Research Articles
Research articles concerning NAFLD are extracted from PubMed. For each individual article, related therapeutic strategies, targets, drugs and associated diseases in NAFLDkb are presented with knowledge graphs.
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Melatonin59 records.
| Article ID | PMID | Source | Title | Publish Year | |
|---|---|---|---|---|---|
| A01012 | 34903973 | Iran J Pharm Res | Benefits and Risks of Melatonin in Hepatic and Pancreatic Disorders; A Review of Clinical Evidences. | 2021 | Details |
| A01514 | 34712448 | Middle East J Dig Dis | Melatonin Levels in Patients with Nonalcoholic Fatty Liver Disease Compared with Healthy Individuals according to Fibrosis Level. | 2021 | Details |
| A02373 | 34399601 | Int J Immunopathol Pharmacol | Melatonin ameliorates hepatic steatosis by inhibiting NLRP3 inflammasome in db/db mice. | 2022 | Details |
| A02455 | 34365685 | FASEB J | Melatonin induces Nrf2-HO-1 reprogramming and corrections in hepatic core clock oscillations in Non-alcoholic fatty liver disease. | 2021 | Details |
| A02723 | 34273289 | Lancet Gastroenterol Hepatol | Sleep and liver disease: a bidirectional relationship. | 2021 | Details |
| A02786 | 34241659 | Arch Toxicol | Sex-dependent dynamics of metabolism in primary mouse hepatocytes. | 2021 | Details |
| A02846 | 34221262 | Gastroenterol Hepatol Bed Bench | Is melatonin associated with pro-inflammatory cytokine activity and liver fibrosis in non-alcoholic fatty liver disease (NAFLD) patients? | 2021 | Details |
| A03292 | 34058202 | Eur J Pharmacol | The effects of melatonin therapy on the treatment of patients with Non-alcoholic steatohepatitis: A systematic review and Meta-analysis on clinical trial studies. | 2021 | Details |
| A05539 | 33214928 | J Thorac Dis | Sleep disorder in patients with chronic liver disease: a narrative review. | 2020 | Details |
| A06256 | 32951715 | Complement Ther Med | The effect of melatonin on treatment of patients with non-alcoholic fatty liver disease: a randomized double blind clinical trial. | 2020 | Details |
| A06257 | 32951697 | Complement Ther Med | The effect of melatonin supplementation on liver indices in patients with non-alcoholic fatty liver disease: A systematic review and meta-analysis of randomized clinical trials. | 2020 | Details |
| A06924 | 32696189 | Metab Brain Dis | Melatonin regulates neurodegenerative complications associated with NAFLD via enhanced neurotransmission and cellular integrity: a correlational study. | 2020 | Details |
| A07251 | 32566547 | Can J Gastroenterol Hepatol | Effect of Melatonin as an Antioxidant Drug to Reverse Hepatic Steatosis: Experimental Model. | 2020 | Details |
| A08133 | 32235497 | Nutrients | Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis. | 2020 | Details |
| A09694 | 31645151 | Expert Rev Gastroenterol Hepatol | From circadian clocks to non-alcoholic fatty liver disease. | 2019 | Details |
| A09967 | 31541591 | J Pineal Res | Melatonin safeguards against fatty liver by antagonizing TRAFs-mediated ASK1 deubiquitination and stabilization in a β-arrestin-1 dependent manner. | 2019 | Details |
| A10074 | 31500354 | Cells | Melatonin Effects on Non-Alcoholic Fatty Liver Disease Are Related to MicroRNA-34a-5p/Sirt1 Axis and Autophagy. | 2019 | Details |
| A11332 | 30935037 | Nutrients | Melatonin Improves Fatty Liver Syndrome by Inhibiting the Lipogenesis Pathway in Hamsters with High-Fat Diet-Induced Hyperlipidemia. | 2019 | Details |
| A12067 | 30617744 | Pflugers Arch | Ablation of catalase promotes non-alcoholic fatty liver via oxidative stress and mitochondrial dysfunction in diet-induced obese mice. | 2019 | Details |
| A12524 | 30411173 | Sleep Breath | Melatonin prevents chronic intermittent hypoxia-induced injury by inducing sirtuin 1-mediated autophagy in steatotic liver of mice. | 2018 | Details |
| A12693 | 30324559 | Cell Biochem Biophys | Melatonin Modulates lipid Metabolism in HepG2 Cells Cultured in High Concentrations of Oleic Acid: AMPK Pathway Activation may Play an Important Role. | 2018 | Details |
| A13156 | 30112044 | Exp Ther Med | Melatonin alleviates liver steatosis induced by prenatal dexamethasone exposure and postnatal high-fat diet. | 2018 | Details |
| A14337 | 29461236 | Georgian Med News | FEATURES OF EXCRETION OF MELATONIN IN URINE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS AND NON-ALCOHOLIC FATTY LIVER DISEASE WITH MANIFESTATIONS OF FIBROSIS AND ITS RELATIONSHIP WITH CERTAIN METABOLIC AND IMMUNOLOGICAL INDICATORS. | 2018 | Details |
| A15252 | 29023783 | J Cell Physiol | Melatonin application in targeting oxidative-induced liver injuries: A review. | 2017 | Details |
| A15296 | 28981157 | J Pineal Res | Effects of melatonin on fatty liver disease: The role of NR4A1/DNA-PKcs/p53 pathway, mitochondrial fission, and mitophagy. | 2017 | Details |
| A15897 | 28664744 | Bratisl Lek Listy | Therapeutic effects of melatonin and quercetin in improvement of hepatic steatosis in rats through supression of oxidative damage. | 2017 | Details |
| A16219 | 28503495 | Adv Biomed Res | The Effects of Melatonin in Patients with Nonalcoholic Fatty Liver Disease: A Randomized Controlled Trial. | 2017 | Details |
| A17268 | 27876107 | Br J Nutr | Sodium butyrate protects mice from the development of the early signs of non-alcoholic fatty liver disease: role of melatonin and lipid peroxidation. | 2016 | Details |
| A17269 | 27876064 | Lipids Health Dis | Melatonin improves non-alcoholic fatty liver disease via MAPK-JNK/P38 signaling in high-fat-diet-induced obese mice. | 2016 | Details |
| A18634 | 27022943 | Cell Mol Life Sci | Melatonin role preventing steatohepatitis and improving liver transplantation results. | 2016 | Details |
| A19003 | 26824477 | PLoS One | Hepatic Macrosteatosis Is Partially Converted to Microsteatosis by Melatonin Supplementation in ob/ob Mice Non-Alcoholic Fatty Liver Disease. | 2016 | Details |
| A19998 | 26215420 | Biomed Khim | [Intensity of apoptotic processes, aconitate hydratase activity and citrate level in patients with type 2 diabetes mellitus complicated steatohepatitis under application of epifamin at basic therapy]. | 2016 | Details |
| A21070 | 27051920 | Eksp Klin Farmakol | [EFFECTS OF MELATONIN ON THE ACONITATE HYDRATASE ACTIVITY, CONTENT OF LIPID PEROXIDATION PRODUCTS AND SOME NON-ENZYMATIC ANTIOXIDANTS IN THE BLOOD OF PATIENTS WITH TYPE 2 DIABETES MELLITUS COMPLICATED BY STEATOHEPATITIS]. | 2015 | Details |
| A21515 | 25261569 | Dis Model Mech | High-fat diet decreases activity of the oxidative phosphorylation complexes and causes nonalcoholic steatohepatitis in mice. | 2014 | Details |
| A22392 | 24622832 | J Physiol Pharmacol | Effects of treatment with melatonin and tryptophan on liver enzymes, parameters of fat metabolism and plasma levels of cytokines in patients with non-alcoholic fatty liver disease--14 months follow up. | 2014 | Details |
| A23564 | 23671720 | World J Hepatol | Melatonin attenuates high fat diet-induced fatty liver disease in rats. | 2013 | Details |
| A24826 | 22460459 | J Physiol Pharmacol | The effects of long-term melatonin treatment on plasma liver enzymes levels and plasma concentrations of lipids and melatonin in patients with nonalcoholic steatohepatitis: a pilot study. | 2012 | Details |
| A25502 | 21764223 | Med Hypotheses | Full-spectrum antioxidant therapy featuring astaxanthin coupled with lipoprivic strategies and salsalate for management of non-alcoholic fatty liver disease. | 2011 | Details |
| A25583 | 21689150 | J Pineal Res | Melatonin alleviates lipopolysaccharide-induced hepatic SREBP-1c activation and lipid accumulation in mice. | 2011 | Details |
| A25683 | 21549113 | Eur J Pharmacol | Pentoxifylline and melatonin in combination with pioglitazone ameliorate experimental non-alcoholic fatty liver disease. | 2011 | Details |
| A25999 | 21224501 | J Physiol Pharmacol | The pilot study of 3-month course of melatonin treatment of patients with nonalcoholic steatohepatitis: effect on plasma levels of liver enzymes, lipids and melatonin. | 2010 | Details |
| A27969 | 16842545 | J Pineal Res | Melatonin ameliorates nonalcoholic fatty liver induced by high-fat diet in rats. | 2006 | Details |
| A34711 | 22804755 | J Pineal Res | Plasma insulin, leptin, adiponectin, resistin, ghrelin, and melatonin in nonalcoholic steatohepatitis patients treated with melatonin. | 2012 | Details |
| A35129 | 21673361 | J Physiol Pharmacol | Gut clock: implication of circadian rhythms in the gastrointestinal tract. | 2011 | Details |
| A35325 | 21081801 | J Physiol Pharmacol | The effects of L-tryptophan and melatonin on selected biochemical parameters in patients with steatohepatitis. | 2010 | Details |
| A35856 | 19552763 | J Pineal Res | Melatonin ameliorates methionine- and choline-deficient diet-induced nonalcoholic steatohepatitis in rats. | 2009 | Details |
| A43287 | 32061110 | J Pineal Res | Melatonin and circadian rhythms in liver diseases: Functional roles and potential therapies. | 2020 | Details |
| A43537 | 31475778 | J Cell Mol Med | Protective role of melatonin in early-stage and end-stage liver cirrhosis. | 2019 | Details |
| A44136 | 29607540 | J Pineal Res | Melatonin improves insulin resistance and hepatic steatosis through attenuation of alpha-2-HS-glycoprotein. | 2018 | Details |
| A45396 | 24822223 | Biomed Res Int | Melatonin in the regulation of liver steatosis following prenatal glucocorticoid exposure. | 2014 | Details |
| A46061 | 21355880 | J Pineal Res | Melatonin improves mitochondrial respiratory chain activity and liver morphology in ob/ob mice. | 2011 | Details |
| A47082 | 26564773 | Alcohol Alcohol | Melatonin Upregulates the Activity of AMPK and Attenuates Lipid Accumulation in Alcohol-induced Rats. | 2015 | Details |
| A47692 | 33626870 | J Med Chem | Discovery of ACH-000143: A Novel Potent and Peripherally Preferred Melatonin Receptor Agonist that Reduces Liver Triglycerides and Steatosis in Diet-Induced Obese Rats. | 2021 | Details |
| A49497 | 35736447 | Metabolites | Interactions between Tryptophan Metabolism, the Gut Microbiome and the Immune System as Potential Drivers of Non-Alcoholic Fatty Liver Disease (NAFLD) and Metabolic Diseases. | 2022 | Details |
| A49691 | 35668917 | J Inflamm Res | Melatonin Suppresses NLRP3 Inflammasome Activation via TLR4/NF-κB and P2X7R Signaling in High-Fat Diet-Induced Murine NASH Model. | 2022 | Details |
| A50922 | 35377987 | Crit Rev Oncog | Circadian Rhythm and Melatonin in Liver Carcinogenesis: Updates on Current Findings. | 2021 | Details |
| A51348 | 35419738 | Inflammation | Melatonin Attenuates Inflammation, Oxidative Stress, and DNA Damage in Mice with Nonalcoholic Steatohepatitis Induced by a Methionine- and Choline-Deficient Diet. | 2022 | Details |
| A51510 | 35720187 | Oxid Med Cell Longev | Melatonin Alleviates PM2.5-Induced Hepatic Steatosis and Metabolic-Associated Fatty Liver Disease in ApoE-/- Mice. | 2022 | Details |
| A52632 | 24473532 | Menopause | Resveratrol- and melatonin-abated ovariectomy and fructose diet-induced obesity and metabolic alterations in female rats. | 2014 | Details |