CMap Candidate Details

Structure:
CMap ID: C01043
Pert ID: BRD-A42571354
Compound Name: cetirizine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: OC(=O)COCCN1CCN(CC1)C(c1ccccc1)c1ccc(Cl)cc1
InchiKey: ZKLPARSLTMPFCP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4174 BRD-A42571354 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4306 BRD-A42571354 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4756 BRD-A42571354 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4858 BRD-A42571354 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
20197 BRD-A42571354 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20531 BRD-A42571354 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21002 BRD-A42571354 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37080 BRD-A42571354 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37342 BRD-A42571354 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38352 BRD-A42571354 NPC 10 uM 24 h -0.21 -0.88 0.03 -0.27 -0.91 0.3
38641 BRD-A42571354 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).