CMap Candidate Details

Structure:
CMap ID: C10194
Pert ID: BRD-K24616672
Compound Name: procaine
Targets: HTR3A
MoA: HMGCR inhibitor
SMILES: CCN(CC)CCOC(=O)c1ccc(N)cc1
InchiKey: MFDFERRIHVXMIY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120961 BRD-K24616672 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121003 BRD-K24616672 HELA 0.04 uM 3 h 0.21 0.87 0.01 0.0 0.0 0.0
121049 BRD-K24616672 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121117 BRD-K24616672 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129099 BRD-K24616672 A375 2.22 uM 24 h 0.23 0.95 0.06 0.0 0.0 0.0
129119 BRD-K24616672 A549 2.22 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.69
129139 BRD-K24616672 HA1E 2.22 uM 24 h 0.0 0.0 0.0 -0.25 -0.84 0.18
129195 BRD-K24616672 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129222 BRD-K24616672 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).