Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A29602 | 33813074 | Clin Gastroenterol Hepatol | Association of Weight Changes With Changes in Histological Features and Blood Markers in Nonalcoholic Steatohepatitis. | 2021 | Details |
| A29609 | 33802238 | Cancers (Basel) | Cache Domain Containing 1 Is a Novel Marker of Non-Alcoholic Steatohepatitis-Associated Hepatocarcinogenesis. | 2021 | Details |
| A29616 | 33796224 | Oncotarget | Characterization of the inflammatory microenvironment and hepatic macrophage subsets in experimental hepatocellular carcinoma models. | 2021 | Details |
| A29647 | 33746444 | J Clin Exp Hepatol | Higher Levels of Fibrosis in a Cohort of Veterans with Chronic Viral Hepatitis are Associated with Extrahepatic Cancers. | 2020 | Details |
| A29659 | 33729641 | J Biochem Mol Toxicol | Differentially expressed proteins obtained by label-free quantitative proteomic analysis reveal affected biological processes and functions in Western diet-induced steatohepatitis. | 2021 | Details |
| A29736 | 33604255 | J Clin Transl Hepatol | New Drugs on the Block-Emerging Treatments for Nonalcoholic Steatohepatitis. | 2020 | Details |
| A29738 | 33596344 | Hepatol Res | Abnormal fucosylation of alpha-fetoprotein in patients with nonalcoholic steatohepatitis. | 2021 | Details |
| A29750 | 33574830 | Front Genet | Downregulated microRNA-129-5p by Long Non-coding RNA NEAT1 Upregulates PEG3 Expression to Aggravate Non-alcoholic Steatohepatitis. | 2021 | Details |
| A29753 | 33564498 | Cureus | A Review of Pirfenidone as an Anti-Fibrotic in Idiopathic Pulmonary Fibrosis and Its Probable Role in Other Diseases. | 2021 | Details |
| A29786 | 33521599 | iScience | Iron-rich Kupffer cells exhibit phenotypic changes during the development of liver fibrosis in NASH. | 2021 | Details |
| A29803 | 33490302 | ACG Case Rep J | Intragastric Balloon Improves Steatohepatitis and Fibrosis. | 2021 | Details |
| A29820 | 33447518 | J Clin Transl Hepatol | A 3D Human Liver Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A29845 | 33411729 | PLoS One | Liver stiffness measured by two-dimensional shear-wave elastography predicts hepatic vein pressure gradient at high values in liver transplant candidates with advanced liver cirrhosis. | 2021 | Details |
| A29855 | 33390537 | Biol Pharm Bull | Suppression of Hepatic Stellate Cell Death by Toxic Advanced Glycation End-Products. | 2021 | Details |
| A29919 | 33277568 | Sci Rep | Discovery of a novel fibroblast activation protein (FAP) inhibitor, BR103354, with anti-diabetic and anti-steatotic effects. | 2020 | Details |
| A29923 | 33268008 | Bioorg Chem | Discovery of a novel GLP-1/GIP dual receptor agonist CY-5 as long-acting hypoglycemic, anti-obesity agent. | 2020 | Details |
| A29930 | 33255794 | J Clin Med | Risk Factors, Pathogenesis, and Strategies for Hepatocellular Carcinoma Prevention: Emphasis on Secondary Prevention and Its Translational Challenges. | 2020 | Details |
| A29933 | 33251276 | Visc Med | Emerging Pharmacological Treatment in Nonalcoholic Steatohepatitis. | 2020 | Details |
| A29936 | 33247991 | Hepatol Res | Angiopoietin-like protein 4 deficiency augments liver fibrosis in liver diseases such as nonalcoholic steatohepatitis in mice through enhanced free cholesterol accumulation in hepatic stellate cells. | 2021 | Details |
| A29943 | 33225916 | BMC Cancer | Hepatocellular carcinoma: Intratumoral EpCAM-positive cancer stem cell heterogeneity identifies high-risk tumor subtype. | 2020 | Details |
| A29963 | 33198153 | Biology (Basel) | Emerging Roles of Liver Sinusoidal Endothelial Cells in Nonalcoholic Steatohepatitis. | 2020 | Details |
| A29976 | 33178326 | Evid Based Complement Alternat Med | Efficacy and Mechanism of a Chinese Classic Prescription of Yueju in Treating Nonalcoholic Steatohepatitis and Protecting Hepatocytes from Apoptosis. | 2020 | Details |
| A29985 | 33163834 | Hepatol Commun | Fatigue and Pruritus in Patients with Advanced Fibrosis Due to Nonalcoholic Steatohepatitis: The Impact on Patient-Reported Outcomes. | 2020 | Details |
| A30071 | 33024711 | MethodsX | Flow cytometric quantification of neutral lipids in a human skin stem cell-derived model of NASH. | 2020 | Details |
| A30130 | 32937969 | Biomedicines | Mitochondrial Transfer by Human Mesenchymal Stromal Cells Ameliorates Hepatocyte Lipid Load in a Mouse Model of NASH. | 2020 | Details |
| A30134 | 32923834 | Hepatol Commun | The Selective Peroxisome Proliferator-Activated Receptor Gamma Modulator CHS-131 Improves Liver Histopathology and Metabolism in a Mouse Model of Obesity and Nonalcoholic Steatohepatitis. | 2020 | Details |
| A30155 | 32884369 | Hepat Med | Evaluating the Therapeutic Potential of Cenicriviroc in the Treatment of Nonalcoholic Steatohepatitis with Fibrosis: A Brief Report on Emerging Data. | 2020 | Details |
| A30156 | 32882802 | Antioxidants (Basel) | Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation. | 2020 | Details |
| A30198 | 32833150 | Ann Surg Oncol | The Impact of Modern Chemotherapy and Chemotherapy-Associated Liver Injuries (CALI) on Liver Function: Value of 99mTc-Labelled-Mebrofenin SPECT-Hepatobiliary Scintigraphy. | 2020 | Details |
| A30219 | 32793866 | Mayo Clin Proc Innov Qual Outcomes | Hepatitis C Testing and Liver Fibrosis Predictors in the Birth Cohort of a Primary Care Practice. | 2020 | Details |
| A30235 | 32768645 | Bioorg Med Chem Lett | Selective thyroid hormone receptor β agonists with oxadiazolone acid isosteres. | 2020 | Details |
| A30237 | 32764725 | Nat Rev Endocrinol | The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic. | 2020 | Details |
| A30256 | 32733451 | Front Immunol | The Role of Macrophage-Inducible C-Type Lectin in Different Stages of Chronic Liver Disease. | 2020 | Details |
| A30280 | 32705539 | J Cell Commun Signal | Et tu, CCN1…. | 2020 | Details |
| A30319 | 32650615 | Biology (Basel) | Role of B Cell Lymphoma 2 in the Regulation of Liver Fibrosis in miR-122 Knockout Mice. | 2020 | Details |
| A30324 | 32645655 | J Nutr Biochem | The deficit in folate and vitamin B12 triggers liver macrovesicular steatosis and inflammation in rats with dextran sodium sulfate-induced colitis. | 2020 | Details |
| A30344 | 32612285 | Lab Invest | Cholestasis impairs hepatic lipid storage via AMPK and CREB signaling in hepatitis B virus surface protein transgenic mice. | 2020 | Details |
| A30360 | 32575352 | Microorganisms | Bile Acid Sequestrant, Sevelamer Ameliorates Hepatic Fibrosis with Reduced Overload of Endogenous Lipopolysaccharide in Experimental Nonalcoholic Steatohepatitis. | 2020 | Details |
| A30383 | 32530750 | Hum Vaccin Immunother | Different roles of interleukin 6 and interleukin 11 in the liver: implications for therapy. | 2020 | Details |
| A30395 | 32508961 | Nutr Metab (Lond) | High-trans fatty acid and high-sugar diets can cause mice with non-alcoholic steatohepatitis with liver fibrosis and potential pathogenesis. | 2020 | Details |
| A30407 | 32493884 | Exp Anim | Gender difference in development of steatohepatitis in p62/Sqstm1 and Nrf2 double-knockout mice. | 2020 | Details |
| A30441 | 32441510 | ACS Nano | Targeted Delivery of Notch Inhibitor Attenuates Obesity-Induced Glucose Intolerance and Liver Fibrosis. | 2020 | Details |
| A30495 | 32341704 | J Med Life | Signification of Serum Alpha-Fetoprotein Levels in Cases of Compensated Cirrhosis and Hepatitis C Virus without Hepatocellular Carcinoma. | 2020 | Details |
| A30513 | 32309315 | Ann Transl Med | Palmitic acid stimulates NLRP3 inflammasome activation through TLR4-NF-κB signal pathway in hepatic stellate cells. | 2020 | Details |
| A30521 | 32289534 | Clin Gastroenterol Hepatol | Noninvasive Markers of Portal Hypertension Detect Decompensation in Overweight or Obese Patients With Compensated Advanced Chronic Liver Disease. | 2020 | Details |
| A30531 | 32283835 | Biology (Basel) | Polymorphisms in Interleukin 13 Signaling and Interacting Genes Predict Advanced Fibrosis and Hepatocellular Carcinoma Development in Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A30540 | 32274350 | J Clin Transl Hepatol | Repurposing Pirfenidone for Nonalcoholic Steatohepatitis-related Cirrhosis: A Case Series. | 2020 | Details |
| A30570 | 32195263 | Front Med (Lausanne) | Myricetin Modulates Macrophage Polarization and Mitigates Liver Inflammation and Fibrosis in a Murine Model of Nonalcoholic Steatohepatitis. | 2020 | Details |
| A30599 | 32140659 | Hepatol Commun | Pirfenidone Is an Agonistic Ligand for PPARα and Improves NASH by Activation of SIRT1/LKB1/pAMPK. | 2020 | Details |
| A30600 | 32140108 | Front Pharmacol | Corrigendum: Progression and Regression of Hepatic Lesions in a Mouse Model of NASH Induced by Dietary Intervention and Its Implications in Pharmacotherapy. | 2020 | Details |
| A30606 | 32121273 | Int J Mol Sci | Reclassifying Hepatic Cell Death during Liver Damage: Ferroptosis-A Novel Form of Non-Apoptotic Cell Death? | 2020 | Details |
| A30637 | 32062834 | J Cell Commun Signal | Neutralizing antibody against osteopontin attenuates non-alcoholic steatohepatitis in mice. | 2020 | Details |
| A30643 | 32055695 | JGH Open | Explant liver evaluation decodes the mystery of cryptogenic cirrhosis! | 2019 | Details |
| A30653 | 32039403 | JHEP Rep | Liver fibrosis and CD206+ macrophage accumulation are suppressed by anti-GM-CSF therapy. | 2019 | Details |
| A30654 | 32039401 | JHEP Rep | Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis. | 2019 | Details |
| A30665 | 32025605 | Hepatol Commun | Icosabutate Exerts Beneficial Effects Upon Insulin Sensitivity, Hepatic Inflammation, Lipotoxicity, and Fibrosis in Mice. | 2019 | Details |
| A30675 | 32012846 | Metabolites | Metabolomic and Lipidomic Biomarkers for Premalignant Liver Disease Diagnosis and Therapy. | 2020 | Details |
| A30684 | 31996485 | JCI Insight | ASK1 inhibition reduces cell death and hepatic fibrosis in an Nlrp3 mutant liver injury model. | 2020 | Details |
| A30685 | 31991602 | Cancers (Basel) | Smad Phospho-Isoforms for Hepatocellular Carcinoma Risk Assessment in Patients with Nonalcoholic Steatohepatitis. | 2020 | Details |
| A30713 | 31921324 | Nutr Metab (Lond) | High levels of dietary methionine improves sitagliptin-induced hepatotoxicity by attenuating oxidative stress in hypercholesterolemic rats. | 2020 | Details |
| A30722 | 31909359 | Hepatol Commun | Farnesoid X Receptor Agonism, Acetyl-Coenzyme A Carboxylase Inhibition, and Back Translation of Clinically Observed Endpoints of De Novo Lipogenesis in a Murine NASH Model. | 2019 | Details |
| A30762 | 31832568 | Hepatol Commun | A Pilot Genome-Wide Analysis Study Identifies Loci Associated With Response to Obeticholic Acid in Patients With NASH. | 2019 | Details |
| A30777 | 31798462 | Front Physiol | Characterising an Alternative Murine Model of Diabetic Cardiomyopathy. | 2019 | Details |
| A30810 | 31747961 | Stem Cell Res Ther | Treatment with adipose tissue-derived mesenchymal stem cells exerts anti-diabetic effects, improves long-term complications, and attenuates inflammation in type 2 diabetic rats. | 2019 | Details |
| A30822 | 31722201 | Cell Rep | Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis. | 2019 | Details |
| A30824 | 31717968 | Int J Mol Sci | The Bile Acid-Phospholipid Conjugate Ursodeoxycholyl-Lysophosphatidylethanolamide (UDCA-LPE) Disintegrates the Lipid Backbone of Raft Plasma Membrane Domains by the Removal of the Membrane Phospholipase A2. | 2019 | Details |
| A30847 | 31680767 | Korean J Physiol Pharmacol | Efficacy of evogliptin and cenicriviroc against nonalcoholic steatohepatitis in mice: a comparative study. | 2019 | Details |
| A30854 | 31667206 | Regen Ther | Mesenchymal stem cells cultured under hypoxic conditions had a greater therapeutic effect on mice with liver cirrhosis compared to those cultured under normal oxygen conditions. | 2019 | Details |
| A30880 | 31620539 | ACG Case Rep J | Intragastric Balloons: An Emerging Therapy for Nonalcoholic Steatohepatitis and Fibrosis? | 2019 | Details |
| A30883 | 31618320 | Clinics (Sao Paulo) | Steatosis and steatohepatitis found in adults after death due to non-burn trauma. | 2019 | Details |
| A30891 | 31611801 | Front Pharmacol | Cyclophilin Inhibitor NV556 Reduces Fibrosis and Hepatocellular Carcinoma Development in Mice With Non-Alcoholic Steatohepatitis. | 2019 | Details |
| A30905 | 31585800 | Mol Ther | MicroRNA 223 3p Negatively Regulates the NLRP3 Inflammasome in Acute and Chronic Liver Injury. | 2019 | Details |
| A30946 | 31497990 | Rev Esp Enferm Dig | Characteristics and survival of hepatocellular carcinoma in non-cirrhotic liver. | 2019 | Details |
| A30948 | 31497743 | Hepatol Commun | A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice. | 2019 | Details |
| A30997 | 31416250 | Cancers (Basel) | Multi-Drug/Gene NASH Therapy Delivery and Selective Hyperspectral NIR Imaging Using Chirality-Sorted Single-Walled Carbon Nanotubes. | 2019 | Details |
| A31006 | 31406003 | J Pharmacol Exp Ther | A Pan-Cyclophilin Inhibitor, CRV431, Decreases Fibrosis and Tumor Development in Chronic Liver Disease Models. | 2019 | Details |
| A31018 | 31388630 | Hepatol Commun | Lipoprotein Lipase Up-regulation in Hepatic Stellate Cells Exacerbates Liver Fibrosis in Nonalcoholic Steatohepatitis in Mice. | 2019 | Details |
| A31019 | 31388629 | Hepatol Commun | Tropifexor-Mediated Abrogation of Steatohepatitis and Fibrosis Is Associated With the Antioxidative Gene Expression Profile in Rodents. | 2019 | Details |
| A31047 | 31321239 | Biomed Res Int | Elafibranor Inhibits Chronic Kidney Disease Progression in NASH Mice. | 2019 | Details |
| A31102 | 31222801 | Hepatology | Hepatocyte TNF Receptor-Associated Factor 6 Aggravates Hepatic Inflammation and Fibrosis by Promoting Lysine 6-Linked Polyubiquitination of Apoptosis Signal-Regulating Kinase 1. | 2019 | Details |
| A31126 | 31201552 | Handb Exp Pharmacol | Obeticholic Acid: An Update of Its Pharmacological Activities in Liver Disorders. | 2019 | Details |
| A31144 | 31177586 | Hepatol Res | Combined effect of a farnesoid X receptor agonist and dipeptidyl peptidase-4 inhibitor on hepatic fibrosis. | 2019 | Details |
| A31179 | 31097447 | Biol Open | Dietary iron restriction leads to a reduction in hepatic fibrosis in a rat model of non-alcoholic steatohepatitis. | 2019 | Details |
| A31189 | 31068812 | Front Pharmacol | Matrine Protects Against MCD-Induced Development of NASH via Upregulating HSP72 and Downregulating mTOR in a Manner Distinctive From Metformin. | 2019 | Details |
| A31241 | 30972180 | Am J Transl Res | Development and validation of an in vitro 3D model of NASH with severe fibrotic phenotype. | 2019 | Details |
| A31250 | 30962742 | Yonago Acta Med | Protective Effects of Ipragliflozin, a Sodium-glucose Cotransporter 2 Inhibitor, on a Non-alcoholic Steatohepatitis Mouse Model. | 2019 | Details |
| A31251 | 30962734 | J Ginseng Res | Fermented ginseng, GBCK25, ameliorates steatosis and inflammation in nonalcoholic steatohepatitis model. | 2017 | Details |
| A31262 | 30949516 | J Diabetes Res | The APOE∗3-Leiden Heterozygous Glucokinase Knockout Mouse as Novel Translational Disease Model for Type 2 Diabetes, Dyslipidemia, and Diabetic Atherosclerosis. | 2019 | Details |
| A31263 | 30949049 | Front Pharmacol | The Inhibitory T Cell Receptors PD1 and 2B4 Are Differentially Regulated on CD4 and CD8 T Cells in a Mouse Model of Non-alcoholic Steatohepatitis. | 2019 | Details |
| A31314 | 30813339 | Nutrients | Interesterified Fats Induce Deleterious Effects on Adipose Tissue and Liver in LDLr-KO Mice. | 2019 | Details |
| A31337 | 30766962 | Hepatol Commun | An Inhibitor of Arginine-Glycine-Aspartate-Binding Integrins Reverses Fibrosis in a Mouse Model of Nonalcoholic Steatohepatitis. | 2018 | Details |
| A31346 | 30755347 | Dig Liver Dis | Comparison of EUS-guided versus percutaneous and transjugular approaches for the performance of liver biopsies. | 2019 | Details |
| A31384 | 30675167 | Stem Cells Int | Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats. | 2018 | Details |
| A31403 | 30637220 | J Clin Transl Hepatol | Nonalcoholic Fatty Liver Disease: Epidemiology, Liver Transplantation Trends and Outcomes, and Risk of Recurrent Disease in the Graft. | 2018 | Details |
| A31413 | 30625404 | Clin Gastroenterol Hepatol | Patients With Signs of Advanced Liver Disease and Clinically Significant Portal Hypertension Do Not Necessarily Have Cirrhosis. | 2019 | Details |
| A31417 | 30615497 | FASEB J | A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling. | 2019 | Details |
| A31419 | 30609442 | Thromb Haemost | Haemostatic Profiles are Similar across All Aetiologies of Cirrhosis. | 2019 | Details |
| A31443 | 30556091 | Singapore Med J | Optimal liver stiffness measurement values for the diagnosis of significant fibrosis and cirrhosis in chronic liver disease in Singapore. | 2018 | Details |
| A31444 | 30556039 | Hepatol Commun | Obeticholic Acid Modulates Serum Metabolites and Gene Signatures Characteristic of Human NASH and Attenuates Inflammation and Fibrosis Progression in Ldlr-/-.Leiden Mice. | 2018 | Details |
| A31486 | 30469530 | Cancers (Basel) | mTOR Activation in Liver Tumors Is Associated with Metabolic Syndrome and Non-Alcoholic Steatohepatitis in Both Mouse Models and Humans. | 2018 | Details |