Repositioning Candidate Details
| Candidate ID: | R0836 |
| Source ID: | DB05607 |
| Source Type: | investigational |
| Compound Type: | small molecule |
| Compound Name: | PRX-08066 |
| Synonyms: | -- |
| Molecular Formula: | C23H21ClFN5O4S |
| SMILES: | OC(=O)\C=C\C(O)=O.FC1=C(C=C(CN2CCC(CC2)NC2=C3C=C(Cl)SC3=NC=N2)C=C1)C#N |
| Structure: |
|
| DrugBank Description: | -- |
| CAS Number: | -- |
| Molecular Weight: | 517.96 |
| DrugBank Indication: | Investigated for use/treatment in chronic obstructive pulmonary disease (COPD) and pulmonary hypertension. |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | -- |
| Targets: | 5-hydroxytryptamine receptor 2B antagonist |
| Inclusion Criteria: | Indication associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I12 | 10763 | Hypertension | An artery disease characterized by chronic elevated blood pressure in the arteries. https://en.wikipedia.org/wiki/Hypertension, https://www.ncbi.nlm.nih.gov/pubmed/24352797 | disease of anatomical entity/ cardiovascular system disease/vascular disease/ artery disease | Details |