Repositioning Candidate Details
| Candidate ID: | R1025 |
| Source ID: | DB06472 |
| Source Type: | investigational |
| Compound Type: | small molecule |
| Compound Name: | Fradafiban |
| Synonyms: | Fradafiban |
| Molecular Formula: | C20H21N3O4 |
| SMILES: | NC(=N)C1=CC=C(C=C1)C1=CC=C(OC[C@@H]2C[C@@H](CC(O)=O)C(=O)N2)C=C1 |
| Structure: |
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| DrugBank Description: | -- |
| CAS Number: | 148396-36-5 |
| Molecular Weight: | 367.405 |
| DrugBank Indication: | Investigated for use/treatment in angina. |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | Fradafiban is a glycoprotein IIb/IIIa receptor antagonist. Activation of the platelet glycoprotein (GP IIb/IIIa) receptor on the platelet surface is the final pathway of platelet aggregation that may lead to embolism, which is one on the cause of angina. |
| Targets: | Integrin alpha-IIb; Integrin beta-3 |
| Inclusion Criteria: | Therapeutic strategy associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
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| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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| Diseases ID | DO ID | Disease Name | Definition | Class |
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