Repositioning Candidate Details
| Candidate ID: | R1078 |
| Source ID: | DB06679 |
| Source Type: | investigational |
| Compound Type: | biotech |
| Compound Name: | Amediplase |
| Synonyms: | Amediplase |
| Molecular Formula: | -- |
| SMILES: | -- |
| DrugBank Description: | Amediplase is a recombinant chimeric plasminogen activator, consisting of the kringle 2 domain from the A-chain of tissue plasminogen activator (t-PA) and the carboxy terminal region of pro-urokinase. |
| CAS Number: | 151912-11-7 |
| Molecular Weight: | |
| DrugBank Indication: | Investigated for use/treatment in myocardial infarction and thrombosis. |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | -- |
| Targets: | -- |
| Inclusion Criteria: | Indication associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I08 | 114 | Cardiovascular system disease | A disease of anatomical entity which occurs in the blood, heart, blood vessels or the lymphatic system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells or lymph to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. http://en.wikipedia.org/wiki/Circulatory_system | disease of anatomical entity | Details |