Repositioning Candidate Details
| Candidate ID: | R0618 |
| Source ID: | DB04818 |
| Source Type: | withdrawn |
| Compound Type: | small molecule |
| Compound Name: | Iproniazid |
| Synonyms: | Iproniazid |
| Molecular Formula: | C9H13N3O |
| SMILES: | CC(C)NNC(=O)C1=CC=NC=C1 |
| Structure: |
|
| DrugBank Description: | Withdrawn from the Canadian market in July 1964 due to interactions with food products containing tyrosine. |
| CAS Number: | 54-92-2 |
| Molecular Weight: | 179.219 |
| DrugBank Indication: | For the treatment of depression (originally intended to treat tuberculosis). |
| DrugBank Pharmacology: | Iproniazid is a monoamine oxidase inhibitor (MAOI) that was developed as the first anti-depressant. |
| DrugBank MoA: | -- |
| Targets: | -- |
| Inclusion Criteria: | Indication associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I09 | 104 | Bacterial infectious disease | A disease by infectious agent that results_in infection, has_material_basis_in Bacteria. http://en.wikipedia.org/wiki/Pathogenic_bacteria | disease by infectious agent | Details |
| I17 | 1596 | Mental depression | Mental depression | disease of mental health/ cognitive disorder/ mood disorder | Details |