Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Article ID | PMID | Source | Title | Publish Year | |
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A02527 | 34340957 | Endocrinol Diabetes Nutr (Engl Ed) | Prevalence and predictors of non-alcoholic steatohepatitis in patients with morbid obesity. | 2021 | Details |
A02530 | 34339944 | Phytomedicine | Network pharmacology-based identification of significant pathway for protection of Yinhuang granule in a mice model of metabolic-associated fatty liver disease. | 2021 | Details |
A02534 | 34337887 | J Cachexia Sarcopenia Muscle | Risk stratification using sarcopenia status among subjects with metabolic dysfunction-associated fatty liver disease. | 2021 | Details |
A02539 | 34335686 | Front Genet | The Co-occurrence of Chronic Hepatitis B and Fibrosis Is Associated With a Decrease in Hepatic Global DNA Methylation Levels in Patients With Non-alcoholic Fatty Liver Disease. | 2021 | Details |
A02542 | 34334708 | Eur J Gastroenterol Hepatol | Predictive value of cytokeratin-18 fragment levels for diagnosing steatohepatitis in patients with nonalcoholic fatty liver disease. | 2021 | Details |
A02543 | 34333790 | Hepatology | A Machine Learning Approach to Liver Histological Evaluation Predicts Clinically Significant Portal Hypertension in NASH Cirrhosis. | 2021 | Details |
A02550 | 34331779 | Hepatology | Hepatic Mitochondrial SAB Deletion or Knockdown Alleviates Diet-Induced Metabolic Syndrome, Steatohepatitis, and Hepatic Fibrosis. | 2021 | Details |
A02551 | 34331020 | Pediatr Res | Angiopoietin-2 levels correlates with disease activity in children with nonalcoholic fatty liver disease. | 2021 | Details |
A02553 | 34330512 | Clin Nutr ESPEN | Triglyceride glucose (TyG) index and the progression of liver fibrosis: A cross-sectional study. | 2021 | Details |
A02557 | 34328687 | Liver Int | Zonation in NASH - A key paradigm for understanding pathophysiology and clinical outcomes. | 2021 | Details |
A02562 | 34328087 | Biomed Pharmacother | Supplementation of cumin seed powder prevents oxidative stress, hyperlipidemia and non-alcoholic fatty liver in high fat diet fed rats. | 2021 | Details |
A02570 | 34326695 | Int J Biol Sci | Aberrant FGFR4 signaling worsens nonalcoholic steatohepatitis in FGF21KO mice. | 2021 | Details |
A02571 | 34326608 | World J Gastroenterol | Chronic hepatitis B infection with concomitant hepatic steatosis: Current evidence and opinion. | 2021 | Details |
A02576 | 34325952 | J Formos Med Assoc | The role of fibrosis index FIB-4 in predicting liver fibrosis stage and clinical prognosis: A diagnostic or screening tool? | 2021 | Details |
A02583 | 34322898 | Hepatology | Guanine Nucleotide-Binding Protein G(i) Subunit Alpha 2 Exacerbates NASH Progression by Regulating Peroxiredoxin 1-Related Inflammation and Lipophagy. | 2021 | Details |
A02586 | 34321990 | Prz Menopauzalny | Bariatric surgery: blessing or sometimes curse for the liver? | 2021 | Details |
A02587 | 34321850 | World J Gastroenterol | PPARGC1A rs8192678 G>A polymorphism affects the severity of hepatic histological features and nonalcoholic steatohepatitis in patients with nonalcoholic fatty liver disease. | 2021 | Details |
A02594 | 34321089 | Stem Cell Res Ther | Addressing the liver progenitor cell response and hepatic oxidative stress in experimental non-alcoholic fatty liver disease/non-alcoholic steatohepatitis using amniotic epithelial cells. | 2021 | Details |
A02597 | 34320238 | Hepatology | SIMPLE Is an Endosomal Regulator That Protects Against NAFLD by Targeting the Lysosomal Degradation of EGFR. | 2021 | Details |
A02599 | 34319647 | Mol Nutr Food Res | The Association Between Coffee Consumption and Nonalcoholic Fatty Liver Disease in the South Korean General Population. | 2021 | Details |
A02601 | 34314787 | Adv Drug Deliv Rev | Therapeutic targets, novel drugs, and delivery systems for diabetes associated NAFLD and liver fibrosis. | 2021 | Details |
A02606 | 34311531 | Biomed Pharmacother | FTZ attenuates liver steatosis and fibrosis in the minipigs with type 2 diabetes by regulating the AMPK signaling pathway. | 2021 | Details |
A02607 | 34311134 | Clin Res Hepatol Gastroenterol | Non-invasive assessment of fibrosis and steatosis in pediatric non-alcoholic fatty liver disease. | 2021 | Details |
A02610 | 34310978 | Gastroenterology | TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial. | 2021 | Details |
A02619 | 34307562 | World J Clin Cases | Impact of continuous positive airway pressure therapy for nonalcoholic fatty liver disease in patients with obstructive sleep apnea. | 2021 | Details |
A02620 | 34307250 | Front Pediatr | Possible Hepatoprotective Effect of Tocotrienol-Rich Fraction Vitamin E in Non-alcoholic Fatty Liver Disease in Obese Children and Adolescents. | 2021 | Details |
A02627 | 34304139 | Biomaterials | A fully defined matrix to support a pluripotent stem cell derived multi-cell-liver steatohepatitis and fibrosis model. | 2021 | Details |
A02628 | 34303881 | Cell Mol Gastroenterol Hepatol | White Adipose Tissue Autophagy and Adipose-Liver Crosstalk Exacerbate Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
A02629 | 34303827 | Clin Res Hepatol Gastroenterol | Metabolically healthy and unhealthy obesity and the progression of liver fibrosis: A cross-sectional study. | 2021 | Details |
A02636 | 34300193 | J Clin Med | Serum Visfatin Levels in Nonalcoholic Fatty Liver Disease and Liver Fibrosis: Systematic Review and Meta-Analysis. | 2021 | Details |
A02639 | 34299321 | Int J Mol Sci | Mitochondria Matter: Systemic Aspects of Nonalcoholic Fatty Liver Disease (NAFLD) and Diagnostic Assessment of Liver Function by Stable Isotope Dynamic Breath Tests. | 2021 | Details |
A02640 | 34299189 | Int J Mol Sci | Current Options and Future Directions for NAFLD and NASH Treatment. | 2021 | Details |
A02642 | 34298967 | Int J Mol Sci | Recent Progress in the Molecular Imaging of Nonalcoholic Fatty Liver Disease. | 2021 | Details |
A02644 | 34298870 | Int J Mol Sci | Liver Injury and the Macrophage Issue: Molecular and Mechanistic Facts and Their Clinical Relevance. | 2021 | Details |
A02648 | 34298687 | Cancers (Basel) | Abnormal Metabolism in the Progression of Nonalcoholic Fatty Liver Disease to Hepatocellular Carcinoma: Mechanistic Insights to Chemoprevention. | 2021 | Details |
A02652 | 34297733 | PLoS One | Long working hours are associated with a higher risk of non-alcoholic fatty liver disease: A large population-based Korean cohort study. | 2021 | Details |
A02653 | 34297426 | Hepatology | Gastrodin Improves Nonalcoholic Fatty Liver Disease Through Activation of the Adenosine Monophosphate-Activated Protein Kinase Signaling Pathway. | 2021 | Details |
A02655 | 34295993 | Clin Exp Hepatol | Comparative analysis of metabolic risk factors for progression of non-alcoholic fatty liver disease. | 2021 | Details |
A02657 | 34295984 | Clin Exp Hepatol | Pemafibrate improves hepatic inflammation, function and fibrosis in patients with non-alcoholic fatty liver disease: a one-year observational study. | 2021 | Details |
A02658 | 34294937 | Pathologica | Pathology of non-alcoholic fatty liver disease. | 2021 | Details |
A02659 | 34294714 | Nat Commun | CD8+ tissue-resident memory T cells promote liver fibrosis resolution by inducing apoptosis of hepatic stellate cells. | 2021 | Details |
A02660 | 34294656 | J Clin Gastroenterol | Identifying Patients at Risk for Fibrosis in a Primary Care NAFLD Cohort. | 2021 | Details |
A02662 | 34294375 | J Pharmacol Sci | Ferulic acid attenuates non-alcoholic steatohepatitis by reducing oxidative stress and inflammation through inhibition of the ROCK/NF-κB signaling pathways. | 2021 | Details |
A02665 | 34292604 | Hepatology | Salidroside Activates the AMP-Activated Protein Kinase Pathway to Suppress Nonalcoholic Steatohepatitis in Mice. | 2021 | Details |
A02670 | 34290320 | Sci Rep | AST to Platelet Ratio Index (APRI) is an easy-to-use predictor score for cardiovascular risk in metabolic subjects. | 2021 | Details |
A02673 | 34289507 | Semin Liver Dis | Role of FXR in Bile Acid and Metabolic Homeostasis in NASH: Pathogenetic Concepts and Therapeutic Opportunities. | 2021 | Details |
A02675 | 34289397 | J Hepatol | Maternal obesity increases the risk and severity of NAFLD in offspring. | 2021 | Details |
A02686 | 34284414 | Eur J Gastroenterol Hepatol | Heritability analysis of liver stiffness detected by ultrasound shear wave elastography: a twin study. | 2021 | Details |
A02691 | 34280550 | Clin Gastroenterol Hepatol | Risk Difference of Liver-Related and Cardiovascular Events by Liver Fibrosis Status in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
A02692 | 34280515 | Adv Drug Deliv Rev | Pathophysiological communication between hepatocytes and non-parenchymal cells in liver injury from NAFLD to liver fibrosis. | 2021 | Details |
A02693 | 34280397 | Eur J Pharmacol | Thymosin beta 4 alleviates non-alcoholic fatty liver by inhibiting ferroptosis via up-regulation of GPX4. | 2021 | Details |
A02700 | 34278170 | Hepatol Commun | Colonoscopy and Risk of Colorectal Cancer in Patients With Nonalcoholic Fatty Liver Disease: A Retrospective Territory-Wide Cohort Study. | 2021 | Details |
A02701 | 34278169 | Hepatol Commun | Improvements of Fibrosis and Disease Activity Are Associated With Improvement of Patient-Reported Outcomes in Patients With Advanced Fibrosis Due to Nonalcoholic Steatohepatitis. | 2021 | Details |
A02707 | 34277457 | Front Oncol | Hepcidin Downregulation Correlates With Disease Aggressiveness And Immune Infiltration in Liver Cancers. | 2021 | Details |
A02710 | 34276360 | Front Pharmacol | Network Pharmacological Analysis and Experimental Validation of the Mechanisms of Action of Si-Ni-San Against Liver Fibrosis. | 2021 | Details |
A02712 | 34276197 | Ann Gastroenterol | Modest alcohol consumption and risk of advanced liver fibrosis in nonalcoholic fatty liver disease: a systematic review and meta-analysis. | 2021 | Details |
A02713 | 34276185 | Ann Gastroenterol | Alcohol consumption in patients with nonalcoholic fatty liver disease: yes, or no? | 2021 | Details |
A02714 | 34276153 | J Clin Exp Hepatol | Screening of Family Members of Nonalcoholic Fatty Liver Disease Patients can Detect Undiagnosed Nonalcoholic Fatty Liver Disease Among Them: Is There a Genetic Link? | 2020 | Details |
A02716 | 34275749 | Hepatobiliary Pancreat Dis Int | Influence of weight management on the prognosis of steatohepatitis in chronic hepatitis B patients during antiviral treatment. | 2021 | Details |
A02725 | 34272900 | Int J Eat Disord | Binge-eating disorder is associated with an unfavorable body mass composition in patients with non-alcoholic fatty liver disease. | 2021 | Details |
A02726 | 34272738 | Hepatology | The E3 Ubiquitin Ligase Ring Finger Protein 5 Ameliorates NASH Through Ubiquitin-Mediated Degradation of 3-Hydroxy-3-Methylglutaryl CoA Reductase Degradation Protein 1. | 2021 | Details |
A02732 | 34268860 | Liver Int | NR1H4 rs35724 G>C variant modulates liver damage in nonalcoholic fatty liver disease. | 2021 | Details |
A02734 | 34266657 | Clin Radiol | The feasibility of T2 mapping in the assessment of hepatic steatosis, inflammation, and fibrosis in patients with non-alcoholic fatty liver disease: a preliminary study. | 2021 | Details |
A02741 | 34263075 | JGH Open | Validation of a two-step approach combining serum biomarkers and liver stiffness measurement to predict advanced fibrosis. | 2021 | Details |
A02742 | 34263067 | JGH Open | Noninvasive measure of treatment response in non-alcoholic steatohepatitis: Insights from EMMINENCE and meta-analysis. | 2021 | Details |
A02746 | 34262313 | Diabetes Metab Syndr Obes | Liver Stiffness Measurement by Using Transient Elastography in Bangladeshi Patients with Type 2 Diabetes Mellitus and Ultrasonography-Diagnosed Nonalcoholic Fatty Liver Disease. | 2021 | Details |
A02752 | 34259747 | Rev Col Bras Cir | Is there a link between non-alcoholic fatty liver disease aspects and pancreatic cancer? Results of a case-matched study. | 2021 | Details |
A02755 | 34257827 | Oxid Med Cell Longev | Changes in Key Mitochondrial Lipids Accompany Mitochondrial Dysfunction and Oxidative Stress in NAFLD. | 2021 | Details |
A02760 | 34256994 | Hepatobiliary Pancreat Dis Int | LC-MS-based lipidomic analysis in distinguishing patients with nonalcoholic steatohepatitis from nonalcoholic fatty liver. | 2021 | Details |
A02762 | 34254372 | Phytother Res | The effect of (Cornus mas L.) fruit extract on liver function among patients with nonalcoholic fatty liver: A double-blind randomized clinical trial. | 2021 | Details |
A02764 | 34253010 | Diabetes Metab J | Renal Tubular Damage Marker, Urinary N-acetyl-β-D-Glucosaminidase, as a Predictive Marker of Hepatic Fibrosis in Type 2 Diabetes Mellitus. | 2021 | Details |
A02765 | 34252441 | Eur J Pharmacol | Ferroptosis as a new therapeutic opportunity for nonviral liver disease. | 2021 | Details |
A02767 | 34251031 | Aliment Pharmacol Ther | PRO-C3 and ADAPT algorithm accurately identify patients with advanced fibrosis due to alcohol-related liver disease. | 2021 | Details |
A02768 | 34250613 | J Clin Periodontol | Elimination of Porphyromonas gingivalis inhibits liver fibrosis and inflammation in NASH. | 2021 | Details |
A02770 | 34249975 | Front Med (Lausanne) | Adiponectin, Leptin, and IGF-1 Are Useful Diagnostic and Stratification Biomarkers of NAFLD. | 2021 | Details |
A02773 | 34249410 | Am J Cancer Res | Targeting the eicosanoid pathway in hepatocellular carcinoma. | 2021 | Details |
A02775 | 34248137 | Med Sci Monit | Editorial: International Consensus Recommendations to Replace the Terminology of Non-Alcoholic Fatty Liver Disease (NAFLD) with Metabolic-Associated Fatty Liver Disease (MAFLD). | 2021 | Details |
A02776 | 34246549 | Hepatobiliary Pancreat Dis Int | The pathologic relevance of metabolic criteria in patients with biopsy-proven nonalcoholic fatty liver disease and metabolic dysfunction associated fatty liver disease: A multicenter cross-sectional study in China. | 2021 | Details |
A02779 | 34243681 | Pharm Biol | Esculin protects against methionine choline-deficient diet-induced non-alcoholic steatohepatitis by regulating the Sirt1/NF-κB p65 pathway. | 2021 | Details |
A02780 | 34243194 | Semin Liver Dis | Risks and Rewards of Bariatric Surgery in Advanced Chronic Liver Diseases. | 2021 | Details |
A02781 | 34243193 | Semin Liver Dis | Management of Obesity and Nonalcoholic Fatty Liver Disease: A Literature Review. | 2021 | Details |
A02782 | 34242868 | Comput Biol Med | Application of computer tongue image analysis technology in the diagnosis of NAFLD. | 2021 | Details |
A02783 | 34242696 | J Hepatol | The multifaceted role of cathepsins in liver disease. | 2021 | Details |
A02791 | 34239263 | World J Gastroenterol | Non-cirrhotic hepatocellular carcinoma in chronic viral hepatitis: Current insights and advancements. | 2021 | Details |
A02792 | 34239138 | Nat Med | Efruxifermin in non-alcoholic steatohepatitis: a randomized, double-blind, placebo-controlled, phase 2a trial. | 2021 | Details |
A02793 | 34238770 | Gut Liver | Cardiovascular Risk Is Elevated in Lean Subjects with Nonalcoholic Fatty Liver Disease. | 2022 | Details |
A02795 | 34237252 | Cell Metab | Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication. | 2021 | Details |
A02801 | 34234538 | Int J Gen Med | Correlation Between 25 Hydroxyvitamin D Levels and Nonalcoholic Fatty Liver Disease in Chinese Patients with Type 2 Diabetes Mellitus: A Cross-Sectional Study. | 2021 | Details |
A02805 | 34234198 | Sci Rep | Utility of Fibroscan XL to assess the severity of non-alcoholic fatty liver disease in patients undergoing bariatric surgery. | 2021 | Details |
A02806 | 34234100 | Cell Death Discov | Exosomes secreted by palmitic acid-treated hepatocytes promote LX-2 cell activation by transferring miRNA-107. | 2021 | Details |
A02815 | 34231659 | Arq Gastroenterol | PERFORMACE OF TRIGLYCERIDE-GLUCOSE INDEX ON DIAGNOSIS AND STAGING OF NAFLD IN OBESE PATIENTS. | 2021 | Details |
A02816 | 34231477 | Turk J Gastroenterol | Feasibility of Fibroscan in Assessment of Hepatic Steatosis and Fibrosis in Obese Patients: Report From a General Internal Medicine Clinic. | 2021 | Details |
A02823 | 34229251 | Biomed Pharmacother | Bicyclol ameliorates nonalcoholic fatty liver disease in mice via inhibiting MAPKs and NF-κB signaling pathways. | 2021 | Details |
A02828 | 34227068 | Eur Rev Med Pharmacol Sci | Liver changes in Wilson's disease: the full spectrum. A report of 127 biopsies from 43 patients. | 2021 | Details |
A02830 | 34226630 | Sci Rep | The FibroScan-aspartate aminotransferase score can stratify the disease severity in a Japanese cohort with fatty liver diseases. | 2021 | Details |
A02833 | 34225440 | Zhonghua Gan Zang Bing Za Zhi | [Research progress of omics biomarkers for nonalcoholic fatty liver disease]. | 2021 | Details |
A02834 | 34225438 | Zhonghua Gan Zang Bing Za Zhi | [Mechanism of T lymphocyte subsets in the malignant transformation of non-alcoholic fatty liver disease]. | 2021 | Details |
A02836 | 34224858 | Pharmacol Res | Mastiha has efficacy in immune-mediated inflammatory diseases through a microRNA-155 Th17 dependent action. | 2021 | Details |
A02840 | 34222711 | Curr Opin Endocr Metab Res | Pediatric nonalcoholic fatty liver disease and the microbiome: Mechanisms contributing to pathogenesis and progression. | 2021 | Details |
A02846 | 34221262 | Gastroenterol Hepatol Bed Bench | Is melatonin associated with pro-inflammatory cytokine activity and liver fibrosis in non-alcoholic fatty liver disease (NAFLD) patients? | 2021 | Details |