Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
stats1
stats2
stats3
stats4
Search for:
Polyunsaturated Fatty Acids353 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00148 | 35208265 | Metabolites | Plasma Oxylipin Profile Discriminates Ethnicities in Subjects with Non-Alcoholic Steatohepatitis: An Exploratory Analysis. | 2022 | Details |
| A00296 | 35147302 | Hepatol Commun | Effect of Omega-3 Polyunsaturated Fatty Acids on Lipid Metabolism in Patients With Metabolic Syndrome and NAFLD. | 2022 | Details |
| A00460 | 35072542 | Antioxid Redox Signal | SPECIALIZED PRO-RESOLVING MEDIATORS DERIVED FROM N-3 POLYUNSATURATED FATTY ACIDS: ROLE IN METABOLIC SYNDROME AND RELATED COMPLICATIONS. | 2022 | Details |
| A01075 | 34877270 | World J Clin Cases | Pharmaconutrition strategy to resolve SARS-CoV-2-induced inflammatory cytokine storm in non-alcoholic fatty liver disease: Omega-3 long-chain polyunsaturated fatty acids. | 2021 | Details |
| A01186 | 34836021 | Nutrients | Euphausia pacifica (North Pacific Krill): Review of Chemical Features and Potential Benefits of 8-HEPE against Metabolic Syndrome, Dyslipidemia, NAFLD, and Atherosclerosis. | 2021 | Details |
| A01206 | 34829779 | Biomedicines | Sex-Dependent Effects of Eicosapentaenoic Acid on Hepatic Steatosis in UCP1 Knockout Mice. | 2021 | Details |
| A01257 | 34813379 | Metab Syndr Relat Disord | The Myristic Acid:Docosahexaenoic Acid Ratio Versus the n-6 Polyunsaturated Fatty Acid:n-3 Polyunsaturated Fatty Acid Ratio as Nonalcoholic Fatty Liver Disease Biomarkers. | 2021 | Details |
| A01298 | 34798124 | Biochem Pharmacol | CYP4V2 fatty acid omega hydroxylase, a druggable target for the treatment of metabolic associated fatty liver disease (MAFLD). | 2021 | Details |
| A01348 | 34779464 | Food Funct | MUFA in metabolic syndrome and associated risk factors: is MUFA the opposite side of the PUFA coin? | 2021 | Details |
| A01652 | 34667947 | JHEP Rep | New targets for NAFLD. | 2021 | Details |
| A01785 | 34618982 | FASEB J | Omega-3 carboxylic acids and fenofibrate differentially alter plasma lipid mediators in patients with non-alcoholic fatty liver disease. | 2021 | Details |
| A01936 | 34558838 | Hepatol Commun | Dietary Risks for Liver Mortality in NAFLD: Global Burden of Disease Data. | 2021 | Details |
| A01972 | 34547171 | Liver Int | The role of hepatic lipid composition in obesity-related metabolic disease. | 2021 | Details |
| A02009 | 34532024 | Food Sci Nutr | ω3PUFAs improve hepatic steatosis in postnatal overfed rats and HepG2 cells by inhibiting acetyl-CoA carboxylase. | 2021 | Details |
| A02106 | 34505434 | Se Pu | [Identification of LAMTOR1-regulated metabolites using ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry in malignant transformation of liver inflammation]. | 2021 | Details |
| A02668 | 34291454 | Eur J Clin Invest | Omega-3 phospholipids and obesity-associated NAFLD: Potential mechanisms and therapeutic perspectives. | 2021 | Details |
| A02708 | 34277236 | Cureus | The Significance of the Mediterranean Diet in the Management of Non-Alcoholic Fatty Liver Disease: A Systematic Review. | 2021 | Details |
| A02728 | 34270928 | Cell Metab | FXR activation protects against NAFLD via bile-acid-dependent reductions in lipid absorption. | 2021 | Details |
| A02873 | 34210457 | Rev Gastroenterol Mex (Engl Ed) | Dietary and sociodemographic factors associated with nonalcoholic fatty liver in obese pediatric patients. | 2021 | Details |
| A02942 | 34190160 | Medicine (Baltimore) | A nomogram incorporated lifestyle indicators for predicting nonalcoholic fatty liver disease. | 2021 | Details |
| A03035 | 34156017 | Wiad Lek | INFLUENCE OF COMPLEX TREATMENT ON BIOCHEMICAL BLOOD PARAMETERS OF PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE AND CONCOMITANT PRE-DIABETES. | 2021 | Details |
| A03148 | 34113260 | Front Physiol | Effect of ω-3 Polyunsaturated Fatty Acids-Derived Bioactive Lipids on Metabolic Disorders. | 2021 | Details |
| A03250 | 34072137 | Nutrients | Effect of Dietary Fatty Acids on MicroRNA Expression Related to Metabolic Disorders and Inflammation in Human and Animal Trials. | 2021 | Details |
| A03274 | 34064765 | Cells | Anthracyclins Increase PUFAs: Potential Implications in ER Stress and Cell Death. | 2021 | Details |
| A03364 | 34027340 | JHEP Rep | Genetic predisposition similarities between NASH and ASH: Identification of new therapeutic targets. | 2021 | Details |
| A03391 | 34019353 | Vopr Pitan | [Specialized products for dietary correction of the diet of patients with non-alcoholic steatohepatitis]. | 2021 | Details |
| A03638 | 33923255 | Nutrients | Overview of Non-Alcoholic Fatty Liver Disease (NAFLD) and the Role of Sugary Food Consumption and Other Dietary Components in Its Development. | 2021 | Details |
| A03665 | 33915261 | J Nutr Biochem | Consumption of soybean or olive oil at recommended concentrations increased the intestinal microbiota diversity and insulin sensitivity and prevented fatty liver compared to the effects of coconut oil. | 2021 | Details |
| A03700 | 33898960 | JHEP Rep | Treatment of NAFLD with intermittent calorie restriction or low-carb high-fat diet - a randomised controlled trial. | 2021 | Details |
| A03872 | 33838175 | Food Chem Toxicol | Increased toxicity and retention of perflourooctane sulfonate (PFOS) in humanized CYP2B6-Transgenic mice compared to Cyp2b-null mice is relieved by a high-fat diet (HFD). | 2021 | Details |
| A04230 | 33705952 | J Nutr Biochem | n-3 PUFAs protect against adiposity and fatty liver by promoting browning in postnatally overfed male rats: a role for NRG4. | 2021 | Details |
| A04304 | 33671850 | Nutrients | Omega-3 Polyunsaturated Fatty Acids Prevent Nonalcoholic Steatohepatitis (NASH) and Stimulate Adipogenesis. | 2021 | Details |
| A04762 | 33513444 | Biochim Biophys Acta Mol Cell Biol Lipids | LPIAT1/MBOAT7 contains a catalytic dyad transferring polyunsaturated fatty acids to lysophosphatidylinositol. | 2021 | Details |
| A04840 | 33488295 | Mediators Inflamm | Associations among Dietary Omega-3 Polyunsaturated Fatty Acids, the Gut Microbiota, and Intestinal Immunity. | 2021 | Details |
| A05311 | 33306506 | Am J Gastroenterol | Impact of the Association Between PNPLA3 Genetic Variation and Dietary Intake on the Risk of Significant Fibrosis in Patients With NAFLD. | 2021 | Details |
| A05421 | 33264665 | J Nutr Biochem | Hepatic metabolic adaptation and adipose tissue expansion are altered in mice with steatohepatitis induced by high-fat high sucrose diet. | 2020 | Details |
| A05476 | 33244871 | J Diabetes Investig | Decreased plasma n6 : n3 polyunsaturated fatty acids ratio interacting with high C-peptide promotes non-alcoholic fatty liver disease in type 2 diabetes patients. | 2020 | Details |
| A05707 | 33147705 | Nutrients | Impact of Long-Term Supplementation with Fish Oil in Individuals with Non-Alcoholic Fatty Liver Disease: A Double Blind Randomized Placebo Controlled Clinical Trial. | 2020 | Details |
| A05722 | 33143061 | Nutrients | Cafeteria Diet and High-Fructose Rodent Models of NAFLD Differ in the Metabolism of Important PUFA and Palmitoleic Acid without Additional Influence of Sex. | 2020 | Details |
| A05908 | 33079307 | Arch Pharm Res | Emerging roles of ferroptosis in liver pathophysiology. | 2020 | Details |
| A06112 | 33002297 | Mol Nutr Food Res | Huangjinya Black Tea Alleviates Obesity and Insulin Resistance via Modulating Fecal Metabolome in High-Fat Diet-Fed Mice. | 2020 | Details |
| A06224 | 32962964 | J Clin Lipidol | Effects of a 6-month dietary-induced weight loss on erythrocyte membrane omega-3 fatty acids and hepatic status of subjects with nonalcoholic fatty liver disease: The Fatty Liver in Obesity study. | 2020 | Details |
| A06239 | 32957701 | Biomolecules | Rescue of Hepatic Phospholipid Remodeling Defectin iPLA2β-Null Mice Attenuates Obese but Not Non-Obese Fatty Liver. | 2020 | Details |
| A06312 | 32932796 | Nutrients | Effects of Omega-3 Polyunsaturated Fatty Acid Supplementation on Non-Alcoholic Fatty Liver: A Systematic Review and Meta-Analysis. | 2020 | Details |
| A06347 | 32920973 | Mol Nutr Food Res | Dietary Rapeseed Oil Supplementation Reduces Hepatic Steatosis in Obese Men-A Randomized Controlled Trial. | 2020 | Details |
| A06366 | 32913449 | J Cancer | Reduction of Polyunsaturated Fatty Acids with Tumor Progression in a Lean Non-Alcoholic Steatohepatitis-Associated Hepatocellular Carcinoma Mouse Model. | 2020 | Details |
| A06496 | 32853678 | J Nutr Biochem | N-3 PUFAs inhibited hepatic ER stress induced by feeding of a high-saturated fat diet accompanied by the expression LOX-1. | 2020 | Details |
| A06573 | 32822325 | Orv Hetil | The potential role of organic and conventional yoghurt consumption in the treatment of non-alcoholic fatty liver disease | 2020 | Details |
| A06688 | 32780531 | Mol Nutr Food Res | Lactobacillus rhamnosus GG and Oat Beta-Glucan Regulated Fatty Acid Profiles along the Gut-Liver-Brain Axis of Mice Fed with High Fat Diet and Demonstrated Antioxidant and Anti-Inflammatory Potentials. | 2020 | Details |
| A07052 | 32640331 | Food Chem Toxicol | Analysis of the intricate effects of polyunsaturated fatty acids and polyphenols on inflammatory pathways in health and disease. | 2020 | Details |
| A07225 | 32575640 | Molecules | Effect of Carotenoids from Phaeodactylum tricornutum on Palmitate-Treated HepG2 Cells. | 2020 | Details |
| A07308 | 32545637 | Biology (Basel) | Soluble Epoxide Hydrolase Inhibition in Liver Diseases: A Review of Current Research and Knowledge Gaps. | 2020 | Details |
| A07315 | 32541499 | Medicine (Baltimore) | Efficacy and safety of omega-3 fatty acids on liver-related outcomes in patients with nonalcoholic fatty liver disease: A protocol for a systematic review and meta-analysis. | 2020 | Details |
| A07370 | 32523627 | Therap Adv Gastroenterol | Plasma eicosanoids as noninvasive biomarkers of liver fibrosis in patients with nonalcoholic steatohepatitis. | 2020 | Details |
| A07544 | 32448788 | BMJ Open Diabetes Res Care | Effects of a multifactorial ecosustainable isocaloric diet on liver fat in patients with type 2 diabetes: randomized clinical trial. | 2020 | Details |
| A07746 | 32366600 | J Pharmacol Exp Ther | Ezetimibe Markedly Reduces Hepatic Triglycerides and Cholesterol in Rats Fed on Fish Oil by Increasing the Expression of Cholesterol Efflux Transporters. | 2020 | Details |
| A07776 | 32357561 | Int J Mol Sci | The Molecular and Mechanistic Insights Based on Gut-Liver Axis: Nutritional Target for Non-Alcoholic Fatty Liver Disease (NAFLD) Improvement. | 2020 | Details |
| A07848 | 32335964 | J Gastroenterol Hepatol | Dietary patterns are associated with likelihood of hepatic steatosis among US adults. | 2020 | Details |
| A07912 | 32312974 | Nat Commun | Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance. | 2020 | Details |
| A07983 | 32290535 | Nutrients | Mediterranean Diet Nutrients to Turn the Tide against Insulin Resistance and Related Diseases. | 2020 | Details |
| A08081 | 32255515 | Lipids | Lipid Profiles of Five Essential Phospholipid Preparations for the Treatment of Nonalcoholic Fatty Liver Disease: A Comparative Study. | 2020 | Details |
| A08393 | 32128893 | J Gastroenterol Hepatol | Regulation of lipid-induced macrophage polarization through modulating peroxisome proliferator-activated receptor-gamma activity affects hepatic lipid metabolism via a Toll-like receptor 4/NF-κB signaling pathway. | 2020 | Details |
| A08432 | 32113467 | Lipids Health Dis | Differential effects of Chinese high-fat dietary habits on lipid metabolism: mechanisms and health implications. | 2020 | Details |
| A08523 | 32075238 | Nutrients | Impact of the Co-Administration of N-3 Fatty Acids and Olive Oil Components in Preclinical Nonalcoholic Fatty Liver Disease Models: A Mechanistic View. | 2020 | Details |
| A08617 | 32040876 | Lipids | Gut microbial fatty acid metabolites (KetoA and KetoC) affect the progression of nonalcoholic steatohepatitis and reverse cholesterol transport metabolism in mouse model. | 2020 | Details |
| A08638 | 32036510 | Dig Dis Sci | Omega-3 Fatty Acids and Gut Microbiota: A Reciprocal Interaction in Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A08657 | 32030821 | J Gastroenterol Hepatol | Aging exacerbates high-fat diet-induced steatohepatitis through alteration in hepatic lipid metabolism in mice. | 2020 | Details |
| A08733 | 32007744 | Prostaglandins Leukot Essent Fatty Acids | Iron-induced derangement in hepatic Δ-5 and Δ-6 desaturation capacity and fatty acid profile leading to steatosis: Impact on extrahepatic tissues and prevention by antioxidant-rich extra virgin olive oil. | 2020 | Details |
| A08822 | 31978277 | Mol Nutr Food Res | Lipoatrophy-Associated Insulin Resistance and Hepatic Steatosis are Attenuated by Intake of Diet Rich in Omega 3 Fatty Acids. | 2020 | Details |
| A09058 | 33837698 | Curr Top Membr | Membrane modulatory effects of omega-3 fatty acids: Analysis of molecular level interactions. | 2020 | Details |
| A09139 | 31861497 | Nutrients | Protective Effect of α-Linolenic Acid on Non-Alcoholic Hepatic Steatosis and Interleukin-6 and -10 in Wistar Rats. | 2019 | Details |
| A09618 | 31673534 | Hepatobiliary Surg Nutr | Endogenously increased n-3 PUFA levels in fat-1 transgenic mice do not protect from non-alcoholic steatohepatitis. | 2019 | Details |
| A09642 | 31661783 | Metabolites | A Lipidomic Analysis of Docosahexaenoic Acid (22:6, ω3) Mediated Attenuation of Western Diet Induced Nonalcoholic Steatohepatitis in Male Ldlr -/- Mice. | 2019 | Details |
| A09834 | 31595236 | Porto Biomed J | Dietary cholesterol does not break your heart but kills your liver. | 2019 | Details |
| A09970 | 31540081 | Nutrients | Dietary Supplementation with Hazelnut Oil Reduces Serum Hyperlipidemia and Ameliorates the Progression of Nonalcoholic Fatty Liver Disease in Hamsters Fed a High-Cholesterol Diet. | 2019 | Details |
| A10439 | 31336476 | Diabetes Metab Syndr | Nutrition and physical activity in Asian Indians with non-alcoholic fatty liver: A case control study. | 2019 | Details |
| A10786 | 31193303 | J Adv Res | Beneficial role of bioactive lipids in the pathobiology, prevention, and management of HBV, HCV and alcoholic hepatitis, NAFLD, and liver cirrhosis: A review. | 2018 | Details |
| A10860 | 31152791 | Free Radic Biol Med | Lipidomic biomarkers and mechanisms of lipotoxicity in non-alcoholic fatty liver disease. | 2019 | Details |
| A10908 | 31130652 | Metabolites | Non-Alcoholic Fatty Liver Disease, and the Underlying Altered Fatty Acid Metabolism, Reveals Brain Hypoperfusion and Contributes to the Cognitive Decline in APP/PS1 Mice. | 2019 | Details |
| A11077 | 31055233 | J Nutr Biochem | Fish oil alleviates circadian bile composition dysregulation in male mice with NAFLD. | 2019 | Details |
| A11198 | 31003450 | Nutrients | Oxidative Stress and Non-Alcoholic Fatty Liver Disease: Effects of Omega-3 Fatty Acid Supplementation. | 2019 | Details |
| A11223 | 30987167 | Int J Mol Sci | Ameliorative Effect of Spinach on Non-Alcoholic Fatty Liver Disease Induced in Rats by a High-Fat Diet. | 2019 | Details |
| A11234 | 30981986 | J Nutr Biochem | Western diet consumption through early life induces microvesicular hepatic steatosis in association with an altered metabolome in low birth weight Guinea pigs. | 2019 | Details |
| A11265 | 30968772 | Curr Med Chem | Targeting n-3 Polyunsaturated Fatty Acids in Non-Alcoholic Fatty Liver Disease. | 2020 | Details |
| A11325 | 30937580 | Eur J Nutr | Erythrocyte membrane n-3 polyunsaturated fatty acids are inversely associated with the presence and progression of nonalcoholic fatty liver disease in Chinese adults: a prospective study. | 2019 | Details |
| A11497 | 30871035 | Nutrients | Eicosapentaenoic Acid Improves Hepatic Metabolism and Reduces Inflammation Independent of Obesity in High-Fat-Fed Mice and in HepG2 Cells. | 2019 | Details |
| A11528 | 30856468 | J Nutr Biochem | Tissue-dependent effects of cis-9,trans-11- and trans-10,cis-12-CLA isomers on glucose and lipid metabolism in adult male mice. | 2019 | Details |
| A11626 | 30813440 | Nutrients | Effect of Fish Oil Supplementation on Hepatic and Visceral Fat in Overweight Men: A Randomized Controlled Trial. | 2019 | Details |
| A12034 | 30631760 | Can J Gastroenterol Hepatol | Changes of the Fatty Acid Profile in Erythrocyte Membranes of Patients following 6-Month Dietary Intervention Aimed at the Regression of Nonalcoholic Fatty Liver Disease (NAFLD). | 2018 | Details |
| A12103 | 30601174 | Curr Opin Clin Nutr Metab Care | Omega-3 fatty acids and nonalcoholic fatty liver disease in adults and children: where do we stand? | 2019 | Details |
| A12152 | 30580553 | Crit Rev Food Sci Nutr | n-3 Polyunsaturated fatty acids for the management of alcoholic liver disease: A critical review. | 2018 | Details |
| A12195 | 30567368 | Int J Mol Sci | Effective Food Ingredients for Fatty Liver: Soy Protein β-Conglycinin and Fish Oil. | 2018 | Details |
| A12274 | 30538803 | Oxid Med Cell Longev | Dietary DHA/EPA Ratio Changes Fatty Acid Composition and Attenuates Diet-Induced Accumulation of Lipid in the Liver of ApoE-/- Mice. | 2018 | Details |
| A12303 | 30508576 | Free Radic Biol Med | Increased plasma levels of the lipoperoxyl radical-derived vitamin E metabolite α-tocopheryl quinone are an early indicator of lipotoxicity in fatty liver subjects. | 2018 | Details |
| A12367 | 30483565 | JGH Open | Is non-alcoholic fatty liver disease a reflection of what we eat or simply how much we eat? | 2018 | Details |
| A12517 | 30411763 | Food Funct | Hepatoprotective mechanism of freshwater clam extract alleviates non-alcoholic fatty liver disease: elucidated in vitro and in vivo models. | 2018 | Details |
| A12610 | 30364769 | World J Biol Chem | Mutual interaction between oxidative stress and endoplasmic reticulum stress in the pathogenesis of diseases specifically focusing on non-alcoholic fatty liver disease. | 2018 | Details |
| A12661 | 30340810 | Nutr Res | A review of the pathogenic and therapeutic role of nutrition in pediatric nonalcoholic fatty liver disease. | 2018 | Details |
| A12939 | 30217048 | Nutrients | Aerobic Physical Activity and a Low Glycemic Diet Reduce the AA/EPA Ratio in Red Blood Cell Membranes of Patients with NAFLD. | 2018 | Details |
| A12951 | 30212963 | Medicine (Baltimore) | Omega-3 polyunsaturated fatty acid supplementation and non-alcoholic fatty liver disease: A meta-analysis of randomized controlled trials. | 2018 | Details |