CMap Candidate Details

Structure:
CMap ID: C01017
Pert ID: BRD-A41630653
Compound Name: BRD-A41630653
Targets: SIGMAR1; SLC6A4
MoA: Glutamate receptor antagonist
SMILES: COc1ccc2CC3C4CCCC[C@@]4(CCN3C)c2c1
InchiKey: MKXZASYAUGDDCJ-VJFUWPCTSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
13725 BRD-A41630653 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
14055 BRD-A41630653 A549 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
14377 BRD-A41630653 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
14939 BRD-A41630653 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15261 BRD-A41630653 MCF??7.00 10 uM 24 h -0.2 -0.85 0.01 -0.35 -1.17 1.14
15702 BRD-A41630653 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
16132 BRD-A41630653 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).