Repositioning Candidate Details
| Candidate ID: | R1286 |
| Source ID: | DB09290 |
| Source Type: | investigational |
| Compound Type: | small molecule |
| Compound Name: | Ramosetron |
| Synonyms: | Ramosetron |
| Molecular Formula: | C17H17N3O |
| SMILES: | CN1C=C(C(=O)[C@@H]2CCC3=C(C2)N=CN3)C2=C1C=CC=C2 |
| Structure: |
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| DrugBank Description: | Ramosetron is a _serotonin 5-HT3 receptor antagonist_ commonly employed to treat nausea and vomiting, in addition to certain diarrheal conditions. It is believed to have higher potency and longer antiemetic action than other 1st generation 5-HT3 antagonists such as ondansetron. Currently, ramosetron is only approved for use Japan and in certain Southeast Asian countries. |
| CAS Number: | 132036-88-5 |
| Molecular Weight: | 279.343 |
| DrugBank Indication: | For the treatment of nausea and vomiting and diarrhea-predominant irritable bowel syndrome in males. |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | -- |
| Targets: | 5-hydroxytryptamine receptor 3A antagonist |
| Inclusion Criteria: | Indication associated |
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| Diseases ID | DO ID | Disease Name | Definition | Class |
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