Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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inflammatory5866 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A05294 | 33310034 | Life Sci | Aerobic training improves NAFLD markers and insulin resistance through AMPK-PPAR-α signaling in obese mice. | 2020 | Details |
| A05304 | 33308101 | Am J Chin Med | Antrodia Cinnamomea Attenuates Non-Alcoholic Steatohepatitis by Suppressing NLRP3 Inflammasome Activation In Vitro and In Vivo. | 2020 | Details |
| A05323 | 33302736 | Exp Biol Med (Maywood) | Characterizing disease progression of nonalcoholic steatohepatitis in Leptin-deficient rats by integrated transcriptome analysis. | 2020 | Details |
| A05326 | 33302316 | Horm Metab Res | Acute Elevated Resistin Exacerbates Mitochondrial Damage and Aggravates Liver Steatosis Through AMPK/PGC-1α Signaling Pathway in Male NAFLD Mice. | 2020 | Details |
| A05328 | 33301423 | J Clin Invest | Neutrophil-to-hepatocyte communication via LDLR-dependent miR-223-enriched extracellular vesicle transfer ameliorates nonalcoholic steatohepatitis. | 2021 | Details |
| A05331 | 33299871 | Biomed Res Int | Protective Role of Probiotic Supplements in Hepatic Steatosis: A Rat Model Study. | 2020 | Details |
| A05336 | 33298885 | Cell Death Dis | Hepatocyte cannabinoid 1 receptor nullification alleviates toxin-induced liver damage via NF-κB signaling. | 2020 | Details |
| A05340 | 33296704 | Diabetes Metab | NAFLD, and cardiovascular and cardiac diseases: Factors influencing risk, prediction and treatment. | 2020 | Details |
| A05342 | 33294831 | JHEP Rep | Macrophage-derived thrombospondin 1 promotes obesity-associated non-alcoholic fatty liver disease. | 2020 | Details |
| A05344 | 33293992 | Evid Based Complement Alternat Med | Effect of Sheng-Jiang Powder on Gut Microbiota in High-Fat Diet-Induced NAFLD. | 2020 | Details |
| A05346 | 33292701 | Biomark Res | Dysregulated bile acid receptor-mediated signaling and IL-17A induction are implicated in diet-associated hepatic health and cognitive function. | 2020 | Details |
| A05351 | 33290156 | Can J Physiol Pharmacol | Theobromine ameliorates nonalcoholic fatty liver disease by regulating hepatic lipid metabolism via mTOR signaling pathway in vivo and in vitro. | 2020 | Details |
| A05353 | 33289147 | J Food Biochem | A high-fructose diet in rats induces systemic iron deficiency and hepatic iron overload by an inflammation mechanism. | 2020 | Details |
| A05357 | 33283879 | J Cell Physiol | Endogenous metabolite, kynurenic acid, attenuates nonalcoholic fatty liver disease via AMPK/autophagy- and AMPK/ORP150-mediated signaling. | 2020 | Details |
| A05360 | 33282902 | Front Nutr | Maternal High-Fat Diet Leads to Non-alcoholic Fatty Liver Disease Through Upregulating Hepatic SCD1 Expression in Neonate Rats. | 2020 | Details |
| A05364 | 33281770 | Front Microbiol | Novel Odoribacter splanchnicus Strain and Its Outer Membrane Vesicles Exert Immunoregulatory Effects in vitro. | 2020 | Details |
| A05388 | 33273997 | Oxid Med Cell Longev | Plant Sterol Ester of α-Linolenic Acid Attenuates Nonalcoholic Fatty Liver Disease by Rescuing the Adaption to Endoplasmic Reticulum Stress and Enhancing Mitochondrial Biogenesis. | 2019 | Details |
| A05393 | 33272734 | Gastroenterol Hepatol | Silencing HIF-1α aggravates non-alcoholic fatty liver disease in vitro through inhibiting PPAR-α/ANGPTL4 singling pathway. | 2020 | Details |
| A05396 | 33271781 | Int J Mol Sci | Two-Week Isocaloric Time-Restricted Feeding Decreases Liver Inflammation without Significant Weight Loss in Obese Mice with Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05410 | 33268887 | Cell Mol Immunol | Immunological mechanisms and therapeutic targets of fatty liver diseases. | 2020 | Details |
| A05413 | 33268509 | Sci Transl Med | Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis. | 2020 | Details |
| A05414 | 33268508 | Sci Transl Med | Glycine-based treatment ameliorates NAFLD by modulating fatty acid oxidation, glutathione synthesis, and the gut microbiome. | 2020 | Details |
| A05426 | 33260679 | Nutrients | The Dietary Replacement of Soybean Oil by Canola Oil Does Not Prevent Liver Fatty Acid Accumulation and Liver Inflammation in Mice. | 2020 | Details |
| A05429 | 33260239 | Horm Metab Res | The Role of Brown Adipose Tissue in the Development and Treatment of Nonalcoholic Steatohepatitis: An Exploratory Gene Expression Study in Mice. | 2020 | Details |
| A05447 | 33253604 | Pharm Biol | Effects of wogonoside on the inflammatory response and oxidative stress in mice with nonalcoholic fatty liver disease. | 2020 | Details |
| A05457 | 33249742 | Mol Nutr Food Res | Catechin-Rich Green Tea Extract and the Loss-of-TLR4 Signaling Differentially Alter the Hepatic Metabolome in Mice with Nonalcoholic Steatohepatitis. | 2020 | Details |
| A05462 | 33248947 | Arch Biochem Biophys | The pivotal role of heme Oxygenase-1 in reversing the pathophysiology and systemic complications of NAFLD. | 2020 | Details |
| A05465 | 33248168 | J Hepatol | Acetylation of lactate dehydrogenase B drives NAFLD progression by impairing lactate clearance. | 2020 | Details |
| A05481 | 33240906 | Front Med (Lausanne) | CML/RAGE Signal Bridges a Common Pathogenesis Between Atherosclerosis and Non-alcoholic Fatty Liver. | 2020 | Details |
| A05493 | 33234364 | Phytomedicine | Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe-/-mice: role of SIRT1. | 2020 | Details |
| A05500 | 33228663 | J Transl Med | LncRNA NEAT1/microRNA-129-5p/SOCS2 axis regulates liver fibrosis in alcoholic steatohepatitis. | 2020 | Details |
| A05504 | 33227291 | Biochem Pharmacol | Aryl hydrocarbon receptor (AHR), integrating energy metabolism and microbial or obesity-mediated inflammation. | 2020 | Details |
| A05528 | 33218077 | Int J Mol Sci | PNPLA3 I148M Up-Regulates Hedgehog and Yap Signaling in Human Hepatic Stellate Cells. | 2020 | Details |
| A05536 | 33215899 | Transplantation | Live Confocal Imaging as a Novel Tool to Assess Liver Quality: Insights From a Murine Model. | 2020 | Details |
| A05546 | 33212947 | Nutrients | Fructose, Omega 3 Fatty Acids, and Vitamin E: Involvement in Pediatric Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05547 | 33212187 | Biochim Biophys Acta Mol Basis Dis | Vesicular ATP release from hepatocytes plays a role in the progression of nonalcoholic steatohepatitis. | 2020 | Details |
| A05549 | 33211913 | Vopr Pitan | [Effect of carnosine and α-lipoic acid on hepatocyte apoptosis and the cytokine profile in induced fatty liver disease in Wistar rats]. | 2020 | Details |
| A05568 | 33204402 | Oxid Med Cell Longev | Chicoric Acid Ameliorates Nonalcoholic Fatty Liver Disease via the AMPK/Nrf2/NFκB Signaling Pathway and Restores Gut Microbiota in High-Fat-Diet-Fed Mice. | 2020 | Details |
| A05569 | 33203939 | Cell Mol Immunol | Immunopathobiology and therapeutic targets related to cytokines in liver diseases. | 2020 | Details |
| A05570 | 33203828 | Med Sci Monit | Altered Inflammatory Pathway but Unaffected Liver Fibrosis in Mouse Models of Nonalcoholic Steatohepatitis Involving Interleukin-1 Receptor-Associated Kinase 1 Knockout. | 2020 | Details |
| A05571 | 33203257 | Int J Food Sci Nutr | Hepatoprotective and anti-inflammatory effects of a standardized pomegranate (Punica granatum) fruit extract in high fat diet-induced obese C57BL/6 mice. | 2020 | Details |
| A05576 | 33202693 | Int J Mol Sci | IL-18 but Not IL-1 Signaling Is Pivotal for the Initiation of Liver Injury in Murine Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05603 | 33193105 | Front Endocrinol (Lausanne) | Can You Trust Your Gut? Implicating a Disrupted Intestinal Microbiome in the Progression of NAFLD/NASH. | 2020 | Details |
| A05628 | 33183606 | Carbohydr Polym | Friend or foe? The roles of inulin-type fructans. | 2020 | Details |
| A05632 | 33182038 | Int Immunopharmacol | Resolvin D1 mitigates non-alcoholic steatohepatitis by suppressing the TLR4-MyD88-mediated NF-κB and MAPK pathways and activating the Nrf2 pathway in mice. | 2020 | Details |
| A05635 | 33180143 | Eur J Nutr | A bridge for short-chain fatty acids to affect inflammatory bowel disease, type 1 diabetes, and non-alcoholic fatty liver disease positively: by changing gut barrier. | 2020 | Details |
| A05642 | 33177790 | World J Gastroenterol | Role of gut microbiota via the gut-liver-brain axis in digestive diseases. | 2020 | Details |
| A05645 | 33177546 | Sci Rep | PPARα agonist and metformin co-treatment ameliorates NASH in mice induced by a choline-deficient, amino acid-defined diet with 45% fat. | 2020 | Details |
| A05646 | 33176658 | Curr Diabetes Rev | Dipeptidyl Peptidase IV Inhibitors for Nonalcoholic Fatty Liver Disease - Systematic Review and Metanalysis. | 2021 | Details |
| A05648 | 33173850 | SN Compr Clin Med | NAFLD and COVID-19: a Pooled Analysis. | 2020 | Details |
| A05651 | 33172809 | Dig Liver Dis | Leptin induces NAFLD progression through infiltrated CD8+ T lymphocytes mediating pyroptotic-like cell death of hepatocytes and macrophages. | 2020 | Details |
| A05657 | 33171266 | Transl Res | Nonalcoholic fatty liver disease (NAFLD) severity is associated to a nonhemostatic contribution and proinflammatory phenotype of platelets. | 2020 | Details |
| A05663 | 33168782 | Aging (Albany NY) | Human mesenchymal stem cells treatment improved hepatic lesions and reversed gut microbiome disorder in non-alcoholic steatohepatitis. | 2020 | Details |
| A05666 | 33167328 | Int J Mol Sci | 9-PAHSA Prevents Mitochondrial Dysfunction and Increases the Viability of Steatotic Hepatocytes. | 2020 | Details |
| A05668 | 33166032 | Phytother Res | Protective effects of propolis on hepatic steatosis and fibrosis among patients with nonalcoholic fatty liver disease (NAFLD) evaluated by real-time two-dimensional shear wave elastography: A randomized clinical trial. | 2020 | Details |
| A05674 | 33164398 | Zhongguo Zhong Yao Za Zhi | [Mechanism of Alisma orientale in treating nonalcoholic fatty liver disease]. | 2020 | Details |
| A05678 | 33163831 | Hepatol Commun | Loss of Hepatic Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Links Nonalcoholic Steatohepatitis to Atherosclerosis. | 2020 | Details |
| A05680 | 33162737 | Ann Gastroenterol | Nonalcoholic fatty liver disease and atrial fibrillation: possible pathophysiological links and therapeutic interventions. | 2020 | Details |
| A05703 | 33149804 | Oxid Med Cell Longev | Role of Oxidative Stress in Hepatic and Extrahepatic Dysfunctions during Nonalcoholic Fatty Liver Disease (NAFLD). | 2020 | Details |
| A05717 | 33143903 | Pathology | Electron microscopic observations in perfusion-fixed human non-alcoholic fatty liver disease biopsies. | 2020 | Details |
| A05725 | 33142714 | J Clin Med | Associations of HDL Subspecies Defined by ApoC3 with Non-Alcoholic Fatty Liver Disease: The Multi-Ethnic Study of Atherosclerosis. | 2020 | Details |
| A05728 | 33142346 | Planta Med | Brown-Algae Polysaccharides as Active Constituents against Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A05742 | 33135718 | Food Funct | Integrative transcriptomics and metabolomics explore the mechanism of kaempferol on improving nonalcoholic steatohepatitis. | 2020 | Details |
| A05755 | 33132309 | Biol Pharm Bull | Protective Effect of Fuzi Lizhong Decoction against Non-alcoholic Fatty Liver Disease via Anti-inflammatory Response through Regulating p53 and PPARG Signaling. | 2020 | Details |
| A05759 | 33131062 | Hepatology | Identification of a Metabolic, Transcriptomic, and Molecular Signature of Patatin-Like Phospholipase Domain Containing 3-Mediated Acceleration of Steatohepatitis. | 2021 | Details |
| A05767 | 33126575 | Nutrients | Vitamin D and Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD): An Update. | 2020 | Details |
| A05780 | 33121337 | Cell Cycle | Gypenosides improves nonalcoholic fatty liver disease induced by high-fat diet induced through regulating LPS/TLR4 signaling pathway. | 2020 | Details |
| A05787 | 33117273 | Front Endocrinol (Lausanne) | Palmitoleic Acid Decreases Non-alcoholic Hepatic Steatosis and Increases Lipogenesis and Fatty Acid Oxidation in Adipose Tissue From Obese Mice. | 2020 | Details |
| A05791 | 33116702 | Diabetes Metab Syndr Obes | Effect of Saxagliptin, a Dipeptidyl Peptidase 4 Inhibitor, on Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A05792 | 33115780 | Cancer Prev Res (Phila) | Targeting the Cholecystokinin Receptor: A Novel Approach for Treatment and Prevention of Hepatocellular Cancer. | 2020 | Details |
| A05795 | 33114564 | Nutrients | Protective Effects of (E)-β-Caryophyllene (BCP) in Chronic Inflammation. | 2020 | Details |
| A05798 | 33114299 | Antioxidants (Basel) | Comparative Effects of Pterostilbene and Its Parent Compound Resveratrol on Oxidative Stress and Inflammation in Steatohepatitis Induced by High-Fat High-Fructose Feeding. | 2020 | Details |
| A05801 | 33114221 | Antioxidants (Basel) | Auranofin Attenuates Non-Alcoholic Fatty Liver Disease by Suppressing Lipid Accumulation and NLRP3 Inflammasome-Mediated Hepatic Inflammation In Vivo and In Vitro. | 2020 | Details |
| A05804 | 33113993 | Nutrients | Effects of a Low Dose of Caffeine Alone or as Part of a Green Coffee Extract, in a Rat Dietary Model of Lean Non-Alcoholic Fatty Liver Disease without Inflammation. | 2020 | Details |
| A05819 | 33106416 | Proc Natl Acad Sci U S A | Stimulation of soluble guanylate cyclase exerts antiinflammatory actions in the liver through a VASP/NF-κB/NLRP3 inflammasome circuit. | 2020 | Details |
| A05820 | 33106141 | Curr Mol Med | Critical Role of NFκB in the Pathogenesis of Non-alcoholic Fatty Liver Disease: A Widespread Key Regulator. | 2021 | Details |
| A05821 | 33106137 | Curr Pharm Des | Therapeutic effect of Prdx1 on NAFLD mice may be related to the activation of Nrf-2/HO-1 pathway. | 2020 | Details |
| A05826 | 33105887 | Biology (Basel) | Lauric Acid versus Palmitic Acid: Effects on Adipose Tissue Inflammation, Insulin Resistance, and Non-Alcoholic Fatty Liver Disease in Obesity. | 2020 | Details |
| A05828 | 33105604 | Int J Mol Sci | Linagliptin Ameliorates Hepatic Steatosis via Non-Canonical Mechanisms in Mice Treated with a Dual Inhibitor of Insulin Receptor and IGF-1 Receptor. | 2020 | Details |
| A05830 | 33104787 | Phys Ther | Determinants of Physical Activity Engagement in Patients With Nonalcoholic Fatty Liver Disease: The Need for an Individualized Approach to Lifestyle Interventions. | 2021 | Details |
| A05850 | 33102138 | Toxicol Rep | Welding fume inhalation exposure and high-fat diet change lipid homeostasis in rat liver. | 2020 | Details |
| A05866 | 33096076 | Metabolism | Pharmacological activation of REV-ERBα improves nonalcoholic steatohepatitis by regulating intestinal permeability. | 2020 | Details |
| A05869 | 33095225 | Food Funct | Green tea polyphenol epigallocatechin-3-gallate alleviates nonalcoholic fatty liver disease and ameliorates intestinal immunity in mice fed a high-fat diet. | 2020 | Details |
| A05872 | 33093663 | Nat Rev Gastroenterol Hepatol | Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors. | 2020 | Details |
| A05894 | 33084982 | Acta Diabetol | Association of 1-deoxy-sphingolipids with steatosis but not steatohepatitis nor fibrosis in non-alcoholic fatty liver disease. | 2020 | Details |
| A05914 | 33077425 | Drug Metab Dispos | Histone Methyltransferase G9a Regulates Expression of Nuclear Receptors and Cytochrome P450 Enzymes in HepaRG Cells at Basal Level and in Fatty Acid Induced Steatosis. | 2020 | Details |
| A05916 | 33076582 | Life (Basel) | Quercitrin Ameliorates Hyperlipidemia and Hepatic Steatosis in Ovariectomized Mice. | 2020 | Details |
| A05924 | 33074035 | Expert Opin Investig Drugs | The nonalcoholic steatohepatitis (NASH) drug development graveyard: established hurdles and planning for future success. | 2020 | Details |
| A05927 | 33073044 | Transl Gastroenterol Hepatol | Pathogenesis and pathways: nonalcoholic fatty liver disease & alcoholic liver disease. | 2020 | Details |
| A05931 | 33072455 | Cureus | Pleiotropic Effects of Statins in the Light of Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A05934 | 33071979 | Front Endocrinol (Lausanne) | Non-alcoholic Fatty Liver Disease as a Canonical Example of Metabolic Inflammatory-Based Liver Disease Showing a Sex-Specific Prevalence: Relevance of Estrogen Signaling. | 2020 | Details |
| A05936 | 33071788 | Front Pharmacol | Veratrilla baillonii Franch Could Alleviate Lipid Accumulation in LO2 Cells by Regulating Oxidative, Inflammatory, and Lipid Metabolic Signaling Pathways. | 2020 | Details |
| A05946 | 33067533 | Sci Rep | HFD-induced hepatic lipid accumulation and inflammation are decreased in Factor D deficient mouse. | 2020 | Details |
| A05949 | 33066113 | Int J Mol Sci | Chymase as a Possible Therapeutic Target for Amelioration of Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A05959 | 33061687 | Hepat Med | Efficacy of Glucagon-Like Peptide-1 Analogs in Nonalcoholic Fatty Liver Disease: A Systematic Review. | 2020 | Details |
| A05960 | 33061293 | Drug Des Devel Ther | Phoenixin 14 Inhibits High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Experimental Mice. | 2020 | Details |
| A05974 | 33055315 | Rom J Intern Med | Association between serum interleukin (IL)-12 level and severity of non-alcoholic fatty liver disease (NAFLD). | 2021 | Details |
| A05985 | 33050862 | Curr Pharm Biotechnol | Engineered Probiotic and Prebiotic Nutraceutical Supplementations in Combating Non-communicable Disorders: A Review. | 2022 | Details |
| A05986 | 33050482 | Int J Mol Sci | Early Pro-Inflammatory Remodeling of HDL Proteome in a Model of Diet-Induced Obesity: 2H2O-Metabolic Labeling-Based Kinetic Approach. | 2020 | Details |
| A05987 | 33050138 | Biomedicines | Tissue-Specific Role of Macrophages in Noninfectious Inflammatory Disorders. | 2020 | Details |