Repositioning Candidates
Repositioning candidates for NAFLD are derived from DrugBank which fall into three categories: therapeutic strategy-associated, target-associated, and indication-associated candidates. For each candidate, detailed properties are extracted from DrugBank, and related strategies, target and NAFLD-associated disease in NAFLDkb are presented with knowledge graphs.
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inflammatory457 records.
| Candidate ID | Source ID | Source Type | Compound Type | Candidate Name | Inclusion Criteria | |
|---|---|---|---|---|---|---|
| R0002 | DB00003 | approved | biotech | Dornase alfa | Therapeutic strategy associated | Details |
| R0003 | DB00005 | approved; investigational | biotech | Etanercept | Therapeutic strategy associated | Details |
| R0009 | DB00026 | approved | biotech | Anakinra | Therapeutic strategy associated | Details |
| R0010 | DB00028 | approved; investigational | biotech | Human immunoglobulin G | Indication associated | Details |
| R0014 | DB00043 | approved; investigational | biotech | Omalizumab | Therapeutic strategy associated | Details |
| R0017 | DB00051 | approved; experimental | biotech | Adalimumab | Therapeutic strategy associated | Details |
| R0020 | DB00065 | approved | biotech | Infliximab | Therapeutic strategy associated | Details |
| R0022 | DB00073 | approved | biotech | Rituximab | Therapeutic strategy associated | Details |
| R0027 | DB00091 | approved; investigational; vet_approved | small molecule | Cyclosporine | Therapeutic strategy associated | Details |
| R0031 | DB00108 | approved; investigational | biotech | Natalizumab | Therapeutic strategy associated | Details |
| R0034 | DB00117 | investigational; nutraceutical | small molecule | Histidine | Therapeutic strategy associated | Details |
| R0038 | DB00125 | investigational; nutraceutical | small molecule | Arginine | Therapeutic strategy associated | Details |
| R0043 | DB00132 | approved; investigational; nutraceutical | small molecule | alpha-Linolenic acid | Therapeutic strategy associated | Details |
| R0046 | DB00138 | approved; nutraceutical | small molecule | Cystine | Therapeutic strategy associated | Details |
| R0054 | DB00154 | investigational; nutraceutical | small molecule | Dihomo-gamma-linolenic acid | Therapeutic strategy associated | Details |
| R0056 | DB00159 | approved; nutraceutical | small molecule | Icosapent | Therapeutic strategy associated | Details |
| R0057 | DB00169 | approved; nutraceutical | small molecule | Cholecalciferol | Therapeutic strategy associated | Details |
| R0066 | DB00180 | approved; investigational | small molecule | Flunisolide | Therapeutic strategy associated | Details |
| R0067 | DB00181 | approved | small molecule | Baclofen | Therapeutic strategy associated | Details |
| R0071 | DB00193 | approved; investigational | small molecule | Tramadol | Therapeutic strategy associated | Details |
| R0073 | DB00199 | approved; investigational; vet_approved | small molecule | Erythromycin | Indication associated | Details |
| R0079 | DB00210 | approved | small molecule | Adapalene | Therapeutic strategy associated | Details |
| R0083 | DB00216 | approved; investigational | small molecule | Eletriptan | Therapeutic strategy associated | Details |
| R0086 | DB00223 | approved | small molecule | Diflorasone | Therapeutic strategy associated | Details |
| R0092 | DB00240 | approved | small molecule | Alclometasone | Therapeutic strategy associated | Details |
| R0093 | DB00244 | approved | small molecule | Mesalazine | Therapeutic strategy associated | Details |
| R0094 | DB00250 | approved; investigational | small molecule | Dapsone | Therapeutic strategy associated | Details |
| R0095 | DB00253 | approved | small molecule | Medrysone | Therapeutic strategy associated | Details |
| R0100 | DB00277 | approved | small molecule | Theophylline | Therapeutic strategy associated | Details |
| R0103 | DB00281 | approved; vet_approved | small molecule | Lidocaine | Therapeutic strategy associated | Details |
| R0107 | DB00288 | approved | small molecule | Amcinonide | Therapeutic strategy associated | Details |
| R0112 | DB00313 | approved; investigational | small molecule | Valproic acid | Therapeutic strategy associated | Details |
| R0114 | DB00324 | approved; investigational | small molecule | Fluorometholone | Therapeutic strategy associated | Details |
| R0117 | DB00328 | approved; investigational | small molecule | Indomethacin | Therapeutic strategy associated | Details |
| R0121 | DB00337 | approved; investigational | small molecule | Pimecrolimus | Therapeutic strategy associated | Details |
| R0122 | DB00341 | approved | small molecule | Cetirizine | Therapeutic strategy associated | Details |
| R0128 | DB00356 | approved | small molecule | Chlorzoxazone | Therapeutic strategy associated | Details |
| R0134 | DB00374 | approved; investigational | small molecule | Treprostinil | Therapeutic strategy associated | Details |
| R0136 | DB00380 | approved; withdrawn | small molecule | Dexrazoxane | Therapeutic strategy associated | Details |
| R0139 | DB00394 | approved; investigational | small molecule | Beclomethasone dipropionate | Therapeutic strategy associated | Details |
| R0150 | DB00443 | approved; vet_approved | small molecule | Betamethasone | Therapeutic strategy associated | Details |
| R0155 | DB00461 | approved | small molecule | Nabumetone | Therapeutic strategy associated | Details |
| R0157 | DB00465 | approved | small molecule | Ketorolac | Therapeutic strategy associated | Details |
| R0159 | DB00469 | approved | small molecule | Tenoxicam | Therapeutic strategy associated | Details |
| R0163 | DB00480 | approved | small molecule | Lenalidomide | Therapeutic strategy associated | Details |
| R0165 | DB00482 | approved; investigational | small molecule | Celecoxib | Therapeutic strategy associated | Details |
| R0166 | DB00484 | approved | small molecule | Brimonidine | Therapeutic strategy associated | Details |
| R0172 | DB00500 | approved | small molecule | Tolmetin | Therapeutic strategy associated | Details |
| R0179 | DB00533 | approved; investigational; withdrawn | small molecule | Rofecoxib | Therapeutic strategy associated | Details |
| R0186 | DB00547 | approved | small molecule | Desoximetasone | Therapeutic strategy associated | Details |
| R0187 | DB00549 | approved; investigational | small molecule | Zafirlukast | Therapeutic strategy associated | Details |
| R0188 | DB00554 | approved; investigational | small molecule | Piroxicam | Therapeutic strategy associated | Details |
| R0190 | DB00557 | approved | small molecule | Hydroxyzine | Therapeutic strategy associated | Details |
| R0194 | DB00563 | approved | small molecule | Methotrexate | Therapeutic strategy associated | Details |
| R0197 | DB00573 | approved | small molecule | Fenoprofen | Target associated | Details |
| R0200 | DB00580 | approved; investigational; withdrawn | small molecule | Valdecoxib | Therapeutic strategy associated | Details |
| R0202 | DB00586 | approved; vet_approved | small molecule | Diclofenac | Therapeutic strategy associated | Details |
| R0203 | DB00587 | experimental | small molecule | Cinalukast | Therapeutic strategy associated | Details |
| R0205 | DB00591 | approved; investigational; vet_approved | small molecule | Fluocinolone acetonide | Therapeutic strategy associated | Details |
| R0208 | DB00596 | approved | small molecule | Ulobetasol | Therapeutic strategy associated | Details |
| R0212 | DB00605 | approved; investigational | small molecule | Sulindac | Therapeutic strategy associated | Details |
| R0216 | DB00613 | approved; investigational | small molecule | Amodiaquine | Therapeutic strategy associated | Details |
| R0219 | DB00620 | approved; vet_approved | small molecule | Triamcinolone | Therapeutic strategy associated | Details |
| R0225 | DB00635 | approved; vet_approved | small molecule | Prednisone | Therapeutic strategy associated | Details |
| R0232 | DB00663 | approved; vet_approved | small molecule | Flumethasone | Therapeutic strategy associated | Details |
| R0234 | DB00669 | approved; investigational | small molecule | Sumatriptan | Therapeutic strategy associated | Details |
| R0239 | DB00688 | approved; investigational | small molecule | Mycophenolate mofetil | Therapeutic strategy associated | Details |
| R0242 | DB00693 | approved | small molecule | Fluorescein | Therapeutic strategy associated | Details |
| R0245 | DB00696 | approved | small molecule | Ergotamine | Therapeutic strategy associated | Details |
| R0250 | DB00712 | approved; investigational | small molecule | Flurbiprofen | Therapeutic strategy associated | Details |
| R0252 | DB00716 | approved; investigational | small molecule | Nedocromil | Therapeutic strategy associated | Details |
| R0254 | DB00724 | approved; investigational | small molecule | Imiquimod | Therapeutic strategy associated | Details |
| R0261 | DB00741 | approved; vet_approved | small molecule | Hydrocortisone | Therapeutic strategy associated | Details |
| R0263 | DB00744 | approved; investigational; withdrawn | small molecule | Zileuton | Therapeutic strategy associated | Details |
| R0264 | DB00749 | approved; investigational; vet_approved | small molecule | Etodolac | Therapeutic strategy associated | Details |
| R0265 | DB00751 | approved; investigational | small molecule | Epinastine | Therapeutic strategy associated | Details |
| R0270 | DB00764 | experimental | small molecule | Mometasone | Therapeutic strategy associated | Details |
| R0272 | DB00768 | approved | small molecule | Olopatadine | Therapeutic strategy associated | Details |
| R0273 | DB00769 | approved | small molecule | Hydrocortamate | Therapeutic strategy associated | Details |
| R0279 | DB00784 | approved | small molecule | Mefenamic acid | Therapeutic strategy associated | Details |
| R0281 | DB00788 | approved; vet_approved | small molecule | Naproxen | Therapeutic strategy associated | Details |
| R0282 | DB00795 | approved | small molecule | Sulfasalazine | Therapeutic strategy associated | Details |
| R0290 | DB00812 | approved; vet_approved | small molecule | Phenylbutazone | Therapeutic strategy associated | Details |
| R0291 | DB00814 | approved; vet_approved | small molecule | Meloxicam | Therapeutic strategy associated | Details |
| R0294 | DB00821 | approved; vet_approved; withdrawn | small molecule | Carprofen | Therapeutic strategy associated | Details |
| R0297 | DB00828 | approved | small molecule | Fosfomycin | Therapeutic strategy associated | Details |
| R0301 | DB00836 | approved | small molecule | Loperamide | Therapeutic strategy associated | Details |
| R0302 | DB00838 | approved | small molecule | Clocortolone | Therapeutic strategy associated | Details |
| R0305 | DB00843 | approved | small molecule | Donepezil | Therapeutic strategy associated | Details |
| R0306 | DB00845 | approved; investigational | small molecule | Clofazimine | Therapeutic strategy associated | Details |
| R0307 | DB00846 | approved | small molecule | Flurandrenolide | Therapeutic strategy associated | Details |
| R0311 | DB00860 | approved; vet_approved | small molecule | Prednisolone | Therapeutic strategy associated | Details |
| R0312 | DB00861 | approved; investigational | small molecule | Diflunisal | Therapeutic strategy associated | Details |
| R0316 | DB00870 | approved; withdrawn | small molecule | Suprofen | Therapeutic strategy associated | Details |
| R0318 | DB14596 | approved | small molecule | Loteprednol etabonate | Therapeutic strategy associated | Details |
| R0325 | DB00885 | approved; investigational | small molecule | Pemirolast | Therapeutic strategy associated | Details |
| R0327 | DB00896 | approved | small molecule | Rimexolone | Therapeutic strategy associated | Details |
| R0332 | DB00920 | approved | small molecule | Ketotifen | Therapeutic strategy associated | Details |
| R0338 | DB00936 | approved; investigational; vet_approved | small molecule | Salicylic acid | Therapeutic strategy associated | Details |
| R0340 | DB00939 | approved; vet_approved | small molecule | Meclofenamic acid | Therapeutic strategy associated | Details |