Repositioning Candidate Details
| Candidate ID: | R0975 |
| Source ID: | DB06297 |
| Source Type: | investigational |
| Compound Type: | small molecule |
| Compound Name: | LX-2931 |
| Synonyms: | -- |
| Molecular Formula: | C9H15N3O5 |
| SMILES: | C\C(=N/O)C1=NC=C(N1)[C@@H](O)[C@H](O)[C@H](O)CO |
| Structure: |
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| DrugBank Description: | -- |
| CAS Number: | 948840-25-3 |
| Molecular Weight: | 245.235 |
| DrugBank Indication: | Investigated for use/treatment in rheumatoid arthritis, inflammatory disorders (unspecified), and autoimmune diseases. |
| DrugBank Pharmacology: | -- |
| DrugBank MoA: | -- |
| Targets: | -- |
| Inclusion Criteria: | Indication associated |
| Strategy ID | Strategy | Synonyms | Related Targets | Related Drugs | |
|---|---|---|---|---|---|
| S05 | Anti-inflammatory | inflammatory | Bile acid; TNF-a inhibitor; Dual PPAR-α and -δ agonists; Toll-Like Receptor; (TLR)-4 antagonist; Caspase inhibitor; ASK-1 inhibitor | Ursodeoxycholic Acid; Pentoxifylline; Elafibranor; JKB-121; Emricasan; Selonsertib; | Details |
| Target ID | Target Name | GENE | Action | Class | UniProtKB ID | Entry Name |
|---|
| Diseases ID | DO ID | Disease Name | Definition | Class | |
|---|---|---|---|---|---|
| I15 | 1290 | Bone disease | A connective tissue disease that affects the structure or development of bone or causes an impairment of normal bone function. http://en.wikipedia.org/wiki/Bone_disease | disease of anatomical entity/ musculoskeletal system disease/connective tissue disease | Details |