Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Article ID | PMID | Source | Title | Publish Year | |
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A46591 | 17408630 | Gastroenterology | The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells. | 2007 | Details |
A46592 | 17407723 | Zhonghua Gan Zang Bing Za Zhi | [Changes of liver fibrosis markers in nonalcoholic fatty liver disease patients]. | 2007 | Details |
A46602 | 17355088 | Semin Diagn Pathol | Alcoholic liver disease. | 2007 | Details |
A46612 | 17296533 | Clin Gastroenterol Hepatol | Hepatic steatosis in hepatitis C: comparison of diabetic and nondiabetic patients in the hepatitis C antiviral long-term treatment against cirrhosis trial. | 2007 | Details |
A46617 | 17268250 | Curr Opin Gastroenterol | Fatty liver and the metabolic syndrome. | 2007 | Details |
A46623 | 17219068 | Dig Dis Sci | The effect of a low-carbohydrate, ketogenic diet on nonalcoholic fatty liver disease: a pilot study. | 2007 | Details |
A46627 | 17160239 | Arq Gastroenterol | Prevalence of the hemochromatosis gene mutation in patients with nonalcoholic steatohepatitis and correlation with degree of liver fibrosis. | 2007 | Details |
A46633 | 28381952 | Gastroenterol Hepatol (N Y) | The Treatment of Hepatic Fibrosis: Reversal of the Underlying Disease Process. | 2006 | Details |
A46642 | 16952281 | Am J Gastroenterol | The evolving role of leptin and adiponectin in chronic liver diseases. | 2006 | Details |
A46666 | 16762000 | Liver Int | Differential findings for CD14-positive hepatic monocytes/macrophages in primary biliary cirrhosis, chronic hepatitis C and nonalcoholic steatohepatitis. | 2006 | Details |
A46669 | 16729327 | Hepatology | Impact of obesity on treatment of chronic hepatitis C. | 2006 | Details |
A46680 | 16584696 | Gastroenterol Hepatol | [Epidemiology and natural history of primary nonalcoholic fatty liver disease]. | 2006 | Details |
A46684 | 16550033 | Curr Opin Gastroenterol | Hepatobiliary pathology. | 2006 | Details |
A46690 | 16510031 | Curr Gastroenterol Rep | New treatments for nonalcoholic fatty liver disease. | 2006 | Details |
A46694 | 16471264 | J Soc Biol | [Experimental modulation of apoptosis: physiopathological and therapeutic targets]. | 2005 | Details |
A46704 | 16369215 | Rev Gastroenterol Disord | Role of liver biopsy in the management of chronic liver disease: selective rather than routine. | 2005 | Details |
A46715 | 16265231 | Nat Clin Pract Gastroenterol Hepatol | Mechanisms of disease: adipocytokines and visceral adipose tissue--emerging role in nonalcoholic fatty liver disease. | 2005 | Details |
A46720 | 16234011 | Clin Gastroenterol Hepatol | Diagnostic value of quantitative hepatic copper determination in patients with Wilson's Disease. | 2005 | Details |
A46726 | 16175602 | Hepatology | Steatohepatitis induced by intragastric overfeeding in mice. | 2005 | Details |
A46731 | 16137470 | Gastroenterol Hepatol | [Nonalcoholic steatohepatitis associated with ovarian stromal hyperplasia]. | 2005 | Details |
A46736 | 16083334 | Expert Opin Emerg Drugs | Nonalcoholic fatty liver disease: a review. | 2005 | Details |
A46741 | 15990637 | J Pediatr Gastroenterol Nutr | Type 2 diabetes in children is frequently associated with elevated alanine aminotransferase. | 2005 | Details |
A46742 | 15990591 | Curr Opin Lipidol | Nonalcoholic fatty liver disease and the metabolic syndrome. | 2005 | Details |
A46746 | 15977205 | Hepatology | Morbid obesity, nonalcoholic fatty liver disease, and weight loss surgery. | 2005 | Details |
A46755 | 15882516 | Med Clin (Barc) | [Pathogenesis of primary nonalcoholic fatty liver disease]. | 2005 | Details |
A46763 | 15763233 | Clin Liver Dis | Long-term management of alcoholic liver disease. | 2005 | Details |
A46765 | 15730035 | Ned Tijdschr Geneeskd | [Nonalcoholic steatohepatitis: diagnosis, pathogenesis, treatment and prognosis]. | 2005 | Details |
A46766 | 15728360 | Proc Natl Acad Sci U S A | Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma. | 2005 | Details |
A46775 | 15682682 | J Investig Med | Oxidative stress in nonalcoholic fatty liver disease: pathogenesis and antioxidant therapies. | 2004 | Details |
A46776 | 15670659 | Alcohol | Role of fatty liver, dietary fatty acid supplements, and obesity in the progression of alcoholic liver disease: introduction and summary of the symposium. | 2004 | Details |
A46784 | 15605304 | Semin Liver Dis | Liver pathology in obesity. | 2004 | Details |
A46786 | 15578508 | Gastroenterology | Serum markers detect the presence of liver fibrosis: a cohort study. | 2004 | Details |
A46792 | 15508109 | Gastroenterology | Obesity and hepatocellular carcinoma. | 2004 | Details |
A46795 | 15382171 | Hepatology | Natural history of nonalcoholic steatohepatitis: a longitudinal study of repeat liver biopsies. | 2004 | Details |
A46810 | 15086699 | Intern Med J | Nonalcoholic fatty liver disease: is all the fat bad? | 2004 | Details |
A46816 | 14752843 | Hepatology | Vascular involvement of the liver in Turner's syndrome. | 2004 | Details |
A46818 | 14720455 | Curr Gastroenterol Rep | New concepts of the pathogenesis of alcoholic liver disease lead to novel treatments. | 2004 | Details |
A46821 | 14687145 | Am J Gastroenterol | Cognitive lifetime drinking history in nonalcoholic fatty liver disease: some cases may be alcohol related. | 2004 | Details |
A46827 | 14507639 | Am J Pathol | Oxidative stress and oval cell accumulation in mice and humans with alcoholic and nonalcoholic fatty liver disease. | 2003 | Details |
A46833 | 12957298 | Alcohol | Iron as a co-morbid factor in nonhemochromatotic liver disease. | 2003 | Details |
A46834 | 12920429 | Gastroenterol Nurs | Nonalcoholic Fatty liver disease. | 2003 | Details |
A46837 | 12881873 | Zhejiang Da Xue Xue Bao Yi Xue Ban | [Liver fibrosis indexes in nonalcoholic fatty liver disease]. | 2003 | Details |
A46839 | 12828075 | Hepatogastroenterology | Serum ubiquitin levels in patients with nonalcoholic steatohepatitis. | 2003 | Details |
A46856 | 12527713 | Mod Pathol | Concurrence of histologic features of steatohepatitis with other forms of chronic liver disease. | 2003 | Details |
A46859 | 12417056 | J Cell Mol Med | Oxidative stress in the pathogenesis of nonalcoholic fatty liver disease, in rats fed with a choline-deficient diet. | 2003 | Details |
A46860 | 12408779 | Curr Treat Options Gastroenterol | Therapeutic Options in Nonalcoholic Fatty Liver Disease. | 2002 | Details |
A46863 | 12235896 | Rev Med Chil | [Obesity: risk factor for steatohepatitis and hepatic fibrosis]. | 2002 | Details |
A46880 | 11825540 | Curr Gastroenterol Rep | Use of ursodeoxycholic acid in patients with liver disease. | 2002 | Details |
A46882 | 11755315 | Free Radic Biol Med | Lipid peroxidation contributes to immune reactions associated with alcoholic liver disease. | 2002 | Details |
A46899 | 10811531 | Cell Biol Toxicol | Hepatotoxicity due to mitochondrial dysfunction. | 1999 | Details |
A46905 | 34970275 | Front Immunol | Macrophage Polarization and Its Role in Liver Disease. | 2021 | Details |
A46908 | 34817678 | Eur J Nutr | Betaine in ameliorating alcohol-induced hepatic steatosis. | 2021 | Details |
A46910 | 34646717 | Alcohol Res | Hepatic Cannabinoid Signaling in the Regulation of Alcohol-Associated Liver Disease. | 2021 | Details |
A46911 | 34558087 | Alcohol Clin Exp Res | A review of the role of ethanol-induced adipose tissue dysfunction in alcohol-associated liver disease. | 2021 | Details |
A46913 | 34523155 | Alcohol Clin Exp Res | A Western diet with alcohol in drinking water recapitulates features of alcohol-associated liver disease in mice. | 2021 | Details |
A46915 | 34428307 | Aliment Pharmacol Ther | Progressive alcohol-related liver fibrosis is characterised by imbalanced collagen formation and degradation. | 2021 | Details |
A46921 | 34229840 | Clin Liver Dis | Diagnosis of Alcohol-Associated Hepatitis: When Is Liver Biopsy Required? | 2021 | Details |
A46925 | 34068838 | Nutrients | Markers of Intestinal Permeability Are Rapidly Improved by Alcohol Withdrawal in Patients with Alcohol-Related Liver Disease. | 2021 | Details |
A46926 | 34066517 | Cells | Chronic Alcohol Exposure of Cells Using Controlled Alcohol-Releasing Capillaries. | 2021 | Details |
A46930 | 33860120 | Hepatol Commun | Clinical Presentation and Gene Expression of Acute Alcohol-Induced Microvesicular Steatosis Mimicking Alcoholic Hepatitis. | 2021 | Details |
A46933 | 33713857 | Biochem Biophys Res Commun | Mesencephalic astrocyte-derived neurotrophic factor alleviates alcohol induced hepatic steatosis via activating Stat3-mediated autophagy. | 2021 | Details |
A46936 | 33598648 | JHEP Rep | Gut dysbiosis as a driver in alcohol-induced liver injury. | 2020 | Details |
A46940 | 33443222 | Proc Natl Acad Sci U S A | Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22. | 2020 | Details |
A46945 | 33162823 | Int J Biol Sci | Emerging Roles of SIRT1 in Alcoholic Liver Disease. | 2020 | Details |
A46946 | 33132639 | World J Gastroenterol | Longitudinal decrease in platelet counts as a surrogate marker of liver fibrosis. | 2020 | Details |
A46949 | 32960884 | PLoS Comput Biol | Alcoholic liver disease: A registry view on comorbidities and disease prediction. | 2020 | Details |
A46952 | 32790342 | ACS Nano | Luminescence Imaging of Acute Liver Injury by Biodegradable and Biocompatible Nanoprobes. | 2020 | Details |
A46966 | 32087348 | J Hepatol | Hepatic stellate cell activation promotes alcohol-induced steatohepatitis through Igfbp3 and SerpinA12. | 2020 | Details |
A46978 | 31491888 | Biomedicines | Alcoholic Liver Disease: Current Mechanistic Aspects with Focus on Their Clinical Relevance. | 2019 | Details |
A46983 | 31321478 | J Mol Med (Berl) | S100A4 promotes inflammation but suppresses lipid accumulation via the STAT3 pathway in chronic ethanol-induced fatty liver. | 2019 | Details |
A46988 | 31173814 | J Hepatol | Natural history of histologically proven alcohol-related liver disease: A systematic review. | 2019 | Details |
A46999 | 30773529 | Med Sci Monit | Evaluation of Relationship between Occurrence of Liver Cancer and Methylation of Fragile Histidine Triad (FHIT) and P16 Genes. | 2019 | Details |
A47003 | 30658728 | J Hepatol | Non-invasive diagnosis and biomarkers in alcohol-related liver disease. | 2019 | Details |
A47006 | 30256818 | PLoS One | Ethanol and unsaturated dietary fat induce unique patterns of hepatic ω-6 and ω-3 PUFA oxylipins in a mouse model of alcoholic liver disease. | 2018 | Details |
A47007 | 30248395 | Alcohol | Pharmacokinetic changes of tramadol in rats with hepatotoxicity induced by ethanol and acetaminophen in perfused rat liver model. | 2018 | Details |
A47009 | 30179264 | Hepatology | Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol-Induced Liver Damage, Steatosis, and Inflammation in Mice. | 2019 | Details |
A47011 | 30115921 | Nat Rev Dis Primers | Alcoholic liver disease. | 2018 | Details |
A47013 | 30071471 | Redox Biol | Pomegranate prevents binge alcohol-induced gut leakiness and hepatic inflammation by suppressing oxidative and nitrative stress. | 2018 | Details |
A47014 | 30048873 | Drug Alcohol Depend | Ultrasound findings of liver damage in a series of patients consecutively admitted for treatment of alcohol use disorder. | 2018 | Details |
A47016 | 29852391 | Biomed Pharmacother | Increased hepatic FAT/CD36, PTP1B and decreased HNF4A expression contributes to dyslipidemia associated with ethanol-induced liver dysfunction: Rescue effect of ginger extract. | 2018 | Details |
A47035 | 28689299 | J Mol Med (Berl) | 4-O'-methylhonokiol protects from alcohol/carbon tetrachloride-induced liver injury in mice. | 2017 | Details |
A47041 | 28467182 | Exp Biol Med (Maywood) | Roles of silent information regulator 1-serine/arginine-rich splicing factor 10-lipin 1 axis in the pathogenesis of alcohol fatty liver disease. | 2017 | Details |
A47043 | 28274894 | J Ethnopharmacol | Effects of antrosterol from Antrodia camphorata submerged whole broth on lipid homeostasis, antioxidation, alcohol clearance, and anti-inflammation in livers of chronic-alcohol fed mice. | 2017 | Details |
A47045 | 28134813 | Biomolecules | Key Events Participating in the Pathogenesis of  Alcoholic Liver Disease. | 2017 | Details |
A47046 | 28112200 | Sci Rep | Reduction of hepatic fibrosis by overexpression of von Hippel-Lindau protein in experimental models of chronic liver disease. | 2017 | Details |
A47049 | 27871879 | J Hepatol | Aging aggravates alcoholic liver injury and fibrosis in mice by downregulating sirtuin 1 expression. | 2016 | Details |
A47052 | 27824131 | Sci Rep | Infliximab and Dexamethasone Attenuate the Ductular Reaction in Mice. | 2016 | Details |
A47058 | 27630043 | Nat Commun | MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C. | 2016 | Details |
A47061 | 27404390 | Sci Rep | Suppression of PPARγ-mediated monoacylglycerol O-acyltransferase 1 expression ameliorates alcoholic hepatic steatosis. | 2016 | Details |
A47069 | 26934429 | Cochrane Database Syst Rev | Ultrasonography for diagnosis of alcoholic cirrhosis in people with alcoholic liver disease. | 2016 | Details |
A47081 | 26576483 | J Hepatol | Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease. | 2015 | Details |
A47084 | 26511776 | Alcohol Alcohol | The Role of Ceramide in the Pathogenesis of Alcoholic Liver Disease. | 2015 | Details |
A47086 | 26494961 | World J Gastroenterol | Non-invasive assessment of liver fibrosis in patients with alcoholic liver disease. | 2015 | Details |
A47088 | 26459052 | Int Immunopharmacol | Ligustrazine prevents alcohol-induced liver injury by attenuating hepatic steatosis and oxidative stress. | 2015 | Details |
A47093 | 26099526 | Gastroenterology | Fat-Specific Protein 27/CIDEC Promotes Development of Alcoholic Steatohepatitis in Mice and Humans. | 2015 | Details |
A47097 | 26025474 | Biochimie | Excessive bile acid activated NF-kappa B and promoted the development of alcoholic steatohepatitis in farnesoid X receptor deficient mice. | 2015 | Details |
A47100 | 25923904 | Zebrafish | Development of an Animal Model for Alcoholic Liver Disease in Zebrafish. | 2015 | Details |
A47108 | 25872593 | Alcohol Clin Exp Res | Alcoholic liver disease: the gut microbiome and liver cross talk. | 2015 | Details |
A47109 | 25869468 | J Hepatobiliary Pancreat Sci | Recent advancement of molecular mechanisms of liver fibrosis. | 2015 | Details |
A47114 | 25717264 | World J Gastroenterol | Autoimmune hepatitis-primary biliary cirrhosis concurrent with biliary stricture after liver transplantation. | 2015 | Details |