Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Growth Hormone149 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A00059 | 35238641 | Proc Natl Acad Sci U S A | Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease. | 2022 | Details |
| A00112 | 35216556 | BMC Endocr Disord | Effect of growth hormone therapy on liver enzyme and other cardiometabolic risk factors in boys with obesity and nonalcoholic fatty liver disease. | 2022 | Details |
| A00236 | 35172328 | J Clin Endocrinol Metab | Growth hormone and insulin-like growth factor I regulation of nonalcoholic fatty liver disease. | 2022 | Details |
| A00599 | 35034938 | Endocr J | Associations among FT4 level, FT3/FT4 ratio, and non-alcoholic fatty liver disease in Chinese patients with hypopituitarism. | 2022 | Details |
| A01138 | 34858322 | Front Endocrinol (Lausanne) | The Impact of Dysmetabolic Sarcopenia Among Insulin Sensitive Tissues: A Narrative Review. | 2021 | Details |
| A01856 | 34587729 | Zhonghua Yi Xue Za Zhi | [Clinical features and risk factors of metabolic syndrome in adult hypopituitary patients]. | 2021 | Details |
| A03110 | 34126247 | Endocr Pract | High Prevalence of Nonalcoholic Fatty Liver Disease Among Adolescents and Young Adults With Hypopituitarism due to Growth Hormone Deficiency. | 2021 | Details |
| A03421 | 34006921 | Sci Rep | Delineating tesamorelin response pathways in HIV-associated NAFLD using a targeted proteomic and transcriptomic approach. | 2021 | Details |
| A03837 | 33852720 | Clin Infect Dis | Growth Hormone Releasing Hormone Reduces Circulating Markers of Immune Activation in Parallel with Effects on Hepatic Immune Pathways in Individuals with HIV-infection and Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A04497 | 33596132 | Metab Syndr Relat Disord | When They're Done Growing, Don't Forget They May Still Need Growth Hormone. | 2021 | Details |
| A04785 | 33505943 | Can J Gastroenterol Hepatol | Association between Nonalcoholic Fatty Liver Disease and Endocrinopathies: Clinical Implications. | 2021 | Details |
| A04918 | 33449917 | Endocr Connect | Pathophysiology of NASH in endocrine diseases. | 2021 | Details |
| A05048 | 33395403 | Am J Case Rep | A Case of Hypopituitarism Complicated by Non-Alcoholic Steatohepatitis and Severe Pulmonary Hypertension. | 2021 | Details |
| A05289 | 33311939 | World J Gastroenterol | Pituitary stalk interruption syndrome and liver changes: From clinical features to mechanisms. | 2020 | Details |
| A05653 | 33171865 | Diagnostics (Basel) | Complications of Non-Alcoholic Fatty Liver Disease in Extrahepatic Organs. | 2020 | Details |
| A05775 | 33125080 | J Clin Endocrinol Metab | Relationship of IGF-1 and IGF-Binding Proteins to Disease Severity and Glycemia in Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A05808 | 33112796 | J Endocrinol | GH directly inhibits steatosis and liver injury in a sex-dependent and IGF1-independent manner. | 2021 | Details |
| A06018 | 33037656 | Clin Endocrinol (Oxf) | Effect of recombinant human growth hormone on liver fat content in young adults with nonalcoholic fatty liver disease. | 2020 | Details |
| A06219 | 32963741 | Iran J Basic Med Sci | The role of acylated ghrelin and unacylated ghrelin in the blood and hypothalamus and their interaction with nonalcoholic fatty liver disease. | 2020 | Details |
| A06908 | 32701508 | JCI Insight | Effects of tesamorelin on hepatic transcriptomic signatures in HIV-associated NAFLD. | 2020 | Details |
| A06917 | 32698101 | Growth Horm IGF Res | Growth hormone ameliorates high glucose-induced steatosis on in vitro cultured human HepG2 hepatocytes by inhibiting de novo lipogenesis via ChREBP and FAS suppression. | 2020 | Details |
| A08026 | 32277923 | Mol Metab | Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model. | 2020 | Details |
| A08045 | 32270862 | Clin Infect Dis | Clinical Predictors of Liver Fibrosis Presence and Progression in Human Immunodeficiency Virus-Associated Nonalcoholic Fatty Liver Disease. | 2021 | Details |
| A08197 | 32209476 | Cell Rep | OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation. | 2020 | Details |
| A08448 | 32106111 | JCI Insight | Increased ATP synthesis might counteract hepatic lipid accumulation in acromegaly. | 2020 | Details |
| A08789 | 31984635 | Neurogastroenterol Motil | Ghrelin-insulin-like growth factor-1 axis is activated via autonomic neural circuits in the non-alcoholic fatty liver disease. | 2020 | Details |
| A08917 | 31939706 | Environ Health Perspect | Hepatic Tumor Formation in Adult Mice Developmentally Exposed to Organotin. | 2020 | Details |
| A09783 | 31611038 | Lancet HIV | Effects of tesamorelin on non-alcoholic fatty liver disease in HIV: a randomised, double-blind, multicentre trial. | 2019 | Details |
| A10298 | 31393852 | JCI Insight | Adipocyte JAK2 mediates spontaneous metabolic liver disease and hepatocellular carcinoma. | 2019 | Details |
| A10448 | 31333877 | Clin Diabetes Endocrinol | Natural history of ROHHAD syndrome: development of severe insulin resistance and fatty liver disease over time. | 2019 | Details |
| A10602 | 31275240 | Front Endocrinol (Lausanne) | Transient Elastography and Controlled Attenuation Parameter (CAP) in the Assessment of Liver Steatosis in Severe Adult Growth Hormone Deficiency. | 2019 | Details |
| A10747 | 31212642 | Int J Mol Sci | NAFLD in Some Common Endocrine Diseases: Prevalence, Pathophysiology, and Principles of Diagnosis and Management. | 2019 | Details |
| A10893 | 31136997 | Top Antivir Med | Fatty liver disease in persons with HIV infection. | 2019 | Details |
| A11174 | 31011258 | World J Gastroenterol | Clinical characteristics of non-alcoholic fatty liver disease in Chinese adult hypopituitary patients. | 2019 | Details |
| A12383 | 30474798 | J Endocrinol Invest | Periostin concentrations in childhood-onset craniopharyngioma patients. | 2018 | Details |
| A12419 | 30462610 | Horm Mol Biol Clin Investig | The impact of steatosis on liver regeneration. | 2018 | Details |
| A12564 | 30389231 | Cytokine | Hepatic growth hormone - JAK2 - STAT5 signalling: Metabolic function, non-alcoholic fatty liver disease and hepatocellular carcinoma progression. | 2018 | Details |
| A12652 | 30346875 | Metab Syndr Relat Disord | Growth Hormone Deficiency and Nonalcoholic Fatty Liver Disease with Insights from Humans and Animals: Pediatric Implications. | 2018 | Details |
| A12697 | 30323574 | Clin Interv Aging | Novel insights into the relationship between nonalcoholic fatty liver disease and osteoporosis. | 2018 | Details |
| A12704 | 30321786 | Growth Horm IGF Res | Abrogation of GH action in Kupffer cells results in increased hepatic CD36 expression and exaggerated nonalcoholic fatty liver disease. | 2018 | Details |
| A12770 | 30295789 | Endocrinology | Adult-Onset Hepatocyte GH Resistance Promotes NASH in Male Mice, Without Severe Systemic Metabolic Dysfunction. | 2018 | Details |
| A12962 | 30206761 | Hepatol Int | Metabolic effects of reduced growth hormone action in fatty liver disease. | 2018 | Details |
| A13008 | 30183204 | Neuro Endocrinol Lett | Rapidly progressive non-alcoholic fatty liver disease due to hypopituitarism. Report of 5 cases. | 2018 | Details |
| A13433 | 29975946 | Cell Physiol Biochem | Decreased Hepatic Lactotransferrin Induces Hepatic Steatosis in Chronic Non-Alcoholic Fatty Liver Disease Model. | 2018 | Details |
| A13560 | 29910217 | Intern Med | Hormone-replacement Therapy for Hepatopulmonary Syndrome and NASH Associated with Hypopituitarism. | 2018 | Details |
| A13616 | 29873585 | Metab Syndr Relat Disord | NASH in Nondiabetic Endocrine Disorders. | 2018 | Details |
| A13856 | 29724029 | Int J Mol Sci | Somatotropic Axis Dysfunction in Non-Alcoholic Fatty Liver Disease: Beneficial Hepatic and Systemic Effects of Hormone Supplementation. | 2018 | Details |
| A13890 | 29706895 | Front Physiol | LiverSex Computational Model: Sexual Aspects in Hepatic Metabolism and Abnormalities. | 2018 | Details |
| A13900 | 29702590 | Int J Mol Sci | Insulin-Like Growth Factor (IGF) System in Liver Diseases. | 2018 | Details |
| A14535 | 29364093 | Acta Gastroenterol Belg | The role of insulin - like growth factor - 1 on steatohepatitis. | 2018 | Details |
| A14564 | 29351486 | Am J Physiol Endocrinol Metab | Different physiological roles of insulin receptors in mediating nutrient metabolism in zebrafish. | 2017 | Details |
| A14583 | 29341046 | Horm Metab Res | Reduced Growth Hormone Secretion is Associated with Nonalcoholic Fatty Liver Disease in Obese Children. | 2018 | Details |
| A14852 | 29203511 | Diabetes | Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. | 2017 | Details |
| A15246 | 29025206 | Ann Pediatr Endocrinol Metab | Nonalcoholic fatty liver disease in long-term survivors of childhood-onset craniopharyngioma. | 2017 | Details |
| A15436 | 28913408 | Cell Mol Gastroenterol Hepatol | Hepatocyte-Specific Deletion of Mouse Lamin A/C Leads to Male-Selective Steatohepatitis. | 2017 | Details |
| A15448 | 28902430 | J Bone Miner Res | Reduced Serum IGF-1 Associated With Hepatic Osteodystrophy Is a Main Determinant of Low Cortical but Not Trabecular Bone Mass. | 2017 | Details |
| A15859 | 28678199 | Int J Mol Sci | The Role of Growth Hormone and Insulin-Like Growth Factor-I in the Liver. | 2017 | Details |
| A16377 | 28428362 | J Endocrinol | Hepatic lipid accumulation: cause and consequence of dysregulated glucoregulatory hormones. | 2017 | Details |
| A16507 | 28348479 | World J Gastroenterol | Non-alcoholic fatty liver disease connections with fat-free tissues: A focus on bone and skeletal muscle. | 2017 | Details |
| A16679 | 28250290 | Intern Med | The Relationship between the Growth Hormone/Insulin-like Growth Factor System and the Histological Features of Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A16855 | 28125073 | Clin Transl Gastroenterol | The Association Between IGF-1 Levels and the Histologic Severity of Nonalcoholic Fatty Liver Disease. | 2017 | Details |
| A17262 | 27881164 | BMC Endocr Disord | Administration of anti-receptor activator of nuclear factor-kappa B ligand (RANKL) antibody for the treatment of osteoporosis was associated with amelioration of hepatitis in a female patient with growth hormone deficiency: a case report. | 2016 | Details |
| A17511 | 27762491 | Pediatr Transplant | Resolution of non-alcoholic steatohepatitis after growth hormone replacement in a pediatric liver transplant patient with panhypopituitarism. | 2016 | Details |
| A18344 | 27194386 | Pituitary | Investigating the role of cortisol and growth hormone in fatty liver development: fatty liver index in patients with pituitary adenomas. | 2016 | Details |
| A18819 | 29115108 | Fukuoka Igaku Zasshi | A Probable Case of Burn-out NASH Caused by Panhypopituitarism Secondary to Craniopharyngioma. | 2016 | Details |
| A18860 | 26895665 | J Nutr Biochem | Liver-specific deletion of the signal transducer and activator of transcription 5 gene aggravates fatty liver in response to a high-fat diet in mice. | 2015 | Details |
| A19548 | 26494962 | World J Gastroenterol | Endocrine causes of nonalcoholic fatty liver disease. | 2015 | Details |
| A20141 | 26132376 | Pediatr Obes | Non-Alcoholic Fatty Liver Disease (NAFLD) in children and adolescents with Prader-Willi Syndrome (PWS). | 2015 | Details |
| A20364 | 26015548 | Diabetes | Growth Hormone Inhibits Hepatic De Novo Lipogenesis in Adult Mice. | 2015 | Details |
| A20536 | 25905490 | PLoS One | Higher estimated net endogenous Acid production may be associated with increased prevalence of nonalcoholic Fatty liver disease in chinese adults in Hong Kong. | 2015 | Details |
| A20680 | 25805927 | World J Gastroenterol | Ghrelin-ghrelin O-acyltransferase system in the pathogenesis of nonalcoholic fatty liver disease. | 2015 | Details |
| A20772 | 25744617 | Tohoku J Exp Med | Long-term survival with growth hormone replacement after liver transplantation of pediatric nonalcoholic steatohepatitis complicating acquired hypopituitarism. | 2015 | Details |
| A21028 | 25566190 | Front Endocrinol (Lausanne) | Evolution of hepatic steatosis to fibrosis and adenoma formation in liver-specific growth hormone receptor knockout mice. | 2014 | Details |
| A21399 | 25349437 | Proc Natl Acad Sci U S A | DLK1/PREF1 regulates nutrient metabolism and protects from steatosis. | 2014 | Details |
| A21460 | 25305772 | Arch Iran Med | Systematic review: endocrine abnormalities in patients with liver cirrhosis. | 2014 | Details |
| A21640 | 25163357 | Hepatol Res | Lower levels of insulin-like growth factor-1 standard deviation score are associated with histological severity of non-alcoholic fatty liver disease. | 2014 | Details |
| A21643 | 25157160 | Proc Natl Acad Sci U S A | Ghrelin promotes hepatic lipogenesis by activation of mTOR-PPARγ signaling pathway. | 2014 | Details |
| A21692 | 25116471 | Growth Horm IGF Res | Long-term effects of growth hormone replacement therapy on liver function in adult patients with growth hormone deficiency. | 2014 | Details |
| A22161 | 30736156 | Expert Rev Endocrinol Metab | Insulin-like growth factors (IGF-I and -II): new actors in the development of non-alcoholic fatty liver disease. | 2014 | Details |
| A22255 | 24716226 | J Gastroenterol Hepatol | Relationship between serum circulating insulin-like growth factor-1 and liver fat in the United States. | 2014 | Details |
| A22263 | 24708244 | Endocrinology | GH administration rescues fatty liver regeneration impairment by restoring GH/EGFR pathway deficiency. | 2014 | Details |
| A22282 | 24692138 | Compr Physiol | Energy metabolism in the liver. | 2014 | Details |
| A22422 | 24588719 | J Med Food | A dietary restriction influences the progression but not the initiation of MSG-Induced nonalcoholic steatohepatitis. | 2014 | Details |
| A23398 | 23815295 | Aging Cell | Liver diseases and aging: friends or foes? | 2013 | Details |
| A23439 | 23782652 | Mol Endocrinol | Disruption of JAK2 in adipocytes impairs lipolysis and improves fatty liver in mice with elevated GH. | 2013 | Details |
| A23546 | 23692373 | Diabet Med | Late effects of childhood cancer treatment: severe hypertriglyceridaemia, central obesity, non alcoholic fatty liver disease and diabetes as complications of childhood total body irradiation. | 2013 | Details |
| A24339 | 22986486 | Endocr J | Essential roles of growth hormone (GH) and insulin-like growth factor-I (IGF-I) in the liver. | 2012 | Details |
| A24380 | 22952901 | PLoS One | Association between serum growth hormone levels and nonalcoholic fatty liver disease: a cross-sectional study. | 2012 | Details |
| A24641 | 22659415 | Biochem Biophys Res Commun | GH-independent IGF-I action is essential to prevent the development of nonalcoholic steatohepatitis in a GH-deficient rat model. | 2012 | Details |
| A24677 | 22616493 | Acta Gastroenterol Latinoam | IGF-1 levels in different stages of liver steatosis and its association with metabolic syndrome. | 2012 | Details |
| A24754 | 22535644 | Eur J Endocrinol | Nonalcoholic fatty liver disease in adult hypopituitary patients with GH deficiency and the impact of GH replacement therapy. | 2012 | Details |
| A24850 | 22433286 | Eur J Endocrinol | Hepatic steatosis, GH deficiency and the effects of GH replacement: a Liverpool magnetic resonance spectroscopy study. | 2012 | Details |
| A24987 | 22275361 | J Biol Chem | Hepatocyte-specific deletion of Janus kinase 2 (JAK2) protects against diet-induced steatohepatitis and glucose intolerance. | 2012 | Details |
| A25039 | 22223573 | J Nutr | Long-term dietary potential renal acid load during adolescence is prospectively associated with indices of nonalcoholic fatty liver disease in young women. | 2012 | Details |
| A25197 | 22098614 | Liver Int | Growth hormone, dehydroepiandrosterone and adiponectin levels in non-alcoholic steatohepatitis: an endocrine signature for advanced fibrosis in obese patients. | 2011 | Details |
| A25227 | 22077984 | Clin Endocrinol (Oxf) | Nonalcoholic fatty liver disease is associated with increased GHBP and reduced GH/IGF-I levels. | 2012 | Details |
| A25234 | 22067322 | Endocrinology | Prenatal dexamethasone exposure potentiates diet-induced hepatosteatosis and decreases plasma IGF-I in a sex-specific fashion. | 2011 | Details |
| A25875 | 21364286 | J Clin Invest | Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2. | 2011 | Details |
| A26228 | 20865648 | Horm Metab Res | Metabolic parameters and nonalcoholic fatty liver disease in hypopituitary men. | 2010 | Details |
| A26321 | 20653983 | Lipids Health Dis | Preventive effects of chronic exogenous growth hormone levels on diet-induced hepatic steatosis in rats. | 2010 | Details |