CMap Candidate Details

Structure:
CMap ID: C10216
Pert ID: BRD-K24675965
Compound Name: LY-288513
Targets: CCKBR
MoA: CCK receptor antagonist
SMILES: Brc1ccc(NC(=O)N2NC(=O)[C@H]([C@@H]2c2ccccc2)c2ccccc2)cc1
InchiKey: LMUQHXHWJWQXSD-PMACEKPBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2999 BRD-K24675965 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3346 BRD-K24675965 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.25 1.35
3606 BRD-K24675965 PC3 10 uM 6 h 0.0 0.0 0.0 0.22 0.78 0.07
3755 BRD-K24675965 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39105 BRD-K24675965 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39434 BRD-K24675965 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39651 BRD-K24675965 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39967 BRD-K24675965 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40244 BRD-K24675965 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40601 BRD-K24675965 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40773 BRD-K24675965 NEU 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.36 2.02
41074 BRD-K24675965 NPC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.06 0.74
41405 BRD-K24675965 SKB 10 uM 24 h -0.32 -1.34 0.98 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).