Repositioning Candidate Details
| Candidate ID: | R0897 |
| Source ID: | DB05905 |
| Source Type: | investigational |
| Compound Type: | small molecule |
| Compound Name: | TD-2749 |
| Synonyms: | -- |
| Molecular Formula: | C26H38N6O2 |
| SMILES: | CC(C)N1N=C(C(=O)N[C@@H]2C[C@@H]3CC[C@H](C2)N3CCN2CCN(CC2)C(C)=O)C2=CC=CC=C12 |
| Structure: |
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| DrugBank Description: | TD-2749 is selective 5-HT4 agonists discovered by Theravance through the application of multivalent drug design in a drug discovery program dedicated to finding new medicines for GI motility disorders such as chronic constipation, constipation-predominant irritable bowel syndrome (C-IBS), opioid-induced constipation, functional dyspepsia and diabetic gastroparesis. |
| CAS Number: | 863248-59-3 |
| Molecular Weight: | 466.63 |
| DrugBank Indication: | Investigated for use/treatment in constipation, gastrointestinal diseases and disorders (miscellaneous), gastroparesis, and irritable bowel syndrome (IBS). |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | -- |
| Targets: | 5-hydroxytryptamine receptor 4 |
| Inclusion Criteria: | Indication associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs |
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| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
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