CMap Candidate Details

Structure:
CMap ID: C10061
Pert ID: BRD-K24219278
Compound Name: amineptine
Targets: SLC6A2; SLC6A4
MoA: Dopamine receptor agonist
SMILES: OC(=O)CCCCCCNC1c2ccccc2CCc2ccccc12
InchiKey: ONNOFKFOZAJDHT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121395 BRD-K24219278 HA1E 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121429 BRD-K24219278 HELA 0.37 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.1
121454 BRD-K24219278 HT29 0.125 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
121545 BRD-K24219278 YAPC 0.125 uM 24 h 0.26 1.08 0.22 -0.29 -0.97 0.45
129421 BRD-K24219278 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129542 BRD-K24219278 MCF??7.00 0.25 uM 24 h 0.24 1.01 0.11 0.0 0.0 0.0
129570 BRD-K24219278 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.91
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).