Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A02851 | 34219352 | Liver Int | Incidence of liver-related morbidity and mortality in a population cohort of non-alcoholic fatty liver disease. | 2021 | Details |
| A02854 | 34218773 | Curr Pharm Des | Vanillic Acid and Non-Alcoholic Fatty Liver Disease: A Focus on AMPK in Adipose and Liver Tissues. | 2021 | Details |
| A02855 | 34214678 | Clin Gastroenterol Hepatol | Physical Activity Is Associated With Nonalcoholic Fatty Liver Disease and Significant Fibrosis Measured by FibroScan. | 2021 | Details |
| A02856 | 34214585 | Eur J Pharmacol | The leukotriene receptor antagonist montelukast in the treatment of non-alcoholic steatohepatitis: A proof-of-concept, randomized, double-blind, placebo-controlled trial. | 2021 | Details |
| A02857 | 34214406 | Expert Opin Investig Drugs | Anti-diabetic drugs and NASH: from current options to promising perspectives. | 2021 | Details |
| A02860 | 34213784 | Phytother Res | Corosolic acid ameliorates non-alcoholic steatohepatitis induced by high-fat diet and carbon tetrachloride by regulating TGF-β1/Smad2, NF-κB, and AMPK signaling pathways. | 2021 | Details |
| A02862 | 34213039 | J Clin Lab Anal | Risk of severe illness of COVID-19 patients with NAFLD and increased NAFLD fibrosis scores. | 2021 | Details |
| A02863 | 34212895 | Am J Gastroenterol | Chemopreventive Effect of Statin on Hepatocellular Carcinoma in Patients With Nonalcoholic Steatohepatitis Cirrhosis. | 2021 | Details |
| A02864 | 34212294 | Clin Exp Med | An exploratory analysis of the competing effects of alcohol use and advanced hepatic fibrosis on serum HDL. | 2021 | Details |
| A02874 | 34209858 | J Clin Med | Systematic Review with Meta-Analyses: Diagnostic Accuracy of FibroMeter Tests in Patients with Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A02875 | 34209831 | J Clin Med | TSH Levels as an Independent Risk Factor for NAFLD and Liver Fibrosis in the General Population. | 2021 | Details |
| A02880 | 34207587 | Diagnostics (Basel) | Association of Skeletal Muscle and Adipose Tissue Distribution with Histologic Severity of Non-Alcoholic Fatty Liver. | 2021 | Details |
| A02885 | 34205850 | Molecules | Collagen Characterization in a Model of Nonalcoholic Steatohepatitis with Fibrosis; A Call for Development of Targeted Therapeutics. | 2021 | Details |
| A02886 | 34205674 | Int J Mol Sci | The Evolving Role of Fetuin-A in Nonalcoholic Fatty Liver Disease: An Overview from Liver to the Heart. | 2021 | Details |
| A02891 | 34204343 | Metabolites | Fructose Causes Liver Damage, Polyploidy, and Dysplasia in the Setting of Short Telomeres and p53 Loss. | 2021 | Details |
| A02892 | 34204274 | Int J Mol Sci | Nonalcoholic Fatty Liver Disease (NAFLD) as Model of Gut-Liver Axis Interaction: From Pathophysiology to Potential Target of Treatment for Personalized Therapy. | 2021 | Details |
| A02895 | 34203484 | Int J Mol Sci | Fructose and the Liver. | 2021 | Details |
| A02898 | 34203178 | Int J Mol Sci | Intestinal Permeability Is a Mechanical Rheostat in the Pathogenesis of Liver Cirrhosis. | 2021 | Details |
| A02901 | 34202537 | Int J Mol Sci | Liver Disease: Induction, Progression, Immunological Mechanisms, and Therapeutic Interventions. | 2021 | Details |
| A02904 | 34202179 | Int J Mol Sci | The Alterations of Mitochondrial Function during NAFLD Progression-An Independent Effect of Mitochondrial ROS Production. | 2021 | Details |
| A02906 | 34201382 | Nutrients | Beyond the Paradigm of Weight Loss in Non-Alcoholic Fatty Liver Disease: From Pathophysiology to Novel Dietary Approaches. | 2021 | Details |
| A02907 | 34201230 | Pediatr Rep | Diagnosis and Staging of Pediatric Non-Alcoholic Fatty Liver Disease: Is Classical Ultrasound the Answer? | 2021 | Details |
| A02909 | 34200685 | Metabolites | Metabolomic Study of High-Fat Diet-Induced Obese (DIO) and DIO Plus CCl4-Induced NASH Mice and the Effect of Obeticholic Acid. | 2021 | Details |
| A02912 | 34200525 | J Clin Med | Association between Visceral Adipose Tissue and Non-Alcoholic Steatohepatitis Histology in Patients with Known or Suspected Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
| A02915 | 34199317 | Int J Mol Sci | Empagliflozin Improves Metabolic and Hepatic Outcomes in a Non-Diabetic Obese Biopsy-Proven Mouse Model of Advanced NASH. | 2021 | Details |
| A02919 | 34199098 | Int J Mol Sci | Western Diet Decreases the Liver Mitochondrial Oxidative Flux of Succinate: Insight from a Murine NAFLD Model. | 2021 | Details |
| A02923 | 34198853 | Int J Mol Sci | The Propensity of the Human Liver to Form Large Lipid Droplets Is Associated with PNPLA3 Polymorphism, Reduced INSIG1 and NPC1L1 Expression and Increased Fibrogenetic Capacity. | 2021 | Details |
| A02928 | 34194492 | Int J Endocrinol | Association between High-Density Lipoprotein Cholesterol to Apolipoprotein A-I Ratio and Nonalcoholic Fatty Liver Disease: A Cross-Sectional Study. | 2021 | Details |
| A02932 | 34192596 | Life Sci | Demethylenetetrahydroberberine alleviates nonalcoholic fatty liver disease by inhibiting the NLRP3 inflammasome and oxidative stress in mice. | 2021 | Details |
| A02941 | 34190166 | Medicine (Baltimore) | Therapeutic effects of sleeve gastrectomy for non-alcoholic steatohepatitis estimated by paired liver biopsy in morbidly obese Japanese patients. | 2021 | Details |
| A02944 | 34189448 | JHEP Rep | Epidemiology of non-alcoholic fatty liver disease and hepatocellular carcinoma. | 2021 | Details |
| A02955 | 34185201 | Inflammopharmacology | Molecular and pathobiological involvement of fetuin-A in the pathogenesis of NAFLD. | 2021 | Details |
| A02961 | 34183709 | Sci Rep | The mechanism of increased intestinal palmitic acid absorption and its impact on hepatic stellate cell activation in nonalcoholic steatohepatitis. | 2021 | Details |
| A02962 | 34183428 | Diabetes Care | Circulating Thrombospondin-2 as a Novel Fibrosis Biomarker of Nonalcoholic Fatty Liver Disease in Type 2 Diabetes. | 2021 | Details |
| A02964 | 34183247 | J Diabetes Complications | Non-invasive diagnosis of nonalcoholic fatty liver disease in patients with type 2 diabetes. | 2021 | Details |
| A02968 | 34179738 | JHEP Rep | Embedding assessment of liver fibrosis into routine diabetic review in primary care. | 2021 | Details |
| A02971 | 34178902 | Front Pediatr | Relationship Between Histological Features of Non-alcoholic Fatty Liver Disease and Ectopic Fat on Magnetic Resonance Imaging in Children and Adolescents. | 2021 | Details |
| A02975 | 34176541 | Br J Nutr | Sex influences the association between appendicular skeletal muscle mass to visceral fat area ratio and non-alcoholic steatohepatitis in patients with biopsy-proven non-alcoholic fatty liver disease. | 2021 | Details |
| A02978 | 34176419 | Expert Rev Gastroenterol Hepatol | Chronic liver disease and oxidative stress - a narrative review. | 2021 | Details |
| A02980 | 34175381 | Toxicology | Hepatotoxic potentials of methotrexate: Understanding the possible toxicological molecular mechanisms. | 2021 | Details |
| A02985 | 34174011 | Liver Int | Ultra-processed food is associated with features of metabolic syndrome and non-alcoholic fatty liver disease. | 2021 | Details |
| A02987 | 34173917 | Dig Dis Sci | Impact of Fibrosis-4 Index Prior to COVID-19 on Outcomes in Patients at Risk of Non-alcoholic Fatty Liver Disease. | 2021 | Details |
| A02991 | 34171931 | Z Gastroenterol | Conventional ultrasound for diagnosis of hepatic steatosis is better than believed. | 2021 | Details |
| A02992 | 34171492 | Pharmacol Res | Hepatic stellate cells role in the course of metabolic disorders development - A molecular overview. | 2021 | Details |
| A02994 | 34171418 | Food Chem Toxicol | Palmitoyl-CoA effect on cytochrome c release, a key process of apoptosis, from liver mitochondria of rat with sucrose diet-induced obesity. | 2021 | Details |
| A03004 | 34168277 | Int J Obes (Lond) | Performance of non-invasive fibrosis scores in non-alcoholic fatty liver disease with and without morbid obesity. | 2021 | Details |
| A03005 | 34168043 | BMJ Open Gastroenterol | Exercising in the COVID-19 era: implications in non-alcoholic fatty liver disease (NAFLD). | 2021 | Details |
| A03006 | 34167531 | BMC Surg | Bariatric surgery for non-alcoholic fatty liver disease in individuals with obesity (Base-NAFLD): protocol of a prospective multicenter observational follow-up study. | 2021 | Details |
| A03013 | 34164242 | Cureus | Role of Glucagon-Like Peptide-1 Receptor Agonists in the Management of Non-Alcoholic Steatohepatitis: A Clinical Review Article. | 2021 | Details |
| A03015 | 34163108 | World J Gastroenterol | Clinical indicators for progression of nonalcoholic steatohepatitis to cirrhosis. | 2021 | Details |
| A03017 | 34162749 | Sci Transl Med | Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis. | 2021 | Details |
| A03021 | 34160377 | Am J Gastroenterol | Fibrosis-4 Index vs Nonalcoholic Fatty Liver Disease Fibrosis Score in Identifying Advanced Fibrosis in Subjects With Nonalcoholic Fatty Liver Disease: A Meta-Analysis. | 2021 | Details |
| A03023 | 34160089 | J Gastroenterol Hepatol | Low skeletal muscle mass is associated with liver fibrosis in individuals with type 2 diabetes and nonalcoholic fatty liver disease. | 2021 | Details |
| A03027 | 34159442 | J Gastroenterol | STING and liver disease. | 2021 | Details |
| A03029 | 34159161 | Hepatobiliary Surg Nutr | Liver tissue microbiota in nonalcoholic liver disease: a change in the paradigm of host-bacterial interactions. | 2021 | Details |
| A03038 | 34155801 | Liver Int | Management of NAFLD patients with advanced fibrosis. | 2021 | Details |
| A03041 | 34155794 | Liver Int | New drugs for NASH. | 2021 | Details |
| A03042 | 34155792 | Liver Int | Natural history of NASH. | 2021 | Details |
| A03045 | 34155064 | Cancer Epidemiol Biomarkers Prev | Circulating Fatty Acids Associated with Advanced Liver Fibrosis and Hepatocellular Carcinoma in South Texas Hispanics. | 2021 | Details |
| A03047 | 34154037 | J Gastroenterol Hepatol | Liver fibrosis and fatty liver as independent risk factors for cardiovascular disease. | 2021 | Details |
| A03048 | 34153521 | Mol Metab | Neddylation inhibition ameliorates steatosis in NAFLD by boosting hepatic fatty acid oxidation via the DEPTOR-mTOR axis. | 2021 | Details |
| A03055 | 34152534 | Hepatol Int | Reduced hepatic steatosis is associated with higher risk of hepatocellular carcinoma in chronic hepatitis B infection. | 2021 | Details |
| A03058 | 34151243 | JHEP Rep | Aramchol downregulates stearoyl CoA-desaturase 1 in hepatic stellate cells to attenuate cellular fibrogenesis. | 2021 | Details |
| A03061 | 34147478 | Eur J Pharmacol | Sodium-glucose co-transporter 2 inhibitors in nonalcoholic fatty liver disease. | 2021 | Details |
| A03067 | 34144391 | Redox Biol | Proteasome dysfunction under compromised redox metabolism dictates liver injury in NASH through ASK1/PPARγ binodal complementary modules. | 2021 | Details |
| A03069 | 34142875 | Crit Rev Food Sci Nutr | Research progress on intervention effect and mechanism of protocatechuic acid on nonalcoholic fatty liver disease. | 2021 | Details |
| A03072 | 34141987 | Hepatol Commun | A Dynamic Aspartate-to-Alanine Aminotransferase Ratio Provides Valid Predictions of Incident Severe Liver Disease. | 2021 | Details |
| A03080 | 34139066 | Intern Med J | Towards collaborative management of nonalcoholic fatty liver disease (TCM-NAFLD): a 'real-world' pathway for fibrosis risk assessment in primary care. | 2021 | Details |
| A03084 | 34136664 | Biochem Biophys Rep | Consumption of barley ameliorates the diabetic steatohepatitis and reduces the high transforming growth factor β expression in mice grown in α-minimum essential medium in vitro as embryos. | 2021 | Details |
| A03085 | 34136549 | Front Cardiovasc Med | The Role of Lipid Profile as an Independent Predictor of Non-alcoholic Steatosis and Steatohepatitis in Morbidly Obese Patients. | 2021 | Details |
| A03086 | 34136497 | Front Med (Lausanne) | Metabolic Evaluation in Patients With Hepatitis C Treated With Direct Antiviral Agents. | 2021 | Details |
| A03089 | 34135776 | Front Physiol | Cytochrome P450 Omega-Hydroxylase 4a14 Attenuates Cholestatic Liver Fibrosis. | 2021 | Details |
| A03090 | 34135558 | World J Gastroenterol | Insight into molecular mechanisms underlying hepatic dysfunction in severe COVID-19 patients using systems biology. | 2021 | Details |
| A03091 | 34135151 | Indian J Pathol Microbiol | Liver biopsy in the quantitative assessment of liver fibrosis in nonalcoholic fatty liver disease. | 2021 | Details |
| A03093 | 34134495 | Cas Lek Cesk | Non-alcoholic fatty liver disease - how to effectively fight the nowadays most common liver disease? | 2021 | Details |
| A03096 | 34132935 | J Med Ultrason (2001) | Ultrasonographic grayscale findings related to fibrosis in patients with non-alcoholic fatty liver disease: comparison with transient elastography and Fib-4 index. | 2021 | Details |
| A03097 | 34132934 | J Med Ultrason (2001) | Quantitative assessment of liver steatosis using ultrasound controlled attenuation parameter (Echosens). | 2021 | Details |
| A03098 | 34132110 | Am J Physiol Gastrointest Liver Physiol | Surrogate scores of advanced fibrosis in NAFLD/NASH do not predict mortality in patients with medium-to-high cardiovascular risk. | 2021 | Details |
| A03099 | 34131471 | World J Hepatol | Combination of type IV collagen 7S, albumin concentrations, and platelet count predicts prognosis of non-alcoholic fatty liver disease. | 2021 | Details |
| A03110 | 34126247 | Endocr Pract | High Prevalence of Nonalcoholic Fatty Liver Disease Among Adolescents and Young Adults With Hypopituitarism due to Growth Hormone Deficiency. | 2021 | Details |
| A03111 | 34126105 | J Hepatol | Development and prognostic relevance of a histologic grading and staging system for alcohol-related liver disease. | 2021 | Details |
| A03113 | 34125886 | J Clin Endocrinol Metab | New Nonalcoholic Fatty Liver Disease and Fibrosis Progression Associate With the Risk of Incident Chronic Kidney Disease. | 2021 | Details |
| A03115 | 34124830 | Hepatol Res | Novel artificial intelligent/neural network system for staging of nonalcoholic steatohepatitis. | 2021 | Details |
| A03117 | 34123670 | Cureus | Effect of Dapagliflozin on Type 2 Diabetes Mellitus With Nonalcoholic Fatty Liver Disease: A Single-Center Survey. | 2021 | Details |
| A03119 | 34122138 | Front Physiol | Animal and Organoid Models of Liver Fibrosis. | 2021 | Details |
| A03127 | 34119629 | J Nutr Biochem | Sugar kelp (Saccharina latissima) inhibits hepatic inflammation and fibrosis in a mouse model of diet-induced nonalcoholic steatohepatitis. | 2021 | Details |
| A03128 | 34119474 | Am J Pathol | Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice. | 2021 | Details |
| A03129 | 34119399 | Acad Radiol | Comparison of the Effects of Hepatic Steatosis on Monoexponential DWI, Intravoxel Incoherent Motion Diffusion-weighted Imaging and Diffusion Kurtosis Imaging. | 2021 | Details |
| A03130 | 34118488 | Cell Mol Gastroenterol Hepatol | Fatty Acids Activate the Transcriptional Coactivator YAP1 to Promote Liver Fibrosis via p38 Mitogen-Activated Protein Kinase. | 2021 | Details |
| A03131 | 34118476 | Mol Metab | Exercise of high intensity ameliorates hepatic inflammation and the progression of NASH. | 2021 | Details |
| A03133 | 34118335 | J Hepatol | Prognostic performance of 7 biomarkers compared to liver biopsy in early alcohol-related liver disease. | 2021 | Details |
| A03135 | 34118091 | J Intern Med | Risk for hepatic and extra-hepatic outcomes in nonalcoholic fatty liver disease. | 2021 | Details |
| A03143 | 34114568 | Am J Gastroenterol | Fasting Ketonuria and the Risk of Incident Nonalcoholic Fatty Liver Disease With and Without Liver Fibrosis in Nondiabetic Adults. | 2021 | Details |
| A03161 | 34107545 | Semin Liver Dis | Gut-Liver Axis in Nonalcoholic Fatty Liver Disease: the Impact of the Metagenome, End Products, and the Epithelial and Vascular Barriers. | 2021 | Details |
| A03162 | 34107274 | Exp Cell Res | Lipid accumulation-induced hepatocyte senescence regulates the activation of hepatic stellate cells through the Nrf2-antioxidant response element pathway. | 2021 | Details |
| A03166 | 34106515 | Clin Obes | A clinical model to predict fibrosis on liver biopsy in paediatric subjects with nonalcoholic fatty liver disease. | 2021 | Details |
| A03167 | 34106414 | Cell Biochem Biophys | Thermally Oxidized Coconut Oil as Fat Source in High-Fat Diet Induces Hepatic Fibrosis in Diabetic Rat Model. | 2021 | Details |
| A03169 | 34105780 | Hepatology | Transcriptomics Identify Thrombospondin-2 as a Biomarker for NASH and Advanced Liver Fibrosis. | 2021 | Details |
| A03173 | 34101924 | Biofactors | alpha-Tocopherol supplementation reduces inflammation and apoptosis in high cholesterol mediated nonalcoholic steatohepatitis. | 2021 | Details |
| A03179 | 34098712 | Clin Mol Hepatol | Recent advances in nonalcoholic fatty liver disease metabolomics. | 2021 | Details |