CMap Candidate Details

Structure:
CMap ID: C01021
Pert ID: BRD-A41833852
Compound Name: naloxone
Targets: OPRD1; OPRK1; OPRM1
MoA: Opioid receptor antagonist
SMILES: Oc1ccc2CC3N(CC=C)CCC4(C5Oc1c24)C3(O)CCC5=NNC(=O)c6ccccc6
InchiKey: AKXCFAYOTIEFOH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4172 BRD-A41833852 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4524 BRD-A41833852 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4619 BRD-A41833852 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4856 BRD-A41833852 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37077 BRD-A41833852 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37237 BRD-A41833852 A549 10 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
37499 BRD-A41833852 ASC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.16 1.11
38015 BRD-A41833852 HT29 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.28
38151 BRD-A41833852 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38349 BRD-A41833852 NPC 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.14
38639 BRD-A41833852 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).