Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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40433 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A08097 | 32246876 | J Gastroenterol Hepatol | Development and validation of a novel non-invasive test for diagnosing fibrotic non-alcoholic steatohepatitis in patients with biopsy-proven non-alcoholic fatty liver disease. | 2020 | Details |
| A08098 | 32245940 | Med Sci Monit | Ganoderma Lucidum Polysaccharides Ameliorates Hepatic Steatosis and Oxidative Stress in db/db Mice via Targeting Nuclear Factor E2 (Erythroid-Derived 2)-Related Factor-2/Heme Oxygenase-1 (HO-1) Pathway. | 2020 | Details |
| A08100 | 32245619 | Biochem Biophys Res Commun | Humanin attenuates palmitate-induced hepatic lipid accumulation and insulin resistance via AMPK-mediated suppression of the mTOR pathway. | 2020 | Details |
| A08101 | 32245586 | Chin J Nat Med | Selenium-enriched Bifidobacterium longum protected alcohol and high fat diet induced hepatic injury in mice. | 2020 | Details |
| A08102 | 32245585 | Chin J Nat Med | Fatty liver diseases, mechanisms, and potential therapeutic plant medicines. | 2020 | Details |
| A08103 | 32245414 | BMC Gastroenterol | Incidence, aetiology and related comorbidities of cirrhosis: a Swedish population-based cohort study. | 2020 | Details |
| A08104 | 32245205 | Int J Mol Sci | Combined Treatment with Sodium-Glucose Cotransporter-2 Inhibitor (Canagliflozin) and Dipeptidyl Peptidase-4 Inhibitor (Teneligliptin) Alleviates NASH Progression in A Non-Diabetic Rat Model of Steatohepatitis. | 2020 | Details |
| A08105 | 32245128 | Nutrients | Increase of Akkermansia muciniphila by a Diet Containing Japanese Traditional Medicine Bofutsushosan in a Mouse Model of Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A08106 | 32244908 | Nutrients | Dietary Factors in Relation to Liver Fat Content: A Cross-sectional Study. | 2020 | Details |
| A08107 | 32244304 | Cells | Role and Mechanisms of Mitophagy in Liver Diseases. | 2020 | Details |
| A08108 | 32244266 | Int J Mol Sci | Hepatic Lipid Catabolism via PPARα-Lysosomal Crosstalk. | 2020 | Details |
| A08109 | 32244182 | Mol Metab | Impact of global PTP1B deficiency on the gut barrier permeability during NASH in mice. | 2020 | Details |
| A08110 | 32243868 | Metabolism | Myeloid-specific IRE1alpha deletion reduces tumour development in a diabetic, non-alcoholic steatohepatitis-induced hepatocellular carcinoma mouse model. | 2020 | Details |
| A08111 | 32243703 | Liver Int | Bile acids associate with specific gut microbiota, low-level alcohol consumption and liver fibrosis in patients with non-alcoholic fatty liver disease. | 2020 | Details |
| A08112 | 32243369 | Medicine (Baltimore) | Association of resting heart rate with nonalcoholic fatty liver disease in postmenopausal women. | 2020 | Details |
| A08113 | 32243137 | Bioconjug Chem | New Generation Oxyntomodulin Peptides with Improved Pharmacokinetic Profiles Exhibit Weight Reducing and Anti-Steatotic Properties in Mice. | 2020 | Details |
| A08114 | 32242391 | J Tradit Chin Med | Sini powder ameliorates the inflammatory response in rats with stress-induced non-alcoholic fatty liver disease by inhibiting the nuclear factor kappa-B / pyrin domain-containing protein 3 pathway. | 2020 | Details |
| A08115 | 32241197 | Expert Rev Gastroenterol Hepatol | Obeticholic acid for the treatment of nonalcoholic steatohepatitis. | 2020 | Details |
| A08116 | 32240928 | Phytomedicine | Phytotherapy using blueberry leaf polyphenols to alleviate non-alcoholic fatty liver disease through improving mitochondrial function and oxidative defense. | 2020 | Details |
| A08117 | 32240838 | Atherosclerosis | Association between liver fibrosis scores and the risk of mortality among patients with coronary artery disease. | 2020 | Details |
| A08118 | 32240717 | J Hepatol | Changes in frailty are associated with waitlist mortality in patients with cirrhosis. | 2020 | Details |
| A08119 | 32240652 | Biochem Pharmacol | Pyrvinium pamoate attenuates non-alcoholic steatohepatitis: Insight on hedgehog/Gli and Wnt/β-catenin signaling crosstalk. | 2020 | Details |
| A08120 | 32240015 | J Appl Physiol (1985) | Sex and BNIP3 genotype, rather than acute lipid injection, modulate hepatic mitochondrial function and steatosis risk in mice. | 2020 | Details |
| A08122 | 32239453 | Endocrine | Insulin resistance is related with liver fibrosis in type 2 diabetic patients with non-alcoholic fatty liver disease proven biopsy and Mediterranean diet pattern as a protective factor. | 2020 | Details |
| A08123 | 32239376 | Dig Dis Sci | Exercise Attenuates Ribosomal Protein Six Phosphorylation in Fatty Liver Disease. | 2020 | Details |
| A08124 | 32239220 | JAMA Netw Open | Trends in the Burden of Chronic Liver Disease Among Hospitalized US Adults. | 2020 | Details |
| A08125 | 32239031 | Chem Commun (Camb) | Simultaneous co-assembly of fenofibrate and ketoprofen peptide for the dual-targeted treatment of nonalcoholic fatty liver disease (NAFLD). | 2020 | Details |
| A08126 | 32238704 | Biol Pharm Bull | Reduced Serum Cholesterol and Triglyceride Levels in a Choline-Deficient L-Amino Acid-Defined High-Fat Diet (CDAHFD)-Induced Mouse Model of Non-alcoholic Steatohepatitis (NASH). | 2020 | Details |
| A08127 | 32237922 | Int J Food Sci Nutr | Combined cranberry supplementation and weight loss diet in non-alcoholic fatty liver disease: a double-blind placebo-controlled randomized clinical trial. | 2020 | Details |
| A08128 | 32237916 | Expert Opin Pharmacother | Current and new pharmacotherapy options for non-alcoholic steatohepatitis. | 2020 | Details |
| A08129 | 32237015 | Pediatr Diabetes | Associations of physical activity and fitness with hepatic steatosis, liver enzymes, and insulin resistance in children with overweight/obesity. | 2020 | Details |
| A08130 | 32235829 | Cell Death Dis | TNF-Receptor-1 inhibition reduces liver steatosis, hepatocellular injury and fibrosis in NAFLD mice. | 2020 | Details |
| A08131 | 32235813 | J Clin Med | Emergent Properties of the HNF4α-PPARγ Network May Drive Consequent Phenotypic Plasticity in NAFLD. | 2020 | Details |
| A08132 | 32235601 | J Clin Med | Active Helicobacter pylori Infection is Independently Associated with Nonalcoholic Steatohepatitis in Morbidly Obese Patients. | 2020 | Details |
| A08133 | 32235497 | Nutrients | Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A08134 | 32235172 | J Acquir Immune Defic Syndr | Brief Report: Relationship Between Nonalcoholic Fatty Liver Disease and Cardiovascular Disease in Persons With HIV. | 2020 | Details |
| A08135 | 32234329 | J Hepatol | Volixibat in adults with non-alcoholic steatohepatitis: 24-week interim analysis from a randomized, phase II study. | 2020 | Details |
| A08136 | 32232972 | J Diabetes Investig | New perspective on type 2 diabetes, dyslipidemia and non-alcoholic fatty liver disease. | 2020 | Details |
| A08137 | 32231898 | Cureus | Accuracy of Multi-echo Dixon Sequence in Quantification of Hepatic Steatosis. | 2020 | Details |
| A08138 | 32231762 | World J Hepatol | High omega arachidonic acid/docosahexaenoic acid ratio induces mitochondrial dysfunction and altered lipid metabolism in human hepatoma cells. | 2020 | Details |
| A08139 | 32231442 | Clin Med Insights Endocrinol Diabetes | Dipeptidyl Peptidase-4 at the Interface Between Inflammation and Metabolism. | 2020 | Details |
| A08140 | 32231437 | Diabetes Metab Syndr Obes | Dual SGLT1/SGLT2 Inhibitor Phlorizin Ameliorates Non-Alcoholic Fatty Liver Disease and Hepatic Glucose Production in Type 2 Diabetic Mice. | 2020 | Details |
| A08141 | 32231050 | Nutrients | Celiac Disease, Gluten-Free Diet, and Metabolic and Liver Disorders. | 2020 | Details |
| A08142 | 32231001 | Cells | Extracellular Vesicles in NAFLD/ALD: From Pathobiology to Therapy. | 2020 | Details |
| A08143 | 32230987 | Nutrients | Randomised Double-Blind Placebo-Controlled Trial of Inulin with Metronidazole in Non-Alcoholic Fatty Liver Disease (NAFLD). | 2020 | Details |
| A08144 | 32230953 | Nutrients | Inflammation in Primary and Metastatic Liver Tumorigenesis-Under the Influence of Alcohol and High-Fat Diets. | 2020 | Details |
| A08145 | 32229588 | J Lipid Res | The lncRNA Gm15622 stimulates SREBP-1c expression and hepatic lipid accumulation by sponging the miR-742-3p in mice. | 2020 | Details |
| A08148 | 32228845 | Med Sci (Paris) | [Emergence of 3D human fatty liver models engineered in the laboratory]. | 2020 | Details |
| A08149 | 32228319 | Am J Physiol Endocrinol Metab | Downregulated microRNA-130b-5p prevents lipid accumulation and insulin resistance in a murine model of nonalcoholic fatty liver disease. | 2020 | Details |
| A08150 | 32228300 | Gut Microbes | Maternal sucralose intake alters gut microbiota of offspring and exacerbates hepatic steatosis in adulthood. | 2020 | Details |
| A08151 | 32226996 | Food Funct | The protective mechanism of Lactobacillus plantarum FZU3013 against non-alcoholic fatty liver associated with hyperlipidemia in mice fed a high-fat diet. | 2020 | Details |
| A08152 | 32226553 | Theranostics | Quantitative ultrasound approaches for diagnosis and monitoring hepatic steatosis in nonalcoholic fatty liver disease. | 2020 | Details |
| A08153 | 32226411 | Front Endocrinol (Lausanne) | Women Are at a Higher Risk of Chronic Metabolic Diseases Compared to Men With Increasing Body Mass Index in China. | 2020 | Details |
| A08154 | 32225165 | J Vis Exp | Murine Precision-Cut Liver Slices as an Ex Vivo Model of Liver Biology. | 2020 | Details |
| A08155 | 32225108 | Int J Mol Sci | Targeting of Secretory Proteins as a Therapeutic Strategy for Treatment of Nonalcoholic Steatohepatitis (NASH). | 2020 | Details |
| A08156 | 32224733 | Ann Surg | Bariatric Surgery is Associated With Decreased Progression of Nonalcoholic Fatty Liver Disease to Cirrhosis: A Retrospective Cohort Analysis. | 2020 | Details |
| A08157 | 32223926 | Biochem Biophys Res Commun | Remdesivir attenuates high fat diet (HFD)-induced NAFLD by regulating hepatocyte dyslipidemia and inflammation via the suppression of STING. | 2020 | Details |
| A08158 | 32223569 | Arch Physiol Biochem | Crosstalk between kidney and liver in non-alcoholic fatty liver disease: mechanisms and therapeutic approaches. | 2020 | Details |
| A08159 | 32223545 | Paediatr Int Child Health | The change in prevalence of suspected non-alcoholic fatty liver disease in Korean adolescents from 2001 to 2017. | 2020 | Details |
| A08160 | 34908794 | Ayu | Efficacy of Sharapunkhadi powder (a polyherbal formulation) and lifestyle modification in the management of nonalcoholic fatty liver disease-A randomized placebo-controlled clinical trial. | 2021 | Details |
| A08162 | 32222944 | Indian J Gastroenterol | Correlation between insulin resistance and liver histology in patients with nonalcoholic steatohepatitis with and without obesity. | 2020 | Details |
| A08163 | 32222873 | Glycoconj J | Disruption of hepatocyte Sialylation drives a T cell-dependent pro-inflammatory immune tone. | 2020 | Details |
| A08165 | 32220662 | Atherosclerosis | Relationship of fibroblast growth factor 21 levels with inflammation, lipoproteins and non-alcoholic fatty liver disease. | 2020 | Details |
| A08166 | 32220583 | J Hepatol | MLKL-dependent signaling regulates autophagic flux in a murine model of non-alcohol-associated fatty liver and steatohepatitis. | 2020 | Details |
| A08168 | 32220085 | J Gastroenterol Hepatol | PNPLA3 gene polymorphism and overall and cardiovascular mortality in the United States. | 2020 | Details |
| A08169 | 32220030 | J Biochem Mol Toxicol | Chrysin ameliorates hepatic steatosis induced by a diet deficient in methionine and choline by inducing the secretion of hepatocyte nuclear factor 4α-dependent very low-density lipoprotein. | 2020 | Details |
| A08171 | 32219261 | Food Funct | The protective mechanisms of macroalgae Laminaria japonica consumption against lipid metabolism disorders in high-fat diet-induced hyperlipidemic rats. | 2020 | Details |
| A08173 | 32218743 | Front Physiol | Protective Properties of FOXO1 Inhibition in a Murine Model of Non-alcoholic Fatty Liver Disease Are Associated With Attenuation of ER Stress and Necroptosis. | 2020 | Details |
| A08174 | 32218179 | Biomolecules | A Sweet Connection? Fructose's Role in Hepatocellular Carcinoma. | 2020 | Details |
| A08175 | 32218121 | Nutrients | Negative Energy Balance Induced by Exercise or Diet: Effects on Visceral Adipose Tissue and Liver Fat. | 2020 | Details |
| A08176 | 32217808 | J Endocrinol | Hepatic inflammation precedes steatosis and is mediated by visceral fat accumulation. | 2020 | Details |
| A08177 | 32217639 | Gut | Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinoma. | 2020 | Details |
| A08178 | 32217466 | J Nutr Biochem | The modulation of Luffa cylindrica (L.) Roem supplementation on gene expression and amino acid profiles in liver for alleviating hepatic steatosis via gut microbiota in high-fat diet-fed mice: insight from hepatic transcriptome analysis. | 2020 | Details |
| A08179 | 32217148 | Pharmacol Res | Oleoylethanolamide supplementation in obese patients newly diagnosed with non-alcoholic fatty liver disease: Effects on metabolic parameters, anthropometric indices, and expression of PPAR-α, UCP1, and UCP2 genes. | 2020 | Details |
| A08180 | 32217109 | Chem Biol Interact | Familial non-alcoholic steatohepatitis leading to hepatocellular carcinoma. | 2020 | Details |
| A08181 | 32217100 | Biochem Pharmacol | Modulation of SIRT1-mediated signaling cascades in the liver contributes to the amelioration of nonalcoholic steatohepatitis in high fat fed middle-aged LDL receptor knockout mice by dihydromyricetin. | 2020 | Details |
| A08182 | 32216563 | Cancer Control | High Squalene Epoxidase in Tumors Predicts Worse Survival in Patients With Hepatocellular Carcinoma: Integrated Bioinformatic Analysis on NAFLD and HCC. | 2020 | Details |
| A08183 | 32216545 | Tissue Eng Part B Rev | Fat-On-A-Chip Models for Research and Discovery in Obesity and Its Metabolic Comorbidities. | 2020 | Details |
| A08184 | 32216182 | Rev Med Suisse | [New trends in non-alcoholic fatty liver diseases (NAFLD)]. | 2020 | Details |
| A08185 | 32215009 | Int J Endocrinol | The Dose-Response Relationship between Gamma-Glutamyl Transferase and Risk of Diabetes Mellitus Using Publicly Available Data: A Longitudinal Study in Japan. | 2020 | Details |
| A08186 | 32214246 | Nature | Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. | 2020 | Details |
| A08187 | 32213734 | Endocr J | The risk factors for hepatic steatosis in patients with primary aldosteronism. | 2020 | Details |
| A08188 | 32213662 | Aging (Albany NY) | Role of mitochondrial quality control in the pathogenesis of nonalcoholic fatty liver disease. | 2020 | Details |
| A08189 | 32213035 | United European Gastroenterol J | Clinical management of type C hepatic encephalopathy. | 2020 | Details |
| A08190 | 32213023 | United European Gastroenterol J | Novel reliability criteria for controlled attenuation parameter assessments for non-invasive evaluation of hepatic steatosis. | 2020 | Details |
| A08191 | 32212870 | Expert Rev Endocrinol Metab | Nonalcoholic fatty liver disease, insulin resistance, and sweeteners: a literature review. | 2020 | Details |
| A08192 | 32212193 | Cell Biochem Funct | Knockdown of long non-coding RNA Gm10804 suppresses disorders of hepatic glucose and lipid metabolism in diabetes with non-alcoholic fatty liver disease. | 2020 | Details |
| A08193 | 32211410 | Front Cell Dev Biol | Involvement of Nucleotide-Binding Oligomerization Domain-Like Receptor Family Pyrin Domain Containing 3 Inflammasome in the Pathogenesis of Liver Diseases. | 2020 | Details |
| A08194 | 32211252 | Cureus | Anthropometric Measurements and Lifestyle Characteristics of Individuals with Non-alcoholic Fatty Liver Disease. | 2020 | Details |
| A08195 | 32210914 | Front Endocrinol (Lausanne) | The Atypical Cannabinoid Abn-CBD Reduces Inflammation and Protects Liver, Pancreas, and Adipose Tissue in a Mouse Model of Prediabetes and Non-alcoholic Fatty Liver Disease. | 2020 | Details |
| A08196 | 32210812 | Front Pharmacol | Hepatic Proteomic Changes and Sirt1/AMPK Signaling Activation by Oxymatrine Treatment in Rats With Non-alcoholic Steatosis. | 2020 | Details |
| A08197 | 32209476 | Cell Rep | OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation. | 2020 | Details |
| A08198 | 32209063 | BMC Public Health | Height predict incident non-alcoholic fatty liver disease among general adult population in Tianjin, China, independent of body mass index, waist circumference, waist-to-height ratio, and metabolic syndrome. | 2020 | Details |
| A08199 | 32208163 | Comput Biol Chem | Network pharmacology analysis of Chaihu Lizhong Tang treating non-alcoholic fatty liver disease. | 2020 | Details |
| A08200 | 32207804 | JAMA | Nonalcoholic Steatohepatitis: A Review. | 2020 | Details |
| A08201 | 32207583 | Adv Clin Exp Med | Advanced glycation end products derived from serum albumin modification by glucose (AGE-1) reflect clustering of lipid-associated metabolic abnormalities and are decreased in patients treated with acarbose: A cross-sectional study. | 2020 | Details |
| A08202 | 32207277 | Endocrinol Metab (Seoul) | Visceral-to-Subcutaneous Abdominal Fat Ratio Is Associated with Nonalcoholic Fatty Liver Disease and Liver Fibrosis. | 2020 | Details |
| A08203 | 32207258 | Endocrinol Metab (Seoul) | Impact of Skeletal Muscle Mass on Metabolic Health. | 2020 | Details |
| A08204 | 32207237 | Obes Rev | Beneficial effects of the ketogenic diet on nonalcoholic fatty liver disease: A comprehensive review of the literature. | 2020 | Details |
| A08205 | 32205994 | World J Gastroenterol | Mesencephalic astrocyte-derived neurotrophic factor ameliorates steatosis in HepG2 cells by regulating hepatic lipid metabolism. | 2020 | Details |