Repositioning Candidate Details
| Candidate ID: | R0621 |
| Source ID: | DB04836 |
| Source Type: | illicit; withdrawn |
| Compound Type: | small molecule |
| Compound Name: | Amineptine |
| Synonyms: | Amineptine |
| Molecular Formula: | C22H27NO2 |
| SMILES: | OC(=O)CCCCCCNC1C2=CC=CC=C2CCC2=CC=CC=C12 |
| Structure: |
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| DrugBank Description: | The Food and Drug Administration suspended the marketing authorisation for Survector in 1999 and France withdrew it from the market, however several developing countries continued to produce it up until 2005. |
| CAS Number: | 57574-09-1 |
| Molecular Weight: | 337.463 |
| DrugBank Indication: | For the treatment of depression. |
| DrugBank Pharmacology: | Amineptine is an atypical tricyclic antidepressant. |
| DrugBank MoA: | Amineptine selectively inhibits the reuptake of dopamine and to a lesser extent norepinephrine, thus exerting a powerful and fast-acting antidepressant effect. |
| Targets: | Sodium-dependent noradrenaline transporter; Sodium-dependent serotonin transporter |
| Inclusion Criteria: | Indication associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
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