Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Insulin9623 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A52546 | 25736229 | Obes Surg | Sleeve Gastrectomy Reduces Hepatic Steatosis by Improving the Coordinated Regulation of Aquaglyceroporins in Adipose Tissue and Liver in Obese Rats. | 2015 | Details |
| A52547 | 25723909 | Appl Physiol Nutr Metab | Carnitine supplementation alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats. | 2015 | Details |
| A52548 | 25723054 | Scand J Clin Lab Invest | Serum fetuin-A and arginase-1 in human obesity model: Is there any interaction between inflammatory status and arginine metabolism? | 2015 | Details |
| A52549 | 25695383 | Rev Invest Clin | Association of fatty liver with cardiovascular risk factors and subclinical atherosclerosis in a Mexican population. | 2015 | Details |
| A52552 | 25675425 | Pediatr Res | IUGR with infantile overnutrition programs an insulin-resistant phenotype through DNA methylation of peroxisome proliferator-activated receptor-γ coactivator-1α in rats. | 2015 | Details |
| A52553 | 25658017 | J Clin Endocrinol Metab | Subchronic sleep restriction causes tissue-specific insulin resistance. | 2015 | Details |
| A52554 | 25656826 | Trends Endocrinol Metab | Adipocytokines and hepatic fibrosis. | 2015 | Details |
| A52556 | 25638597 | Nutr Metab Cardiovasc Dis | Consumption of a whey protein-enriched diet may prevent hepatic steatosis associated with weight gain in elderly women. | 2014 | Details |
| A52558 | 25632931 | Semin Liver Dis | MicroRNAs in fatty liver disease. | 2015 | Details |
| A52559 | 25628422 | Am J Physiol Endocrinol Metab | Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity. | 2015 | Details |
| A52563 | 25592279 | Mol Biosyst | Dissection of metabolic pathways in the Db/Db mouse model by integrative proteome and acetylome analysis. | 2015 | Details |
| A52569 | 25497809 | J Dairy Sci | Body condition score at calving affects systemic and hepatic transcriptome indicators of inflammation and nutrient metabolism in grazing dairy cows. | 2014 | Details |
| A52570 | 25487878 | Sci Rep | Protopanaxatriol, a novel PPARγ antagonist from Panax ginseng, alleviates steatosis in mice. | 2014 | Details |
| A52575 | 25443347 | J Hepatol | Facts and fictions of HCV and comorbidities: steatosis, diabetes mellitus, and cardiovascular diseases. | 2014 | Details |
| A52577 | 25437555 | Cell Rep | Changes in nucleosome occupancy associated with metabolic alterations in aged mammalian liver. | 2014 | Details |
| A52583 | 25376159 | J Gastroenterol Hepatol | Hepatic fat, not visceral fat, is associated with gallbladder polyps: a study of 2643 healthy subjects. | 2015 | Details |
| A52584 | 25367448 | BMC Med | FTO rs9939609 polymorphism is associated with metabolic disturbances and response to HCV therapy in HIV/HCV-coinfected patients. | 2014 | Details |
| A52587 | 25329603 | Nutr Diabetes | Altered levels of serum sphingomyelin and ceramide containing distinct acyl chains in young obese adults. | 2014 | Details |
| A52588 | 25295789 | Cell Metab | CerS2 haploinsufficiency inhibits β-oxidation and confers susceptibility to diet-induced steatohepatitis and insulin resistance. | 2014 | Details |
| A52589 | 25294945 | Diabetes | Anti-CD44 antibody treatment lowers hyperglycemia and improves insulin resistance, adipose inflammation, and hepatic steatosis in diet-induced obese mice. | 2014 | Details |
| A52590 | 25294012 | Endocrine | Prediabetes and associated disorders. | 2014 | Details |
| A52594 | 25203718 | Hepatology | Effect of sofosbuvir and ribavirin treatment on peripheral and hepatic lipid metabolism in chronic hepatitis C virus, genotype 1-infected patients. | 2015 | Details |
| A52595 | 25190687 | Nutr Clin Pract | Nutrition status of patients with chronic hepatitis B or C. | 2014 | Details |
| A52600 | 25092429 | J Gastroenterol Hepatol | Hepatitis B virus infection and metabolic syndrome: fact or fiction? | 2015 | Details |
| A52602 | 25053728 | Eur J Endocrinol | Fatty liver largely explains associations of subclinical hypothyroidism with insulin resistance, metabolic syndrome, and subclinical coronary atherosclerosis. | 2014 | Details |
| A52603 | 25034291 | Dig Dis | Adipocyte cell death, fatty liver disease and associated metabolic disorders. | 2014 | Details |
| A52604 | 25017306 | Mol Immunol | The complement system in human cardiometabolic disease. | 2014 | Details |
| A52605 | 25013400 | J Biomed Res | Rab proteins implicated in lipid storage and mobilization. | 2014 | Details |
| A52607 | 24991042 | J Nutr | High-viscosity dietary fibers reduce adiposity and decrease hepatic steatosis in rats fed a high-fat diet. | 2014 | Details |
| A52611 | 24916550 | Nutr Res | Liver function parameters, cholesterol, and phospholipid α-linoleic acid are associated with adipokine levels in overweight and obese adults. | 2014 | Details |
| A52613 | 24889609 | Proc Natl Acad Sci U S A | 11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess. | 2014 | Details |
| A52615 | 24861288 | Rev Soc Bras Med Trop | Clinical and laboratory characteristics associated with dyslipidemia and liver steatosis in chronic HBV carriers. | 2014 | Details |
| A52616 | 24834723 | Ukr Biochem J | [The effect of N-stearoylethanolamine on liver phospholipid composition of rats with insulin resistance caused by alimentary obesity]. | 2014 | Details |
| A52617 | 24799023 | Horm Metab Res | Systemic metabolic signaling in acute and chronic gastrointestinal inflammation of inflammatory bowel diseases. | 2014 | Details |
| A52619 | 24756314 | Metab Brain Dis | Myeloid-specific deletion of SIRT1 increases hepatic steatosis and hypothalamic inflammation in mice fed a high-fat diet. | 2014 | Details |
| A52622 | 24679404 | Animal | Reproductive tract inflammatory disease in postpartum dairy cows. | 2014 | Details |
| A52623 | 24678942 | Ren Fail | The association between renal stone disease and cholesterol gallstones: the easy to believe and not hard to retrieve theory of the metabolic syndrome. | 2014 | Details |
| A52624 | 24659875 | World J Gastroenterol | Hepatitis C virus and metabolic disorder interactions towards liver damage and atherosclerosis. | 2014 | Details |
| A52627 | 24613289 | Mayo Clin Proc | Ethnic and sex differences in fatty liver on cardiac computed tomography: the multi-ethnic study of atherosclerosis. | 2014 | Details |
| A52631 | 24486395 | Eur J Pharmacol | Silymarin ameliorates fructose induced insulin resistance syndrome by reducing de novo hepatic lipogenesis in the rat. | 2014 | Details |
| A52634 | 24447068 | Metab Syndr Relat Disord | Metabolic syndrome in Turner syndrome and relation between body composition and clinical, genetic, and ultrasonographic characteristics. | 2014 | Details |
| A52635 | 24438728 | Prog Cardiovasc Dis | Overview of epidemiology and contribution of obesity to cardiovascular disease. | 2013 | Details |
| A52637 | 24400816 | BMC Public Health | Beyond BMI: The "Metabolically healthy obese" phenotype & its association with clinical/subclinical cardiovascular disease and all-cause mortality -- a systematic review. | 2014 | Details |
| A52638 | 24333420 | Biochem Biophys Res Commun | 8-Oxo-2'-deoxyguanosine ameliorates features of metabolic syndrome in obese mice. | 2013 | Details |
| A52641 | 24297848 | J Physiol | Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies. | 2013 | Details |
| A52642 | 24281976 | Curr Cardiol Rep | Impact of obesity and bariatric surgery on metabolism and coronary circulatory function. | 2014 | Details |
| A52643 | 24260478 | PLoS One | Deep sequencing of small RNA repertoires in mice reveals metabolic disorders-associated hepatic miRNAs. | 2013 | Details |
| A52649 | 24187406 | J Clin Endocrinol Metab | Toll-like receptor status in obesity and metabolic syndrome: a translational perspective. | 2013 | Details |
| A52651 | 24146946 | PLoS One | Effects of taurine supplementation on hepatic markers of inflammation and lipid metabolism in mothers and offspring in the setting of maternal obesity. | 2013 | Details |
| A52655 | 24101915 | Front Endocrinol (Lausanne) | Development and application of specific cytokine assays in tissue samples from a bottlenose dolphin with hyperinsulinemia. | 2013 | Details |
| A52659 | 24025398 | Circ J | Expanding role of delta-like 4 mediated notch signaling in cardiovascular and metabolic diseases. | 2013 | Details |
| A52660 | 24012029 | Am J Cardiol | Relation of hepatic steatosis to atherogenic dyslipidemia. | 2013 | Details |
| A52665 | 23954796 | J Am Heart Assoc | Hepatic extracellular signal-regulated kinase 2 suppresses endoplasmic reticulum stress and protects from oxidative stress and endothelial dysfunction. | 2013 | Details |
| A52666 | 23941362 | Nutr J | Effects of lifestyle changes including specific dietary intervention and physical activity in the management of patients with chronic hepatitis C--a randomized trial. | 2013 | Details |
| A52668 | 23886976 | Benef Microbes | Gut microbiota controls adipose tissue expansion, gut barrier and glucose metabolism: novel insights into molecular targets and interventions using prebiotics. | 2014 | Details |
| A52671 | 23824421 | J Clin Endocrinol Metab | Metabolic consequences of adipose triglyceride lipase deficiency in humans: an in vivo study in patients with neutral lipid storage disease with myopathy. | 2013 | Details |
| A52672 | 23809427 | Metabolism | Association of estrogen receptor alpha gene polymorphisms with metabolic syndrome in Egyptian women. | 2013 | Details |
| A52674 | 23769925 | Gene | The C57BL/6J Niemann-Pick C1 mouse model with decreased gene dosage has impaired glucose tolerance independent of body weight. | 2013 | Details |
| A52677 | 23697588 | Obes Res Clin Pract | Ethnic difference in liver fat content: a cross-sectional observation among Japanese American in Hawaii, Japanese in Japan, and non-Hispanic whites in United States. | 2013 | Details |
| A52678 | 23687413 | World J Gastroenterol | Lipoic acid suppresses portal endotoxemia-induced steatohepatitis and pancreatic inflammation in rats. | 2013 | Details |
| A52685 | 23551521 | J Intern Med | Ectopic lipid storage and insulin resistance: a harmful relationship. | 2013 | Details |
| A52686 | 23550081 | Endocr Rev | Adiposity and insulin resistance in humans: the role of the different tissue and cellular lipid depots. | 2013 | Details |
| A52689 | 23510830 | Atherosclerosis | Enhanced adiponectin actions by overexpression of adiponectin receptor 1 in macrophages. | 2013 | Details |
| A52690 | 23509418 | Mediators Inflamm | Lipotoxicity: effects of dietary saturated and transfatty acids. | 2013 | Details |
| A52693 | 23445230 | Expert Rev Gastroenterol Hepatol | The predictive value of steatosis in hepatitis C virus infection. | 2013 | Details |
| A52694 | 23431266 | PLoS Biol | Partial inhibition of adipose tissue lipolysis improves glucose metabolism and insulin sensitivity without alteration of fat mass. | 2013 | Details |
| A52696 | 23398239 | Alcohol Clin Exp Res | Temporal effects of ethanol consumption on energy homeostasis, hepatic steatosis, and insulin sensitivity in mice. | 2013 | Details |
| A52699 | 23341867 | PLoS One | Angiotensin AT(2) receptor contributes towards gender bias in weight gain. | 2013 | Details |
| A52701 | 23317789 | Prog Mol Biol Transl Sci | Adiponectin receptors in energy homeostasis and obesity pathogenesis. | 2013 | Details |
| A52702 | 23303913 | Physiol Rev | Pathophysiology of human visceral obesity: an update. | 2013 | Details |
| A52704 | 23250359 | Diabetes | Angiotensin 1-7 as means to prevent the metabolic syndrome: lessons from the fructose-fed rat model. | 2012 | Details |
| A52706 | 23226562 | PLoS One | Metabolic alterations and increased liver mTOR expression precede the development of autoimmune disease in a murine model of lupus erythematosus. | 2012 | Details |
| A52707 | 23176795 | Nutr Res | Genistein reduced insulin resistance index through modulating lipid metabolism in ovariectomized rats. | 2012 | Details |
| A52709 | 23128765 | Nestle Nutr Inst Workshop Ser | Targeting adipose tissue inflammation to treat the underlying basis of the metabolic complications of obesity. | 2012 | Details |
| A52712 | 23047931 | Endocr Pract | Development of type 2 diabetes mellitus in the obese adolescent: a growing challenge. | 2013 | Details |
| A52714 | 23043895 | Trends Endocrinol Metab | Dissociating fatty liver and diabetes. | 2012 | Details |
| A52717 | 22925001 | Br J Pharmacol | Small molecule glucokinase activators disturb lipid homeostasis and induce fatty liver in rodents: a warning for therapeutic applications in humans. | 2013 | Details |
| A52718 | 22895358 | Curr Opin Endocrinol Diabetes Obes | Are there still healthy obese patients? | 2012 | Details |
| A52722 | 22829562 | Endocr Rev | Cardiometabolic aspects of the polycystic ovary syndrome. | 2012 | Details |
| A52723 | 22825472 | Cell Death Dis | Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity. | 2012 | Details |
| A52724 | 22820893 | Endocrine | Fetuin-A and angiopoietins in obesity and type 2 diabetes mellitus. | 2012 | Details |
| A52725 | 22819899 | Hepatogastroenterology | Adiponectin and its receptors in chronic hepatitis B patients with metabolic syndrome in China. | 2012 | Details |
| A52727 | 22808905 | Endocr Regul | Aerobic training lasting for 10 weeks elevates the adipose tissue FABP4, Giα, and adiponectin expression associated by a reduced protein oxidation. | 2012 | Details |
| A52731 | 22701720 | PLoS One | Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids. | 2012 | Details |
| A52733 | 22670657 | Scand J Gastroenterol | Serum FGF21 and RBP4 levels in patients with chronic hepatitis C. | 2012 | Details |
| A52734 | 22664476 | J Clin Gastroenterol | Association of serum adipocytokines with insulin resistance and liver injury in patients with chronic hepatitis C genotype 4. | 2013 | Details |
| A52735 | 22662228 | PLoS One | Involvement of SIK3 in glucose and lipid homeostasis in mice. | 2012 | Details |
| A52741 | 22546774 | Int J Obes (Lond) | PNPLA3 gene-by-visceral adipose tissue volume interaction and the pathogenesis of fatty liver disease: the NHLBI family heart study. | 2012 | Details |
| A52742 | 22546076 | Atherosclerosis | Multiple factors and pathways involved in hepatic very low density lipoprotein-apoB100 overproduction in Otsuka Long-Evans Tokushima Fatty rats. | 2012 | Details |
| A52744 | 22506114 | Biochem Res Int | Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes. | 2012 | Details |
| A52745 | 22504062 | J Ethnopharmacol | Populus balsamifera L. (Salicaceae) mitigates the development of obesity and improves insulin sensitivity in a diet-induced obese mouse model. | 2012 | Details |
| A52746 | 22493234 | Proc Natl Acad Sci U S A | Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice. | 2012 | Details |
| A52749 | 22481453 | Ann Hepatol | Serum adipocyte fatty acid binding protein in liver transplant recipients and the metabolic syndrome. | 2012 | Details |
| A52750 | 22475652 | Diabetol Metab Syndr | High plasma uric acid concentration: causes and consequences. | 2012 | Details |
| A52751 | 22471957 | Cardiovasc Hematol Agents Med Chem | PPAR- γ agonist in treatment of diabetes: cardiovascular safety considerations. | 2012 | Details |
| A52753 | 22428554 | J Immunotoxicol | Effects of pioglitazone and/or simvastatin on circulating TNFα and adiponectin levels in insulin resistance. | 2012 | Details |
| A52756 | 22414273 | J Gastroenterol Hepatol | Cholesteryl ester transfer protein gene polymorphisms increase the risk of fatty liver in females independent of adiposity. | 2012 | Details |
| A52758 | 22393439 | PLoS One | Fatty liver index predicts further metabolic deteriorations in women with previous gestational diabetes. | 2012 | Details |
| A52759 | 22382323 | Biol Pharm Bull | Fenretinide ameliorates insulin resistance and fatty liver in obese mice. | 2012 | Details |
| A52760 | 22351884 | Pediatrics | Toward a unifying hypothesis of metabolic syndrome. | 2012 | Details |