Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Article ID | PMID | Source | Title | Publish Year | |
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A49712 | 35661987 | Hormones (Athens) | Non-invasive diagnosis and staging of non-alcoholic fatty liver disease. | 2022 | Details |
A49714 | 35661191 | Aliment Pharmacol Ther | Review article: vascular effects of PPARs in the context of NASH. | 2022 | Details |
A49718 | 35659603 | Clin Res Hepatol Gastroenterol | Effect of novel glucose lowering agents on non-alcoholic fatty liver disease: A systematic review and meta-analysis. | 2022 | Details |
A49723 | 35657576 | Clin Rev Allergy Immunol | Serum Biomarkers for Autoimmune Hepatitis Type 1: the Case for CD48 and a Review of the Literature. | 2022 | Details |
A49724 | 35657189 | Rev Med Liege | [Non-alcoholic steatohepatitis (NASH) : a model of metabolic inflammation («metaflammation»)]. | 2022 | Details |
A49725 | 35657127 | Arch Endocrinol Metab | Risk factors associated with nonalcoholic fatty liver disease evaluated by elastography in patients with type 2 diabetes. | 2022 | Details |
A49726 | 35657121 | J Viral Hepat | Posttreatment nonalcoholic fatty liver disease fibrosis scores for predicting liver-related complications in patients with chronic hepatitis C receiving direct-acting antiviral agents. | 2022 | Details |
A49731 | 35655171 | BMC Gastroenterol | Two differentially methylated region networks in nonalcoholic fatty liver disease, viral hepatitis, and hepatocellular carcinoma. | 2022 | Details |
A49736 | 35654350 | J Ethnopharmacol | Danhe granule ameliorates nonalcoholic steatohepatitis and fibrosis in rats by inhibiting ceramide de novo synthesis related to CerS6 and CerK. | 2022 | Details |
A49737 | 35654298 | Clin Gastroenterol Hepatol | Poor Diagnostic Efficacy of Noninvasive Tests for Advanced Fibrosis in Obese or Younger Than 60 Diabetic NAFLD patients. | 2022 | Details |
A49744 | 35651885 | Metabol Open | Effect of 8 Weeks milk thistle powder (silymarin extract) supplementation on fatty liver disease in patients candidates for bariatric surgery. | 2022 | Details |
A49752 | 35647690 | Microbiol Spectr | Longitudinal 16S rRNA Sequencing Reveals Relationships among Alterations of Gut Microbiota and Nonalcoholic Fatty Liver Disease Progression in Mice. | 2022 | Details |
A49753 | 35647047 | Front Cardiovasc Med | Association Between Metabolic Dysfunction-Associated Fatty Liver Disease and Cardiovascular Risk in Patients With Rheumatoid Arthritis: A Cross-Sectional Study of Chinese Cohort. | 2022 | Details |
A49755 | 35646285 | World J Gastrointest Oncol | Gut microbiome in non-alcoholic fatty liver disease associated hepatocellular carcinoma: Current knowledge and potential for therapeutics. | 2022 | Details |
A49757 | 35646268 | World J Hepatol | Correlation between Fibroscan and laboratory tests in non-alcoholic fatty liver disease/non-alcoholic steatohepatitis patients for assessing liver fibrosis. | 2022 | Details |
A49760 | 35645140 | Saudi J Gastroenterol | Transient elastography for the prevalence of non-alcoholic fatty liver disease in patients with type 2 diabetes: Evidence from the CORDIAL cohort study. | 2022 | Details |
A49764 | 35643936 | Liver Int | Prevalence estimation of significant fibrosis because of NASH in Spain combining transient elastography and histology. | 2022 | Details |
A49767 | 35643859 | Lab Invest | A diet-induced murine model for non-alcoholic fatty liver disease with obesity and insulin resistance that rapidly develops steatohepatitis and fibrosis. | 2022 | Details |
A49770 | 35643287 | J Nutr Biochem | Opisthorchis viverrini infection induces metabolic disturbances in hamsters fed with high fat/high fructose diets: Implications for liver and kidney pathologies. | 2022 | Details |
A49776 | 35641932 | BMC Endocr Disord | Correlation between the thyroid hormone levels and nonalcoholic fatty liver disease in type 2 diabetic patients with normal thyroid function. | 2022 | Details |
A49780 | 35639554 | J Gastroenterol Hepatol | GGT dynamic for advanced fibrosis in NAFLD: Novel but not convincing. | 2022 | Details |
A49784 | 35639028 | FASEB J | A new preclinical model of western diet-induced progression of non-alcoholic steatohepatitis to hepatocellular carcinoma. | 2022 | Details |
A49793 | 35636146 | Neoplasia | Hepatocellular carcinoma in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis: HCC and Steatosis or Steatohepatitis. | 2022 | Details |
A49794 | 35635899 | Nutr Res | Higher hepatic advanced glycation end products and liver damage markers are associated with nonalcoholic steatohepatitis. | 2022 | Details |
A49795 | 35635761 | Liver Int | Comparison of point-shear wave elastography (ElastPQ) and transient elastography (FibroScan) for liver fibrosis staging in patients with non-alcoholic fatty liver disease. | 2022 | Details |
A49797 | 35635048 | Ann Med | Role of silymarin as antioxidant in clinical management of chronic liver diseases: a narrative review. | 2022 | Details |
A49799 | 35634402 | Front Nutr | Liver Protein Expression in NASH Mice on a High-Fat Diet: Response to Multi-Mineral Intervention. | 2022 | Details |
A49800 | 35634340 | Front Immunol | The Potential Role of Gut Microbial-Derived Exosomes in Metabolic-Associated Fatty Liver Disease: Implications for Treatment. | 2022 | Details |
A49808 | 35630668 | Molecules | Non-Alcoholic Fatty Liver Disease in Long-Term Type 2 Diabetes: Role of rs738409 PNPLA3 and rs499765 FGF21 Polymorphisms and Serum Biomarkers. | 2022 | Details |
A49810 | 35630058 | Medicina (Kaunas) | Chronic Inflammation-A Link between Nonalcoholic Fatty Liver Disease (NAFLD) and Dysfunctional Adipose Tissue. | 2022 | Details |
A49818 | 35628889 | J Clin Med | Non-Alcoholic Fatty Liver Disease and Metabolic Syndrome in Women: Effects of Lifestyle Modifications. | 2022 | Details |
A49822 | 35628360 | Int J Mol Sci | Down-Regulating the High Level of 17-Beta-Hydroxysteroid Dehydrogenase 13 Plays a Therapeutic Role for Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
A49825 | 35626354 | Diagnostics (Basel) | Characteristics of Urine Organic Acid Metabolites in Nonalcoholic Fatty Liver Disease Assessed Using Magnetic Resonance Imaging with Elastography in Korean Adults. | 2022 | Details |
A49827 | 35625927 | Biomedicines | A Nine-Strain Bacterial Consortium Improves Portal Hypertension and Insulin Signaling and Delays NAFLD Progression In Vivo. | 2022 | Details |
A49831 | 35625660 | Biomolecules | Relationship between Liver Stiffness and Steatosis in Obesity Conditions: In Vivo and In Vitro Studies. | 2022 | Details |
A49832 | 35625625 | Biomolecules | Extracellular Vesicles from Steatotic Hepatocytes Provoke Pro-Fibrotic Responses in Cultured Stellate Cells. | 2022 | Details |
A49835 | 35625413 | Biology (Basel) | Comparison of the Modified TyG Indices and Other Parameters to Predict Non-Alcoholic Fatty Liver Disease in Youth. | 2022 | Details |
A49837 | 35624786 | Antioxidants (Basel) | The Role and Mechanisms of Selenium Supplementation on Fatty Liver-Associated Disorder. | 2022 | Details |
A49841 | 35624731 | Antioxidants (Basel) | Administration of Glutaredoxin-1 Attenuates Liver Fibrosis Caused by Aging and Non-Alcoholic Steatohepatitis. | 2022 | Details |
A49847 | 35622622 | Toxics | Bisphenol A Coupled with a High-Fat Diet Promotes Hepatosteatosis through Reactive-Oxygen-Species-Induced CD36 Overexpression. | 2022 | Details |
A49852 | 35618435 | Neurology | Association of Nonalcoholic Fatty Liver Disease and Fibrosis With Incident Dementia and Cognition: The Rotterdam Study. | 2022 | Details |
A49857 | 35617294 | PLoS One | Systematic screening for advanced liver fibrosis in patients with coronary artery disease: The CORONASH study. | 2022 | Details |
A49859 | 35616321 | Clin Transl Gastroenterol | Association of serum and fecal bile acid patterns with liver fibrosis in biopsy-proven nonalcoholic fatty liver disease: An observational study. | 2022 | Details |
A49863 | 35615095 | Front Med (Lausanne) | Endoscopic Bariatric and Metabolic Therapies and Their Effects on Metabolic Syndrome and Non-alcoholic Fatty Liver Disease - A Systematic Review and Meta-Analysis. | 2022 | Details |
A49864 | 35614939 | Front Pharmacol | Obeticholic Acid Induces Hepatoxicity Via FXR in the NAFLD Mice. | 2022 | Details |
A49865 | 35614896 | Visc Med | Diagnostic and Therapy of Nonalcoholic Fatty Liver Disease: A Narrative Review. | 2021 | Details |
A49871 | 35613944 | J Gastroenterol Hepatol | Patients with type 2 diabetes and elevated fibrosis-4 are under-referred to hepatology and have unrecognized hepatic decompensation. | 2022 | Details |
A49878 | 35611380 | Pediatr Gastroenterol Hepatol Nutr | Correlation between Transient Elastography (Fibroscan®) and Ultrasonographic and Computed Tomographic Grading in Pediatric Nonalcoholic Steatohepatitis. | 2022 | Details |
A49879 | 35611223 | JMA J | Positive Pattern Recognition System Using Alanine Aminotransferase, Type IV Collagen 7s, and E Value (Liver Stiffness) for the Diagnosis of Nonalcoholic Steatohepatitis Based on Natural History. | 2022 | Details |
A49881 | 35610402 | Pharm Res | Applications of Quantitative Systems Pharmacology (QSP) in Drug Development for NAFLD and NASH and Its Regulatory Application. | 2022 | Details |
A49882 | 35609858 | J Nutr Biochem | Phloretin mitigates oxidative injury, inflammation, and fibrogenic responses via restoration of autophagic flux in in vitro and preclinical models of NAFLD. | 2022 | Details |
A49883 | 35609854 | J Nutr Biochem | Excess fructose enhances oleatic cytotoxicity via reactive oxygen species production and causes necroptosis in hepatocytes. | 2022 | Details |
A49884 | 35609372 | Biomed Pharmacother | Roles of Yes-associated protein and transcriptional coactivator with PDZ-binding motif in non-neoplastic liver diseases. | 2022 | Details |
A49886 | 35608296 | Clin Transl Gastroenterol | The ability of lipoprotein (a) level to predict early carotid atherosclerosis is impaired in patients with advanced liver fibrosis related to metabolic associated fatty liver disease. | 2022 | Details |
A49890 | 35605893 | Clin Res Hepatol Gastroenterol | The prevalence of nonalcoholic fatty liver disease in Chinese adults screened by vibration controlled transient elastography and its diagnostic discrepancy compared with ultrasound. | 2022 | Details |
A49900 | 35603860 | Nutr Health | Decreased Serum zinc, selenium, and vitamin E as possible risk factors of hepatic fibrosis in non-alcoholic fatty liver disease. | 2022 | Details |
A49901 | 35603482 | Hepatology | PAR2 promotes impaired glucose uptake and insulin resistance in NAFLD through GLUT2 and Akt interference. | 2022 | Details |
A49903 | 35603224 | Front Immunol | Association of Inflammatory Cytokines With Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
A49904 | 35603209 | Front Immunol | Liver Stiffness by Transient Elastography Correlates With Degree of Portal Hypertension in Common Variable Immunodeficiency Patients With Nodular Regenerative Hyperplasia. | 2022 | Details |
A49905 | 35602098 | Oxid Med Cell Longev | A Molecular Insight into the Role of Antioxidants in Nonalcoholic Fatty Liver Diseases. | 2022 | Details |
A49907 | 35600209 | Can J Gastroenterol Hepatol | Glucocorticosteroids and the Risk of NAFLD in Inflammatory Bowel Disease. | 2022 | Details |
A49908 | 35599934 | Ann Gastroenterol | Frailty in metabolic syndrome, focusing on nonalcoholic fatty liver disease. | 2022 | Details |
A49910 | 35599922 | Ann Gastroenterol | Emerging advances in the pharmacologic treatment of nonalcoholic steatohepatitis and related cirrhosis. | 2022 | Details |
A49911 | 35599680 | Paediatr Child Health | Awareness, management, and practice patterns of pediatric NAFLD by primary care physicians. | 2021 | Details |
A49914 | 35598367 | Biomed Pharmacother | Natural PPARs agonists for the treatment of nonalcoholic fatty liver disease. | 2022 | Details |
A49915 | 35598211 | Orv Hetil | A nem alkoholos zsírmájbetegség és a 2-es típusú cukorbetegség. | 2022 | Details |
A49927 | 35592121 | Front Surg | Changes in Indices of Steatosis and Fibrosis in Liver Grafts of Living Donors After Weight Reduction. | 2022 | Details |
A49934 | 35589256 | J Hepatol | Impact of non-invasive biomarkers on hepatology practice: Past, present and future. | 2022 | Details |
A49935 | 35589249 | J Hepatol | Breakthroughs in therapies for NASH and remaining challenges. | 2022 | Details |
A49938 | 35588334 | Cell Mol Life Sci | Macrophages evoke autophagy of hepatic stellate cells to promote liver fibrosis in NAFLD mice via the PGE2/EP4 pathway. | 2022 | Details |
A49939 | 35588190 | Hepatology | Nonalcoholic fatty liver disease and accelerated loss of skeletal muscle mass: A longitudinal cohort study. | 2022 | Details |
A49940 | 35587726 | J Gastroenterol Hepatol | Validation of magnetic resonance elastography plus fibrosis-4 for significant fibrosis in nonalcoholic fatty liver disease. | 2022 | Details |
A49942 | 35586979 | Hepatology | Hepatocellular cystathionine γ lyase/hydrogen sulfide attenuates nonalcoholic fatty liver disease by activating farnesoid X receptor. | 2022 | Details |
A49943 | 35586202 | Diabetes Metab Syndr Obes | The Perirenal Fat Thickness Was Associated with Nonalcoholic Fatty Liver Disease in Patients with Type 2 Diabetes Mellitus. | 2022 | Details |
A49944 | 35586049 | Front Pharmacol | Artemether Ameliorates Non-Alcoholic Steatohepatitis by Repressing Lipogenesis, Inflammation, and Fibrosis in Mice. | 2022 | Details |
A49948 | 35585153 | Sci Rep | Incremental levels of diagnostic information incentivize health-seeking in non-alcoholic fatty liver: a randomized clinical trial. | 2022 | Details |
A49949 | 35584952 | Magn Reson Med Sci | Clinical Application of Quantitative MR Imaging in Nonalcoholic Fatty Liver Disease. | 2022 | Details |
A49950 | 35584814 | Annu Rev Nutr | Reprogramming of Hepatic Metabolism and Microenvironment in Nonalcoholic Steatohepatitis. | 2022 | Details |
A49955 | 35583480 | J Agric Food Chem | Spermidine Ameliorates Nonalcoholic Steatohepatitis through Thyroid Hormone-Responsive Protein Signaling and the Gut Microbiota-Mediated Metabolism of Bile Acids. | 2022 | Details |
A49956 | 35583419 | Minerva Med | Non-invasive biochemical markers and surrogate scores in evaluating non-alcoholic steatohepatitis. A narrative review. | 2022 | Details |
A49961 | 35582126 | World J Gastroenterol | Validation model of fibrosis-8 index score to predict significant fibrosis among patients with nonalcoholic fatty liver disease. | 2022 | Details |
A49962 | 35581956 | Hepatol Commun | Favorable impact of long-term SGLT2 inhibitor for NAFLD complicated by diabetes mellitus: A 5-year follow-up study. | 2022 | Details |
A49967 | 35579278 | Mol Syst Biol | Dynamic human liver proteome atlas reveals functional insights into disease pathways. | 2022 | Details |
A49968 | 35578969 | Compr Physiol | Oxidative Stress and Redox Signaling in the Pathophysiology of Liver Diseases. | 2022 | Details |
A49971 | 35578028 | Inflamm Res | Prolonged effects of DPP-4 inhibitors on steato-hepatitic changes in Sprague-Dawley rats fed a high-cholesterol diet. | 2022 | Details |
A49973 | 35577161 | J Ethnopharmacol | Network pharmacology analysis on mechanism of Jian Pi Qing Gan Yin decoction ameliorating high fat diet-induced non-alcoholic fatty liver disease and validated in vivo. | 2022 | Details |
A49976 | 35576742 | Phytomedicine | Multiple anti-non-alcoholic steatohepatitis (NASH) efficacies of isopropylidenyl anemosapogenin via farnesoid X receptor activation and TFEB-mediated autophagy. | 2022 | Details |
A49978 | 35574998 | Liver Int | Attribution of diabetes to the development of severe liver disease in the general population. | 2022 | Details |
A49982 | 35573018 | Front Med (Lausanne) | Editorial: Liver Fibrosis and MAFLD: From Molecular Aspects to Novel Pharmacological Strategies. | 2022 | Details |
A49990 | 35569823 | Korean J Intern Med | Changes in the prevalence of hepatitis B and metabolic abnormalities among young men in Korea. | 2022 | Details |
A49995 | 35568114 | J Ethnopharmacol | Ethanol extract of Pharbitis nil ameliorates liver fibrosis through regulation of the TGFβ1-SMAD2/3 pathway. | 2022 | Details |
A49996 | 35568098 | J Nutr Biochem | Indole supplementation ameliorates MCD-induced NASH in mice. | 2022 | Details |
A49998 | 35567505 | FASEB J | Mesencephalic astrocyte-derived neurotrophic factor alleviates non-alcoholic steatohepatitis induced by Western diet in mice. | 2022 | Details |
A50000 | 35566749 | J Clin Med | Hepatic Steatosis and Fibrosis in Chronic Inflammatory Bowel Disease. | 2022 | Details |
A50001 | 35566592 | J Clin Med | Non-Invasive Tests of Liver Fibrosis Help in Predicting the Development of Hepatocellular Carcinoma among Patients with NAFLD. | 2022 | Details |
A50002 | 35566571 | J Clin Med | Clinical Differences and Non-Alcoholic Fatty Liver Disease-Related Factors of Lean and Non-Lean Patients with Metabolic Syndrome. | 2022 | Details |
A50013 | 35563534 | Int J Mol Sci | Lipotoxicity as the Leading Cause of Non-Alcoholic Steatohepatitis. | 2022 | Details |
A50014 | 35563425 | Int J Mol Sci | Plasma Aldo-Keto Reductase Family 1 Member B10 as a Biomarker Performs Well in the Diagnosis of Nonalcoholic Steatohepatitis and Fibrosis. | 2022 | Details |
A50016 | 35563210 | Int J Mol Sci | Liver Steatosis: A Marker of Metabolic Risk in Children. | 2022 | Details |
A50019 | 35562689 | BMC Endocr Disord | Association between type 2 diabetes status and prevalence of liver steatosis and fibrosis among adults aged ≥ 40 years. | 2022 | Details |