Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Curcumin158 records.
Article ID | PMID | Source | Title | Publish Year | |
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A00373 | 35113098 | Food Funct | Curcumin alleviates hepatic steatosis by improving mitochondrial function in postnatal overfed rats and fatty L02 cells through the SIRT3 pathway. | 2022 | Details |
A00744 | 34981470 | Adv Exp Med Biol | The Effect of Herbal Medicine and Natural Bioactive Compounds on Plasma Adiponectin: A Clinical Review. | 2021 | Details |
A00745 | 34981468 | Adv Exp Med Biol | Curcumin and Piperine Combination for the Treatment of Patients with Non-alcoholic Fatty Liver Disease: A Double-Blind Randomized Placebo-Controlled Trial. | 2021 | Details |
A00803 | 34959992 | Nutrients | Curcumin in Metabolic Health and Disease. | 2021 | Details |
A00850 | 34948230 | Int J Mol Sci | It Is High Time Physicians Thought of Natural Products for Alleviating NAFLD. Is There Sufficient Evidence to Use Them? | 2021 | Details |
A01006 | 34904613 | Food Funct | Steatosis induced by nonylphenol in HepG2 cells and the intervention effect of curcumin. | 2022 | Details |
A01167 | 34847213 | Food Funct | Curcumin supplementation improves biomarkers of oxidative stress and inflammation in conditions of obesity, type 2 diabetes and NAFLD: updating the status of clinical evidence. | 2021 | Details |
A01663 | 34663438 | Diabetol Metab Syndr | The effect of turmeric on lipid profile, malondialdehyde, liver echogenicity and enzymes among patients with nonalcoholic fatty liver disease: a randomized double blind clinical trial. | 2021 | Details |
A01837 | 34599938 | Life Sci | Curcumin activation of nuclear factor E2-related factor 2 gene (Nrf2): Prophylactic and therapeutic effect in nonalcoholic steatohepatitis (NASH). | 2021 | Details |
A02260 | 34444811 | Nutrients | Curcumin and Biochemical Parameters in Metabolic-Associated Fatty Liver Disease (MAFLD)-A Review. | 2021 | Details |
A02278 | 34439562 | Antioxidants (Basel) | Curcumin Suppresses the Lipid Accumulation and Oxidative Stress Induced by Benzo[a]pyrene Toxicity in HepG2 Cells. | 2021 | Details |
A02279 | 34439491 | Antioxidants (Basel) | TRPM2 Non-Selective Cation Channels in Liver Injury Mediated by Reactive Oxygen Species. | 2021 | Details |
A02506 | 34348707 | J Nanobiotechnology | Improving the ameliorative effects of berberine and curcumin combination via dextran-coated bilosomes on non-alcohol fatty liver disease in mice. | 2021 | Details |
A02582 | 34323067 | J Agric Food Chem | Regulation on Citrate Influx and Metabolism through Inhibiting SLC13A5 and ACLY: A Novel Mechanism Mediating the Therapeutic Effects of Curcumin on NAFLD. | 2021 | Details |
A03460 | 33992930 | Eur J Med Chem | Natural products and analogs as preventive agents for metabolic syndrome via peroxisome proliferator-activated receptors: An overview. | 2021 | Details |
A03796 | 33861449 | Adv Exp Med Biol | Beneficial Effects of Plant-Derived Natural Products on Non-alcoholic Fatty Liver Disease. | 2021 | Details |
A03797 | 33861444 | Adv Exp Med Biol | Medicinal Plants and Phytochemicals Regulating Insulin Resistance and Glucose Homeostasis in Type 2 Diabetic Patients: A Clinical Review. | 2021 | Details |
A03798 | 33861434 | Adv Exp Med Biol | The Effect of Curcumin Phytosome on the Treatment of Patients with Non-alcoholic Fatty Liver Disease: A Double-Blind, Randomized, Placebo-Controlled Trial. | 2021 | Details |
A03915 | 33820503 | Mini Rev Med Chem | Mechanism of Natural Drugs on Nonalcoholic Fatty Liver Disease. | 2021 | Details |
A03970 | 33805912 | Int J Mol Sci | Potential of Nutraceutical Supplementation in the Modulation of White and Brown Fat Tissues in Obesity-Associated Disorders: Role of Inflammatory Signalling. | 2021 | Details |
A04097 | 33761646 | Medicine (Baltimore) | The efficacy of novel metabolic targeted agents and natural plant drugs for nonalcoholic fatty liver disease treatment: A PRISMA-compliant network meta-analysis of randomized controlled trials. | 2021 | Details |
A04174 | 33728021 | Oxid Med Cell Longev | Plant-Based Foods and Their Bioactive Compounds on Fatty Liver Disease: Effects, Mechanisms, and Clinical Application. | 2021 | Details |
A04394 | 33636349 | Pharmacol Res | Current innovations in nutraceuticals and functional foods for intervention of non-alcoholic fatty liver disease. | 2021 | Details |
A04514 | 33592199 | Life Sci | Non-alcoholic fatty liver disease: An overview of risk factors, pathophysiological mechanisms, diagnostic procedures, and therapeutic interventions. | 2021 | Details |
A04537 | 33584555 | Front Microbiol | The Therapeutic Efficacy of Curcumin vs. Metformin in Modulating the Gut Microbiota in NAFLD Rats: A Comparative Study. | 2021 | Details |
A04670 | 33546130 | Nutrients | Dietary Polyphenols and Non-Alcoholic Fatty Liver Disease. | 2021 | Details |
A05240 | 33327438 | Int J Mol Sci | Natural Product Heme Oxygenase Inducers as Treatment for Nonalcoholic Fatty Liver Disease. | 2020 | Details |
A05573 | 33203174 | Nutrients | Nutraceutical Properties of Polyphenols against Liver Diseases. | 2020 | Details |
A05695 | 33152943 | Biomed Pharmacother | The effect of adiponectin in the pathogenesis of non-alcoholic fatty liver disease (NAFLD) and the potential role of polyphenols in the modulation of adiponectin signaling. | 2020 | Details |
A06428 | 32884242 | Drug Des Devel Ther | Galangin Improved Non-Alcoholic Fatty Liver Disease in Mice by Promoting Autophagy. | 2020 | Details |
A06555 | 32825982 | J Bodyw Mov Ther | Effects of non-linear resistance training and curcumin supplementation on the liver biochemical markers levels and structure in older women with non-alcoholic fatty liver disease. | 2020 | Details |
A07420 | 32507446 | Complement Ther Med | A pilot study of the effect of curcumin on epigenetic changes and DNA damage among patients with non-alcoholic fatty liver disease: A randomized, double-blind, placebo-controlled, clinical trial. | 2020 | Details |
A07745 | 32366854 | Sci Rep | Novel Combinatorial Regimen of Garcinol and Curcuminoids for Non-alcoholic Steatohepatitis (NASH) in Mice. | 2020 | Details |
A08346 | 32147075 | Complement Ther Med | Effects of curcuminoids on inflammatory status in patients with non-alcoholic fatty liver disease: A randomized controlled trial. | 2020 | Details |
A08777 | 31987259 | Complement Ther Med | The effects of curcumin supplementation on liver function, metabolic profile and body composition in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of randomized controlled trials. | 2019 | Details |
A09248 | 31818232 | Int J Vitam Nutr Res | Efficacy of phytosomal curcumin among patients with non-alcoholic fatty liver disease. | 2019 | Details |
A09257 | 31815784 | Curr Opin Endocrinol Diabetes Obes | Gastrointestinal peptides and nonalcoholic fatty liver disease. | 2020 | Details |
A09301 | 31799714 | Phytother Res | The effects of curcumin supplementation on body mass index, body weight, and waist circumference in patients with nonalcoholic fatty liver disease: A systematic review and dose-response meta-analysis of randomized controlled trials. | 2019 | Details |
A09332 | 31788011 | Nutr Metab (Lond) | Curcumin prevents high-fat diet-induced hepatic steatosis in ApoE-/- mice by improving intestinal barrier function and reducing endotoxin and liver TLR4/NF-κB inflammation. | 2019 | Details |
A09405 | 31758951 | Metabolism | Curcumin analog CUR5-8 ameliorates nonalcoholic fatty liver disease in mice with high-fat diet-induced obesity. | 2019 | Details |
A09509 | 31717261 | Nutrients | Curcumin Ameliorates Nonalcoholic Fatty Liver Disease through Inhibition of O-GlcNAcylation. | 2019 | Details |
A09712 | 31636851 | Toxicol Res | Theracurmin (Highly Bioavailable Curcumin) Prevents High Fat Diet-Induced Hepatic Steatosis Development in Mice. | 2019 | Details |
A09934 | 31554528 | Br J Nutr | Randomised trial of chronic supplementation with a nutraceutical mixture in subjects with non-alcoholic fatty liver disease. | 2020 | Details |
A10286 | 31399137 | BMC Res Notes | Effect of curcumin supplementation on serum expression of select cytokines and chemokines in a female rat model of nonalcoholic steatohepatitis. | 2019 | Details |
A10336 | 31384598 | Clin Nutr Res | Does Turmeric/curcumin Supplementation Change Anthropometric Indices in Patients with Non-alcoholic Fatty Liver Disease? A Systematic Review and Meta-analysis of Randomized Controlled Trials. | 2019 | Details |
A10415 | 31345163 | BMC Gastroenterol | Curcumin and inflammation in non-alcoholic fatty liver disease: a randomized, placebo controlled clinical trial. | 2019 | Details |
A10763 | 31204416 | J Gastrointestin Liver Dis | Effect of Phytosomal Curcumin on Circulating Levels of Adiponectin and Leptin in Patients with Non-Alcoholic Fatty Liver Disease: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. | 2019 | Details |
A10831 | 31168845 | J Cell Biochem | Curcuminoids plus piperine improve nonalcoholic fatty liver disease: A clinical trial. | 2019 | Details |
A10875 | 31145689 | Drug Metab Pers Ther | The effect of curcumin with piperine supplementation on pro-oxidant and antioxidant balance in patients with non-alcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial. | 2019 | Details |
A11041 | 31071511 | Biomed Pharmacother | Therapeutic effects of curcumin and ursodexycholic acid on non-alcoholic fatty liver disease. | 2019 | Details |
A11162 | 31015871 | Pharm Pract (Granada) | The impact of turmeric or its curcumin extract on nonalcoholic fatty liver disease: a systematic review of clinical trials. | 2019 | Details |
A11300 | 30949432 | Integr Med Res | Efficacy of curcumin/turmeric on liver enzymes in patients with non-alcoholic fatty liver disease: A systematic review of randomized controlled trials. | 2018 | Details |
A11400 | 30912307 | Physiol Rep | The long-term protective effects of neonatal administration of curcumin against nonalcoholic steatohepatitis in high-fructose-fed adolescent rats. | 2019 | Details |
A11670 | 30796508 | Eur J Nutr | Effects of phytosomal curcumin on anthropometric parameters, insulin resistance, cortisolemia and non-alcoholic fatty liver disease indices: a double-blind, placebo-controlled clinical trial. | 2019 | Details |
A11727 | 30774801 | Gastroenterol Hepatol Bed Bench | Comparing different non-invasive methods in assessment of the effects of curcumin on hepatic fibrosis in patients with non-alcoholic fatty liver disease. | 2018 | Details |
A11862 | 30705687 | Nutr Metab (Lond) | Nano-curcumin improves glucose indices, lipids, inflammation, and Nesfatin in overweight and obese patients with non-alcoholic fatty liver disease (NAFLD): a double-blind randomized placebo-controlled clinical trial. | 2019 | Details |
A11993 | 30653773 | Phytother Res | Does turmeric/curcumin supplementation improve serum alanine aminotransferase and aspartate aminotransferase levels in patients with nonalcoholic fatty liver disease? A systematic review and meta-analysis of randomized controlled trials. | 2019 | Details |
A12008 | 30647436 | Eur J Clin Nutr | A pilot study of the effect of phospholipid curcumin on serum metabolomic profile in patients with non-alcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial. | 2019 | Details |
A12043 | 30625517 | Biomed Pharmacother | A novel resveratrol-curcumin hybrid, a19, attenuates high fat diet-induced nonalcoholic fatty liver disease. | 2019 | Details |
A12081 | 30610213 | Eur J Clin Nutr | The effects of curcumin supplementation on liver enzymes, lipid profile, glucose homeostasis, and hepatic steatosis and fibrosis in patients with non-alcoholic fatty liver disease. | 2019 | Details |
A12287 | 30529260 | Food Chem Toxicol | Mechanistic insights of hepatoprotective effects of curcumin: Therapeutic updates and future prospects. | 2018 | Details |
A12458 | 30446932 | Hepatol Int | The effects of curcumin on the metabolic parameters of non-alcoholic fatty liver disease: a meta-analysis of randomized controlled trials. | 2018 | Details |
A12504 | 30415581 | J Asian Nat Prod Res | Efficacy of phospholipidated curcumin in nonalcoholic fatty liver disease: a clinical study. | 2018 | Details |
A12506 | 30415544 | J Agric Food Chem | Attenuation by Tetrahydrocurcumin of Adiposity and Hepatic Steatosis in Mice with High-Fat-Diet-Induced Obesity. | 2018 | Details |
A13079 | 30145577 | Ann Hepatol | Salidroside and Curcumin Formula Prevents Liver Injury in Nonalcoholic Fatty Liver Disease in Rats. | 2018 | Details |
A13089 | 30142943 | Nutrients | Nutraceutical Approach to Non-Alcoholic Fatty Liver Disease (NAFLD): The Available Clinical Evidence. | 2018 | Details |
A13381 | 30009570 | Physiol Rep | Curcumin supplementation mitigates NASH development and progression in female Wistar rats. | 2018 | Details |
A13431 | 29976400 | J Food Drug Anal | Tetrahydrocurcumin ameliorates free fatty acid-induced hepatic steatosis and improves insulin resistance in HepG2 cells. | 2018 | Details |
A13627 | 29864915 | Biomed Pharmacother | Dihydrocurcumin ameliorates the lipid accumulation, oxidative stress and insulin resistance in oleic acid-induced L02 and HepG2 cells. | 2018 | Details |
A13636 | 29860219 | Biomed Pharmacother | Curcumin regulates endogenous and exogenous metabolism via Nrf2-FXR-LXR pathway in NAFLD mice. | 2018 | Details |
A13697 | 29802754 | J Dig Dis | Fatty liver mediated by peroxisome proliferator-activated receptor-α DNA methylation can be reversed by a methylation inhibitor and curcumin. | 2018 | Details |
A14563 | 29353208 | Biomed Pharmacother | Natural products berberine and curcumin exhibited better ameliorative effects on rats with non-alcohol fatty liver disease than lovastatin. | 2018 | Details |
A14731 | 29268106 | J Nutr Biochem | Food components with antifibrotic activity and implications in prevention of liver disease. | 2017 | Details |
A15060 | 29114108 | Acta Inform Med | Therapeutic Effects of Curcumin on Ultrasonic Morphological Characteristics of Liver in Patients with Metabolic Syndrome. | 2017 | Details |
A15196 | 29055920 | Ann Hepatol | Curcumin in Hepatobiliary Disease: Pharmacotherapeutic Properties and Emerging Potential Clinical Applications. | 2018 | Details |
A15372 | 28941597 | Metabolism | Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis. | 2017 | Details |
A15410 | 28925892 | Curr Pharm Des | Natural Active Compounds from Plant Food and Chinese Herbal Medicine for Nonalcoholic Fatty Liver Disease. | 2017 | Details |
A15577 | 28836404 | Cell J | Anti-Inflammatory Effects of Curcumin on Insulin Resistance Index, Levels of Interleukin-6, C-Reactive Protein, and Liver Histology in Polycystic Ovary Syndrome-Induced Rats. | 2017 | Details |
A15677 | 28770225 | Biomed Res Int | PEGylated Curcumin Derivative Attenuates Hepatic Steatosis via CREB/PPAR-γ/CD36 Pathway. | 2017 | Details |
A15811 | 28698350 | BMJ Open | Efficacy of nanocurcumin supplementation on insulin resistance, lipids, inflammatory factors and nesfatin among obese patients with non-alcoholic fatty liver disease (NAFLD): a trial protocol. | 2017 | Details |
A15819 | 28694655 | World J Gastroenterol | Antioxidant dietary approach in treatment of fatty liver: New insights and updates. | 2017 | Details |
A16002 | 28618991 | Curr Med Chem | Effects of Polyphenolic Derivatives on Heme Oxygenase-System in Metabolic Dysfunctions. | 2018 | Details |
A16047 | 28595079 | Int Immunopharmacol | Curcumin reduces the risk of chronic kidney damage in mice with nonalcoholic steatohepatitis by modulating endoplasmic reticulum stress and MAPK signaling. | 2017 | Details |
A16095 | 28573069 | World J Gastrointest Pathophysiol | Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice. | 2017 | Details |
A16212 | 28505074 | Nutrients | NAFLD and Atherosclerosis Are Prevented by a Natural Dietary Supplement Containing Curcumin, Silymarin, Guggul, Chlorogenic Acid and Inulin in Mice Fed a High-Fat Diet. | 2017 | Details |
A16432 | 28393690 | Curr Med Chem | Hepatic AMP Kinase as a Potential Target for Treating Nonalcoholic Fatty Liver Disease: Evidence from Studies of Natural Products. | 2018 | Details |
A16521 | 28341485 | Biochim Biophys Acta Gen Subj | Modulation of gut microbiota contributes to curcumin-mediated attenuation of hepatic steatosis in rats. | 2017 | Details |
A16581 | 28297801 | Zhonghua Gan Zang Bing Za Zhi | [Effect of curcumin on intestinal mucosal mechanical barrier in rats with non-alcoholic fatty liver disease]. | 2017 | Details |
A16663 | 28257515 | PLoS One | New evidence for the therapeutic potential of curcumin to treat nonalcoholic fatty liver disease in humans. | 2017 | Details |
A16813 | 28158893 | Drug Res (Stuttg) | Efficacy and Safety of Phytosomal Curcumin in Non-Alcoholic Fatty Liver Disease: A Randomized Controlled Trial. | 2017 | Details |
A16825 | 28146130 | Nutrients | Effects of Natural Products on Fructose-Induced Nonalcoholic Fatty Liver Disease (NAFLD). | 2017 | Details |
A16887 | 28110063 | Int Immunopharmacol | Curcumin ameliorates liver damage and progression of NASH in NASH-HCC mouse model possibly by modulating HMGB1-NF-κB translocation. | 2017 | Details |
A17118 | 27982256 | Acta Cir Bras | Effect of curcumin on visfatin and zinc-α2-glycoprotein in a rat model of non-alcoholic fatty liver disease. | 2016 | Details |
A17293 | 27860427 | J Dig Dis | The role of ADIPOQ methylation in curcumin-administrated experimental nonalcoholic fatty liver disease. | 2016 | Details |
A17558 | 27748192 | Curr Pharm Des | Is There a Role for Curcumin Supplementation in the Treatment of Non-Alcoholic Fatty Liver Disease? The Data Suggest Yes. | 2017 | Details |
A18230 | 27270872 | Phytother Res | Treatment of Non-alcoholic Fatty Liver Disease with Curcumin: A Randomized Placebo-controlled Trial. | 2016 | Details |
A18454 | 27124606 | J Cardiovasc Pharmacol | Curcumin Lowers Serum Lipids and Uric Acid in Subjects With Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial. | 2016 | Details |
A18849 | 26905192 | Tissue Cell | The role of curcumin in streptozotocin-induced hepatic damage and the trans-differentiation of hepatic stellate cells. | 2016 | Details |
A18893 | 26881746 | PLoS One | Hepatoprotective Effect and Synergism of Bisdemethoycurcumin against MCD Diet-Induced Nonalcoholic Fatty Liver Disease in Mice. | 2016 | Details |
A19346 | 26617882 | Int J Clin Exp Pathol | Curcumin prevents the non-alcoholic fatty hepatitis via mitochondria protection and apoptosis reduction. | 2015 | Details |