholic steatohepatitis]. | 2019 | Details |
| A32233 | 28912902 | Curr Ther Res Clin Exp | Effects of Dapagliflozin on Body Composition and Liver Tests in Patients with Nonalcoholic Steatohepatitis Associated with Type 2 Diabetes Mellitus: A Prospective, Open-label, Uncontrolled Study. | 2017 | Details |
| A32297 | 28768902 | JCI Insight | Mixed-lineage kinase 3 pharmacological inhibition attenuates murine nonalcoholic steatohepatitis. | 2017 | Details |
| A32341 | 28680450 | Evid Based Complement Alternat Med | An ErChen and YinChen Decoction Ameliorates High-Fat-Induced Nonalcoholic Steatohepatitis in Rats by Regulating JNK1 Signaling Pathway. | 2017 | Details |
| A32348 | 28666011 | PLoS One | Differential effects of Calca-derived peptides in male mice with diet-induced obesity. | 2017 | Details |
| A32362 | 28630652 | Diabetol Metab Syndr | Verification of B-lymphocyte activating factor's involvement in the exacerbation of insulin resistance as well as an autoimmune response in patients with nonalcoholic steatohepatitis and patients with HCV-related chronic liver disease. | 2017 | Details |
| A32449 | 28424556 | Onco Targets Ther | Nonalcoholic steatohepatitis-related hepatocellular carcinoma: is there a role for the androgen receptor pathway? | 2017 | Details |
| A32462 | 28386316 | Am J Transl Res | Energy intake correlates with the levels of fatty acid synthase and insulin-like growth factor-1 in male and female C57BL/6 mice. | 2017 | Details |
| A32493 | 28298638 | Sci Rep | pNaKtide Attenuates Steatohepatitis and Atherosclerosis by Blocking Na/K-ATPase/ROS Amplification in C57Bl6 and ApoE Knockout Mice Fed a Western Diet. | 2017 | Details |
| A32505 | 28255329 | Evid Based Complement Alternat Med | Salidroside Modulates Insulin Signaling in a Rat Model of Nonalcoholic Steatohepatitis. | 2017 | Details |
| A32517 | 28224024 | Gastroenterol Hepatol Bed Bench | Topological and functional analysis of nonalcoholic steatohepatitis through protein interaction mapping. | 2016 | Details |
| A32533 | 28189755 | J Hepatol | Mouse species-specific control of hepatocarcinogenesis and metabolism by FGF19/FGF15. | 2017 | Details |
| A32715 | 27699065 | J Obes | Appetite Suppression and Antiobesity Effect of a Botanical Composition Composed of Morus alba, Yerba mate, and Magnolia officinalis. | 2016 | Details |
| A32871 | 27199763 | Front Physiol | Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation. | 2016 | Details |
| A32879 | 27182456 | J Clin Cell Immunol | Role of Serum Biomarkers in Early Detection of Non-Alcoholic Steatohepatitis and Fibrosis in West Virginian Children. | 2016 | Details |
| A32906 | 27114939 | J Tradit Complement Med | Extract of a polyherbal formulation ameliorates experimental nonalcoholic steatohepatitis. | 2015 | Details |
| A32934 | 27062266 | Hepatol Res | L-carnitine prevents metabolic steatohepatitis in obese diabetic KK-Ay mice. | 2016 | Details |
| A33033 | 26828506 | Int J Environ Res Public Health | Biomarker-Based Approaches for Assessing Alcohol Use Disorders. | 2016 | Details |
| A33056 | 26774017 | Diabetes Metab | Pleiotropic effects of insulin and GLP-1 receptor agonists: Potential benefits of the association. | 2015 | Details |
| A33163 | 26576191 | Evid Based Complement Alternat Med | Berberine Reduces Neurotoxicity Related to Nonalcoholic Steatohepatitis in Rats. | 2015 | Details |
| A33269 | 26330343 | Am J Physiol Endocrinol Metab | Tracer-based assessments of hepatic anaplerotic and TCA cycle flux: practicality, stoichiometry, and hidden assumptions. | 2015 | Details |
| A33270 | 26329544 | Yakugaku Zasshi | [SREBP-1c and Elovl6 as Targets for Obesity-related Disorders]. | 2015 | Details |
| A33285 | 26301053 | World J Hepatol | Recent advances in mouse models of obesity- and nonalcoholic steatohepatitis-associated hepatocarcinogenesis. | 2015 | Details |
| A33388 | 26082668 | Hepat Med | Tyrosine levels are associated with insulin resistance in patients with nonalcoholic fatty liver disease. | 2015 | Details |
| A33441 | 25979814 | Aging (Albany NY) | High-fat diet induced obesity primes inflammation in adipose tissue prior to liver in C57BL/6j mice. | 2015 | Details |
| A33443 | 25977701 | Evid Based Complement Alternat Med | Metabolomics profiling to investigate the pharmacologic mechanisms of berberine for the treatment of high-fat diet-induced nonalcoholic steatohepatitis. | 2015 | Details |
| A33484 | 25903417 | Handb Exp Pharmacol | Immune Cells and Metabolism. | 2016 | Details |
| A33490 | 25888330 | Gastroenterology | Hepatocyte Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 4 Regulates Stress Signaling, Fibrosis, and Insulin Sensitivity During Development of Steatohepatitis in Mice. | 2015 | Details |
| A33517 | 25826083 | Oncotarget | PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis. | 2015 | Details |
| A33635 | 25548285 | J Biol Chem | Free fatty acids shift insulin-induced hepatocyte proliferation towards CD95-dependent apoptosis. | 2014 | Details |
| A33687 | 25412903 | J Viral Hepat | Oral anti-CD3 immunotherapy for HCV-nonresponders is safe, promotes regulatory T cells and decreases viral load and liver enzyme levels: results of a phase-2a placebo-controlled trial. | 2014 | Details |
| A33696 | 25385666 | Ir J Med Sci | Liver injury attenuation by curcumin in a rat NASH model: an Nrf2 activation-mediated effect? | 2014 | Details |
| A33735 | 25279794 | Endocrinology | Osteocalcin protects against nonalcoholic steatohepatitis in a mouse model of metabolic syndrome. | 2014 | Details |
| A33799 | 25132496 | Cancer Cell | ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development. | 2014 | Details |
| A33828 | 25066692 | Gastroenterology | Roles for chemokines in liver disease. | 2014 | Details |
| A33907 | 24910242 | Cell Metab | Liver damage, inflammation, and enhanced tumorigenesis after persistent mTORC1 inhibition. | 2014 | Details |
| A33966 | 24763197 | Exp Mol Med | Oleuropein prevents the progression of steatohepatitis to hepatic fibrosis induced by a high-fat diet in mice. | 2014 | Details |
| A34076 | 24471744 | J Pharm Pharmacol | Bupropion effects on high-fat diet-induced steatohepatitis and endothelial dysfunction in rats: role of tumour necrosis factor-alpha. | 2014 | Details |
| A34109 | 27433515 | Int Sch Res Notices | Serological and Histological Examination of a Nonalcoholic Steatohepatitis Mouse Model Created via the Administration of Monosodium Glutamate. | 2014 | Details |
| A34154 | 24303091 | World J Hepatol | Increased bone mineral density in patients with non-alcoholic steatohepatitis. | 2013 | Details |
| A34156 | 26202298 | Hepatol Int | Pharmacological agents for nonalcoholic steatohepatitis. | 2013 | Details |
| A34157 | 26202296 | Hepatol Int | Insulin resistance: mechanism and implications for carcinogenesis and hepatocellular carcinoma in NASH. | 2013 | Details |
| A34199 | 24145238 | Lab Invest | A novel mouse model of nonalcoholic steatohepatitis with significant insulin resistance. | 2013 | Details |
| A34217 | 24065439 | Obes Surg | Genetic risk score does not predict the outcome of obesity surgery. | 2014 | Details |
| A34223 | 24045151 | J Hepatol | A phase II study of cixutumumab (IMC-A12, NSC742460) in advanced hepatocellular carcinoma. | 2013 | Details |
| A34295 | 23832448 | Hepatology | Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice. | 2013 | Details |
| A34296 | 23828575 | Cell Death Dis | Diabetic liver injury from streptozotocin is regulated through the caspase-8 homolog cFLIP involving activation of JNK2 and intrahepatic immunocompetent cells. | 2013 | Details |
| A34334 | 26201790 | Hepatol Int | The influence of pioglitazone on the plasma amino acid profile in patients with nonalcoholic steatohepatitis (NASH). | 2012 | Details |
| A34335 | 26201785 | Hepatol Int | B cell-activating factor is associated with the histological severity of nonalcoholic fatty liver disease. | 2012 | Details |
| A34488 | 23337159 | Endocr Pract | Bone mineral density in patients with nonalcoholic steatohepatitis among end-stage liver disease patients awaiting liver transplantation. | 2014 | Details |
| A34504 | 23294302 | J Toxicol Environ Health A | Polybrominated diphenyl ethers alter hepatic phosphoenolpyruvate carboxykinase enzyme kinetics in male Wistar rats: implications for lipid and glucose metabolism. | 2013 | Details |
| A34505 | 23293533 | J Inflamm Res | Alleviation of insulin resistance and liver damage by oral administration of Imm124-E is mediated by increased Tregs and associated with increased serum GLP-1 and adiponectin: results of a phase I/II clinical trial in NASH. | 2012 | Details |
| A34512 | 23275357 | Diabetes Care | The association between hepatic fat content and liver injury in obese children and adolescents: effects of ethnicity, insulin resistance, and common gene variants. | 2012 | Details |
| A34514 | 27335818 | ISRN Hepatol | Murine Models of Nonalcoholic Fatty Liver Disease and Steatohepatitis. | 2012 | Details |
| A34545 | 23233000 | Surg Endosc | Resistin expression correlates with steatohepatitis in morbidly obese patients. | 2012 | Details |
| A34549 | 23227320 | Hepat Res Treat | Antioxidant therapy in nonalcoholic steatohepatitis. | 2012 | Details |
| A34552 | 23219586 | Metabolism | A case report and review of the literature of laparoscopic sleeve gastrectomy in morbidly obese adolescents: beyond metabolic surgery and visceral fat reduction. | 2012 | Details |
| A34581 | 23149694 | Genes Nutr | Time-dependent network analysis reveals molecular targets underlying the development of diet-induced obesity and non-alcoholic steatohepatitis. | 2012 | Details |
| A34583 | 23147115 | Int J Obes (Lond) | Increased insulin receptor substrate 2 expression is associated with steatohepatitis and altered lipid metabolism in obese subjects. | 2012 | Details |
| A34615 | 23056165 | PLoS One | Correction of liver steatosis by a hydrophobic iminosugar modulating glycosphingolipids metabolism. | 2012 | Details |
| A34631 | 23029000 | PLoS One | VSL#3 resets insulin signaling and protects against NASH and atherosclerosis in a model of genetic dyslipidemia and intestinal inflammation. | 2012 | Details |
| A34657 | 22977616 | Exp Ther Med | Adiponectin suppresses endoplasmic reticulum stress in nonalcoholic steatohepatitis. | 2011 | Details |
| A34667 | 22954163 | J Sch Health | Evaluation of the impact of a diabetes education curriculum for school personnel on disease knowledge and confidence in caring for students. | 2012 | Details |
| A34685 | 22882855 | Chin Med J (Engl) | Pioglitazone ameliorates nonalcoholic steatohepatitis by down-regulating hepatic nuclear factor-kappa B and cyclooxygenases-2 expression in rats. | 2012 | Details |
| A34698 | 22846857 | Semin Oncol | Surveillance for hepatocellular carcinoma. | 2012 | Details |
| A34711 | 22804755 | J Pineal Res | Plasma insulin, leptin, adiponectin, resistin, ghrelin, and melatonin in nonalcoholic steatohepatitis patients treated with melatonin. | 2012 | Details |
| A34756 | 22690069 | World J Gastroenterol | Leaky gut and the liver: a role for bacterial translocation in nonalcoholic steatohepatitis. | 2012 | Details |
| A34846 | 22442158 | Am J Physiol Gastrointest Liver Physiol | Hepatic recruitment of macrophages promotes nonalcoholic steatohepatitis through CCR2. | 2012 | Details |
| A34925 | 24829630 | Middle East J Dig Dis | Metformin in nonalcoholic steatohepatitis: a randomized controlled trial. | 2012 | Details |
| A35001 | 22013536 | Int J Hepatol | NCX 1000 Alone or in Combination with Vitamin E Reverses Experimental Nonalcoholic Steatohepatitis in the Rat Similarly to UDCA. | 2011 | Details |
| A35022 | 21933146 | Curr Pharm Des | Metabolic therapy: lessons from liver diseases. | 2011 | Details |
| A35029 | 21922031 | Therap Adv Gastroenterol | Glitazones for human nonalcoholic steatohepatitis. | 2011 | Details |
| A35052 | 21865331 | Am J Clin Nutr | Effect of lectin-like oxidized LDL receptor-1 polymorphism on liver disease, glucose homeostasis, and postprandial lipoprotein metabolism in nonalcoholic steatohepatitis. | 2011 | Details |
| A35053 | 21865094 | Surg Obes Relat Dis | Serologic predictors of nonalcoholic steatohepatitis in a population undergoing bariatric surgery. | 2011 | Details |
| A35059 | 21845516 | J Clin Immunol | Altered phenotype and functionality of circulating immune cells characterize adult patients with nonalcoholic steatohepatitis. | 2011 | Details |
| A35111 | 21711428 | Hepatol Res | Pharmacological therapy for non-alcoholic steatohepatitis: How efficient are thiazolidinediones? | 2011 | Details |
| A35113 | 21711424 | Hepatol Res | Ursodeoxycholic acid dose-dependently improves liver injury in rats fed a methionine- and choline-deficient diet. | 2011 | Details |
| A35124 | 21689613 | Clin Liver Dis | Insulin resistance and other metabolic risk factors in the pathogenesis of hepatocellular carcinoma. | 2011 | Details |
| A35179 | 21519329 | Lab Invest | Oncostatin M produced in Kupffer cells in response to PGE2: possible contributor to hepatic insulin resistance and steatosis. | 2011 | Details |
| A35205 | 21448070 | Eur J Gastroenterol Hepatol | Elevated hepatic fatty acid oxidation, high plasma fibroblast growth factor 21, and fasting bile acids in nonalcoholic steatohepatitis. | 2011 | Details |
| A35249 | 21299162 | Acta Gastroenterol Belg | Why should the gastroenterologist bother about obesity? An oncologic point of view. | 2011 | Details |