Repositioning Candidate Details
| Candidate ID: | R1327 |
| Source ID: | DB11068 |
| Source Type: | approved |
| Compound Type: | small molecule |
| Compound Name: | Selenic acid |
| Synonyms: | -- |
| Molecular Formula: | H2O4Se |
| SMILES: | O[Se](O)(=O)=O |
| Structure: |
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| DrugBank Description: | Selenic acid is an organic compound with the chemical formula H2SeO4. It may be found in over-the-counter daily dietary supplements as a source of , an essential trace mineral for human health. |
| CAS Number: | 7783-08-6 |
| Molecular Weight: | 144.97 |
| DrugBank Indication: | Indicated for use as a nutritional supplement. |
| DrugBank Pharmacology: | is an essential trace mineral that plays a critical role in antioxidant actions, anti-inflammatory effects, immune function, and the production of active thyroid hormone . |
| DrugBank MoA: | is a constituent of selenoproteins thus has structural and enzymatic roles. It acts as an antioxidant via the actions of selenoproteins for protection against oxidative stress, and acts as a catayst for the production of active thyroid hormone . It may also play a role in sperm motility . |
| Targets: | -- |
| Inclusion Criteria: | Therapeutic strategy associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs | |
|---|---|---|---|---|---|
| S04 | Anti-oxidative stress | oxidative stress | α-tocopherol: antioxidant | Vitamin E | Details |
| S05 | Anti-inflammatory | inflammatory | Bile acid; TNF-a inhibitor; Dual PPAR-α and -δ agonists; Toll-Like Receptor; (TLR)-4 antagonist; Caspase inhibitor; ASK-1 inhibitor | Ursodeoxycholic Acid; Pentoxifylline; Elafibranor; JKB-121; Emricasan; Selonsertib; | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class |
|---|