Repositioning Candidate Details
| Candidate ID: | R0838 |
| Source ID: | DB05631 |
| Source Type: | investigational |
| Compound Type: | small molecule |
| Compound Name: | ALT-2074 |
| Synonyms: | -- |
| Molecular Formula: | C10H13NSe |
| SMILES: | CC1(C)CN[Se]C2=CC=CC=C12 |
| Structure: |
|
| DrugBank Description: | An organoselenium drug previously studied by Oxis International in Phase-II clinical trials for ulcerative colitis patients. Some indications of efficacy were demonstrated. BXT-51072 has enthusiastic endorsement for treatment in cardiovascular indications, primarily because of its ability to mimic the function of glutathione peroxidase. |
| CAS Number: | 173026-17-0 |
| Molecular Weight: | 226.18 |
| DrugBank Indication: | Investigated for use/treatment in cardiovascular disorders and diabetes mellitus type 1 and 2. |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | -- |
| Targets: | -- |
| Inclusion Criteria: | Indication associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
|---|
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I05 | 9352 | Type 2 diabetes mellitus | A diabetes that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin. http://en.wikipedia.org/wiki/Diabetes, http://en.wikipedia.org/wiki/Diabetes_mellitus_type_2 | disease of metabolism/inherited metabolic disorder/ carbohydrate metabolic disorder/glucose metabolism disease/diabetes/ diabetes mellitus | Details |