Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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fibrosis10255 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A48570 | 33877727 | Hepatol Res | Validation of the FibroScan-aspartate aminotransferase score by vibration-controlled transient and B-mode ultrasound elastography. | 2021 | Details |
| A48575 | 33770118 | PLoS One | A two-hit model of alcoholic liver disease that exhibits rapid, severe fibrosis. | 2021 | Details |
| A48580 | 33679410 | Front Pharmacol | Inhibition of 5-Lipoxygenase in Hepatic Stellate Cells Alleviates Liver Fibrosis. | 2021 | Details |
| A48593 | 33433924 | J Pathol | Induced hepatic stellate cell integrin, α8β1, enhances cellular contractility and TGFβ activity in liver fibrosis. | 2021 | Details |
| A48598 | 33330821 | Glob Health Med | Hepatocyte ploidy and pathological mutations in hepatocellular carcinoma: impact on oncogenesis and therapeutics. | 2020 | Details |
| A48604 | 33208811 | Sci Rep | Elastic fibres in alcoholic liver disease. | 2020 | Details |
| A48611 | 33116742 | Clin Exp Gastroenterol | Erratum: Gut Dysbiosis and Increased Intestinal Permeability Drive microRNAs, NLRP-3 Inflammasome and Liver Fibrosis in a Nutritional Model of Non-Alcoholic Steatohepatitis in Adult Male Sprague Dawley Rats [Erratum]. | 2020 | Details |
| A48612 | 33113429 | Biomed Pharmacother | Plant-derived natural therapeutics targeting cannabinoid receptors in metabolic syndrome and its complications: A review. | 2020 | Details |
| A48613 | 33096030 | Clin Chim Acta | The apoM-S1P axis in hepatic diseases. | 2020 | Details |
| A48624 | 32764799 | PLoS One | Structurally distinct cyclosporin and sanglifehrin analogs CRV431 and NV556 suppress established HCV infection in humanized-liver mice. | 2020 | Details |
| A48627 | 32722345 | Cells | The Effects of PK11195 and Protoporphyrin IX Can Modulate Chronic Alcohol Intoxication in Rat Liver Mitochondria under the Opening of the Mitochondrial Permeability Transition Pore. | 2020 | Details |
| A48636 | 32640349 | Food Chem Toxicol | The liver fibrosis niche: Novel insights into the interplay between fibrosis-composing mesenchymal cells, immune cells, endothelial cells, and extracellular matrix. | 2020 | Details |
| A48638 | 32596881 | J Cell Mol Med | Salvianic acid A alleviates chronic alcoholic liver disease by inhibiting HMGB1 translocation via down-regulating BRD4. | 2020 | Details |
| A48641 | 32582143 | Front Immunol | The Genus Alistipes: Gut Bacteria With Emerging Implications to Inflammation, Cancer, and Mental Health. | 2020 | Details |
| A48644 | 32500081 | Front Mol Biosci | cis-4-[18F]fluoro-L-proline Molecular Imaging Experimental Liver Fibrosis. | 2020 | Details |
| A48645 | 32492766 | Clin Mol Hepatol | Role of cytoglobin, a novel radical scavenger, in stellate cell activation and hepatic fibrosis. | 2020 | Details |
| A48650 | 32371195 | J Hepatol | Danger signals in liver injury and restoration of homeostasis. | 2020 | Details |
| A48652 | 32329946 | Liver Int | A novel non-bile acid FXR agonist EDP-305 potently suppresses liver injury and fibrosis without worsening of ductular reaction. | 2020 | Details |
| A48653 | 32301252 | Liver Int | Longitudinal analysis of serum microRNAs as predictors of cirrhosis regression during treatment of hepatitis B virus infection. | 2020 | Details |
| A48655 | 32205992 | World J Gastroenterol | Role of spleen tyrosine kinase in liver diseases. | 2020 | Details |
| A48657 | 32139553 | Gut | Cirrhosis as new indication for statins. | 2020 | Details |
| A48658 | 32123215 | Sci Rep | Hepatic stellate cell hypertrophy is associated with metabolic liver fibrosis. | 2020 | Details |
| A48660 | 32064266 | Front Med (Lausanne) | Bile Acid Receptor Therapeutics Effects on Chronic Liver Diseases. | 2020 | Details |
| A48662 | 32039388 | JHEP Rep | Intrahepatic macrophage populations in the pathophysiology of primary sclerosing cholangitis. | 2019 | Details |
| A48666 | 31915600 | J Clin Transl Hepatol | Liver Stiffness Measurement Can Reflect the Active Liver Necroinflammation in Population with Chronic Liver Disease: A Real-world Evidence Study. | 2019 | Details |
| A48667 | 31915377 | Nature | TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1. | 2020 | Details |
| A48670 | 31849347 | J Hepatol | Autophagy in hepatic adaptation to stress. | 2020 | Details |
| A48674 | 31711802 | Toxicol Lett | PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury. | 2019 | Details |
| A48684 | 31548636 | Nat Rev Drug Discov | Targeting metabolic dysregulation for fibrosis therapy. | 2019 | Details |
| A48702 | 31128214 | Cancer Lett | Block of NF-kB signaling accelerates MYC-driven hepatocellular carcinogenesis and modifies the tumor phenotype towards combined hepatocellular cholangiocarcinoma. | 2019 | Details |
| A48703 | 31119644 | Drugs | Fibrosis in Chronic Liver Disease: An Update on Diagnostic and Treatment Modalities. | 2019 | Details |
| A48706 | 31069999 | J Hepatobiliary Pancreat Sci | Current status of hepatopulmonary syndrome in liver transplantation in Japan: a Japanese multicenter analysis. | 2019 | Details |
| A48714 | 30883752 | J Pathol | Bile ductular reactions in the liver: similarities are only skin deep. | 2019 | Details |
| A48727 | 30513996 | Int J Mol Sci | Genetic and Epigenetic Modifiers of Alcoholic Liver Disease. | 2018 | Details |
| A48731 | 30379089 | Mod Rheumatol | Validation of the fibrosis-4 (FIB-4) index in the diagnosis of liver disease of rheumatoid arthritis patients treated with methotrexate. | 2019 | Details |
| A48741 | 30165058 | Toxicol Appl Pharmacol | Nrf2 in alcoholic liver disease. | 2018 | Details |
| A48744 | 29966389 | Nutrients | Curcumin in Liver Diseases: A Systematic Review of the Cellular Mechanisms of Oxidative Stress and Clinical Perspective. | 2018 | Details |
| A48747 | 29915227 | Cell Death Dis | MicroRNA-214 promotes hepatic stellate cell activation and liver fibrosis by suppressing Sufu expression. | 2018 | Details |
| A48748 | 29892294 | Front Immunol | The Interleukin-20 Cytokine Family in Liver Disease. | 2018 | Details |
| A48754 | 29687200 | Probiotics Antimicrob Proteins | Are Probiotics Effective in Targeting Alcoholic Liver Diseases? | 2019 | Details |
| A48764 | 29379119 | Nat Immunol | The immunology of hepatocellular carcinoma. | 2018 | Details |
| A48765 | 29369503 | NMR Biomed | Magnetic resonance elastography of liver and spleen: Methods and applications. | 2018 | Details |
| A48766 | 29341392 | Liver Int | Cannabis use is associated with reduced prevalence of progressive stages of alcoholic liver disease. | 2018 | Details |
| A48780 | 28988570 | Alcohol Res | Alcoholic Liver Disease: Pathogenesis and Current Management. | 2017 | Details |
| A48782 | 28967501 | Ultrasound Med Biol | Intra-Individual Comparison between 2-D Shear Wave Elastography (GE System) and Virtual Touch Tissue Quantification (Siemens System) in Grading Liver Fibrosis. | 2017 | Details |
| A48790 | 28624101 | Best Pract Res Clin Gastroenterol | Reversal of liver fibrosis: From fiction to reality. | 2017 | Details |
| A48794 | 28474176 | Abdom Radiol (NY) | Hepatic venous pressure gradient correlates with advanced hepatic fibrosis: a retrospective review. | 2017 | Details |
| A48804 | 28050235 | World J Hepatol | Primary liver injury and delayed resolution of liver stiffness after alcohol detoxification in heavy drinkers with the PNPLA3 variant I148M. | 2016 | Details |
| A48813 | 27660175 | J Hepatol | The inflammasome in liver disease. | 2016 | Details |
| A48815 | 27728806 | Cancer Cell | p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer. | 2016 | Details |
| A48816 | 27714681 | Hepatol Int | Asian-Pacific Association for the Study of the Liver (APASL) consensus guidelines on invasive and non-invasive assessment of hepatic fibrosis: a 2016 update. | 2016 | Details |
| A48817 | 27709831 | J Cell Mol Med | GATA binding protein 3 is correlated with leptin regulation of PPARγ1 in hepatic stellate cells. | 2016 | Details |
| A48818 | 27701715 | Exp Clin Endocrinol Diabetes | Hypothyroidism Induces a Moderate Steatohepatitis Accompanied by Liver Regeneration, Mast Cells Infiltration, and Changes in the Expression of the Farnesoid X Receptor. | 2016 | Details |
| A48822 | 27574547 | World J Hepatol | Antifibrotic effects of ambrisentan, an endothelin-A receptor antagonist, in a non-alcoholic steatohepatitis mouse model. | 2016 | Details |
| A48823 | 27540438 | J Clin Med Res | Ultrasound Elastography Used for Preventive Non-Invasive Screening in Early Detection of Liver Fibrosis. | 2016 | Details |
| A48831 | 27158749 | Nat Rev Dis Primers | Hepatocellular carcinoma. | 2016 | Details |
| A48836 | 27003699 | Obes Surg | The Effect of Roux-en-Y vs. Omega-Loop Gastric Bypass on Liver, Metabolic Parameters, and Weight Loss. | 2016 | Details |
| A48839 | 26855815 | World J Gastrointest Pharmacol Ther | Clinical applications, limitations and future role of transient elastography in the management of liver disease. | 2016 | Details |
| A48841 | 26808690 | PLoS One | Hepatic Deficiency of Augmenter of Liver Regeneration Exacerbates Alcohol-Induced Liver Injury and Promotes Fibrosis in Mice. | 2016 | Details |
| A48845 | 26755860 | World J Gastroenterol | Metabolic derivatives of alcohol and the molecular culprits of fibro-hepatocarcinogenesis: Allies or enemies? | 2016 | Details |
| A48847 | 26738395 | Br J Biomed Sci | Pentraxin-3 and nitric oxide as indicators of disease severity in alcoholic cirrhosis. | 2015 | Details |
| A48849 | 26681055 | Genet Mol Res | Angiotensin-converting enzyme gene polymorphism (insertion/deletion) and liver fibrosis in Turkish patients from the western Black Sea region, Turkey. | 2015 | Details |
| A48851 | 26651978 | Curr Drug Metab | Indole-3-Carbinol (I3C) and its Major Derivatives: Their Pharmacokinetics and Important Roles in Hepatic Protection. | 2016 | Details |
| A48857 | 26448681 | Mediators Inflamm | C57BL/6 and A/J Mice Have Different Inflammatory Response and Liver Lipid Profile in Experimental Alcoholic Liver Disease. | 2015 | Details |
| A48859 | 26416085 | Hepatol Int | Will a second biopsy sample affect treatment decisions in patients with chronic hepatitis B? | 2015 | Details |
| A48866 | 26189980 | Clin Res Hepatol Gastroenterol | Liver fibrosis: Common mechanisms and antifibrotic therapies. | 2015 | Details |
| A48867 | 26097999 | Lab Invest | The role of iNOS in cholesterol-induced liver fibrosis. | 2015 | Details |
| A48869 | 26047667 | Arch Toxicol | Experimental models of liver fibrosis. | 2015 | Details |
| A48870 | 26019805 | Iran J Basic Med Sci | Modulation of IKKβ/NF-κB and TGF-β1/Smad via Fuzheng Huayu recipe involves in prevention of nutritional steatohepatitis and fibrosis in mice. | 2015 | Details |
| A48873 | 25941109 | Alcohol Clin Exp Res | Severe Vitamin D Deficiency May be an Additional Cofactor for the Occurrence of Alcoholic Steatohepatitis. | 2015 | Details |
| A48880 | 25800177 | Pancreatology | Metabolic reprogramming and cell fate regulation in alcoholic liver disease. | 2015 | Details |
| A48885 | 25603848 | Korean J Gastroenterol | [Diagnostic and therapeutic strategies for severe alcoholic hepatitis]. | 2015 | Details |
| A48887 | 25540733 | World J Transplant | Female gender in the setting of liver transplantation. | 2014 | Details |
| A48888 | 25531568 | Lab Invest | TRAIL-producing NK cells contribute to liver injury and related fibrogenesis in the context of GNMT deficiency. | 2014 | Details |
| A48893 | 25401051 | Curr Pathobiol Rep | Strategies to Detect Hepatic Myofibroblasts in Liver Cirrhosis of Different Etiologies. | 2014 | Details |
| A48895 | 25356026 | World J Gastroenterol | Non-invasive diagnosis of alcoholic liver disease. | 2014 | Details |
| A48901 | 25103596 | Acta Clin Belg | The value of liver and spleen ADC measurements in the diagnosis and follow up of hepatic fibrosis in chronic liver disease. | 2014 | Details |
| A48905 | 24896361 | Front Biosci (Landmark Ed) | MicroRNA in hepatic fibrosis and cirrhosis. | 2014 | Details |
| A48911 | 24796378 | Hepatol Res | Inhibition of acidic sphingomyelinase reduces established hepatic fibrosis in mice. | 2014 | Details |
| A48915 | 24622872 | Z Gastroenterol | [Cytokeratin 18 as marker for non-invasive diagnosis and prognosis of acute and chronic liver diseases]. | 2014 | Details |
| A48916 | 24592262 | Front Immunol | TWEAK and LTβ Signaling during Chronic Liver Disease. | 2014 | Details |
| A48917 | 24580680 | Hepatol Res | Third-generation inhibitor for the renin-angiotensin system: Can it strongly protect against progression of hepatic fibrosis in non-alcoholic steatohepatitis? | 2013 | Details |
| A48918 | 24498546 | Oncoimmunology | Role of lymphocytes in liver cancer. | 2013 | Details |
| A48919 | 24489787 | PLoS One | Model steatogenic compounds (amiodarone, valproic acid, and tetracycline) alter lipid metabolism by different mechanisms in mouse liver slices. | 2014 | Details |
| A48920 | 24438608 | Chin Med J (Engl) | Fasudil hydrochloride hydrate, a Rho-kinase inhibitor, ameliorates hepatic fibrosis in rats with type 2 diabetes. | 2014 | Details |
| A48921 | 24400890 | J Cell Mol Med | The functional role of microRNAs in alcoholic liver injury. | 2014 | Details |
| A48924 | 24379606 | World J Gastroenterol | Hierarchical and selective roles of galectins in hepatocarcinogenesis, liver fibrosis and inflammation of hepatocellular carcinoma. | 2013 | Details |
| A48927 | 24224451 | Pol Merkur Lekarski | [The diagnostic value of non-invasive biochemical biomarkers in alcohol abuse]. | 2013 | Details |
| A48934 | 24032513 | Mini Rev Med Chem | Triglyceride Metabolism and Hepatic Diseases. | 2013 | Details |
| A48935 | 23937266 | Hepatol Res | Pathological characteristics of patients who develop hepatocellular carcinoma with negative results of both serous hepatitis B surface antigen and hepatitis C virus antibody. | 2013 | Details |
| A48943 | 23663886 | Zhonghua Gan Zang Bing Za Zhi | [Activation of Fas/FasL and its downstream signaling pathway promotes development of alcoholic steatohepatitis and liver fibrosis in mice]. | 2013 | Details |
| A48944 | 23646229 | World J Hepatol | Lymphocyte subsets in alcoholic liver disease. | 2013 | Details |
| A48951 | 23388073 | Lipids Health Dis | Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol mediated liver fibrosis in mice. | 2013 | Details |
| A48954 | 23301878 | Hepatol Res | Chymase inhibitor ameliorates hepatic steatosis and fibrosis on established non-alcoholic steatohepatitis in hamsters fed a methionine- and choline-deficient diet. | 2013 | Details |
| A48960 | 23161303 | Turk J Gastroenterol | Alpha-1 antitrypsin deficiency in patients with chronic hepatitis. | 2012 | Details |
| A48963 | 23057725 | Hepatol Res | Fatty liver Shionogi-ob/ob mouse: A new candidate for a non-alcoholic steatohepatitis model. | 2012 | Details |
| A48966 | 22959770 | Biochem Biophys Res Commun | Expression and function of the atypical cadherin FAT1 in chronic liver disease. | 2012 | Details |
| A48973 | 22661952 | Front Physiol | Toll-like receptors in liver fibrosis: cellular crosstalk and mechanisms. | 2012 | Details |
| A48977 | 22489261 | World J Hepatol | Human immunodeficiency virus infection and the liver. | 2012 | Details |
| A48978 | 22452372 | Br J Pharmacol | Curcumin ameliorates hepatic fibrosis in type 2 diabetes mellitus - insights into its mechanisms of action. | 2012 | Details |