Repositioning Candidate Details
| Candidate ID: | R1249 |
| Source ID: | DB09219 |
| Source Type: | approved |
| Compound Type: | small molecule |
| Compound Name: | Bisoxatin |
| Synonyms: | Bisoxatin |
| Molecular Formula: | C20H15NO4 |
| SMILES: | OC1=CC=C(C=C1)C1(OC2=CC=CC=C2NC1=O)C1=CC=C(O)C=C1 |
| Structure: |
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| DrugBank Description: | Bisoxatin is a stimulant laxative which increases peristalsis and inhibits absorbtion of water and ions in the intestine . It is marketed in Belgium under the tradename Wylaxine and used for the treatment of constipation and for preparation of the colon for surgical procedures. |
| CAS Number: | 17692-24-9 |
| Molecular Weight: | 333.343 |
| DrugBank Indication: | For use in the treatment of constipation in the absence of bowel obstruction and for surgical preparation of the colon . |
| DrugBank Pharmacology: | Bisoxatin is a stimulant laxative which increases peristalsis and inhibits the absorbtion of water and ions in the intestine . This increases the water content of the feces and increases its movement through the intestine. |
| DrugBank MoA: | The precise mechanism of the bisoxatin's stimulant effect and inhibition of water and ion movement is unknown. |
| Targets: | -- |
| Inclusion Criteria: | Indication associated |

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