CMap Candidate Details

Structure:
CMap ID: C10251
Pert ID: BRD-K24771047
Compound Name: ampalex
Targets: GRIA1
MoA: Glutamate receptor agonist
SMILES: O=C(N1CCCCC1)c1ccc2nccnc2c1
InchiKey: ANDGGVOPIJEHOF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121948 BRD-K24771047 HEK293 0.125 uM 24 h -0.31 -1.31 0.82 0.0 0.0 0.0
121998 BRD-K24771047 HT29 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.06
122031 BRD-K24771047 HUVEC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122131 BRD-K24771047 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130178 BRD-K24771047 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130193 BRD-K24771047 A549 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130215 BRD-K24771047 HA1E 0.01 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.3
130277 BRD-K24771047 HELA 0.03 uM 24 h -0.23 -0.98 0.12 0.0 0.0 0.0
130333 BRD-K24771047 JURKAT 0.08 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.43
130386 BRD-K24771047 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130425 BRD-K24771047 MCF??7.00 2.22 uM 24 h 0.3 1.26 0.56 -0.25 -0.83 0.15
130472 BRD-K24771047 PC3 0.25 uM 24 h -0.19 -0.8 0.0 0.0 0.0 0.0
130488 BRD-K24771047 THP1 2.22 uM 24 h -0.26 -1.09 0.32 0.26 0.91 0.23
130513 BRD-K24771047 YAPC 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).