CMap Candidate Details

Structure:
CMap ID: C01019
Pert ID: BRD-A41692738
Compound Name: TGX-221
Targets: PIK3CB
MoA: PI3K inhibitor
SMILES: CC(Nc1ccccc1)c1cc(C)cn2c1nc(cc2=O)N1CCOCC1
InchiKey: CPRAGQJXBLMUEL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33747 BRD-A41692738 A549 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.24
33991 BRD-A41692738 ASC 10 uM 24 h -0.3 -1.24 0.65 0.0 0.0 0.0
35512 BRD-A41692738 NEU 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.16
35685 BRD-A41692738 NPC 10 uM 24 h -0.35 -1.46 1.43 0.0 0.0 0.0
36149 BRD-A41692738 PHH 10 uM 24 h -0.28 -1.17 0.48 -0.26 -0.88 0.25
36443 BRD-A41692738 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36737 BRD-A41692738 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92021 BRD-A41692738 BT20 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92102 BRD-A41692738 HCC515 10 uM 24 h 0.24 0.99 0.1 -0.31 -1.05 0.72
92138 BRD-A41692738 HS578T 3.33 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
92190 BRD-A41692738 HT29 0.37 uM 24 h 0.23 0.95 0.07 0.0 0.0 0.0
92232 BRD-A41692738 MCF10A 3.33 uM 3 h 0.25 1.05 0.16 -0.22 -0.75 0.07
92256 BRD-A41692738 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92311 BRD-A41692738 MDAMB231 0.04 uM 3 h -0.21 -0.88 0.03 0.24 0.87 0.17
92368 BRD-A41692738 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115643 BRD-A41692738 A375 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.78
115719 BRD-A41692738 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115804 BRD-A41692738 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115930 BRD-A41692738 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).