CMap Candidate Details

Structure:
CMap ID: C10052
Pert ID: BRD-K24201553
Compound Name: SB-269970
Targets: HTR7
MoA: Serotonin receptor antagonist
SMILES: CC1CCN(CC[C@H]2CCCN2S(=O)(=O)c2cccc(O)c2)CC1
InchiKey: HWKROQUZSKPIKQ-MRXNPFEDSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1566 BRD-K24201553 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
1904 BRD-K24201553 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2298 BRD-K24201553 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2632 BRD-K24201553 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41748 BRD-K24201553 A375 10 uM 6 h 0.23 0.97 0.08 0.28 0.98 0.39
41922 BRD-K24201553 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42962 BRD-K24201553 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43174 BRD-K24201553 MCF??7.00 10 uM 24 h -0.28 -1.17 0.48 0.37 1.3 1.51
43524 BRD-K24201553 NPC 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.14
43822 BRD-K24201553 PHH 10 uM 24 h -0.21 -0.86 0.02 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).