Repositioning Candidate Details
| Candidate ID: | R1000 |
| Source ID: | DB06397 |
| Source Type: | investigational |
| Compound Type: | small molecule |
| Compound Name: | Nicaraven |
| Synonyms: | -- |
| Molecular Formula: | C15H16N4O2 |
| SMILES: | CC(CNC(=O)C1=CC=CN=C1)NC(=O)C1=CC=CN=C1 |
| Structure: |
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| DrugBank Description: | -- |
| CAS Number: | 79455-30-4 |
| Molecular Weight: | 284.319 |
| DrugBank Indication: | Investigated for use/treatment in cerebrovascular disease (unspecified). |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | Nicaraven is presently being developed for the treatment of cerebral stroke including subarachnoid hemorrhage. This drug is promising because some data suggest it to have an ability to scavenge the hydroxyl radical under physiological conditions in vivo, while it also has a high permeability through the blood brain barrier. |
| Targets: | -- |
| Inclusion Criteria: | Indication associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I16 | 6713 | Cerebrovascular disease | An vascular disease that is characterized by dysfunction of the blood vessels supplying the brain. http://en.wikipedia.org/wiki/Cerebrovascular_disease, http://www.ncbi.nlm.nih.gov/books/NBK378/ | disease of anatomical entity/ cardiovascular system disease/ vascular disease/cerebrovascular disease | Details |