Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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L-Carnitine64 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00980 | 34911556 | BMC Biol | Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress. | 2021 | Details |
| A01139 | 34857248 | Clin Nutr ESPEN | Effect of l-carnitine supplementation on liver fat content and cardiometabolic indices in overweight/obese women with polycystic ovary syndrome: A randomized controlled trial. | 2021 | Details |
| A01587 | 34684533 | Nutrients | Supplementation with a Specific Combination of Metabolic Cofactors Ameliorates Non-Alcoholic Fatty Liver Disease, Hepatic Fibrosis, and Insulin Resistance in Mice. | 2021 | Details |
| A01608 | 34680557 | Biomedicines | Combined Metabolic Activators Decrease Liver Steatosis by Activating Mitochondrial Metabolism in Hamsters Fed with a High-Fat Diet. | 2021 | Details |
| A02290 | 34434943 | Front Med (Lausanne) | Role of Carnitine in Non-alcoholic Fatty Liver Disease and Other Related Diseases: An Update. | 2021 | Details |
| A02474 | 34360538 | Int J Mol Sci | Diabetes Mellitus and Cardiovascular Diseases: Nutraceutical Interventions Related to Caloric Restriction. | 2021 | Details |
| A03391 | 34019353 | Vopr Pitan | [Specialized products for dietary correction of the diet of patients with non-alcoholic steatohepatitis]. | 2021 | Details |
| A03589 | 33939897 | J Pediatr Endocrinol Metab | Effect of l-carnitine supplementation on children and adolescents with nonalcoholic fatty liver disease (NAFLD): a randomized, triple-blind, placebo-controlled clinical trial. | 2021 | Details |
| A04721 | 33529448 | Liver Int | Maternal high-fat diet disrupted one-carbon metabolism in offspring, contributing to nonalcoholic fatty liver disease. | 2021 | Details |
| A04829 | 33491528 | J Diet Suppl | The Effects of Vitamin E, Silymarin and Carnitine on the Metabolic Abnormalities Associated with Nonalcoholic Liver Disease. | 2021 | Details |
| A05068 | 33388736 | Orv Hetil | Sarcopenia - 2021: Pathophysiology, diagnosis, therapy | 2021 | Details |
| A06273 | 32945305 | Food Funct | Lactobacillus fermentum CQPC06 in naturally fermented pickles prevents non-alcoholic fatty liver disease by stabilizing the gut-liver axis in mice. | 2020 | Details |
| A06472 | 32866186 | PLoS One | Differences among patients with and without nonalcoholic fatty liver disease having elevated alanine aminotransferase levels at various stages of metabolic syndrome. | 2020 | Details |
| A06890 | 32708036 | Nutrients | The Importance of the Fatty Acid Transporter L-Carnitine in Non-Alcoholic Fatty Liver Disease (NAFLD). | 2020 | Details |
| A06984 | 32673798 | Mol Metab | Non-alcoholic fatty liver disease and steatohepatitis: State of the art on effective therapeutics based on the gold standard method for diagnosis. | 2020 | Details |
| A07840 | 32337855 | Mol Syst Biol | The acute effect of metabolic cofactor supplementation: a potential therapeutic strategy against non-alcoholic fatty liver disease. | 2020 | Details |
| A08426 | 32115853 | Diabetes Obes Metab | A metabolomics-based molecular pathway analysis of how the sodium-glucose co-transporter-2 inhibitor dapagliflozin may slow kidney function decline in patients with diabetes. | 2020 | Details |
| A08451 | 32105727 | Gastroenterology | TMAVA, a Metabolite of Intestinal Microbes, Is Increased in Plasma From Patients With Liver Steatosis, Inhibits γ-Butyrobetaine Hydroxylase, and Exacerbates Fatty Liver in Mice. | 2020 | Details |
| A09536 | 31705397 | J Endocrinol Invest | L-Carnitine counteracts in vitro fructose-induced hepatic steatosis through targeting oxidative stress markers. | 2019 | Details |
| A09796 | 31607566 | Dig Liver Dis | L-carnitine supplementation attenuates NAFLD progression and cardiac dysfunction in a mouse model fed with methionine and choline-deficient diet. | 2019 | Details |
| A10090 | 31491949 | Int J Mol Sci | Combined Treatment with L-Carnitine and Nicotinamide Riboside Improves Hepatic Metabolism and Attenuates Obesity and Liver Steatosis. | 2019 | Details |
| A10262 | 31408176 | J Clin Endocrinol Metab | Hepatic Fatty Acid Balance and Hepatic Fat Content in Humans With Severe Obesity. | 2019 | Details |
| A10435 | 31336926 | Nutrients | The Potential Use of Metabolic Cofactors in Treatment of NAFLD. | 2019 | Details |
| A11548 | 30848932 | FASEB J | Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3. | 2019 | Details |
| A11877 | 30700851 | Lab Invest | Impaired mitophagy triggers NLRP3 inflammasome activation during the progression from nonalcoholic fatty liver to nonalcoholic steatohepatitis. | 2019 | Details |
| A16075 | 28584294 | Sci Rep | Evaluation of the effects of L-carnitine on medaka (Oryzias latipes) fatty liver. | 2017 | Details |
| A16656 | 28262196 | Arch Med Res | Serum Chemerin in Obese Children and Adolescents Before and After L-Carnitine Therapy: Relation to Nonalcoholic Fatty Liver Disease and Other Features of Metabolic Syndrome. | 2016 | Details |
| A17335 | 27836788 | Chem Biol Interact | Regression of fibrosis/cirrhosis by Glycine propionyl-l-carnitine treatment in d-Galactosamine induced chronic liver damage. | 2016 | Details |
| A17779 | 27600823 | Am J Physiol Endocrinol Metab | Aerobic capacity and hepatic mitochondrial lipid oxidation alters susceptibility for chronic high-fat diet-induced hepatic steatosis. | 2016 | Details |
| A18527 | 27069868 | Mol Metab | Mitochondrial gene polymorphisms alter hepatic cellular energy metabolism and aggravate diet-induced non-alcoholic steatohepatitis. | 2016 | Details |
| A19077 | 26778339 | Clin Nutr | The odd-carbon medium-chain fatty triglyceride triheptanoin does not reduce hepatic steatosis. | 2015 | Details |
| A20050 | 26190559 | Food Funct | Modulation of tissue fatty acids by L-carnitine attenuates metabolic syndrome in diet-induced obese rats. | 2015 | Details |
| A20077 | 26172853 | Biochim Biophys Acta | Novel role of TLR4 in NAFLD development: Modulation of metabolic enzymes expression. | 2015 | Details |
| A20271 | 26052378 | World J Hepatol | Oxidative stress: New insights on the association of non-alcoholic fatty liver disease and atherosclerosis. | 2015 | Details |
| A21392 | 25352725 | Bioinformation | Data from a randomized and controlled trial of LCarnitine prescription for the treatment for Non- Alcoholic Fatty Liver Disease. | 2014 | Details |
| A21765 | 25061561 | Mol Metab | Methyl-donor supplementation in obese mice prevents the progression of NAFLD, activates AMPK and decreases acyl-carnitine levels. | 2014 | Details |
| A21879 | 24983359 | PLoS One | L-carnitine prevents progression of non-alcoholic steatohepatitis in a mouse model with upregulation of mitochondrial pathway. | 2014 | Details |
| A22519 | 24495527 | Proc Nutr Soc | 'The way to a man's heart is through his gut microbiota'--dietary pro- and prebiotics for the management of cardiovascular risk. | 2014 | Details |
| A22617 | 24407920 | Diabetologia | The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism: a randomised controlled trial. | 2014 | Details |
| A22957 | 24176233 | Nutr Res | Acetyl-L-carnitine and lipoic acid improve mitochondrial abnormalities and serum levels of liver enzymes in a mouse model of nonalcoholic fatty liver disease. | 2013 | Details |
| A23875 | 23410526 | Biochim Biophys Acta | Prevention and reversal of hepatic steatosis with a high-protein diet in mice. | 2013 | Details |
| A25209 | 22093454 | Liver Int | Prevention of free fatty acid-induced hepatic lipotoxicity by carnitine via reversal of mitochondrial dysfunction. | 2011 | Details |
| A25223 | 22082204 | Diabetol Metab Syndr | L-carnitine ameliorated fatty liver in high-calorie diet/STZ-induced type 2 diabetic mice by improving mitochondrial function. | 2011 | Details |
| A25633 | 21621638 | Biochim Biophys Acta | Differential effects of short- and long-term high-fat diet feeding on hepatic fatty acid metabolism in rats. | 2011 | Details |
| A25751 | 21480410 | Phytother Res | A combination of grape extract, green tea extract and L-carnitine improves high-fat diet-induced obesity, hyperlipidemia and non-alcoholic fatty liver disease in mice. | 2011 | Details |
| A26370 | 20578268 | Hepatology | A meta-analysis of randomized trials for the treatment of nonalcoholic fatty liver disease. | 2010 | Details |
| A27155 | 19072834 | Hepatology | Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist. | 2009 | Details |
| A32934 | 27062266 | Hepatol Res | L-carnitine prevents metabolic steatohepatitis in obese diabetic KK-Ay mice. | 2016 | Details |
| A35630 | 20068559 | Am J Gastroenterol | L-carnitine supplementation to diet: a new tool in treatment of nonalcoholic steatohepatitis--a randomized and controlled clinical trial. | 2010 | Details |
| A38217 | 11878015 | Rocz Panstw Zakl Hig | [Effect of some ADH inhibitors on microsomal alcohol oxidizing system activity in vitro]. | 2001 | Details |
| A47359 | 12635862 | Int J Tissue React | Long-term ethanol administration enhances age-dependent modulation of redox state in different brain regions in the rat: protection by acetyl carnitine. | 2002 | Details |
| A48871 | 25954479 | World J Hepatol | Control of oxidative stress in hepatocellular carcinoma: Helpful or harmful? | 2015 | Details |
| A49450 | 35745277 | Nutrients | Maternal One-Carbon Supplement Reduced the Risk of Non-Alcoholic Fatty Liver Disease in Male Offspring. | 2022 | Details |
| A50248 | 35457142 | Int J Mol Sci | Role of Branched-Chain Amino Acid Metabolism in Type 2 Diabetes, Obesity, Cardiovascular Disease and Non-Alcoholic Fatty Liver Disease. | 2022 | Details |
| A51597 | 35788956 | Hepatology | Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction-associated fatty liver disease. | 2022 | Details |
| A51613 | 35660447 | Sci Total Environ | Metabolomics-based safety evaluation of acute exposure to electronic cigarettes in mice. | 2022 | Details |
| A51881 | 33487256 | Clin Nutr ESPEN | Nutraceuticals for the treatment of sarcopenia in chronic liver disease. | 2020 | Details |
| A52049 | 31900483 | Endocrinology | CPT1A-mediated Fat Oxidation, Mechanisms, and Therapeutic Potential. | 2020 | Details |
| A52169 | 30465787 | Toxicol Appl Pharmacol | Clozapine-induced reduction of l-carnitine reabsorption via inhibition/down-regulation of renal carnitine/organic cation transporter 2 contributes to liver lipid metabolic disorder in mice. | 2018 | Details |
| A52257 | 29641977 | Toxicol Appl Pharmacol | Chronic low-dose exposure of nonylphenol alters energy homeostasis in the reproductive system of female rats. | 2018 | Details |
| A52431 | 27197570 | Mol Biosyst | Halofuginone reduces the inflammatory responses of DSS-induced colitis through metabolic reprogramming. | 2016 | Details |
| A52459 | 26920905 | JIMD Rep | ECHS1 Deficiency as a Cause of Severe Neonatal Lactic Acidosis. | 2016 | Details |
| A52574 | 25445284 | Gene | L-Carnitine intake prevents irregular feeding-induced obesity and lipid metabolism disorder. | 2014 | Details |
| A53111 | 12769764 | Curr Pharm Biotechnol | Carnitine metabolism and deficit--when supplementation is necessary? | 2003 | Details |