CMap Candidate Details

Structure:
CMap ID: C10234
Pert ID: BRD-K24723746
Compound Name: solifenacin-succinate
Targets: CHRM1; CHRM2; CHRM3
MoA: Acetylcholine receptor antagonist
SMILES: O=C(O[C@H]1CN2CCC1CC2)N1CCc2ccccc2[C@@H]1c1ccccc1
InchiKey: FBOUYBDGKBSUES-VXKWHMMOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
120871 BRD-K24723746 A375 10 uM 24 h -0.27 -1.11 0.37 0.0 0.0 0.0
120889 BRD-K24723746 A549 10 uM 24 h 0.24 0.99 0.1 0.37 1.31 1.59
120963 BRD-K24723746 HEK293 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121052 BRD-K24723746 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121120 BRD-K24723746 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129141 BRD-K24723746 HA1E 0.03 uM 24 h -0.24 -0.98 0.13 0.0 0.0 0.0
129168 BRD-K24723746 HELA 0.08 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
129197 BRD-K24723746 HT29 0.01 uM 24 h -0.25 -1.03 0.19 0.0 0.0 0.0
129223 BRD-K24723746 PC3 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).