Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A47530 | 3950364 | J Hepatol | Benign bile duct tumours, non-parasitic liver cysts and liver damage in males. | 1986 | Details |
| A47531 | 2873160 | J Am Coll Nutr | Control of polyunsaturated acids in tissue lipids. | 1986 | Details |
| A47532 | 4043669 | Gastroenterology | Increased type I procollagen mRNA levels and in vitro protein synthesis in the baboon model of chronic alcoholic liver disease. | 1985 | Details |
| A47534 | 4009897 | JAMA | Perivenular fibrosis as precursor lesion of cirrhosis. | 1985 | Details |
| A47542 | 4059796 | Ric Clin Lab | Procollagen-type III peptide serum concentrations in alcoholic and non-alcoholic liver disease. | 1985 | Details |
| A47543 | 3996813 | Gastroenterol Clin Biol | [Latent myocardiopathy in chronic alcoholic patients with or without hepatic involvement]. | 1985 | Details |
| A47549 | 3964762 | Gastroenterology | Pathogenesis of precirrhotic portal hypertension in alcohol-fed baboons. | 1985 | Details |
| A47554 | 6479851 | Hepatology | The N-terminal propeptide of collagen type III in serum reflects activity and degree of fibrosis in patients with chronic liver disease. | 1984 | Details |
| A47557 | 6745860 | Hepatology | Correlation between liver morphology and portal pressure in alcoholic liver disease. | 1984 | Details |
| A47559 | 6385761 | Alcohol Clin Exp Res | Diagnostic value of serum procollagen peptide measurements in alcoholic liver disease. | 1984 | Details |
| A47561 | 6610087 | Liver | Cellular cytotoxicity against autologous hepatocytes in alcoholic liver disease. | 1984 | Details |
| A47563 | 6538546 | Hepatology | Biochemical and morphological alterations of baboon hepatic mitochondria after chronic ethanol consumption. | 1984 | Details |
| A47564 | 6199263 | Gut | Antibodies to alcohol altered liver cell determinants in patients with alcoholic liver disease. | 1984 | Details |
| A47566 | 6595976 | Arch Toxicol Suppl | Changes in germinal tissue and Leydig cells correlated with ethanol consumption in males with and without liver disease. | 1984 | Details |
| A47577 | 6604608 | Clin Exp Immunol | Lymphocyte cytotoxicity for autologous human hepatocytes in alcoholic liver disease. | 1983 | Details |
| A47580 | 6688340 | Arch Pathol Lab Med | The role of the Ito cell in perivenular and intralobular fibrosis in alcoholic hepatitis. | 1983 | Details |
| A47600 | 6129080 | Clin Chim Acta | gamma-Glutamyl transpeptidase activity in liver disease: serum elevation is independent of hepatic GGTP activity. | 1982 | Details |
| A47605 | 35202510 | Hepatol Commun | Development of a Robotic Shear Wave Elastography System for Noninvasive Staging of Liver Disease in Murine Models. | 2022 | Details |
| A47606 | 35195005 | J Med Chem | Phosphodiesters as GPR84 Antagonists for the Treatment of Ulcerative Colitis. | 2022 | Details |
| A47620 | 34963997 | Pain Rep | Management of post-cervical laminectomy fusion pain syndrome with a successful trial of spinal cord stimulation. | 2021 | Details |
| A47624 | 34816633 | Hepatol Commun | Pcsk9 Deletion Promotes Murine Nonalcoholic Steatohepatitis and Hepatic Carcinogenesis: Role of Cholesterol. | 2021 | Details |
| A47626 | 34796287 | JMA J | The Way to Decoding Pathogenesis and Conquering of National Afflictions, Viral Hepatitis and Liver Cancer. | 2021 | Details |
| A47631 | 34596311 | Hepatol Res | Artificial intelligence has come to hepatology. | 2021 | Details |
| A47634 | 34535788 | Nat Rev Drug Discov | Emerging therapeutic opportunities for integrin inhibitors. | 2021 | Details |
| A47635 | 34535664 | Nat Commun | A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discovery. | 2021 | Details |
| A47636 | 34532420 | Ann Transl Med | More promising results of liver intravoxel incoherent motion imaging analysis for the assessment of nonalcoholic steatohepatitis and fibrosis. | 2021 | Details |
| A47638 | 34531950 | ACS Med Chem Lett | Discovery of BMS-986318, a Potent Nonbile Acid FXR Agonist for the Treatment of Nonalcoholic Steatohepatitis. | 2021 | Details |
| A47661 | 34084451 | Hepat Oncol | Endotrophin, a pro-peptide of Type VI collagen, is a biomarker of survival in cirrhotic patients with hepatocellular carcinoma. | 2020 | Details |
| A47663 | 34035743 | Gastroenterol Hepatol (N Y) | Current Understanding of Risk for Nonalcoholic Steatohepatitis and Progressive Fibrosis. | 2020 | Details |
| A47677 | 33829335 | Surg Today | Predictive scoring system for advanced liver fibrosis in Japanese patients with severe obesity. | 2021 | Details |
| A47680 | 33772021 | Nat Commun | Author Correction: AdipoR1/AdipoR2 dual agonist recovers nonalcoholic steatohepatitis and related fibrosis via endoplasmic reticulum-mitochondria axis. | 2021 | Details |
| A47685 | 33708350 | World J Hepatol | Adult human liver slice cultures: Modelling of liver fibrosis and evaluation of new anti-fibrotic drugs. | 2021 | Details |
| A47686 | 33706616 | Expert Rev Gastroenterol Hepatol | The clinical impact of cirrhosis on the postoperative outcomes of patients undergoing bariatric surgery: propensity score-matched analysis of 2011-2017 US hospitals. | 2021 | Details |
| A47705 | 33297569 | Cells | Function of TREM1 and TREM2 in Liver-Related Diseases. | 2020 | Details |
| A47706 | 33293768 | J Clin Biochem Nutr | Trans-portal hepatic infusion of cultured bone marrow-derived mesenchymal stem cells in a steatohepatitis murine model. | 2020 | Details |
| A47709 | 33214232 | BMJ Open Gastroenterol | Association between behavioural risk factors for chronic liver disease and transient elastography measurements across the UK: a cross-sectional study. | 2020 | Details |
| A47711 | 33159158 | Cell Mol Immunol | Neutrophils in liver diseases: pathogenesis and therapeutic targets. | 2020 | Details |
| A47714 | 33129957 | Cancer Lett | Functional long non-coding RNAs in hepatocellular carcinoma. | 2020 | Details |
| A47722 | 32952970 | Mediterr J Hematol Infect Dis | Improvement of Liver Involvement in Familial Mediterranean Fever After the Introduction of Canakinumab: A Case Report. | 2020 | Details |
| A47723 | 32932781 | Int J Mol Sci | mRNA Post-Transcriptional Regulation by AU-Rich Element-Binding Proteins in Liver Inflammation and Cancer. | 2020 | Details |
| A47726 | 32892258 | Hepatol Int | Interleukin-22 in alcoholic hepatitis and beyond. | 2020 | Details |
| A47737 | 32705602 | Adv Exp Med Biol | CGI-58: Versatile Regulator of Intracellular Lipid Droplet Homeostasis. | 2020 | Details |
| A47744 | 32626839 | Hepatol Commun | The Hepatic Sinusoid in Aging and Disease: Update and Advances From the 20th Liver Sinusoid Meeting. | 2020 | Details |
| A47755 | 32439497 | Gastroenterology | Why do so many NASH trials fail? | 2020 | Details |
| A47759 | 32363321 | Hepatol Commun | Multispectral Imaging Enables Characterization of Intrahepatic Macrophages in Patients With Chronic Liver Disease. | 2020 | Details |
| A47765 | 32289375 | Gastroenterology | Hedgehog Signaling Demarcates a Niche of Fibrogenic Peribiliary Mesenchymal Cells. | 2020 | Details |
| A47776 | 34035715 | Gastroenterol Hepatol (N Y) | Role of Noninvasive Biomarkers in the Diagnosis of Nonalcoholic Steatohepatitis With Stage 2 or 3 Fibrosis. | 2020 | Details |
| A47789 | 31895219 | Invest Radiol | Molecular Magnetic Resonance Imaging of Fibrin Deposition in the Liver as an Indicator of Tissue Injury and Inflammation. | 2020 | Details |
| A47796 | 31735070 | Curr Eye Res | Diet Mimicking "Fast Food" Causes Structural Changes to the Retina Relevant to Age-Related Macular Degeneration. | 2019 | Details |
| A47801 | 31664017 | Nat Commun | Early detection and staging of chronic liver diseases with a protein MRI contrast agent. | 2019 | Details |
| A47810 | 31487518 | Int J Biol Macromol | Protective effects of polysaccharides on hepatic injury: A review. | 2019 | Details |
| A47812 | 31476281 | Transl Res | siRNA- and miRNA-based therapeutics for liver fibrosis. | 2019 | Details |
| A47815 | 31434650 | Diabetes Care | Acquired Generalized Lipodystrophy: A New Cause of Anti-PD-1 Immune-Related Diabetes. | 2019 | Details |
| A47820 | 31389060 | J Appl Toxicol | Free radicals, antioxidants, nuclear factor-E2-related factor-2 and liver damage. | 2019 | Details |
| A47823 | 31302759 | Handb Exp Pharmacol | Bile Acid-Activated Receptors: GPBAR1 (TGR5) and Other G Protein-Coupled Receptors. | 2019 | Details |
| A47827 | 31281379 | Stem Cells Int | Human Liver-Derived Stem Cells Improve Fibrosis and Inflammation Associated with Nonalcoholic Steatohepatitis. | 2019 | Details |
| A47830 | 31213776 | Drug Des Devel Ther | Salvianolic acid A attenuates CCl4-induced liver fibrosis by regulating the PI3K/AKT/mTOR, Bcl-2/Bax and caspase-3/cleaved caspase-3 signaling pathways. | 2019 | Details |
| A47835 | 31168508 | Hepatol Commun | Liver Macrophages: Old Dogmas and New Insights. | 2019 | Details |
| A47842 | 31081193 | Basic Clin Pharmacol Toxicol | Retraction. | 2019 | Details |
| A47846 | 31005555 | Dig Liver Dis | Myostatin regulates the fibrogenic phenotype of hepatic stellate cells via c-jun N-terminal kinase activation. | 2019 | Details |
| A47854 | 30836093 | Gastroenterology | HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response. | 2019 | Details |
| A47860 | 30720567 | J Thorac Imaging | Noncontrast Chest Computed Tomographic Imaging of Obesity and the Metabolic Syndrome: Part II Noncardiovascular Findings. | 2019 | Details |
| A47873 | 30393432 | J Toxicol Pathol | Hepatic lesions induced by feeding Western diets to Zucker fatty rats, an insulin-resistant model. | 2018 | Details |
| A47876 | 30308992 | Int J Mol Sci | Wnt/β-Catenin Signaling as a Potential Target for the Treatment of Liver Cirrhosis Using Antifibrotic Drugs. | 2018 | Details |
| A47878 | 30202816 | Hepatol Commun | High-Mobility Group Box-1 and Liver Disease. | 2018 | Details |
| A47886 | 30063802 | Hepatology | Emricasan (IDN-6556) Lowers Portal Pressure in Patients With Compensated Cirrhosis and Severe Portal Hypertension. | 2018 | Details |
| A47887 | 30019784 | Clin Exp Pharmacol Physiol | "Extracellular matrix remodelling in the liver of rats subjected to dietary choline deprivation and/or thioacetamide administration". | 2018 | Details |
| A47888 | 30008587 | Int J Med Sci | Hyperbaric Oxygen Therapy in Liver Diseases. | 2018 | Details |
| A47889 | 30004270 | J Laparoendosc Adv Surg Tech A | Preoperative Evaluation in Bariatric Surgery. | 2018 | Details |
| A47898 | 29773891 | Sci Rep | Assessing the Feasibility of Neutralizing Osteopontin with Various Therapeutic Antibody Modalities. | 2018 | Details |
| A47902 | 29656147 | Matrix Biol | Liver fibrosis: Direct antifibrotic agents and targeted therapies. | 2018 | Details |
| A47903 | 29619419 | Hepatol Commun | Tumor necrosis factor-α-mediated hepatocyte apoptosis stimulates fibrosis in the steatotic liver in mice. | 2018 | Details |
| A47909 | 29486473 | Cell Physiol Biochem | ShenFu Preparation Protects AML12 Cells Against Palmitic Acid-Induced Injury Through Inhibition of Both JNK/Nox4 and JNK/NFκB Pathways. | 2018 | Details |
| A47912 | 29427621 | Exp Cell Res | Brg1 promotes liver fibrosis via activation of hepatic stellate cells. | 2018 | Details |
| A47925 | 29158695 | Hepat Med | PNPLA3 expression and its impact on the liver: current perspectives. | 2017 | Details |
| A47941 | 28701893 | Yonago Acta Med | Risk Assessment of Hepatocellular Carcinoma in General Population by Liver Stiffness in Combination with Controlled Attenuation Parameter using Transient Elastography: A Cross Sectional Study. | 2017 | Details |
| A47946 | 28564720 | Semin Liver Dis | Inflammasomes in Liver Fibrosis. | 2017 | Details |
| A47950 | 28513320 | Cancer Biol Ther | CRISPR/Cas9-based Pten knock-out and Sleeping Beauty Transposon-mediated Nras knock-in induces hepatocellular carcinoma and hepatic lipid accumulation in mice. | 2017 | Details |
| A47951 | 28503559 | Hepatobiliary Surg Nutr | Cell-free DNA methylation as liquid biopsy for the assessment of fibrosis in patients with nonalcoholic steatohepatitis: a gap between innovation and implementation. | 2017 | Details |
| A47953 | 28480218 | Biomed Res Int | Magnetic Resonance Elastography Shear Wave Velocity Correlates with Liver Fibrosis and Hepatic Venous Pressure Gradient in Adults with Advanced Liver Disease. | 2017 | Details |
| A47960 | 28098353 | J Cell Physiol | The role of various peroxisome proliferator-activated receptors and their ligands in clinical practice. | 2017 | Details |
| A47972 | 27765759 | Am J Physiol Gastrointest Liver Physiol | Fibrogenesis assessed by serological type III collagen formation identifies patients with progressive liver fibrosis and responders to a potential antifibrotic therapy. | 2016 | Details |
| A47982 | 27425465 | J Steroid Biochem Mol Biol | Cardiopulmonary protective effects of the selective FXR agonist obeticholic acid in the rat model of monocrotaline-induced pulmonary hypertension. | 2016 | Details |
| A47984 | 29201761 | Euroasian J Hepatogastroenterol | Biochemical Scoring System for diagnosing Nonalcoholic Steatohepatitis. | 2016 | Details |
| A47987 | 27169903 | Clin Transl Sci | Pharmacokinetics, Safety, and CCR2/CCR5 Antagonist Activity of Cenicriviroc in Participants With Mild or Moderate Hepatic Impairment. | 2016 | Details |
| A47994 | 26965155 | Surg Obes Relat Dis | Use of noninvasive markers to predict advanced fibrosis/cirrhosis in severe obesity. | 2015 | Details |
| A48006 | 26781175 | Mol Med Rep | TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice. | 2016 | Details |
| A48012 | 26562527 | Biochem Biophys Res Commun | Effect of acid-sensing ion channel 1a on the process of liver fibrosis under hyperglycemia. | 2015 | Details |
| A48023 | 26305067 | Clin Gastroenterol Hepatol | A Variant in PNPLA3 Associated With Fibrosis Progression but not Hepatocellular Carcinoma in Patients With Hepatitis C Virus Infection. | 2015 | Details |
| A48030 | 26020068 | Drugs Today (Barc) | A report from the European Association for the Study of the Liver's 50th International Liver Congress (April 22-26 - Vienna, Austria). | 2015 | Details |
| A48042 | 25866507 | Gastroenterol Res Pract | Treatment of nonalcoholic steatohepatitis in adults: present and future. | 2015 | Details |
| A48043 | 25857940 | Acad Radiol | Efficacy and Accessibility of a Novel Liver Fibrosis Evaluation Program: Limited Abdominal Ultrasound with Concurrent Transient Elastography. | 2015 | Details |
| A48046 | 25763828 | Radiology | Combined Use of MR Fat Quantification and MR Elastography in Living Liver Donors: Can It Reduce the Need for Preoperative Liver Biopsy? | 2015 | Details |
| A48048 | 25715168 | J Interferon Cytokine Res | Interferon-β Mediates Signaling Pathways Uniquely Regulated in Hepatic Stellate Cells and Attenuates the Progression of Hepatic Fibrosis in a Dietary Mouse Model. | 2015 | Details |
| A48051 | 25596930 | Dig Liver Dis | Patients with chronic hepatitis C without advanced fibrosis and hepatocellular carcinoma: a retrospective clinical-pathological study. | 2014 | Details |
| A48056 | 25473202 | World J Gastroenterol | Red cell distribution width and nonalcoholic steatohepatitis. | 2014 | Details |
| A48065 | 27278026 | J Med Ultrason (2001) | Real-time tissue elastography (RTE) for noninvasive evaluation of fibrosis in liver diseases in children in comparison to liver biopsy. | 2014 | Details |
| A48071 | 25080449 | Gut | Gastric bypass surgery in NASH: a major modulator of hepatic mitochondrial dysfunction. | 2014 | Details |
| A48075 | 24901828 | Eur J Gastroenterol Hepatol | Is hematocrit really associated with fibrosis in patients with nonalcoholic steatohepatitis? | 2014 | Details |
| A48081 | 24633972 | Hepatology | Epigenetics in liver disease. | 2014 | Details |