CMap Candidate Details
Structure:
| CMap ID: | C10406 |
| Pert ID: | BRD-K25310650 |
| Compound Name: | ormetoprim |
| Targets: | P2RX2; P2RX3 |
| MoA: | Bacterial antifolate |
| SMILES: | COc1cc(C)c(Cc2cnc(N)nc2N)cc1OC |
| InchiKey: | KEEYRKYKLYARHO-UHFFFAOYSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24422 | BRD-K25310650 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24661 | BRD-K25310650 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24886 | BRD-K25310650 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.35 | -1.16 | 1.11 |
| 25242 | BRD-K25310650 | PC3 | 10 uM | 6 h | -0.37 | -1.54 | 1.43 | -0.3 | -1.01 | 0.56 |
| 25497 | BRD-K25310650 | VCAP | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |