CMap Candidate Details

Structure:
CMap ID: C10345
Pert ID: BRD-K25114078
Compound Name: aminoguanidine
Targets: NOS2
MoA: Nitric oxide synthase inhibitor
SMILES: NNC(N)=N
InchiKey: HAMNKKUPIHEESI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
119929 BRD-K25114078 A375 0.04 uM 24 h -0.31 -1.29 0.77 0.38 1.33 1.72
119963 BRD-K25114078 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120011 BRD-K25114078 HA1E 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120078 BRD-K25114078 HT29 0.125 uM 24 h 0.0 0.0 0.0 0.3 1.06 0.59
120125 BRD-K25114078 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
120202 BRD-K25114078 YAPC 1.11 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.1
128822 BRD-K25114078 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.13
128839 BRD-K25114078 PC3 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).