Repositioning Candidate Details
| Candidate ID: | R1306 |
| Source ID: | DB09394 |
| Source Type: | approved |
| Compound Type: | small molecule |
| Compound Name: | Phosphoric acid |
| Synonyms: | -- |
| Molecular Formula: | H3O4P |
| SMILES: | OP(O)(O)=O |
| Structure: |
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| DrugBank Description: | Phosphoric Acid is a colorless, odorless phosphorus-containing inorganic acid. Phosphoric acid is a sequestering agent which binds many divalent cations, including Fe++, Cu++, Ca++, and Mg++. |
| CAS Number: | 7664-38-2 |
| Molecular Weight: | 97.9952 |
| DrugBank Indication: | Phosphoric acid is used in dentistry and orthodontics as an etching solution, to clean and roughen the surfaces of teeth where dental appliances or fillings will be placed. |
| DrugBank Pharmacology: | Transport of phosphate from the gut lumen is an active, energy-dependent process that is modified by several factors. ... Vitamin D stimulates phosphate absorption, an effect reported to precede its action on calcium ion transport. |
| DrugBank MoA: | Phosphate supplementation of the diet of rodents has been shown to lead to reduction in the incidence of dental caries and different phosphates have different powers in reducing the cariogenic potential of the carbohydrates in a diet. Phosphate supplements seem to exert their cariostatic effect on the tooth surface either directly during eating or by excretion in the saliva. |
| Targets: | -- |
| Inclusion Criteria: | Therapeutic strategy associated |
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