CMap Candidate Details

Structure:
CMap ID: C10068
Pert ID: BRD-K24240364
Compound Name: GYKI-52466
Targets: GRIA1
MoA: Kainate receptor antagonist; Glutamate receptor antagonist
SMILES: CC1=NN=C(c2ccc(N)cc2)c2cc3OCOc3cc2C1
InchiKey: LFBZZHVSGAHQPP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2855 BRD-K24240364 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3166 BRD-K24240364 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3477 BRD-K24240364 PC3 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.35
3754 BRD-K24240364 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44345 BRD-K24240364 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44552 BRD-K24240364 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45206 BRD-K24240364 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.39
45472 BRD-K24240364 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45793 BRD-K24240364 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
46021 BRD-K24240364 NPC 10 uM 24 h 0.22 0.91 0.03 0.26 0.91 0.23
46339 BRD-K24240364 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99768 BRD-K24240364 U2OS 10 uM 6 h -0.26 -1.07 0.27 -0.37 -1.25 1.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).