Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Folic acid68 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A02680 | 34287533 | Arq Gastroenterol | VITAMIN B12 AND HOMOCYSTEINE LEVELS IN PATIENTS WITH NAFLD: A SYSTEMATIC REVIEW AND METANALYSIS. | 2021 | Details |
| A04061 | 33772908 | Biofactors | The role of biofactors in the prevention and treatment of age-related diseases. | 2021 | Details |
| A04498 | 33596128 | Arch Physiol Biochem | Folic acid ameliorates palmitate-induced inflammation through decreasing homocysteine and inhibiting NF-κB pathway in HepG2 cells. | 2021 | Details |
| A06375 | 32908189 | Sci Rep | 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice. | 2020 | Details |
| A06734 | 32765812 | Nutr Res Pract | Folic acid supplementation prevents high fructose-induced non-alcoholic fatty liver disease by activating the AMPK and LKB1 signaling pathways. | 2020 | Details |
| A07486 | 32476787 | World J Gastroenterol | Folic acid attenuates high-fat diet-induced steatohepatitis via deacetylase SIRT1-dependent restoration of PPARα. | 2020 | Details |
| A08475 | 32096475 | Eur Cytokine Netw | Effect of folate supplementation on immunological and autophagy markers in experimental nonalcoholic fatty liver disease. | 2019 | Details |
| A09179 | 31846961 | Lifestyle Genom | One-Carbon Metabolism and Nonalcoholic Fatty Liver Disease: The Crosstalk between Nutrients, Microbiota, and Genetics. | 2019 | Details |
| A10257 | 31408914 | Mol Nutr Food Res | In Utero One-Carbon Metabolism Interplay and Metabolic Syndrome in Cardiovascular Disease Risk Reduction. | 2019 | Details |
| A10953 | 31105018 | Ann Hepatol | "Hepatic toxicity by methotrexate with weekly single doses associated with folic acid in rheumatoid and psoriatic arthritis. What is its real frequency?" | 2019 | Details |
| A11021 | 31080056 | Ann Hepatol | Non-alcoholic fatty liver disease and neurological defects. | 2019 | Details |
| A11671 | 30794826 | Toxicol Appl Pharmacol | Folate receptor-beta expression as a diagnostic target in human & rodent nonalcoholic steatohepatitis. | 2019 | Details |
| A11898 | 30689994 | Eur J Pharmacol | Evaluating the therapeutic potential of one-carbon donors in nonalcoholic fatty liver disease. | 2019 | Details |
| A11991 | 30654845 | Clin Epigenetics | Liver DNA methylation of FADS2 associates with FADS2 genotype. | 2019 | Details |
| A12363 | 30484310 | J Agric Food Chem | Folic Acid Reduced Triglycerides Deposition in Primary Chicken Hepatocytes. | 2018 | Details |
| A12861 | 30252139 | Lipids | Folic Acid Supplementation Attenuates Chronic Hepatic Inflammation in High-Fat Diet Fed Mice. | 2018 | Details |
| A14047 | 29614799 | Nutrients | Folate and B12 Levels Correlate with Histological Severity in NASH Patients. | 2018 | Details |
| A14255 | 29503733 | BMJ Open Gastroenterol | Clinicopathological and immunological characteristics and outcome of concomitant coeliac disease and non-alcoholic fatty liver disease in adults: a large prospective longitudinal study. | 2018 | Details |
| A14343 | 29456073 | Cell Metab | An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans. | 2018 | Details |
| A15341 | 28956816 | Nutrients | Qualitative and Quantitative Evaluation of Dietary Intake in Patients with Non-Alcoholic Steatohepatitis. | 2017 | Details |
| A15797 | 28705466 | Clin Nutr | Serum folic acid levels are associated with the presence and severity of liver steatosis in Chinese adults. | 2017 | Details |
| A16322 | 28460180 | Can J Physiol Pharmacol | Role of folate in nonalcoholic fatty liver disease. | 2017 | Details |
| A16810 | 28160250 | Curr Treat Options Gastroenterol | Thiopurines and Methotrexate Use in IBD Patients in a Biologic Era. | 2017 | Details |
| A17175 | 27930988 | Biomed Pharmacother | Potential involvement of PPAR α activation in diminishing the hepatoprotective effect of fenofibrate in NAFLD: Accuracy of non- invasive panel in determining the stage of liver fibrosis in rats. | 2016 | Details |
| A17744 | 27625763 | Int J Prev Med | Intake of Nutrients, Fiber, and Sugar in Patients with Nonalcoholic Fatty Liver Disease in Comparison to Healthy Individuals. | 2016 | Details |
| A18478 | 27103143 | BMC Genomics | Status of hepatic DNA methylome predetermines and modulates the severity of non-alcoholic fatty liver injury in mice. | 2016 | Details |
| A18901 | 26878785 | J Nutr Biochem | MicroRNA changes, activation of progenitor cells and severity of liver injury in mice induced by choline and folate deficiency. | 2015 | Details |
| A19054 | 26797718 | Obes Surg | Nutritional Status Prior to Laparoscopic Sleeve Gastrectomy Surgery. | 2016 | Details |
| A19709 | 26400185 | Am J Physiol Regul Integr Comp Physiol | Folic acid supplementation during high-fat diet feeding restores AMPK activation via an AMP-LKB1-dependent mechanism. | 2015 | Details |
| A20317 | 26031974 | Clin Med (Lond) | MTHFR 677C/T and 1298A/C mutations and non-alcoholic fatty liver disease. | 2015 | Details |
| A20788 | 25733650 | Am J Clin Nutr | High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice. | 2015 | Details |
| A21240 | 25460293 | Horm Mol Biol Clin Investig | Nutrition: a promising route for prevention and management of obesity-related nonalcoholic fatty liver disease. | 2014 | Details |
| A21356 | 25380481 | Mol Nutr Food Res | Identification of master genes involved in liver key functions through transcriptomics and epigenomics of methyl donor deficiency in rat: relevance to nonalcoholic liver disease. | 2014 | Details |
| A21497 | 25274101 | Br J Nutr | Non-alcoholic fatty liver disease: need for a balanced nutritional source. | 2014 | Details |
| A21513 | 25262992 | Eur J Intern Med | Serum homocysteine levels, oxidative stress and cardiovascular risk in non-alcoholic steatohepatitis. | 2014 | Details |
| A21521 | 25256357 | J Nutr Biochem | Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism. | 2014 | Details |
| A21656 | 25145655 | Toxicol Sci | Systems level metabolic phenotype of methotrexate administration in the context of non-alcoholic steatohepatitis in the rat. | 2014 | Details |
| A21934 | 24955455 | J Gastroenterol Hepatol | Associations between intakes of individual nutrients or whole food groups and non-alcoholic fatty liver disease among Korean adults. | 2014 | Details |
| A22728 | 24353111 | Biofactors | Novel insights on interactions between folate and lipid metabolism. | 2013 | Details |
| A23041 | 24084163 | Mol Genet Metab | Transcriptomic and epigenetic changes in early liver steatosis associated to obesity: effect of dietary methyl donor supplementation. | 2013 | Details |
| A23049 | 24077161 | Orv Hetil | [Hungarian twin studies: results of four decades]. | 2013 | Details |
| A23084 | 24053699 | Asian Pac J Allergy Immunol | Nutrition in early life, immune-programming and allergies: the role of epigenetics. | 2013 | Details |
| A23710 | 23547829 | Nutr J | Plasmatic higher levels of homocysteine in non-alcoholic fatty liver disease (NAFLD). | 2013 | Details |
| A23833 | 23439872 | FASEB J | Strain-dependent dysregulation of one-carbon metabolism in male mice is associated with choline- and folate-deficient diet-induced liver injury. | 2013 | Details |
| A24462 | 22872676 | FASEB J | Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism. | 2012 | Details |
| A24651 | 22648174 | Genes Nutr | Dietary supplementation with methyl donors reduces fatty liver and modifies the fatty acid synthase DNA methylation profile in rats fed an obesogenic diet. | 2012 | Details |
| A24721 | 22561871 | Toxicol Appl Pharmacol | Plasma microRNAs are sensitive indicators of inter-strain differences in the severity of liver injury induced in mice by a choline- and folate-deficient diet. | 2012 | Details |
| A25030 | 22229957 | Int J Food Sci Nutr | Serum vitamin B12 and folate levels in patients with non-alcoholic fatty liver disease. | 2012 | Details |
| A25109 | 22166563 | Ann Hepatol | Serum homocysteine levels in patients with nonalcoholic fatty liver disease. | 2012 | Details |
| A25465 | 21804402 | J Investig Med | Association between serum vitamin B12 levels and the degree of steatosis in patients with nonalcoholic fatty liver disease. | 2011 | Details |
| A26964 | 19450891 | J Hepatol | Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet. | 2009 | Details |
| A27401 | 18465245 | Dig Dis Sci | Association of apolipoprotein E polymorphisms in patients with non-alcoholic steatohepatitis. | 2008 | Details |
| A28308 | 15723740 | Nutrition | Serum folate and homocysteine levels in obese females with non-alcoholic fatty liver. | 2005 | Details |
| A30324 | 32645655 | J Nutr Biochem | The deficit in folate and vitamin B12 triggers liver macrovesicular steatosis and inflammation in rats with dextran sodium sulfate-induced colitis. | 2020 | Details |
| A35416 | 20803414 | Horm Metab Res | Dietary folic acid activates AMPK and improves insulin resistance and hepatic inflammation in dietary rodent models of the metabolic syndrome. | 2010 | Details |
| A36766 | 17311617 | Liver Int | Open-label pilot study of folic acid in patients with nonalcoholic steatohepatitis. | 2007 | Details |
| A37065 | 16535923 | Recenti Prog Med | [Oxidative stress in metabolic syndrome and nonalcoholic steatohepatitis. Is it possible a role for vitamins in clinical practice?]. | 2006 | Details |
| A42238 | 35121169 | Mol Metab | Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction. | 2022 | Details |
| A45307 | 25253983 | World J Gastroenterol | Is increased red cell distribution width an indicating marker of nonalcoholic steatohepatitis and fibrotic stage? | 2014 | Details |
| A46016 | 21538430 | Hepatology | Dietary supplementation with methyl donor groups could prevent nonalcoholic fatty liver. | 2011 | Details |
| A46798 | 15338491 | J Rheumatol | Risk factors for methotrexate-induced abnormal laboratory monitoring results in patients with rheumatoid arthritis. | 2004 | Details |
| A47299 | 18498552 | Alcohol Clin Exp Res | Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liver. | 2008 | Details |
| A47312 | 17616758 | Am J Clin Nutr | Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium. | 2007 | Details |
| A50363 | 35417465 | PLoS One | The regulation of HBP1, SIRT1, and SREBP-1c genes and the related microRNAs in non-alcoholic fatty liver rats: The association with the folic acid anti-steatosis. | 2022 | Details |
| A51171 | 35364359 | Nutr Res | Lower plasma glutathione, choline, and betaine concentrations are associated with fatty liver in postmenopausal women. | 2022 | Details |
| A51663 | 35126841 | World J Hepatol | Metabolic and nutritional triggers associated with increased risk of liver complications in SARS-CoV-2. | 2022 | Details |
| A52787 | 21932846 | J Agric Food Chem | Effects of green tea polyphenol (-)-epigallocatechin-3-gallate on newly developed high-fat/Western-style diet-induced obesity and metabolic syndrome in mice. | 2011 | Details |
| A53120 | 12163688 | J Nutr | The effects of diet, genetics and chemicals on toxicity and aberrant DNA methylation: an introduction. | 2002 | Details |