Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A35238 | 21335007 | Gastroenterology | Iron levels in hepatocytes and portal tract cells predict progression and outcomes of patients with advanced chronic hepatitis C. | 2011 | Details |
| A35241 | 21321532 | Lab Invest | Blockade of IL-6 signaling exacerbates liver injury and suppresses antiapoptotic gene expression in methionine choline-deficient diet-fed db/db mice. | 2011 | Details |
| A35252 | 21291347 | Expert Opin Ther Targets | Targets of chymase inhibitors. | 2011 | Details |
| A35259 | 21276150 | Hepatol Res | Pitavastatin inhibits hepatic steatosis and fibrosis in non-alcoholic steatohepatitis model rats. | 2011 | Details |
| A35261 | 21272072 | Clin Transplant | Outcomes of patients with cystic fibrosis undergoing lung transplantation with and without cystic fibrosis-associated liver cirrhosis. | 2011 | Details |
| A35289 | 25013596 | Int J Organ Transplant Med | Recurrence of Disease Following Liver Transplantation: Nonalcoholic Steatohepatitis vs Hepatitis C Virus Infection. | 2011 | Details |
| A35317 | 21114431 | Scand J Gastroenterol | Non-alcoholic steatohepatitis (NASH) in patients with polycystic ovarian syndrome (PCOS). | 2010 | Details |
| A35325 | 21081801 | J Physiol Pharmacol | The effects of L-tryptophan and melatonin on selected biochemical parameters in patients with steatohepatitis. | 2010 | Details |
| A35342 | 21046243 | Dig Dis Sci | Small intestinal bacterial overgrowth in nonalcoholic steatohepatitis: association with toll-like receptor 4 expression and plasma levels of interleukin 8. | 2010 | Details |
| A35352 | 21038418 | Hepatology | Evolution of inflammation in nonalcoholic fatty liver disease: the multiple parallel hits hypothesis. | 2010 | Details |
| A35364 | 20953526 | Saudi Med J | Antioxidant and hepatoprotective effects of extract of ginkgo biloba in rats of non-alcoholic steatohepatitis. | 2010 | Details |
| A35388 | 20846698 | Metabolism | Regulation of synthesis and oxidation of fatty acids by adiponectin receptors (AdipoR1/R2) and insulin receptor substrate isoforms (IRS-1/-2) of the liver in a nonalcoholic steatohepatitis animal model. | 2010 | Details |
| A35407 | 20818485 | Int J Mol Med | Prevention and regression of non-alcoholic steatohepatitis (NASH) in a rat model by metabosartan, telmisartan. | 2010 | Details |
| A35424 | 20731020 | World J Gastroenterol | Hepatocellular carcinoma in patients with chronic hepatitis C virus infection without cirrhosis. | 2010 | Details |
| A35427 | 20724519 | Clin J Am Soc Nephrol | Relationship between kidney function and liver histology in subjects with nonalcoholic steatohepatitis. | 2010 | Details |
| A35434 | 20683968 | Hepatology | Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: the central role of nontriglyceride fatty acid metabolites. | 2010 | Details |
| A35435 | 20683947 | Hepatology | High-dose ursodeoxycholic acid therapy for nonalcoholic steatohepatitis: a double-blind, randomized, placebo-controlled trial. | 2010 | Details |
| A35442 | 26190246 | Clin J Gastroenterol | A fatal case of progressive steatohepatitis, possibly chemotherapy-associated steatohepatitis related to gemcitabine. | 2010 | Details |
| A35444 | 20662773 | Aliment Pharmacol Ther | Pioglitazone in the treatment of NASH: the role of adiponectin. | 2010 | Details |
| A35453 | 20625232 | J Oleo Sci | Effects of docosahexaenoic acid in an experimental rat model of nonalcoholic steatohepatitis. | 2010 | Details |
| A35460 | 20607689 | Hepatology | High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. | 2010 | Details |
| A35462 | 20606728 | Int J Clin Exp Pathol | Regulation of oxidative stress and inflammation by hepatic adiponectin receptor 2 in an animal model of nonalcoholic steatohepatitis. | 2010 | Details |
| A35464 | 20596733 | J Gastroenterol | Absence of invariant natural killer T cells deteriorates liver inflammation and fibrosis in mice fed high-fat diet. | 2010 | Details |
| A35490 | 20548288 | Lab Invest | Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice. | 2010 | Details |
| A35495 | 20540856 | Zhongguo Dang Dai Er Ke Za Zhi | [Determination and clinical significance of tissue inhibitors of metalloproteinase-1 and -2 in serum of children with nonalcoholic fatty liver disease]. | 2010 | Details |
| A35509 | 20489159 | Am J Pathol | A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits. | 2010 | Details |
| A35511 | 20486204 | J Clin Lab Anal | Serum prolidase enzyme activity and its relation to histopathological findings in patients with non-alcoholic steatohepatitis. | 2010 | Details |
| A35530 | 20427778 | N Engl J Med | Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. | 2010 | Details |
| A35538 | 20412324 | Hepatol Res | Efficacy of ezetimibe for the treatment of non-alcoholic steatohepatitis: An open-label, pilot study. | 2010 | Details |
| A35539 | 20408954 | Liver Int | Apoptosis is associated with CD36/fatty acid translocase upregulation in non-alcoholic steatohepatitis. | 2010 | Details |
| A35544 | 20395294 | J Biol Chem | Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione. | 2010 | Details |
| A35551 | 20376504 | J Gastroenterol | Prospective study of hepatocellular carcinoma in nonalcoholic steatohepatitis in comparison with hepatocellular carcinoma caused by chronic hepatitis C. | 2010 | Details |
| A35554 | 20374300 | Hepatol Res | Chymase inhibitor prevents the nonalcoholic steatohepatitis in hamsters fed a methionine- and choline-deficient diet. | 2010 | Details |
| A35555 | 20373454 | Liver Transpl | Nonalcoholic fatty liver disease after liver transplantation for cryptogenic cirrhosis or nonalcoholic fatty liver disease. | 2010 | Details |
| A35557 | 20368703 | Lab Invest | Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice. | 2010 | Details |
| A35563 | 20361076 | J Gastrointestin Liver Dis | Performance of unidimensional transient elastography in staging non-alcoholic steatohepatitis. | 2010 | Details |
| A35570 | 20347818 | Gastroenterology | Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. | 2010 | Details |
| A35573 | 20336392 | Obes Surg | A noninvasive clinical scoring model predicts risk of nonalcoholic steatohepatitis in morbidly obese patients. | 2010 | Details |
| A35580 | 20302666 | BMC Genomics | Library of molecular associations: curating the complex molecular basis of liver diseases. | 2010 | Details |
| A35584 | 20236361 | Hepatol Res | Identification of a novel biomarker for oxidative stress induced by hydrogen peroxide in primary human hepatocytes using the 2-nitrobenzenesulfenyl chloride isotope labeling method. | 2010 | Details |
| A35593 | 20206177 | Gastroenterology | Role of scavenger receptor A and CD36 in diet-induced nonalcoholic steatohepatitis in hyperlipidemic mice. | 2010 | Details |
| A35621 | 20101752 | Hepatology | Prognostic value of Ishak fibrosis stage: findings from the hepatitis C antiviral long-term treatment against cirrhosis trial. | 2010 | Details |
| A35633 | 19996485 | J Physiol Pharmacol | Adipohormones as prognostric markers in patients with nonalcoholic steatohepatitis (NASH). | 2009 | Details |
| A35639 | 21483580 | Libyan J Med | A preliminary study of inflammatory markers in non-alcoholic steatohepatitis patients. | 2010 | Details |
| A35640 | 20041267 | Surg Endosc | Adiponectin but not leptin is involved in early hepatic disease in morbidly obese patients. | 2009 | Details |
| A35659 | 19998387 | Hepatology | Major histocompatibility complex class I-related chains A and B (MIC A/B): a novel role in nonalcoholic steatohepatitis. | 2010 | Details |
| A35675 | 19938191 | World J Gastroenterol | Immunotherapy for nonalcoholic steatohepatitis using the multiple cytokine production modulator Y-40138. | 2009 | Details |
| A35692 | 19902480 | Hepatology | Toxicant-associated steatohepatitis in vinyl chloride workers. | 2010 | Details |
| A35693 | 19902025 | J Clin Biochem Nutr | A Novel Animal Model of Nonalcoholic Steatohepatitis (NASH): Hypoxemia Enhances the Development of NASH. | 2009 | Details |
| A35694 | 19902023 | J Clin Biochem Nutr | Development of Fibrosis in Nonalcoholic Steatosis through Combination of a Synthetic Diet Rich in Disaccharide and Low-Dose Lipopolysaccharides in the Livers of Zucker (fa/fa) Rats. | 2009 | Details |
| A35700 | 19877169 | Hepatology | Long-term efficacy of rosiglitazone in nonalcoholic steatohepatitis: results of the fatty liver improvement by rosiglitazone therapy (FLIRT 2) extension trial. | 2010 | Details |
| A35710 | 19856102 | Dig Dis Sci | Highly purified eicosapentaenoic acid ethyl ester prevents development of steatosis and hepatic fibrosis in rats. | 2009 | Details |
| A35720 | 19841616 | Lab Invest | Curcumin attenuates the effects of insulin on stimulating hepatic stellate cell activation by interrupting insulin signaling and attenuating oxidative stress. | 2009 | Details |
| A35728 | 19824078 | Hepatology | Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial. | 2009 | Details |
| A35744 | 19785957 | Zhonghua Gan Zang Bing Za Zhi | [Role of resistin in inflammation of hepatocytes in nonalcoholic steatohepatitis]. | 2009 | Details |
| A35753 | 19764881 | Antioxid Redox Signal | Thioredoxin-binding protein-2 deficiency enhances methionine-choline deficient diet-induced hepatic steatosis but inhibits steatohepatitis in mice. | 2009 | Details |
| A35768 | 19736547 | Lab Invest | Curcumin eliminates oxidized LDL roles in activating hepatic stellate cells by suppressing gene expression of lectin-like oxidized LDL receptor-1. | 2009 | Details |
| A35778 | 19712272 | Hepatol Res | Clinical significance of serum ornithine carbamoyltransferase in patients with non-alcoholic steatohepatitis. | 2009 | Details |
| A35794 | 19676128 | Hepatology | Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C. | 2009 | Details |
| A35797 | 19672551 | J Gastroenterol | Hepatocellular carcinoma arising from non-cirrhotic nonalcoholic steatohepatitis. | 2009 | Details |
| A35801 | 19659788 | J Dig Dis | Diagnostic value of a group of biochemical markers of liver fibrosis in patients with non-alcoholic steatohepatitis. | 2009 | Details |
| A35822 | 19606393 | Scand J Gastroenterol | Antioxidants vitamin E and 1-aminobenzotriazole prevent experimental non-alcoholic steatohepatitis in mice. | 2009 | Details |
| A35833 | 19581764 | Korean J Hepatol | [Pathology of nonalcoholic steatohepatitis]. | 2009 | Details |
| A35843 | 19562718 | Liver Transpl | Recurrent familial hypobetalipoproteinemia-induced nonalcoholic fatty liver disease after living donor liver transplantation. | 2009 | Details |
| A35856 | 19552763 | J Pineal Res | Melatonin ameliorates methionine- and choline-deficient diet-induced nonalcoholic steatohepatitis in rats. | 2009 | Details |
| A35864 | 19540686 | Gastroenterol Clin Biol | [Nonalcoholic fatty liver disease: 30 years research changed NASH]. | 2009 | Details |
| A35883 | 19501928 | J Hepatol | Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis. | 2009 | Details |
| A35884 | 19501927 | J Hepatol | Farnesoid X receptor agonist WAY-362450 attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis. | 2009 | Details |
| A35897 | 19473432 | Hepatol Res | Treatment of nonalcoholic steatohepatitis with colestimide. | 2009 | Details |
| A35901 | 19454484 | Hum Mol Genet | Diet-induced hepatocellular carcinoma in genetically predisposed mice. | 2009 | Details |
| A35902 | 19453544 | Hepatol Res | Effects of estrogen and androgen deprivation on the progression of non-alcoholic steatohepatitis (NASH) in male Sprague-Dawley rats. | 2009 | Details |
| A35906 | 19448566 | J Clin Gastroenterol | A pilot study using simvastatin in the treatment of nonalcoholic steatohepatitis: A randomized placebo-controlled trial. | 2010 | Details |
| A35909 | 19434740 | Hepatology | Nutritional model of steatohepatitis and metabolic syndrome in the Ossabaw miniature swine. | 2009 | Details |
| A35912 | 19430612 | J Clin Biochem Nutr | Beneficial Effects of Fermented Green Tea Extract in a Rat Model of Non-alcoholic Steatohepatitis. | 2009 | Details |
| A35913 | 19424798 | Dig Dis Sci | Protective effects of the carotenoid zeaxanthin in experimental nonalcoholic steatohepatitis. | 2009 | Details |
| A35917 | 19416517 | BMC Res Notes | Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat. | 2009 | Details |
| A35919 | 19404342 | Acta Med Okayama | Beneficial effects of Vitis coignetiae Pulliat leaves on nonalcoholic steatohepatitis in a rat model. | 2009 | Details |
| A35950 | 19356874 | Magn Reson Imaging | MRI findings in nonalcoholic steatohepatitis: correlation with histopathology and clinical staging. | 2009 | Details |
| A35964 | 19318980 | J Clin Gastroenterol | Thiazolidinediones for the treatment in NASH: sustained benefit after drug discontinuation? | 2009 | Details |
| A35969 | 19299451 | Endocrinology | Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling. | 2009 | Details |
| A35974 | 19294996 | Rev Med Chir Soc Med Nat Iasi | [Involvement and role of iron in nonalcoholic steatohepatitis]. | 2009 | Details |
| A35975 | 19291787 | Hepatology | Evolution of hepatic steatosis in patients with advanced hepatitis C: results from the hepatitis C antiviral long-term treatment against cirrhosis (HALT-C) trial. | 2009 | Details |
| A35983 | 19273538 | Rheumatology (Oxford) | Liver fibrosis in patients with psoriasis and psoriatic arthritis on long-term, high cumulative dose methotrexate therapy. | 2009 | Details |
| A35996 | 24842131 | Arab J Gastroenterol | Non-invasive fibrosis seromarkers as a predictor of liver fibrosis in chronic hepatitis C and/or non-alcoholic steatohepatitis. | 2009 | Details |
| A36000 | 19248189 | World J Gastroenterol | A rabbit model of pediatric nonalcoholic steatohepatitis: the role of adiponectin. | 2009 | Details |
| A36006 | 19148800 | J Gastroenterol | Hepatocellular carcinoma in patients with nonalcoholic steatohepatitis. | 2009 | Details |
| A36010 | 19215600 | Addiction | Drinking patterns, dependency and life-time drinking history in alcohol-related liver disease. | 2008 | Details |
| A36011 | 19208039 | Hepatol Res | Murid herpesvirus-4 induces chronic inflammation of intrahepatic bile ducts in mice deficient in gamma-interferon signalling. | 2009 | Details |
| A36066 | 19085967 | Hepatology | Liver damage underlying unexplained transaminase elevation in human immunodeficiency virus-1 mono-infected patients on antiretroviral therapy. | 2009 | Details |
| A36078 | 19052125 | N Engl J Med | Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon. | 2008 | Details |
| A36092 | 19026502 | Eur J Radiol | New proposal for the staging of nonalcoholic steatohepatitis: evaluation of liver fibrosis on Gd-EOB-DTPA-enhanced MRI. | 2008 | Details |
| A36094 | 19013295 | Metabolism | Efficacy of atorvastatin for the treatment of nonalcoholic steatohepatitis with dyslipidemia. | 2008 | Details |
| A36112 | 18991162 | Scand J Gastroenterol | Rosiglitazone prevents nutritional fibrosis and steatohepatitis in mice. | 2009 | Details |
| A36116 | 18986378 | Alcohol Clin Exp Res | Nitric oxide plays a crucial role in the development/progression of nonalcoholic steatohepatitis in the choline-deficient, l-amino acid-defined diet-fed rat model. | 2009 | Details |
| A36118 | 18984468 | Clin Liver Dis | Disease-specific mechanisms of fibrosis: hepatitis C virus and nonalcoholic steatohepatitis. | 2008 | Details |
| A36141 | 18948497 | J Pharmacol Exp Ther | Farnesoid X receptor deficiency induces nonalcoholic steatohepatitis in low-density lipoprotein receptor-knockout mice fed a high-fat diet. | 2008 | Details |
| A36159 | 18848945 | Gastroenterology | Development of nonalcoholic steatohepatitis in insulin-resistant liver-specific S503A carcinoembryonic antigen-related cell adhesion molecule 1 mutant mice. | 2008 | Details |
| A36160 | 18848939 | Gastroenterology | Incidence of hepatocellular carcinoma and associated risk factors in hepatitis C-related advanced liver disease. | 2008 | Details |
| A36169 | 18829391 | Clin Gastroenterol Hepatol | Placebo in nonalcoholic steatohepatitis: insight into natural history and implications for future clinical trials. | 2008 | Details |
| A36179 | 18806095 | J Nutr | N-acetylcysteine attenuates progression of liver pathology in a rat model of nonalcoholic steatohepatitis. | 2008 | Details |