Repositioning Candidate Details
| Candidate ID: | R1077 |
| Source ID: | DB06677 |
| Source Type: | investigational |
| Compound Type: | small molecule |
| Compound Name: | Clazosentan |
| Synonyms: | Clazosentan |
| Molecular Formula: | C25H23N9O6S |
| SMILES: | COC1=CC=CC=C1OC1=C(NS(=O)(=O)C2=CC=C(C)C=N2)N=C(N=C1OCCO)C1=CC=NC(=C1)C1=NN=NN1 |
| Structure: |
|
| DrugBank Description: | -- |
| CAS Number: | 180384-56-9 |
| Molecular Weight: | 577.58 |
| DrugBank Indication: | Investigated for use/treatment in strokes. |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | -- |
| Targets: | Endothelin-1 receptor |
| Inclusion Criteria: | Indication associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I16 | 6713 | Cerebrovascular disease | An vascular disease that is characterized by dysfunction of the blood vessels supplying the brain. http://en.wikipedia.org/wiki/Cerebrovascular_disease, http://www.ncbi.nlm.nih.gov/books/NBK378/ | disease of anatomical entity/ cardiovascular system disease/ vascular disease/cerebrovascular disease | Details |