CMap Candidate Details

Structure:
CMap ID: C10384
Pert ID: BRD-K25224017
Compound Name: pirenperone
Targets: HTR2A
MoA: Serotonin receptor antagonist
SMILES: Cc1nc2ccccn2c(=O)c1CCN1CCC(CC1)C(=O)c1ccc(F)cc1
InchiKey: HXCNRYXBZNHDNE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5196 BRD-K25224017 A375 10 uM 6 h -0.19 -0.77 0.0 0.32 1.12 0.77
5311 BRD-K25224017 HA1E 10 uM 24 h 0.17 0.71 0.0 -0.3 -1.02 0.61
5763 BRD-K25224017 HCC515 10 uM 6 h 0.29 1.23 0.5 0.0 0.0 0.0
6012 BRD-K25224017 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6386 BRD-K25224017 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24660 BRD-K25224017 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37620 BRD-K25224017 ASC 10 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.21
37882 BRD-K25224017 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.79 0.1
38448 BRD-K25224017 NPC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.3
38930 BRD-K25224017 SKB 10 uM 24 h 0.21 0.86 0.01 -0.33 -1.12 0.96
51597 BRD-K25224017 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51927 BRD-K25224017 PC3 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
99773 BRD-K25224017 U2OS 10 uM 6 h -0.21 -0.87 0.02 0.28 0.99 0.41
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).