Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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CK-1888 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00146 | 35208576 | Medicina (Kaunas) | The Accuracy of Serum Biomarkers in the Diagnosis of Steatosis, Fibrosis, and Inflammation in Patients with Nonalcoholic Fatty Liver Disease in Comparison to a Liver Biopsy. | 2022 | Details |
| A00278 | 35154523 | Arch Med Sci | Fibroblast growth factor 21 levels and liver inflammatory biomarkers in obese subjects after weight loss. | 2021 | Details |
| A00465 | 35070018 | World J Hepatol | Non-alcoholic steatohepatitis in liver transplant recipients diagnosed by serum cytokeratin 18 and transient elastography: A prospective study. | 2021 | Details |
| A00777 | 34971370 | J Clin Endocrinol Metab | Obesity Modifies the Performance of Fibrosis Biomarkers in Nonalcoholic Fatty Liver Disease. | 2022 | Details |
| A02742 | 34263067 | JGH Open | Noninvasive measure of treatment response in non-alcoholic steatohepatitis: Insights from EMMINENCE and meta-analysis. | 2021 | Details |
| A02762 | 34254372 | Phytother Res | The effect of (Cornus mas L.) fruit extract on liver function among patients with nonalcoholic fatty liver: A double-blind randomized clinical trial. | 2021 | Details |
| A03393 | 34017413 | Am J Transl Res | Correlation of CD3+/CD4+, and serum CK-18 fragment levels with glucose and lipid metabolism in elderly type 2 diabetes patients with nonalcoholic fatty liver disease. | 2021 | Details |
| A03869 | 33838673 | Nutr J | Effects of supplementation with main coffee components including caffeine and/or chlorogenic acid on hepatic, metabolic, and inflammatory indices in patients with non-alcoholic fatty liver disease and type 2 diabetes: a randomized, double-blind, placebo-controlled, clinical trial. | 2021 | Details |
| A04193 | 33720620 | Ter Arkh | [Hepatocellular damage and inflammation in various forms of alcoholic liver disease]. | 2021 | Details |
| A06311 | 32933141 | Int J Mol Sci | Predicting Nonalcoholic Fatty Liver Disease through a Panel of Plasma Biomarkers and MicroRNAs in Female West Virginia Population. | 2020 | Details |
| A06363 | 32915852 | PLoS One | Accuracy of cytokeratin 18 (M30 and M65) in detecting non-alcoholic steatohepatitis and fibrosis: A systematic review and meta-analysis. | 2020 | Details |
| A06649 | 32795119 | Metab Syndr Relat Disord | Omeprazole and Spirulina Platensis Ameliorate Steatohepatitis in Experimental Nonalcoholic Fatty Liver Disease. | 2020 | Details |
| A07975 | 32292439 | Pak J Med Sci | Association of liver biomarkers and cytokeratin-18 in Nonalcoholic fatty liver disease patients. | 2022 | Details |
| A08362 | 32143904 | Pathol Res Pract | The significance of IL-28B and CK-18 M30 levels in the diagnosis of non-alcoholic steatohepatitis in SD rats. | 2020 | Details |
| A09328 | 31789757 | J Clin Gastroenterol | The Role of Noninvasive Tests for Differentiating NASH From NAFL and Diagnosing Advanced Fibrosis Among Patients With NAFLD. | 2020 | Details |
| A09680 | 31651429 | AIDS | Vitamin E is an effective treatment for nonalcoholic steatohepatitis in HIV mono-infected patients. | 2020 | Details |
| A10436 | 31336557 | Diabetes Metab Syndr | Effect of diet-induced weight loss on cytokeratin-18 levels in overweight and obese patients with liver fibrosis. | 2019 | Details |
| A10469 | 31324181 | Nutr J | The effect of total anthocyanin-base standardized (Cornus mas L.) fruit extract on liver function, tumor necrosis factor α, malondealdehyde, and adiponectin in patients with non-alcoholic fatty liver: a study protocol for a double-blind randomized clinical trial. | 2019 | Details |
| A11744 | 30769007 | J Hepatol | The degree of hepatic steatosis associates with impaired cardiac and autonomic function. | 2019 | Details |
| A11818 | 30721572 | Liver Int | Randomized trial comparing effects of weight loss by liraglutide with lifestyle modification in non-alcoholic fatty liver disease. | 2019 | Details |
| A11871 | 30701940 | Ter Arkh | The clinical significance of insulin resistance in non-diabetic patients with early forms of non-alcoholic fatty liver disease. | 2018 | Details |
| A11874 | 30701776 | Ter Arkh | Intrahepatic cholestasis in nonalcoholic fatty liver disease. | 2018 | Details |
| A12201 | 30564000 | J Clin Exp Hepatol | Genetic and Epigenetic Culprits in the Pathogenesis of Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12616 | 30363686 | Int J Hepatol | Relationship between Serum Cytokeratin-18, Control Attenuation Parameter, NAFLD Fibrosis Score, and Liver Steatosis in Nonalcoholic Fatty Liver Disease. | 2018 | Details |
| A12717 | 30317767 | Zhonghua Gan Zang Bing Za Zhi | [Advances in epidemiology and serum markers for the noninvasive diagnosis of nonalcoholic fatty liver disease]. | 2018 | Details |
| A13186 | 30096092 | Eur J Gastroenterol Hepatol | Rifaximin in nonalcoholic fatty liver disease: hit multiple targets with a single shot. | 2018 | Details |
| A13416 | 29989845 | Metab Syndr Relat Disord | Association Between Serum CK-18 Levels and the Degree of Liver Damage in Fructose-Induced Metabolic Syndrome. | 2018 | Details |
| A14496 | 29381754 | PLoS One | Screening for nonalcoholic steatohepatitis by using cytokeratin 18 and transient elastography in HIV mono-infection. | 2018 | Details |
| A14506 | 29377462 | Liver Int | Improvement of hepatic fibrosis and patient-reported outcomes in non-alcoholic steatohepatitis treated with selonsertib. | 2018 | Details |
| A14635 | 29314568 | Liver Int | Genetic determinants of hepatic steatosis and serum cytokeratin-18 fragment levels in Taiwanese children. | 2018 | Details |
| A15216 | 29040984 | Dig Dis | Ability of Cytokeratin-18 Fragments and FIB-4 Index to Diagnose Overall and Mild Fibrosis Nonalcoholic Steatohepatitis in Japanese Nonalcoholic Fatty Liver Disease Patients. | 2017 | Details |
| A15238 | 29028281 | Liver Int | Usefulness of the index of NASH - ION for the diagnosis of steatohepatitis in patients with non-alcoholic fatty liver: An external validation study. | 2017 | Details |
| A15747 | 28730729 | Pediatr Obes | Traffic-related air pollution associations with cytokeratin-18, a marker of hepatocellular apoptosis, in an overweight and obese paediatric population. | 2017 | Details |
| A16224 | 28501537 | Clin Gastroenterol Hepatol | Effects of Exercise on Liver Fat and Metabolism in Alcohol Drinkers. | 2017 | Details |
| A16484 | 28359548 | Gastroenterol Hepatol | Serum cytokeratin-18 fragment levels as noninvasive marker of nonalcoholic steatohepatitis in the chilean population. | 2017 | Details |
| A16504 | 28349067 | Biomed Res Int | A Noninvasive Score Model for Prediction of NASH in Patients with Chronic Hepatitis B and Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16538 | 28326329 | Biomed Res Int | Diagnostic Value of CK-18, FGF-21, and Related Biomarker Panel in Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. | 2017 | Details |
| A17150 | 27956809 | World J Gastroenterol | Disease-specific miR-34a as diagnostic marker of non-alcoholic steatohepatitis in a Chinese population. | 2016 | Details |
| A17572 | 27740519 | Ann Hepatol |  Chemerin, retinol binding protein-4, cytokeratin-18 and transgelin-2 presence in sera of patients with non-alcoholic liver fatty disease. | 2017 | Details |
| A17939 | 27465946 | Zhonghua Gan Zang Bing Za Zhi | [Value of a two-step approach with cytokeratin-18 and controlled attenuation parameter in noninvasive differential diagnosis of nonalcoholic steatohepatitis]. | 2016 | Details |
| A18246 | 27265388 | Aliment Pharmacol Ther | Effects of dark chocolate on NOX-2-generated oxidative stress in patients with non-alcoholic steatohepatitis. | 2016 | Details |
| A18479 | 27102725 | Liver Int | The macrophage activation marker sCD163 is associated with morphological disease stages in patients with non-alcoholic fatty liver disease. | 2016 | Details |
| A19121 | 26748347 | Atherosclerosis | Improvement in non-alcoholic fatty liver disease severity is associated with a reduction in carotid intima-media thickness progression. | 2015 | Details |
| A19394 | 26592838 | Eur Rev Med Pharmacol Sci | The expression of serum M30 and M65 in chronic hepatitis B patients with non-alcoholic fatty liver disease. | 2015 | Details |
| A19554 | 26488474 | Dig Dis | Usefulness of Cytokeratin-18M65 in Diagnosing Non-Alcoholic Steatohepatitis in Japanese Population. | 2015 | Details |
| A19652 | 26436355 | Ann Hepatol | Correlation between serum cytokeratin-18 and the progression or regression of non-alcoholic fatty liver disease. | 2016 | Details |
| A19776 | 26356709 | Medicine (Baltimore) | Epigenetic Modifications in the Biology of Nonalcoholic Fatty Liver Disease: The Role of DNA Hydroxymethylation and TET Proteins. | 2015 | Details |
| A20152 | 26121037 | PLoS One | Combined Serum Biomarkers in Non-Invasive Diagnosis of Non-Alcoholic Steatohepatitis. | 2015 | Details |
| A20285 | 26045704 | Hepat Mon | Clinical values of elevated serum cytokeratin-18 levels in hepatitis: a meta-analysis. | 2015 | Details |
| A20392 | 25994191 | Eur Radiol | Cost-utility analysis of nonalcoholic steatohepatitis screening. | 2015 | Details |
| A20792 | 25732418 | Am J Gastroenterol | Plasma cathepsin D levels: a novel tool to predict pediatric hepatic inflammation. | 2015 | Details |
| A21133 | 25524401 | Hepatology | The impact of phlebotomy in nonalcoholic fatty liver disease: A prospective, randomized, controlled trial. | 2015 | Details |
| A22318 | 24667697 | Clin Chim Acta | The cytokeratin-18 fragment level as a biomarker of nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus. | 2014 | Details |
| A22378 | 24630506 | Arab J Gastroenterol | Apoptotic and anti-apoptotic seromarkers for assessment of disease severity of non-alcoholic steatohepatitis. | 2014 | Details |
| A22763 | 24324749 | PLoS One | Cytokeratin 18, alanine aminotransferase, platelets and triglycerides predict the presence of nonalcoholic steatohepatitis. | 2013 | Details |
| A23068 | 24067262 | Ann Hepatol | Adipocytokines and cytokeratin-18 in patients with nonalcoholic fatty liver disease: Introduction of CHA index. | 2014 | Details |
| A23191 | 23973932 | J Hepatol | Limited value of plasma cytokeratin-18 as a biomarker for NASH and fibrosis in patients with non-alcoholic fatty liver disease. | 2013 | Details |
| A23262 | 23920034 | Clin Gastroenterol Hepatol | Endoscopic duodenal-jejunal bypass liner rapidly improves plasma parameters of nonalcoholic fatty liver disease. | 2013 | Details |
| A23370 | 23837136 | Clin Mol Hepatol | Noninvasive predictors of nonalcoholic steatohepatitis in Korean patients with histologically proven nonalcoholic fatty liver disease. | 2013 | Details |
| A23377 | 23834322 | Hepatol Res | Serum cytokeratin-18 in the diagnosis of non-alcoholic steatohepatitis: A meta-analysis. | 2013 | Details |
| A23397 | 23815500 | Antioxid Redox Signal | Oxidized fatty acids: A potential pathogenic link between fatty liver and type 2 diabetes in obese adolescents? | 2013 | Details |
| A23562 | 23672077 | Rinsho Byori | [Clinical significance of the measurement of serum cytokeratin-18 in patients with non-alcoholic steatohepatitis]. | 2013 | Details |
| A23658 | 23592667 | Obesity (Silver Spring) | Accuracy of prediction scores and novel biomarkers for predicting nonalcoholic fatty liver disease in obese children. | 2013 | Details |
| A23867 | 23418085 | Obesity (Silver Spring) | Interactions of allelic variance of PNPLA3 with nongenetic factors in predicting nonalcoholic steatohepatitis and nonhepatic complications of severe obesity. | 2013 | Details |
| A24256 | 23070083 | J Physiol Pharmacol | A novel pathophysiological-based panel of biomarkers for the diagnosis of nonalcoholic steatohepatitis. | 2012 | Details |
| A24956 | 22314419 | J Hepatol | Non-invasive diagnosis of non-alcoholic steatohepatitis by combined serum biomarkers. | 2012 | Details |
| A25197 | 22098614 | Liver Int | Growth hormone, dehydroepiandrosterone and adiponectin levels in non-alcoholic steatohepatitis: an endocrine signature for advanced fibrosis in obese patients. | 2011 | Details |
| A25850 | 21395631 | Aliment Pharmacol Ther | Enteric-coated cysteamine for the treatment of paediatric non-alcoholic fatty liver disease. | 2011 | Details |
| A26076 | 21145805 | J Hepatol | An apoptosis panel for nonalcoholic steatohepatitis diagnosis. | 2011 | Details |
| A26382 | 20557969 | J Hepatol | Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis. | 2010 | Details |
| A26726 | 19891019 | World J Gastroenterol | Crosstalk between angiogenesis, cytokeratin-18, and insulin resistance in the progression of non-alcoholic steatohepatitis. | 2009 | Details |
| A26885 | 19585618 | Hepatology | Cytokeratin-18 fragment levels as noninvasive biomarkers for nonalcoholic steatohepatitis: a multicenter validation study. | 2009 | Details |
| A27201 | 18995215 | Clin Gastroenterol Hepatol | Cytokeratin 18 fragment levels as a noninvasive biomarker for nonalcoholic steatohepatitis in bariatric surgery patients. | 2008 | Details |
| A27386 | 18500507 | Obes Surg | A novel diagnostic biomarker panel for obesity-related nonalcoholic steatohepatitis (NASH). | 2008 | Details |
| A27574 | 18025069 | Gut | Serum apoptotic caspase activity as a marker of severity in HBeAg-negative chronic hepatitis B virus infection. | 2007 | Details |
| A28817 | 34944770 | Biomedicines | Butyrate Protects against Diet-Induced NASH and Liver Fibrosis and Suppresses Specific Non-Canonical TGF-β Signaling Pathways in Human Hepatic Stellate Cells. | 2021 | Details |
| A31754 | 29913280 | Clin Gastroenterol Hepatol | Emricasan Improves Liver Function in Patients With Cirrhosis and High Model for End-Stage Liver Disease Scores Compared With Placebo. | 2018 | Details |
| A32879 | 27182456 | J Clin Cell Immunol | Role of Serum Biomarkers in Early Detection of Non-Alcoholic Steatohepatitis and Fibrosis in West Virginian Children. | 2016 | Details |
| A34512 | 23275357 | Diabetes Care | The association between hepatic fat content and liver injury in obese children and adolescents: effects of ethnicity, insulin resistance, and common gene variants. | 2012 | Details |
| A34862 | 22404726 | J Viral Hepat | Elevated serum CK18 levels in chronic hepatitis C patients are associated with advanced fibrosis but not steatosis. | 2011 | Details |
| A35003 | 22006541 | Hepatology | A phase 2, randomized, double-blind, placebo-controlled study of GS-9450 in subjects with nonalcoholic steatohepatitis. | 2011 | Details |
| A35005 | 21993925 | Hepatology | Prospective biopsy-controlled evaluation of cell death biomarkers for prediction of liver fibrosis and nonalcoholic steatohepatitis. | 2011 | Details |
| A48915 | 24622872 | Z Gastroenterol | [Cytokeratin 18 as marker for non-invasive diagnosis and prognosis of acute and chronic liver diseases]. | 2014 | Details |
| A49956 | 35583419 | Minerva Med | Non-invasive biochemical markers and surrogate scores in evaluating non-alcoholic steatohepatitis. A narrative review. | 2022 | Details |
| A50579 | 35333917 | J Clin Endocrinol Metab | A Simple Test to Identify the Risk of NASH and Cirrhosis in People With Obesity or Diabetes: The Time to Screen Is Now. | 2022 | Details |
| A51055 | 19821531 | Hepatology | Noninvasive assessment of liver disease severity with liver fat score and CK-18 in NAFLD: Prognostic value of liver fat equation goes beyond hepatic fat estimation. | 2010 | Details |
| A51093 | 35793087 | JAMA Netw Open | Association of Prenatal Exposure to Endocrine-Disrupting Chemicals With Liver Injury in Children. | 2022 | Details |
| A52498 | 26337697 | Obes Surg | Changes in Bile Acid Profile After Laparoscopic Sleeve Gastrectomy are Associated with Improvements in Metabolic Profile and Fatty Liver Disease. | 2016 | Details |